메뉴 건너뛰기




Volumn 174, Issue 4, 2004, Pages 490-503

From molecular biology to pharmacogenetics: A review of the literature on antidepressant treatment and suggestions of possible candidate genes

Author keywords

Antidepressant; Bipolar disorder; Depression; Pharmacogenetics; Serotonin

Indexed keywords

4 AMINOBUTYRIC ACID; ANTIDEPRESSANT AGENT; CATECHOLAMINE; CITALOPRAM; DOPAMINE; FLUOXETINE; FLUVOXAMINE; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; MIRTAZAPINE; MOCLOBEMIDE; MONOAMINE; NEUROKININ; NORADRENALIN; NORADRENALIN UPTAKE INHIBITOR; PAROXETINE; SEROTONIN; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; SUBSTANCE P; TRICYCLIC ANTIDEPRESSANT AGENT; TRYPTOPHAN HYDROXYLASE; VENLAFAXINE;

EID: 4344686766     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-004-1822-x     Document Type: Review
Times cited : (61)

References (146)
  • 1
    • 0034030898 scopus 로고    scopus 로고
    • Practice guideline for the treatment of patients with major depressive disorder
    • American Psychiatric Association
    • American Psychiatric Association (2000) Practice guideline for the treatment of patients with major depressive disorder (revision). American Psychiatric Association. Am J Psychiatry 157:1-45
    • (2000) Am J Psychiatry , vol.157 , pp. 1-45
  • 2
    • 0002311563 scopus 로고    scopus 로고
    • Genetic variability in the promoter region of the serotonin transporter gene is associated with clinical remission of major depression after long term treatment with citalopram
    • World Federation of Societies of Biological Psychiatry, Berlin, Germany
    • Arias B, Catalan R, Gasto C, Imaz ML, Gutierrez B, Pintor L, Fananas L (2001) Genetic variability in the promoter region of the serotonin transporter gene is associated with clinical remission of major depression after long term treatment with citalopram. World Federation of Societies of Biological Psychiatry, vol 2(1). World Journal of Biological Psychiatry, Berlin, Germany, p 9S
    • (2001) World Journal of Biological Psychiatry , vol.2 , Issue.1
    • Arias, B.1    Catalan, R.2    Gasto, C.3    Imaz, M.L.4    Gutierrez, B.5    Pintor, L.6    Fananas, L.7
  • 5
    • 0035056928 scopus 로고    scopus 로고
    • Possible influence of the insertion/deletion polymorphism in the angiotensin I-converting enzyme gene on therapeutic outcome in affective disorders
    • Baghai TC, Schule C, Zwanzger P, Minov C, Schwarz MJ, de Jonge S, Rupprecht R, Bondy B (2001) Possible influence of the insertion/deletion polymorphism in the angiotensin I-converting enzyme gene on therapeutic outcome in affective disorders. Mol Psychiatry 6:258-259
    • (2001) Mol Psychiatry , vol.6 , pp. 258-259
    • Baghai, T.C.1    Schule, C.2    Zwanzger, P.3    Minov, C.4    Schwarz, M.J.5    De Jonge, S.6    Rupprecht, R.7    Bondy, B.8
  • 7
    • 0028278638 scopus 로고
    • The functional role of monoamine oxidases A and B in the mammalian central nervous system
    • Berry MD, Juorio AV, Paterson IA (1994) The functional role of monoamine oxidases A and B in the mammalian central nervous system. Prog Neurobiol 42:375-391
    • (1994) Prog Neurobiol , vol.42 , pp. 375-391
    • Berry, M.D.1    Juorio, A.V.2    Paterson, I.A.3
  • 8
    • 0035503323 scopus 로고    scopus 로고
    • Physiological genomics of antidepressant targets: Keeping the periphery in mind
    • Blakely RD (2001) Physiological genomics of antidepressant targets: keeping the periphery in mind. J Neurosci 21:8319-8323
    • (2001) J Neurosci , vol.21 , pp. 8319-8323
    • Blakely, R.D.1
  • 9
    • 0028287265 scopus 로고
    • Current advances and trends in the treatment of depression
    • Blier P, de Montigny C (1994) Current advances and trends in the treatment of depression. Trends Pharmacol Sci 15:220-226
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 220-226
    • Blier, P.1    De Montigny, C.2
  • 12
    • 0031751159 scopus 로고    scopus 로고
    • Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. A quantitative in situ hybridization study
    • Boyer PA, Skolnick P, Fossom LH (1998) Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. A quantitative in situ hybridization study. J Mol Neurosci 10:219-233
    • (1998) J Mol Neurosci , vol.10 , pp. 219-233
    • Boyer, P.A.1    Skolnick, P.2    Fossom, L.H.3
  • 13
    • 0022877399 scopus 로고
    • Assignment of the catechol-O-methyltransferase gene to human chromosome 22 in somatic cell hybrids
    • Brahe C, Bannetta P, Meera Khan P, Arwert F, Serra A (1986) Assignment of the catechol-O-methyltransferase gene to human chromosome 22 in somatic cell hybrids. Hum Genet 74:230-234
    • (1986) Hum Genet , vol.74 , pp. 230-234
    • Brahe, C.1    Bannetta, P.2    Meera Khan, P.3    Arwert, F.4    Serra, A.5
  • 14
    • 0028577297 scopus 로고
    • Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4- phenylpyridinium
    • Buck KJ, Amara SG (1994) Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium. Proc Natl Acad Sci USA 91:12584-12588
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12584-12588
    • Buck, K.J.1    Amara, S.G.2
  • 16
    • 0035677108 scopus 로고    scopus 로고
    • Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors
    • Bymaster FP, Dreshfield-Ahmad LJ, Threlkeld PG, Shaw JL, Thompson L, Nelson DL, Hemrick-Luecke SK, Wong DT (2001) Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology 25:871-880
    • (2001) Neuropsychopharmacology , vol.25 , pp. 871-880
    • Bymaster, F.P.1    Dreshfield-Ahmad, L.J.2    Threlkeld, P.G.3    Shaw, J.L.4    Thompson, L.5    Nelson, D.L.6    Hemrick-Luecke, S.K.7    Wong, D.T.8
  • 17
    • 0036316456 scopus 로고    scopus 로고
    • Involvement of NF-Y and Sp1 in basal and cAMP-stimulated transcriptional activation of the tryptophan hydroxylase (TPH) gene in the pineal gland
    • Cote F, Schussler N, Boularand S, Peirotes A, Thevenot E, Mallet J, Vodjdani G (2002) Involvement of NF-Y and Sp1 in basal and cAMP-stimulated transcriptional activation of the tryptophan hydroxylase (TPH) gene in the pineal gland. J Neurochem 81:673-685
    • (2002) J Neurochem , vol.81 , pp. 673-685
    • Cote, F.1    Schussler, N.2    Boularand, S.3    Peirotes, A.4    Thevenot, E.5    Mallet, J.6    Vodjdani, G.7
  • 18
    • 0025734886 scopus 로고
    • Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3-p14 by in situ hybridization
    • Craig SP, Boularand S, Darmon MC, Mallet J, Craig IW (1991) Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3-p14 by in situ hybridization. Cytogenet Cell Genet 56:157-159
    • (1991) Cytogenet Cell Genet , vol.56 , pp. 157-159
    • Craig, S.P.1    Boularand, S.2    Darmon, M.C.3    Mallet, J.4    Craig, I.W.5
  • 19
    • 0035111686 scopus 로고    scopus 로고
    • Discriminative stimulus effects of centrally administered isoproterenol in rats: Mediation by beta-1 adrenergic receptors
    • Crissman AM, Makhay MM, O'Donnell JM (2001) Discriminative stimulus effects of centrally administered isoproterenol in rats: mediation by beta-1 adrenergic receptors. Psychopharmacology 154:70-75
    • (2001) Psychopharmacology , vol.154 , pp. 70-75
    • Crissman, A.M.1    Makhay, M.M.2    O'Donnell, J.M.3
  • 20
    • 0034074370 scopus 로고    scopus 로고
    • 1A and beyond: The role of serotonin and its receptors in depression and the antidepressant response
    • 1A and beyond: the role of serotonin and its receptors in depression and the antidepressant response. Hum Psychopharmacol 15:113-135
    • (2000) Hum Psychopharmacol , vol.15 , pp. 113-135
    • Cryan, J.F.1    Leonard, B.E.2
  • 21
    • 0034913629 scopus 로고    scopus 로고
    • Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs
    • Cryan JF, Dalvi A, Jin SH, Hirsch BR, Lucki I, Thomas SA (2001) Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. J Pharmacol Exp Ther 298:651-657
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 651-657
    • Cryan, J.F.1    Dalvi, A.2    Jin, S.H.3    Hirsch, B.R.4    Lucki, I.5    Thomas, S.A.6
  • 24
    • 0242575121 scopus 로고    scopus 로고
    • Investigation of polymorphism in the MDR1 gene and antidepressant-induced mania
    • De Luca V, Mundo E, Trakalo J, Wong GW, Kennedy JL (2003) Investigation of polymorphism in the MDR1 gene and antidepressant-induced mania. Pharmacogenomics J 3:297-299
    • (2003) Pharmacogenomics J , vol.3 , pp. 297-299
    • De Luca, V.1    Mundo, E.2    Trakalo, J.3    Wong, G.W.4    Kennedy, J.L.5
  • 25
    • 0033372808 scopus 로고    scopus 로고
    • A promoter-associated variable number tandem repeat
    • A promoter-associated variable number tandem repeat. Hum Genet 105:542-551
    • (1999) Hum Genet , vol.105 , pp. 542-551
    • Denney, R.M.1    Koch, H.2    Craig, I.W.3
  • 26
    • 0035068099 scopus 로고    scopus 로고
    • Modification of norepinephrine and serotonin, but not dopamine, neuron firing by sustained bupropion treatment
    • Dong J, Blier P (2001) Modification of norepinephrine and serotonin, but not dopamine, neuron firing by sustained bupropion treatment. Psychopharmacology 155:52-57
    • (2001) Psychopharmacology , vol.155 , pp. 52-57
    • Dong, J.1    Blier, P.2
  • 27
    • 4344618699 scopus 로고    scopus 로고
    • The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder
    • Durham LK, Webb SM, Milos PM, Clary CM, Seymour AB (2003) The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder. Psychopharmacology 4:4
    • (2003) Psychopharmacology , vol.4 , pp. 4
    • Durham, L.K.1    Webb, S.M.2    Milos, P.M.3    Clary, C.M.4    Seymour, A.B.5
  • 28
    • 0037247185 scopus 로고    scopus 로고
    • Chronic fluoxetine induces opposite changes in G protein coupling at pre and postsynaptic 5-HT(1A) receptors in rat brain
    • Elena Castro M, Diaz A, del Olmo E, Pazos A (2003) Chronic fluoxetine induces opposite changes in G protein coupling at pre and postsynaptic 5-HT(1A) receptors in rat brain. Neuropharmacology 44:93-101
    • (2003) Neuropharmacology , vol.44 , pp. 93-101
    • Elena Castro, M.1    Diaz, A.2    Del Olmo, E.3    Pazos, A.4
  • 29
    • 0028177555 scopus 로고
    • Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster. Implications for structure-function relationships
    • Ewart GD, Cannell D, Cox GB, Howells AJ (1994) Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster. Implications for structure-function relationships. J Biol Chem 269:10370-10377
    • (1994) J Biol Chem , vol.269 , pp. 10370-10377
    • Ewart, G.D.1    Cannell, D.2    Cox, G.B.3    Howells, A.J.4
  • 33
    • 0033555898 scopus 로고    scopus 로고
    • Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity
    • Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG (1999) Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283:397-401
    • (1999) Science , vol.283 , pp. 397-401
    • Gainetdinov, R.R.1    Wetsel, W.C.2    Jones, S.R.3    Levin, E.D.4    Jaber, M.5    Caron, M.G.6
  • 34
    • 0027196238 scopus 로고
    • TaqI RFLP at norepinephrine transporter protein (NET) locus
    • Gelernter J, Kruger S, Kidd KK, Amara S (1993) TaqI RFLP at norepinephrine transporter protein (NET) locus. Hum Mol Genet 2:820
    • (1993) Hum Mol Genet , vol.2 , pp. 820
    • Gelernter, J.1    Kruger, S.2    Kidd, K.K.3    Amara, S.4
  • 35
    • 0036788326 scopus 로고    scopus 로고
    • Inhibition of norepinephrine uptake in patients with major depression treated with paroxetine
    • Gilmor ML, Owens MJ, Nemeroff CB (2002) Inhibition of norepinephrine uptake in patients with major depression treated with paroxetine. Am J Psychiatry 159:1702-1710
    • (2002) Am J Psychiatry , vol.159 , pp. 1702-1710
    • Gilmor, M.L.1    Owens, M.J.2    Nemeroff, C.B.3
  • 36
    • 0027049060 scopus 로고
    • Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
    • Giros B, el Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, Caron MG (1992) Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. Mol Pharmacol 42:383-390
    • (1992) Mol Pharmacol , vol.42 , pp. 383-390
    • Giros, B.1    El Mestikawy, S.2    Godinot, N.3    Zheng, K.4    Han, H.5    Yang-Feng, T.6    Caron, M.G.7
  • 37
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • Giros B, Jaber M, Jones SR, Wightman RM, Caron MG (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379:606-612
    • (1996) Nature , vol.379 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 38
    • 0026518652 scopus 로고
    • Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1-q11.2
    • Grossman MH, Emanuel BS, Budarf ML (1992) Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1-q11.2. Genomics 12:822-825
    • (1992) Genomics , vol.12 , pp. 822-825
    • Grossman, M.H.1    Emanuel, B.S.2    Budarf, M.L.3
  • 40
    • 0037064272 scopus 로고    scopus 로고
    • Functional effects of chronic electroconvulsive shock on serotonergic 5-HT(1A) and 5-HT(1B) receptor activity in rat hippocampus and hypothalamus
    • Gur E, Dremencov E, Garcia F, Van de Kar LD, Lerer B, Newman ME (2002) Functional effects of chronic electroconvulsive shock on serotonergic 5-HT(1A) and 5-HT(1B) receptor activity in rat hippocampus and hypothalamus. Brain Res 952:52-60
    • (2002) Brain Res , vol.952 , pp. 52-60
    • Gur, E.1    Dremencov, E.2    Garcia, F.3    Van De Kar, L.D.4    Lerer, B.5    Newman, M.E.6
  • 41
    • 0037382381 scopus 로고    scopus 로고
    • Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors
    • Harkin A, Connor TJ, Walsh M, St John N, Kelly JP (2003) Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors. Neuropharmacology 44:616-623
    • (2003) Neuropharmacology , vol.44 , pp. 616-623
    • Harkin, A.1    Connor, T.J.2    Walsh, M.3    St John, N.4    Kelly, J.P.5
  • 42
    • 0037151298 scopus 로고    scopus 로고
    • Reduction of cGMP and nitric oxide has antidepressant-like effects in the forced swimming test in rats
    • Heiberg IL, Wegener G, Rosenberg R (2002) Reduction of cGMP and nitric oxide has antidepressant-like effects in the forced swimming test in rats. Behav Brain Res 134:479-484
    • (2002) Behav Brain Res , vol.134 , pp. 479-484
    • Heiberg, I.L.1    Wegener, G.2    Rosenberg, R.3
  • 44
    • 0028206468 scopus 로고
    • Evaluation of nefazodone as a serotonin uptake inhibitor and a serotonin antagonist in vivo
    • Hemrick-Luecke SK, Snoddy HD, Fuller RW (1994) Evaluation of nefazodone as a serotonin uptake inhibitor and a serotonin antagonist in vivo. Life Sci 55:479-83
    • (1994) Life Sci , vol.55 , pp. 479-483
    • Hemrick-Luecke, S.K.1    Snoddy, H.D.2    Fuller, R.W.3
  • 46
    • 0036250544 scopus 로고    scopus 로고
    • Reduced aggression in mice lacking the serotonin transporter
    • Holmes A, Murphy DL, Crawley JN (2002) Reduced aggression in mice lacking the serotonin transporter. Psychopharmacology 161:160-167
    • (2002) Psychopharmacology , vol.161 , pp. 160-167
    • Holmes, A.1    Murphy, D.L.2    Crawley, J.N.3
  • 47
    • 85030939872 scopus 로고    scopus 로고
    • Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior
    • Holmes A, Yang RJ, Lesch KP, Crawley JN, Murphy DL (2003) Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior. Neuropsychopharmacology 10:10
    • (2003) Neuropsychopharmacology , vol.10 , pp. 10
    • Holmes, A.1    Yang, R.J.2    Lesch, K.P.3    Crawley, J.N.4    Murphy, D.L.5
  • 48
    • 0036050904 scopus 로고    scopus 로고
    • Association study of angiotensin I-converting enzyme polymorphism and symptomatology and antidepressant response in major depressive disorders
    • Hong CJ, Wang YC, Tsai SJ (2002) Association study of angiotensin I-converting enzyme polymorphism and symptomatology and antidepressant response in major depressive disorders. J Neural Transm 109:1209-1214
    • (2002) J Neural Transm , vol.109 , pp. 1209-1214
    • Hong, C.J.1    Wang, Y.C.2    Tsai, S.J.3
  • 50
    • 0024316847 scopus 로고
    • Characterization of acute N-ethyl-3,4-methylenedioxyamphetamine (MDE) action on the central serotonergic system
    • Johnson M, Hanson GR, Gibb JW (1989) Characterization of acute N-ethyl-3,4-methylenedioxyamphetamine (MDE) action on the central serotonergic system. Biochem Pharmacol 38:4333-4338
    • (1989) Biochem Pharmacol , vol.38 , pp. 4333-4338
    • Johnson, M.1    Hanson, G.R.2    Gibb, J.W.3
  • 55
    • 0036205443 scopus 로고    scopus 로고
    • Up-regulation of tryptophan hydroxylase expression and serotonin synthesis by sertraline
    • Kim SW, Park SY, Hwang O (2002) Up-regulation of tryptophan hydroxylase expression and serotonin synthesis by sertraline. Mol Pharmacol 61:778-785
    • (2002) Mol Pharmacol , vol.61 , pp. 778-785
    • Kim, S.W.1    Park, S.Y.2    Hwang, O.3
  • 56
    • 0033921969 scopus 로고    scopus 로고
    • Rat beta 1-adrenergic receptor regulatory region containing consensus AP-2 elements recognizes novel transactivator proteins
    • Kirigiti P, Yang YF, Li X, Li B, Midson CN, Machida CA (2000) Rat beta 1-adrenergic receptor regulatory region containing consensus AP-2 elements recognizes novel transactivator proteins. Mol Cell Biol Res Commun 3:181-192
    • (2000) Mol Cell Biol Res Commun , vol.3 , pp. 181-192
    • Kirigiti, P.1    Yang, Y.F.2    Li, X.3    Li, B.4    Midson, C.N.5    Machida, C.A.6
  • 57
    • 0034751703 scopus 로고    scopus 로고
    • Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder
    • Kirov G, Lowry CA, Stephens M, Oldfield S, O'Donovan MC, Lightman SL, Owen MJ (2001) Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder. Mol Psychiatry 6:671-677
    • (2001) Mol Psychiatry , vol.6 , pp. 671-677
    • Kirov, G.1    Lowry, C.A.2    Stephens, M.3    Oldfield, S.4    O'Donovan, M.C.5    Lightman, S.L.6    Owen, M.J.7
  • 58
  • 60
    • 0031423428 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphisms: Ethnic difference and possible association with bipolar affective disorder
    • Kunugi H, Hattori M, Kato T, Tatsumi M, Sakai T, Sasaki T, Hirose T, Nanko S (1997) Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder. Mol Psychiatry 2:457-462
    • (1997) Mol Psychiatry , vol.2 , pp. 457-462
    • Kunugi, H.1    Hattori, M.2    Kato, T.3    Tatsumi, M.4    Sakai, T.5    Sasaki, T.6    Hirose, T.7    Nanko, S.8
  • 61
    • 0028942723 scopus 로고
    • Organization and sequence of the human P gene and identification of a new family of transport proteins
    • Lee ST, Nicholls RD, Jong MT, Fukai K, Spritz RA (1995) Organization and sequence of the human P gene and identification of a new family of transport proteins. Genomics 26:354-363
    • (1995) Genomics , vol.26 , pp. 354-363
    • Lee, S.T.1    Nicholls, R.D.2    Jong, M.T.3    Fukai, K.4    Spritz, R.A.5
  • 66
    • 0027933179 scopus 로고
    • Cell-type-specific expression of catecholamine transporters in the rat brain
    • Lorang D, Amara SG, Simerly RB (1994) Cell-type-specific expression of catecholamine transporters in the rat brain. J Neurosci 14:4903-4914
    • (1994) J Neurosci , vol.14 , pp. 4903-4914
    • Lorang, D.1    Amara, S.G.2    Simerly, R.B.3
  • 67
    • 0000587671 scopus 로고
    • The serotonin hypothesis of major depression
    • Bloom FE, Kupfer DJ (eds) Raven, New York
    • Maes M, Meltzer HY (1995) The serotonin hypothesis of major depression. In: Bloom FE, Kupfer DJ (eds) Psychopharmacology: the fourth generation of progress. Raven, New York, pp 933-944
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 68
    • 0037218037 scopus 로고    scopus 로고
    • Role of pharmacogenomics in individualising treatment with SSRIs
    • Mancama D, Kerwin RW (2003) Role of pharmacogenomics in individualising treatment with SSRIs. CNS Drugs 17:143-151
    • (2003) CNS Drugs , vol.17 , pp. 143-151
    • Mancama, D.1    Kerwin, R.W.2
  • 70
    • 85047685329 scopus 로고    scopus 로고
    • Polymorphisms in the 3′-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression
    • Miller GM, Madras BK (2002) Polymorphisms in the 3′-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression. Mol Psychiatry 7:44-55
    • (2002) Mol Psychiatry , vol.7 , pp. 44-55
    • Miller, G.M.1    Madras, B.K.2
  • 74
    • 0034998460 scopus 로고    scopus 로고
    • The role of serotonin transporter protein gene in antidepressant-induced mania in bipolar disorder
    • Mundo E, Walker M, Cate T, Macciardi F, Kennedy JL (2001) The role of serotonin transporter protein gene in antidepressant-induced mania in bipolar disorder. Arch Gen Psychiatry 58:539-544
    • (2001) Arch Gen Psychiatry , vol.58 , pp. 539-544
    • Mundo, E.1    Walker, M.2    Cate, T.3    Macciardi, F.4    Kennedy, J.L.5
  • 75
    • 4344604195 scopus 로고    scopus 로고
    • Effects of the serotonin transporter promoter polymorphism on paroxetine and mirtazapine efficacy and side effects in geriatric major depression
    • Hospital TZH (ed) New York
    • Murphy G, Hollander S, Rodrigues H, Schatzberg A (2003a) Effects of the serotonin transporter promoter polymorphism on paroxetine and mirtazapine efficacy and side effects in geriatric major depression. In: Hospital TZH (ed) Pharmacogenetics in psychiatry meeting, vol 1, New York
    • (2003) Pharmacogenetics in Psychiatry Meeting , vol.1
    • Murphy, G.1    Hollander, S.2    Rodrigues, H.3    Schatzberg, A.4
  • 77
    • 0032831747 scopus 로고    scopus 로고
    • The GABA(B) receptor antagonist CGP36742 improves learned helplessness in rats
    • Nakagawa Y, Sasaki A, Takashima T (1999) The GABA(B) receptor antagonist CGP36742 improves learned helplessness in rats. Eur J Pharmacol 381:1-7
    • (1999) Eur J Pharmacol , vol.381 , pp. 1-7
    • Nakagawa, Y.1    Sasaki, A.2    Takashima, T.3
  • 78
    • 0037204736 scopus 로고    scopus 로고
    • Repeated imipramine and electroconvulsive shock increase alpha(1A)-adrenoceptor mRNA level in rat prefrontal cortex
    • Nalepa I, Kreiner G, Kowalska M, Sanak M, Zelek-Molik A, Vetulani J (2002) Repeated imipramine and electroconvulsive shock increase alpha(1A)-adrenoceptor mRNA level in rat prefrontal cortex. Eur J Pharmacol 444:151-159
    • (2002) Eur J Pharmacol , vol.444 , pp. 151-159
    • Nalepa, I.1    Kreiner, G.2    Kowalska, M.3    Sanak, M.4    Zelek-Molik, A.5    Vetulani, J.6
  • 79
    • 0028860268 scopus 로고
    • Heterotrimeric G proteins: Organizers of transmembrane signals
    • Neer EJ (1995) Heterotrimeric G proteins: organizers of transmembrane signals. Cell 80:249-257
    • (1995) Cell , vol.80 , pp. 249-257
    • Neer, E.J.1
  • 80
    • 0031128233 scopus 로고    scopus 로고
    • Sequence, splice site and population frequency distribution analyses of the polymorphic human tryptophan hydroxylase intron 7
    • Nielsen DA, Jenkins GL, Stefanisko KM, Jefferson KK, Goldman D (1997) Sequence, splice site and population frequency distribution analyses of the polymorphic human tryptophan hydroxylase intron 7. Brain Res Mol Brain Res 45:145-148
    • (1997) Brain Res Mol Brain Res , vol.45 , pp. 145-148
    • Nielsen, D.A.1    Jenkins, G.L.2    Stefanisko, K.M.3    Jefferson, K.K.4    Goldman, D.5
  • 82
    • 0032867437 scopus 로고    scopus 로고
    • Norepinephrine transporter gene polymorphism is not associated with susceptibility to major depression
    • Owen D, Du L, Bakish D, Lapierre YD, Hrdina PD (1999) Norepinephrine transporter gene polymorphism is not associated with susceptibility to major depression. Psychiatry Res 87:1-5
    • (1999) Psychiatry Res , vol.87 , pp. 1-5
    • Owen, D.1    Du, L.2    Bakish, D.3    Lapierre, Y.D.4    Hrdina, P.D.5
  • 83
    • 0026433037 scopus 로고
    • Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter
    • Pacholczyk T, Blakely RD, Amara SG (1991) Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Nature 350:350-354
    • (1991) Nature , vol.350 , pp. 350-354
    • Pacholczyk, T.1    Blakely, R.D.2    Amara, S.G.3
  • 85
    • 0342894667 scopus 로고    scopus 로고
    • Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment
    • Perez V, Gilaberte I, Faries D, Alvarez E, Artigas F (1997) Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment. Lancet 349:1594-1597
    • (1997) Lancet , vol.349 , pp. 1594-1597
    • Perez, V.1    Gilaberte, I.2    Faries, D.3    Alvarez, E.4    Artigas, F.5
  • 88
    • 0036100387 scopus 로고    scopus 로고
    • Effects of nitric oxide synthase inhibitors 7-NI, L-NAME, and L-NOARG in staircase test
    • Pokk P, Vali M (2002a) Effects of nitric oxide synthase inhibitors 7-NI, L-NAME, and L-NOARG in staircase test. Arch Med Res 33:265-268
    • (2002) Arch Med Res , vol.33 , pp. 265-268
    • Pokk, P.1    Vali, M.2
  • 89
    • 0036139809 scopus 로고    scopus 로고
    • The effects of the nitric oxide synthase inhibitors on the behaviour of small-platform-stressed mice in the plus-maze test
    • Pokk P, Vali M (2002b) The effects of the nitric oxide synthase inhibitors on the behaviour of small-platform-stressed mice in the plus-maze test. Prog Neuropsychopharmacol Biol Psychiatry 26:241-247
    • (2002) Prog Neuropsychopharmacol Biol Psychiatry , vol.26 , pp. 241-247
    • Pokk, P.1    Vali, M.2
  • 91
    • 0025821074 scopus 로고
    • Tetranucleotide repeat polymorphism at the human tyrosine hydroxylase gene (TH)
    • Polymeropoulos MH, Xiao H, Rath DS, Merril CR (1991) Tetranucleotide repeat polymorphism at the human tyrosine hydroxylase gene (TH). Nucl Acids Res 19:3753
    • (1991) Nucl Acids Res , vol.19 , pp. 3753
    • Polymeropoulos, M.H.1    Xiao, H.2    Rath, D.S.3    Merril, C.R.4
  • 92
    • 0034844055 scopus 로고    scopus 로고
    • 4 receptor activation inhibits presynaptically glutamatergic neurotransmission in the rat supraoptic nucleus
    • 4 receptor activation inhibits presynaptically glutamatergic neurotransmission in the rat supraoptic nucleus. J Neurophysiol 86:1149-1155
    • (2001) J Neurophysiol , vol.86 , pp. 1149-1155
    • Price, C.J.1    Pittman, Q.J.2
  • 98
    • 0031711343 scopus 로고    scopus 로고
    • A functional polymorphism in the monoamine oxidase A gene promoter
    • Sabol SZ, Hu S, Hamer D (1998) A functional polymorphism in the monoamine oxidase A gene promoter. Hum Genet 103:273-279
    • (1998) Hum Genet , vol.103 , pp. 273-279
    • Sabol, S.Z.1    Hu, S.2    Hamer, D.3
  • 100
    • 0034656961 scopus 로고    scopus 로고
    • Patterns of symptom improvement during antidepressant treatment of delusional depression
    • Serretti A, Lattuada E, Zanardi R, Franchini L, Smeraldi E (2000) Patterns of symptom improvement during antidepressant treatment of delusional depression. Psychiatry Res 94:185-190
    • (2000) Psychiatry Res , vol.94 , pp. 185-190
    • Serretti, A.1    Lattuada, E.2    Zanardi, R.3    Franchini, L.4    Smeraldi, E.5
  • 103
    • 0034885170 scopus 로고    scopus 로고
    • Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity
    • Serretti A, Zanardi R, Rossini D, Cusin C, Lilli R, Smeraldi E (2001c) Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity. Mol Psychiatry 6:586-592
    • (2001) Mol Psychiatry , vol.6 , pp. 586-592
    • Serretti, A.1    Zanardi, R.2    Rossini, D.3    Cusin, C.4    Lilli, R.5    Smeraldi, E.6
  • 107
    • 0035450481 scopus 로고    scopus 로고
    • Identification and functional characterization of alpha(2)-adrenoceptor polymorphisms
    • Small KM, Liggett SB (2001) Identification and functional characterization of alpha(2)-adrenoceptor polymorphisms. Trends Pharmacol Sci 22:471-477
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 471-477
    • Small, K.M.1    Liggett, S.B.2
  • 108
    • 0031736757 scopus 로고    scopus 로고
    • Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
    • Smeraldi E, Zanardi R, Benedetti F, Dibella D, Perez J, Catalano M (1998) Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol Psychiatry 3:508-511
    • (1998) Mol Psychiatry , vol.3 , pp. 508-511
    • Smeraldi, E.1    Zanardi, R.2    Benedetti, F.3    Dibella, D.4    Perez, J.5    Catalano, M.6
  • 110
    • 0026033949 scopus 로고
    • Assignment of a serotonin 5HT-2 receptor gene (HTR2) to human chromosome 13q14-q21 and mouse chromosome 14
    • Sparkes RS, Lan N, Klisak I, Mohandas T, Diep A, Kojis T, Heinzmann C, Shih JC (1991) Assignment of a serotonin 5HT-2 receptor gene (HTR2) to human chromosome 13q14-q21 and mouse chromosome 14. Genomics 9:461-465
    • (1991) Genomics , vol.9 , pp. 461-465
    • Sparkes, R.S.1    Lan, N.2    Klisak, I.3    Mohandas, T.4    Diep, A.5    Kojis, T.6    Heinzmann, C.7    Shih, J.C.8
  • 112
    • 0031917424 scopus 로고    scopus 로고
    • Basic psychopharmacology of antidepressants, part 1: Antidepressants have seven distinct mechanisms of action
    • Stahl SM (1998) Basic psychopharmacology of antidepressants, part 1: Antidepressants have seven distinct mechanisms of action. J Clin Psychiatry 59:5-14
    • (1998) J Clin Psychiatry , vol.59 , pp. 5-14
    • Stahl, S.M.1
  • 113
    • 0034966799 scopus 로고    scopus 로고
    • Pharmacogenetics: A new diagnostic tool in the management of antidepressive drug therapy
    • Steimer W, Muller B, Leucht S, Kissling W (2001) Pharmacogenetics: a new diagnostic tool in the management of antidepressive drug therapy. Clin Chim Acta 308:33-41
    • (2001) Clin Chim Acta , vol.308 , pp. 33-41
    • Steimer, W.1    Muller, B.2    Leucht, S.3    Kissling, W.4
  • 114
    • 0029838815 scopus 로고    scopus 로고
    • Systematic search for variation in the human norepinephrine transporter gene: Identification of five naturally occurring missense mutations and study of association with major psychiatric disorders
    • Stober G, Nothen MM, Porzgen P, Bruss M, Bonisch H, Knapp M, Beckmann H, Propping P (1996) Systematic search for variation in the human norepinephrine transporter gene: identification of five naturally occurring missense mutations and study of association with major psychiatric disorders. Am J Med Genet 67:523-532
    • (1996) Am J Med Genet , vol.67 , pp. 523-532
    • Stober, G.1    Nothen, M.M.2    Porzgen, P.3    Bruss, M.4    Bonisch, H.5    Knapp, M.6    Beckmann, H.7    Propping, P.8
  • 115
    • 0033020993 scopus 로고    scopus 로고
    • Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers
    • Szabo ST, de Montigny C, Blier P (1999) Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers. Br J Pharmacol 126:568-571
    • (1999) Br J Pharmacol , vol.126 , pp. 568-571
    • Szabo, S.T.1    De Montigny, C.2    Blier, P.3
  • 117
    • 0037043746 scopus 로고    scopus 로고
    • Norepinephrine transporter and alpha(2c) adrenoceptor allelic variants and personality factors
    • Tsai SJ, Wang YC, Hong CJ (2002) Norepinephrine transporter and alpha(2c) adrenoceptor allelic variants and personality factors. Am J Med Genet 114:649-651
    • (2002) Am J Med Genet , vol.114 , pp. 649-651
    • Tsai, S.J.1    Wang, Y.C.2    Hong, C.J.3
  • 118
    • 0142219372 scopus 로고    scopus 로고
    • Association study of a brain-derived neurotrophic-factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response
    • Tsai SJ, Cheng CY, Yu YW, Chen TJ, Hong CJ (2003) Association study of a brain-derived neurotrophic-factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response. Am J Med Genet 123B:19-22
    • (2003) Am J Med Genet , vol.123 B , pp. 19-22
    • Tsai, S.J.1    Cheng, C.Y.2    Yu, Y.W.3    Chen, T.J.4    Hong, C.J.5
  • 120
    • 0033952456 scopus 로고    scopus 로고
    • Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption
    • Uhr M, Steckler T, Yassouridis A, Holsboer F (2000) Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption. Neuropsychopharmacology 22:380-387
    • (2000) Neuropsychopharmacology , vol.22 , pp. 380-387
    • Uhr, M.1    Steckler, T.2    Yassouridis, A.3    Holsboer, F.4
  • 121
    • 0036629763 scopus 로고    scopus 로고
    • Treatment of cycling female rats with fluoxetine induces desensitization of hypothalamic 5-HT(1A) receptors with no change in 5-HT(2A) receptors
    • Van de Kar LD, Raap DK, Battaglia G, Muma NA, Garcia F, DonCarlos LL (2002) Treatment of cycling female rats with fluoxetine induces desensitization of hypothalamic 5-HT(1A) receptors with no change in 5-HT(2A) receptors. Neuropharmacology 43:45-54
    • (2002) Neuropharmacology , vol.43 , pp. 45-54
    • Van De Kar, L.D.1    Raap, D.K.2    Battaglia, G.3    Muma, N.A.4    Garcia, F.5    DonCarlos, L.L.6
  • 122
    • 0034730476 scopus 로고    scopus 로고
    • Antidepressants: Past, present and future
    • Vetulani J, Nalepa I (2000) Antidepressants: past, present and future. Eur J Pharmacol 405:351-363
    • (2000) Eur J Pharmacol , vol.405 , pp. 351-363
    • Vetulani, J.1    Nalepa, I.2
  • 123
    • 0030838355 scopus 로고    scopus 로고
    • 7-Nitroindazole, a nitric oxide synthase inhibitor, has anxiolytic-like properties in exploratory models of anxiety
    • Volke V, Soosaar A, Koks S, Bourin M, Mannisto PT, Vasar E (1997) 7-Nitroindazole, a nitric oxide synthase inhibitor, has anxiolytic-like properties in exploratory models of anxiety. Psychopharmacology 131:399-405
    • (1997) Psychopharmacology , vol.131 , pp. 399-405
    • Volke, V.1    Soosaar, A.2    Koks, S.3    Bourin, M.4    Mannisto, P.T.5    Vasar, E.6
  • 124
    • 0141922899 scopus 로고    scopus 로고
    • A unique central tryptophan hydroxylase isoform
    • Walther DJ, Bader M (2003) A unique central tryptophan hydroxylase isoform. Biochem Pharmacol 66:1673-1680
    • (2003) Biochem Pharmacol , vol.66 , pp. 1673-1680
    • Walther, D.J.1    Bader, M.2
  • 126
    • 0030592471 scopus 로고    scopus 로고
    • A study of the relationship between the DBH activity in serum and a MspI polymorphic site in intron 9 of the human DBH gene in schizophrenia
    • Wei J, Ramchand CN, Hemmings GP (1996) A study of the relationship between the DBH activity in serum and a MspI polymorphic site in intron 9 of the human DBH gene in schizophrenia. Schizophr Res 22:77-80
    • (1996) Schizophr Res , vol.22 , pp. 77-80
    • Wei, J.1    Ramchand, C.N.2    Hemmings, G.P.3
  • 127
    • 0036501648 scopus 로고    scopus 로고
    • A polymorphism in the dopamine beta-hydroxylase gene is associated with "paranoid ideation" in patients with major depression
    • Wood JG, Joyce PR, Miller AL, Mulder RT, Kennedy MA (2002) A polymorphism in the dopamine beta-hydroxylase gene is associated with "paranoid ideation" in patients with major depression. Biol Psychiatry 51:365-369
    • (2002) Biol Psychiatry , vol.51 , pp. 365-369
    • Wood, J.G.1    Joyce, P.R.2    Miller, A.L.3    Mulder, R.T.4    Kennedy, M.A.5
  • 129
    • 0034764508 scopus 로고    scopus 로고
    • Association study of the 5-HT(6) receptor polymorphism (C267T) and symptomatology and antidepressant response in major depressive disorders
    • Wu WH, Huo SJ, Cheng CY, Hong CJ, Tsai SJ (2001) Association study of the 5-HT(6) receptor polymorphism (C267T) and symptomatology and antidepressant response in major depressive disorders. Neuropsychobiology 44:172-175
    • (2001) Neuropsychobiology , vol.44 , pp. 172-175
    • Wu, W.H.1    Huo, S.J.2    Cheng, C.Y.3    Hong, C.J.4    Tsai, S.J.5
  • 131
    • 0028180867 scopus 로고
    • Localization of the cDNA for an alpha 1-adrenergic receptor subtype (ADRA1D) to chromosome band 20p13
    • Yang-Feng TL, Han H, Lomasney JW, Caron MG (1994) Localization of the cDNA for an alpha 1-adrenergic receptor subtype (ADRA1D) to chromosome band 20p13. Cytogenet Cell Genet 66:170-171
    • (1994) Cytogenet Cell Genet , vol.66 , pp. 170-171
    • Yang-Feng, T.L.1    Han, H.2    Lomasney, J.W.3    Caron, M.G.4
  • 132
    • 0034110759 scopus 로고    scopus 로고
    • Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats
    • Yildiz F, Erden BF, Ulak G, Utkan T, Gacar N (2000) Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats. Psychopharmacology 149:41-44
    • (2000) Psychopharmacology , vol.149 , pp. 41-44
    • Yildiz, F.1    Erden, B.F.2    Ulak, G.3    Utkan, T.4    Gacar, N.5
  • 135
    • 0036931893 scopus 로고    scopus 로고
    • Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders
    • Yu YW, Tsai SJ, Chen TJ, Lin CH, Hong CJ (2002) Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders. Mol Psychiatry 7:1115-1119
    • (2002) Mol Psychiatry , vol.7 , pp. 1115-1119
    • Yu, Y.W.1    Tsai, S.J.2    Chen, T.J.3    Lin, C.H.4    Hong, C.J.5
  • 136
    • 0042844775 scopus 로고    scopus 로고
    • Association study of the interleukin-1beta (C-511T) genetic polymorphism with major depressive disorder, associated symptomatology, and antidepressant response
    • Yu YW, Chen TJ, Hong CJ, Chen HM, Tsai SJ (2003a) Association study of the interleukin-1beta (C-511T) genetic polymorphism with major depressive disorder, associated symptomatology, and antidepressant response. Neuropsychopharmacology 28:1182-1185
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1182-1185
    • Yu, Y.W.1    Chen, T.J.2    Hong, C.J.3    Chen, H.M.4    Tsai, S.J.5
  • 137
    • 0038655593 scopus 로고    scopus 로고
    • Association analysis for neuronal nitric oxide synthase gene polymorphism with major depression and fluoxetine response
    • Yu YW, Chen TJ, Wang YC, Liou YJ, Hong CJ, Tsai SJ (2003b) Association analysis for neuronal nitric oxide synthase gene polymorphism with major depression and fluoxetine response. Neuropsychobiology 47:137-140
    • (2003) Neuropsychobiology , vol.47 , pp. 137-140
    • Yu, Y.W.1    Chen, T.J.2    Wang, Y.C.3    Liou, Y.J.4    Hong, C.J.5    Tsai, S.J.6
  • 139
    • 0033984363 scopus 로고    scopus 로고
    • Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of serotonin transporter gene
    • Zanardi R, Benedetti F, DiBella D, Catalano M, Smeraldi E (2000) Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of serotonin transporter gene. J Clin Psychopharmacol 20:105-107
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 105-107
    • Zanardi, R.1    Benedetti, F.2    DiBella, D.3    Catalano, M.4    Smeraldi, E.5
  • 140
    • 0035450812 scopus 로고    scopus 로고
    • Factors affecting fluvoxamine antidepressant activity: Influence of pindolol and 5-HTTLPR in delusional and nondelusional depression
    • Zanardi R, Serretti A, Rossini D, Franchini L, Cusin C, Lattuada E, Dotoli D, Smeraldi E (2001) Factors affecting fluvoxamine antidepressant activity: influence of pindolol and 5-HTTLPR in delusional and nondelusional depression. Biol Psychiatry 50:323-330
    • (2001) Biol Psychiatry , vol.50 , pp. 323-330
    • Zanardi, R.1    Serretti, A.2    Rossini, D.3    Franchini, L.4    Cusin, C.5    Lattuada, E.6    Dotoli, D.7    Smeraldi, E.8
  • 141
    • 0034995406 scopus 로고    scopus 로고
    • Association between depressive behavior and absence of serotonin-dopamine interaction in the nucleus accumbens
    • Zangen A, Nakash R, Overstreet DH, Yadid G (2001) Association between depressive behavior and absence of serotonin-dopamine interaction in the nucleus accumbens. Psychopharmacology 155:434-439
    • (2001) Psychopharmacology , vol.155 , pp. 434-439
    • Zangen, A.1    Nakash, R.2    Overstreet, D.H.3    Yadid, G.4
  • 142
    • 0034721952 scopus 로고    scopus 로고
    • GABA(B) receptor mechanism and imipramine-induced antinociception in ligated and non-ligated mice
    • Zarrindast M, Valizadeh S, Sahebgharani M (2000) GABA(B) receptor mechanism and imipramine-induced antinociception in ligated and non-ligated mice. Eur J Pharmacol 407:65-72
    • (2000) Eur J Pharmacol , vol.407 , pp. 65-72
    • Zarrindast, M.1    Valizadeh, S.2    Sahebgharani, M.3
  • 143
    • 0034717626 scopus 로고    scopus 로고
    • Evidence for an association between a G-protein beta3-gene variant with depression and response to antidepressant treatment
    • Zill P, Baghai TC, Zwanzger P, Schule C, Minov C, Riedel M, Neumeier K, Rupprecht R, Bondy B (2000) Evidence for an association between a G-protein beta3-gene variant with depression and response to antidepressant treatment. Neuroreport 11:1893-1897
    • (2000) Neuroreport , vol.11 , pp. 1893-1897
    • Zill, P.1    Baghai, T.C.2    Zwanzger, P.3    Schule, C.4    Minov, C.5    Riedel, M.6    Neumeier, K.7    Rupprecht, R.8    Bondy, B.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.