Association analysis for neuronal nitric oxide synthase gene polymorphism with major depression and fluoxetine response

Neuropsychobiology

Volumn 47, Issue 3, 2003, Pages 137-140

  Yu, Younger W Y ^a   Chen, Tai Jui ^b   Wang, Ying Chieh ^c   Liou, Ying Jay ^c   Hong, Chen Jee ^d,e   Tsai, Shih Jen ^d,e  

^a Yu's Psychiatric Clinic   (Taiwan)

^b KAI SUAN PSYCHIATRIC HOSPITAL   (Taiwan)

^c YULI VETERANS HOSPITAL   (Taiwan)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Major depressive disorders; Nitric oxide synthase; Polymorphism; Selective serotonin reuptake inhibitors

Indexed keywords

FLUOXETINE; NITRIC OXIDE SYNTHASE;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; POPULATION RESEARCH; PRIORITY JOURNAL; SEXUAL DYSFUNCTION; TREATMENT OUTCOME;

ADULT; ANTIPSYCHOTIC AGENTS; DEPRESSIVE DISORDER, MAJOR; FEMALE; FLUOXETINE; GENE EXPRESSION; GENE FREQUENCY; GENOTYPE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC;

EID: 0038655593     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000070582     Document Type: Article

References (17)

1. Karatinos J, Rosse RB, Deutsch SI: The nitric oxide pathway: Potential implications for treatment of neuropsychiatric disorders. Clin Neuropharmacol 1995;18:482-499.
2. Ogden JE, Moore PK: Inhibition of nitric oxide synthase - Potential for a novel class of therapeutic agent? Trends Biotechnol 1995;13:70-78.
3. Finkel MS, Laghrissi-Thode F, Pollock BG, Rong J: Paroxetine is a novel nitric oxide synthase inhibitor. Psychopharmacol Bull 1996;32:653-658.
4. Harkin AJ, Bruce KH, Craft B, Paul IA: Nitric oxide synthase inhibitors have antidepressant-like properties in mice. 1. Acute treatments are active in the forced swim test. Eur J Pharmacol 1999;372:207-213.
5. da Silva GD, Matteussi AS, dos Santos AR, Calixto JB, Rodrigues AL: Evidence for dual effects of nitric oxide in the forced swimming test and in the tail suspension test in mice. Neuroreport 2000;11:3699-3702.
6. Yildiz F, Erden BF, Ulak G, Utkan T, Gacar N: Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats. Psychopharmacology 2000;149:41-44.
7. Karolewicz B, Bruce KH, Lee B, Paul IA: Nitric oxide synthase inhibitors have antidepressant-like properties in mice. 2. Chronic treatment results in downregulation of cortical beta-adrenoceptors. Eur J Pharmacol 1999;372:215-220.
8. Suzuki E, Yagi G, Nakaki T, Kanba S, Asai M: Elevated plasma nitrate levels in depressive states. J Affect Disord 2001;63:221-224.
9. Kishimoto J, Spurr N, Liao M, Lizhi L, Emson P, Xu W: Localization of brain nitric oxide synthase (NOS) to human chromosome 12. Genomics 1992;14:802-804.
10. Shinkai T, Ohmori O, Hori H, Nakamura J: Allelic association of the neuronal nitric oxide synthase (NOS1) gene with schizophrenia. Mol Psychiatry 2002;7:560-563.
11. Yu YWY, Tsai SJ, Chen TJ, Lin CH, Hong CJ: Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders. Mol Psychiatry 2002;7:1115-1119.
12. Hamilton M: Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967;6:278-296.
13. Grasemann H, Yandava CN, Drazen JM: Neuronal NO synthase (NOS1) is a major candidate gene for asthma. Clin Exp Allergy 1999;29(suppl 4):39-41.
14. Briley M, Moret C: Neurobiological mechanisms involved in antidepressant therapies. Clin Neuropharmacol 1993;16:387-400.
15. Montejo-Gonzalez AL, Llorca G, Izquierdo JA, Ledesma A, Bousono M, Calcedo A, Carrasco JL, Ciudad J, Daniel E, De la Gandara J, Derecho J, Franco M, Gomez MJ, Macias JA, Martin T, Perez V, Sanchez JM, Sanchez S, Vicens E: SSRI-induced sexual dysfunction: Fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patients. J Sex Marital Ther 1997;23:176-194.
16. Escrig A, Gonzalez-Mora JL, Mas M: Nitric oxide release in penile corpora cavernosa in a rat model of erection. J Physiol 1999;516:261-269.
17. Angulo J, Peiro C, Sanchez-Ferrer CF, Gabancho S, Cuevas P, Gupta S, Saenz de Tejada I: Differential effects of serotonin reuptake inhibitors on erectile responses, NO-production, and neuronal NO synthase expression in rat corpus cavernosum tissue. Br J Pharmacol 2001;134:1190-1194.