Screening ABCG1, the human homologue of the drosophila white gene, for polymorphisms and association with bipolar affective disorder

Molecular Psychiatry

Volumn 6, Issue 6, 2001, Pages 671-677

  Kirov, G ^a   Lowry, C A ^b   Stephens, M ^a   Oldfield, S ^b   O'Donovan, M C ^a   Lightman, S L ^b   Owen, M J ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Human white; Linkage disequilibrium; Microsatellite; SNP; Tdt; Tryptophan

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER G1; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; AFFECTIVE NEUROSIS; ALLELE; ARTICLE; CONTROLLED STUDY; DROSOPHILA; EXON; FAMILY STUDY; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC SCREENING; HAPLOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTRON; MAJOR CLINICAL STUDY; MANIC DEPRESSIVE PSYCHOSIS; PANIC; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VARIABLE NUMBER OF TANDEM REPEAT;

3' UNTRANSLATED REGIONS; 5' FLANKING REGION; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIPOLAR DISORDER; DNA PRIMERS; DNA, COMPLEMENTARY; DROSOPHILA; DROSOPHILA PROTEINS; EXONS; EYE PROTEINS; GENETIC SCREENING; GENOTYPE; HUMANS; INSECT PROTEINS; INTRONS; LINKAGE DISEQUILIBRIUM; MICROSATELLITE REPEATS; POLYMORPHISM, SINGLE NUCLEOTIDE; TRYPTOPHAN;

EID: 0034751703     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000899     Document Type: Article

References (36)

1. Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster. Implications for structure-function relationships
2. Genetic and functional analysis of tryptophan transport in Malpighian tubules of Drosophila
3. Serotonin release varies with brain tryptophan levels
4. Stress-induced release of 5-HT in the hippocampus and its dependence on increased tryptophan availability: An in vivo electrochemical study
5. ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport
6. Polymorphisms of the human homologue of the Drosophila white gene are associated with mood and panic disorders
7. Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3
8. The DNA sequence of human chromosome 21. The chromosome 21 mapping and sequencing consortium
9. Genomic organization and characterization of the promoter of the human ATP-binding cassette transporter-G1 (ABCG1) gene(1)
10. A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3
11. Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q
12. Two-locus admixture linkage analysis of bipolar and unipolar affective disorder supports the presence of susceptibility loci on chromosomes 11p15 and 21q22
13. A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus
14. Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5
15. Bipolar disorder and the serotonin transporter gene: A family-based association study
16. DNA mutation detection using denaturing high-performance liquid chromatography (DHPLC)
17. Optimal temperature selection for mutation detection by denaturing HPLC and comparison to single-stranded conformation polymorphism and heteroduplex analysis
18. Tandem repeats finder: A program to analyze DNA sequences
19. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
20. An extended transmission disequilibrium test (TDT) for multiallele market loci
21. Descent graphs in pedigree analysis: Applications to haplotyping, location scores, and marker sharing statistics
22. The interaction of selection and linkage. I. General considerations; heterotic models
23. Pooled genotyping of microsatellite markers in parent-offspring trios
24. Genomewide transmission/disequilibrium testing - Consideration of the genotypic relative risks at disease loci
25. Genomewide transmission/disequilibrium testing: A correction
26. Tryptophan hydroxylase gene and manic-depressive illness
27. Suicidal behaviour, affective disorders and a polymorphism in the ABCG1 gene
28. How neutral polymorphisms reflect functional ones. Effects of allele frequency disparities in candidate gene association studies
29. Prospects for whole-genome linkage disequilibrium mapping of common disease genes
30. SNPing away at complex diseases: Analysis of single-nucleotide polymorphisms around APOE in Alzheimer Disease
31. Variation in the Interleukin 4-receptor α gene confers susceptibility to asthma and atopy in ethnically diverse populations
32. Single nucleotide polymorphism and linkage disequilibrium within the TCR α/β locus
33. Localisation of psoriasis-susceptibility locus PSOR1 to a 60-kb interval telomeric to HLA-C
34. Linkage disequilibrium and the search for complex disease genes