메뉴 건너뛰기




Volumn 59, Issue SUPPL.4, 1998, Pages 5-14

Basic psychopharmacology of antidepressants, Part 1: Antidepressants have seven distinct mechanisms of action

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; MIRTAZAPINE; NEFAZODONE; NORADRENALIN; SEROTONIN; VENLAFAXINE;

EID: 0031917424     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (263)

References (107)
  • 3
    • 0001095253 scopus 로고
    • Indoleamines: The role of serotonin in clinical disorders
    • Bloom FE, Kupfer DJ, eds. New York, NY: Raven Press
    • Heninger GR. Indoleamines: the role of serotonin in clinical disorders. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress. New York, NY: Raven Press; 1995:471-482
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 471-482
    • Heninger, G.R.1
  • 4
    • 85012427534 scopus 로고
    • The monoamine hypothesis of depression: The case for serotonin
    • Brown SL, van Praag HM, eds. New York, NY: Brunner/ Mazel
    • Brown SL, Bleich A, van Praag HM. The monoamine hypothesis of depression: the case for serotonin. In: Brown SL, van Praag HM, eds. The Role of Serotonin in Psychiatric Disorders. New York, NY: Brunner/ Mazel; 1991:91-128
    • (1991) The Role of Serotonin in Psychiatric Disorders , pp. 91-128
    • Brown, S.L.1    Bleich, A.2    Van Praag, H.M.3
  • 5
    • 0000587671 scopus 로고
    • The serotonin hypothesis of major depression
    • Bloom FE, Kupfer DJ, eds. New York, NY: Raven Press
    • Maes M, Meltzer HY. The serotonin hypothesis of major depression. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress. New York, NY: Raven Press; 1995:933-944
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 6
    • 0000264756 scopus 로고
    • The catecholamine hypothesis of affective disorders: A review of supporting evidence
    • Schildkraut JJ. The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am J Psychiatry 1965;122:509-522
    • (1965) Am J Psychiatry , vol.122 , pp. 509-522
    • Schildkraut, J.J.1
  • 7
    • 0000358207 scopus 로고
    • Norepinephrine and serotonin transporters: Molecular targets of antidepressant drugs
    • Bloom FE, Kupfer DJ, eds. New York, NY: Raven Press
    • Barker EL, Blakely RD. Norepinephrine and serotonin transporters: molecular targets of antidepressant drugs. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress. New York, NY: Raven Press; 1995:321-334
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 321-334
    • Barker, E.L.1    Blakely, R.D.2
  • 8
    • 0030032338 scopus 로고    scopus 로고
    • Initiation and adaptation: A paradigm for understanding psychotropic drug action
    • Hyman SE, Nestler EJ. Initiation and adaptation: a paradigm for understanding psychotropic drug action. Am J Psychiatry 1996;153:151-162
    • (1996) Am J Psychiatry , vol.153 , pp. 151-162
    • Hyman, S.E.1    Nestler, E.J.2
  • 9
    • 0026456891 scopus 로고
    • Electrophysiological studies on the effects of long term reuptake inhibition on the function of 5HT neurons
    • de Montigny C, Pineyo G, Chaput Y, et al. Electrophysiological studies on the effects of long term reuptake inhibition on the function of 5HT neurons. Clin Neuropharmacol 1992;115(suppl 1A):440A-441A
    • (1992) Clin Neuropharmacol , vol.115 , Issue.SUPPL. 1A
    • De Montigny, C.1    Pineyo, G.2    Chaput, Y.3
  • 10
    • 0019469314 scopus 로고
    • Receptor sensitivity and the mechanism of action of antidepressant treatment: Implications for the etiology and therapy of depression
    • Charney DS, Menkes DB, Heninger GR. Receptor sensitivity and the mechanism of action of antidepressant treatment: implications for the etiology and therapy of depression. Arch Gen Psychiatry 1981;38:1160-1180
    • (1981) Arch Gen Psychiatry , vol.38 , pp. 1160-1180
    • Charney, D.S.1    Menkes, D.B.2    Heninger, G.R.3
  • 11
    • 0002019131 scopus 로고
    • The receptor sensitivity hypothesis of antidepressant action: A review of antidepressant effects on serotonin function
    • Brown SL, van Praag HM, eds. New York, NY: Brunner/Mazel
    • Charney DS, Delgade PL, Price LH, et al. The receptor sensitivity hypothesis of antidepressant action: a review of antidepressant effects on serotonin function. In: Brown SL, van Praag HM, eds. The Role of Serotonin in Psychiatric Disorders. New York, NY: Brunner/Mazel; 1991:27-56
    • (1991) The Role of Serotonin in Psychiatric Disorders , pp. 27-56
    • Charney, D.S.1    Delgade, P.L.2    Price, L.H.3
  • 13
    • 0020353647 scopus 로고
    • Pharmacology of antidepressants in use in the United States
    • Richelson E. Pharmacology of antidepressants in use in the United States. J Clin Psychiatry 1982;43:(11, sec.2):4-11
    • (1982) J Clin Psychiatry , vol.43 , Issue.11 SEC.2 , pp. 4-11
    • Richelson, E.1
  • 15
    • 0023606602 scopus 로고
    • Modifications of the serotonin system by antidepressant treatment: Implications for the therapeutic response in major depression
    • Blier P, de Montigny C, Chaput Y. Modifications of the serotonin system by antidepressant treatment: implications for the therapeutic response in major depression. J Clin Psychopharmacol 1987;7:24S-35S
    • (1987) J Clin Psychopharmacol , vol.7
    • Blier, P.1    De Montigny, C.2    Chaput, Y.3
  • 16
    • 0028287265 scopus 로고
    • Current advances and trends in the treatment of depression
    • Blier P, de Montigny C. Current advances and trends in the treatment of depression. Trends Pharmacol Sci 1994;15:220-224
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 220-224
    • Blier, P.1    De Montigny, C.2
  • 17
    • 0027508045 scopus 로고
    • Differential properties of pre- And post-synaptic 5-hydroxytryptamine 1A receptors, I: Effect of spiperone
    • Blier P, Lista A, de Montigny C. Differential properties of pre-and post-synaptic 5-hydroxytryptamine 1A receptors, I: effect of spiperone. J Pharmacol ExpTher 1993;265:7-15
    • (1993) J Pharmacol ExpTher , vol.265 , pp. 7-15
    • Blier, P.1    Lista, A.2    De Montigny, C.3
  • 18
    • 0027494515 scopus 로고
    • Differential properties of pre- And postsynaptic 5-hydroxytryptamine 1A receptors. II: Effect of pertussis and cholera toxins
    • Blier P, Lista A, de Montigny C. Differential properties of pre-and postsynaptic 5-hydroxytryptamine 1A receptors. II: effect of pertussis and cholera toxins. J Pharmacol Exp Ther 1993;265:16-23
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 16-23
    • Blier, P.1    Lista, A.2    De Montigny, C.3
  • 19
    • 0022454164 scopus 로고
    • Effects of a selective 5HT reuptake blocker, citalopram, on the sensitivity of 5HT autoreceptors: Electrophysiological studies in the rat brain
    • Chaput Y, de Montigny C, Blier P. Effects of a selective 5HT reuptake blocker, citalopram, on the sensitivity of 5HT autoreceptors: electrophysiological studies in the rat brain. Naunyn Schmiedebergs Arch Pharmacol 1986;333:342-348
    • (1986) Naunyn Schmiedebergs Arch Pharmacol , vol.333 , pp. 342-348
    • Chaput, Y.1    De Montigny, C.2    Blier, P.3
  • 20
    • 0026348807 scopus 로고
    • Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments: An in vivo electrophysiological study in the rat
    • Chaput Y, de Montigny C, Blier P. Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments: an in vivo electrophysiological study in the rat. Neuropsychopharmacology 1991;5:19-29
    • (1991) Neuropsychopharmacology , vol.5 , pp. 19-29
    • Chaput, Y.1    De Montigny, C.2    Blier, P.3
  • 21
    • 0026456891 scopus 로고
    • Electrophysiological studies on the effects of long term reuptake inhibition of the function of 5HT neurons
    • de Montigny C, Pineyro G, Chaput Y, et al. Electrophysiological studies on the effects of long term reuptake inhibition of the function of 5HT neurons. Clin Neuropharmacol 1992;15(suppl 1A):440A-441A
    • (1992) Clin Neuropharmacol , vol.15 , Issue.SUPPL. 1A
    • De Montigny, C.1    Pineyro, G.2    Chaput, Y.3
  • 22
    • 0028214689 scopus 로고
    • Increase in extracellular serotonin produced by uptake inhibitors is enhanced after chronic treatment with fluoxetine
    • Rutter JJ, Gundiah C, Auerbach SB. Increase in extracellular serotonin produced by uptake inhibitors is enhanced after chronic treatment with fluoxetine. Neurosci Lett 1994;171:183-186
    • (1994) Neurosci Lett , vol.171 , pp. 183-186
    • Rutter, J.J.1    Gundiah, C.2    Auerbach, S.B.3
  • 23
    • 0002482728 scopus 로고
    • Presynaptic regulation of extracellular serotonin concentrations in brain
    • Takada A, Curzon G, eds. Amsterdam, The Netherlands: Elsevier Science
    • Wong DT, Bymaster FP, Engleman EA. Presynaptic regulation of extracellular serotonin concentrations in brain. In: Takada A, Curzon G, eds. Serotonin in the Central Nervous System and Periphery. Amsterdam, The Netherlands: Elsevier Science; 1995:3-13
    • (1995) Serotonin in the Central Nervous System and Periphery , pp. 3-13
    • Wong, D.T.1    Bymaster, F.P.2    Engleman, E.A.3
  • 24
    • 0026566906 scopus 로고
    • Fluvoxamine preferentially increases extracellular 5HT in the raphe nuclei: An in vivo microdialysis study
    • Bel N, Artigas F. Fluvoxamine preferentially increases extracellular 5HT in the raphe nuclei: an in vivo microdialysis study. Eur J Pharmacol 1992;229: 101-103
    • (1992) Eur J Pharmacol , vol.229 , pp. 101-103
    • Bel, N.1    Artigas, F.2
  • 25
    • 0027421854 scopus 로고
    • Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei
    • Bel N, Artigas F. Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei. Synapse 1993;15: 243-245
    • (1993) Synapse , vol.15 , pp. 243-245
    • Bel, N.1    Artigas, F.2
  • 26
    • 0344710450 scopus 로고    scopus 로고
    • Mechanism of action of serotonin selective reuptake inhibitors: Serotonin receptors and pathways mediate therapeutic effects and side effects
    • In press
    • Stahl SM. Mechanism of action of serotonin selective reuptake inhibitors: serotonin receptors and pathways mediate therapeutic effects and side effects. J Affect Disord. In press
    • J Affect Disord.
    • Stahl, S.M.1
  • 27
    • 0028102141 scopus 로고
    • Is serotonin receptor down regulation linked to the mechanism of action of antidepressant drugs?
    • Stahl SM. Is serotonin receptor down regulation linked to the mechanism of action of antidepressant drugs? Psychopharmacol Bull 1994;30: 39-43
    • (1994) Psychopharmacol Bull , vol.30 , pp. 39-43
    • Stahl, S.M.1
  • 28
    • 0019122846 scopus 로고
    • Long term antidepressant treatment lowers spiroperidol labelled serotonin receptor binding
    • Peroutka SJ, Snyder SH. Long term antidepressant treatment lowers spiroperidol labelled serotonin receptor binding. Science 1980;210:88-90
    • (1980) Science , vol.210 , pp. 88-90
    • Peroutka, S.J.1    Snyder, S.H.2
  • 29
    • 0002777541 scopus 로고
    • Electophysiology of serotonin receptor subtypes and signal transduction pathways
    • Bloom FE, Kupfer DJ, eds. New York, NY: Raven Press
    • Aghajanian GK. Electophysiology of serotonin receptor subtypes and signal transduction pathways. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress. New York, NY: Raven Press; 1995:451-460
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 451-460
    • Aghajanian, G.K.1
  • 31
    • 0026213117 scopus 로고
    • Serotonin receptor subtypes: Implications for psychopharmacology
    • Cowen PJ. Serotonin receptor subtypes: implications for psychopharmacology. Br J Psychiatry 1991;159(suppl 12):7-14
    • (1991) Br J Psychiatry , vol.159 , Issue.12 SUPPL. , pp. 7-14
    • Cowen, P.J.1
  • 32
    • 0028208756 scopus 로고
    • Beyond the serotonin reuptake inhibitors: Rationales for the development of new serotonergic agents
    • Dubovsky SL. Beyond the serotonin reuptake inhibitors: rationales for the development of new serotonergic agents. J Clin Psychiatry 1994;55(2, suppl):34-44
    • (1994) J Clin Psychiatry , vol.55 , Issue.2 SUPPL. , pp. 34-44
    • Dubovsky, S.L.1
  • 34
    • 0002556006 scopus 로고
    • Serotonin and behavior: A general hypothesis
    • Bloom FE, Kupfer DJ, eds. New York, NY: Raven Press
    • Jacobs BL, Fornal CA. Serotonin and behavior: a general hypothesis. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress. New York, NY: Raven Press; 1995;461-470
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 461-470
    • Jacobs, B.L.1    Fornal, C.A.2
  • 35
    • 0029045946 scopus 로고
    • Behavioral pharmacology of serotonin receptor subtypes: Hypotheses for clinical applications of selective serotonin ligands
    • Keppel Hesselink JM, Sambunaris A. Behavioral pharmacology of serotonin receptor subtypes: hypotheses for clinical applications of selective serotonin ligands. International Review of Psychiatry 1995;7:41-54
    • (1995) International Review of Psychiatry , vol.7 , pp. 41-54
    • Keppel Hesselink, J.M.1    Sambunaris, A.2
  • 36
    • 0029076547 scopus 로고
    • Biochemical pharmacology of serotonin receptor subtypes: Hypothesis for clinical applications of selective serotonin ligands
    • Kunovac JL, Stahl SM. Biochemical pharmacology of serotonin receptor subtypes: hypothesis for clinical applications of selective serotonin ligands. International Review of Psychiatry 1995;7:55-68
    • (1995) International Review of Psychiatry , vol.7 , pp. 55-68
    • Kunovac, J.L.1    Stahl, S.M.2
  • 37
    • 0001782388 scopus 로고
    • 5HT2 receptors: Location, pharmacological, pathological and physiological role
    • Langer SZ, Brunello N, Racagni G, et al, eds. Basel, Switzerland: Karger
    • Leysen JE. 5HT2 receptors: location, pharmacological, pathological and physiological role. In: Langer SZ, Brunello N, Racagni G, et al, eds. Serotonin receptor subtypes: pharmacological significance and clinical implications. Basel, Switzerland: Karger; 1992:31-44
    • (1992) Serotonin Receptor Subtypes: Pharmacological Significance and Clinical Implications , pp. 31-44
    • Leysen, J.E.1
  • 38
    • 0026657470 scopus 로고
    • Subtypes of serotonin receptors: Biochemical changes and pharmacological consequences
    • Leonard BE. Subtypes of serotonin receptors: biochemical changes and pharmacological consequences. Int Clin Psychopharmacol 1992;7:13-21
    • (1992) Int Clin Psychopharmacol , vol.7 , pp. 13-21
    • Leonard, B.E.1
  • 39
    • 0026725877 scopus 로고
    • Neurochemical alterations of serotonergic neuronal systems in depression
    • Risch SC, Nemeroff CB. Neurochemical alterations of serotonergic neuronal systems in depression. J Clin Psychiatry 1992;53(10, suppl):3-7
    • (1992) J Clin Psychiatry , vol.53 , Issue.10 SUPPL. , pp. 3-7
    • Risch, S.C.1    Nemeroff, C.B.2
  • 41
    • 0002820647 scopus 로고
    • Molecular biology of serotonin receptors: A basis for understanding and addressing brain function
    • Bloom FE, Kupfer DJ, eds. New York, NY: Raven Press
    • Shih JC, Chen K J-S, Gallaher TK. Molecular biology of serotonin receptors: a basis for understanding and addressing brain function. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress; New York, NY: Raven Press: 1995:407-414
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 407-414
    • Shih, J.C.1    Chen, K.J.-S.2    Gallaher, T.K.3
  • 42
    • 0002540923 scopus 로고
    • Anatomy, cell biology, and plasticity of the serotonergic system: Neuropsychopharmacological implications for the actions of psychotropic drugs
    • Bloom FE, Kupfer DJ, eds. New York, NY: Raven Press
    • Arzmitia EF, Whitaker-Arzmitia PM. Anatomy, cell biology, and plasticity of the serotonergic system: neuropsychopharmacological implications for the actions of psychotropic drugs. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress. New York, NY: Raven Press; 1995:443-450
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 443-450
    • Arzmitia, E.F.1    Whitaker-Arzmitia, P.M.2
  • 43
    • 0025816189 scopus 로고
    • Autoradiographic analysis of serotonin 1A receptor binding in the human brain postmortem: Effects of age and alcohol
    • Dillon KA. Autoradiographic analysis of serotonin 1A receptor binding in the human brain postmortem: effects of age and alcohol. Brain Res 1991; 554:56-64
    • (1991) Brain Res , vol.554 , pp. 56-64
    • Dillon, K.A.1
  • 44
    • 0002440944 scopus 로고
    • Biochemical anatomy: Insights into the cell biology and pharmacology of neurotransmitter systems in the brain
    • Schatzberg A, Nemeroff CB, eds. Washington, DC: American Psychiatric Press
    • Mansour A, Chalmers DT, Fox CA, et al. Biochemical anatomy: insights into the cell biology and pharmacology of neurotransmitter systems in the brain. In: Schatzberg A, Nemeroff CB, eds. Textbook of Psychopharmacology. Washington, DC: American Psychiatric Press; 1995:45-64
    • (1995) Textbook of Psychopharmacology , pp. 45-64
    • Mansour, A.1    Chalmers, D.T.2    Fox, C.A.3
  • 46
    • 0013516618 scopus 로고
    • An overview of serotonin neurochemistry and neuroanatomy
    • Sandler ML, Coppen A, Harnett S, eds. Oxford, England: Oxford University Press
    • Murphy DL. An overview of serotonin neurochemistry and neuroanatomy. In: Sandler ML, Coppen A, Harnett S, eds. 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas. Oxford, England: Oxford University Press; 1991:23-36
    • (1991) 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas , pp. 23-36
    • Murphy, D.L.1
  • 47
    • 0027772849 scopus 로고
    • Serotonin receptor heterogeneity and subsystem complexity: Implications for clinical neuropsychopharmacology
    • Lesch KP, Aulakh CS, Murphy DL. Serotonin receptor heterogeneity and subsystem complexity: implications for clinical neuropsychopharmacology. Neurology and Psychiatry Brain Research 1993;1:163-172
    • (1993) Neurology and Psychiatry Brain Research , vol.1 , pp. 163-172
    • Kp, L.1    Aulakh, C.S.2    Murphy, D.L.3
  • 48
    • 0022346190 scopus 로고
    • Quantitative autoradiographic mapping of serotonin receptors in the brain. I: Serotonin 1 receptors
    • Pazos A, Palacios JM. Quantitative autoradiographic mapping of serotonin receptors in the brain. I: serotonin 1 receptors. Brain Res 1985;346: 205-230
    • (1985) Brain Res , vol.346 , pp. 205-230
    • Pazos, A.1    Palacios, J.M.2
  • 49
    • 0022401097 scopus 로고
    • Quantitative autoradiographic mapping of serotonin receptors in the brain, II: Serotonin 2 receptors
    • Pazos A, Palacios JM. Quantitative autoradiographic mapping of serotonin receptors in the brain, II: serotonin 2 receptors. Brain Res 1985;346: 231-249
    • (1985) Brain Res , vol.346 , pp. 231-249
    • Pazos, A.1    Palacios, J.M.2
  • 50
    • 0026559955 scopus 로고
    • Pharmacological and physiochemical properties of pre- Versus postsynaptic 5-hydroxy-tryptamine 1A receptor binding sites in the rat brain: Quantitative autoradiographic study
    • Radja F, Daval G, Hamon M, et al. Pharmacological and physiochemical properties of pre-versus postsynaptic 5-hydroxy-tryptamine 1A receptor binding sites in the rat brain: quantitative autoradiographic study. J Neurochem 1992;58:1338-1346
    • (1992) J Neurochem , vol.58 , pp. 1338-1346
    • Radja, F.1    Daval, G.2    Hamon, M.3
  • 52
    • 0028786861 scopus 로고
    • Alteration of serotonin release in the guinea pig orbito-frontal cortex by selective serotonin reuptake inhibitors: Relevance to treatment of obsessive compulsive disorder
    • El Mansari M, Bouchard C, Blier P. Alteration of serotonin release in the guinea pig orbito-frontal cortex by selective serotonin reuptake inhibitors: relevance to treatment of obsessive compulsive disorder. Neuropsychopharmacology 1995;13:117-127
    • (1995) Neuropsychopharmacology , vol.13 , pp. 117-127
    • El Mansari, M.1    Bouchard, C.2    Blier, P.3
  • 53
    • 0025728334 scopus 로고
    • Differential effects of clomipramine given locally or systemically on extracellular 5HT in raphe nuclei and frontal cortex: An in vivo microdialysis study
    • Adell A, Artigas F. Differential effects of clomipramine given locally or systemically on extracellular 5HT in raphe nuclei and frontal cortex: an in vivo microdialysis study. Naunyn Schmiedebergs Arch Pharmacol 1991;343:237-244
    • (1991) Naunyn Schmiedebergs Arch Pharmacol , vol.343 , pp. 237-244
    • Adell, A.1    Artigas, F.2
  • 54
    • 0027163303 scopus 로고
    • 5HT1A receptor antagonists in combination therapy: 5HT and antidepressants: new views from microdialysis studies
    • Artigas F. 5HT1A receptor antagonists in combination therapy: 5HT and antidepressants: new views from microdialysis studies. Trends Pharmacol Sci 1993;14:262-270
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 262-270
    • Artigas, F.1
  • 55
    • 0024508732 scopus 로고
    • Reduction of prefrontal cortex glucose metabolism common to three types of depression
    • Baxter LR, Schwartz JM, Phelps ME. Reduction of prefrontal cortex glucose metabolism common to three types of depression. Arch Gen Psychiatry 1989;46:243-250
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 243-250
    • Baxter, L.R.1    Schwartz, J.M.2    Phelps, M.E.3
  • 56
    • 0023066678 scopus 로고
    • Development of the noradrenergic, serotonergic and dopaminergic innervation of neocortex
    • Foote SL, Morrison JH. Development of the noradrenergic, serotonergic and dopaminergic innervation of neocortex. Curr Top Dev Biol 1987;21: 391-423
    • (1987) Curr Top Dev Biol , vol.21 , pp. 391-423
    • Foote, S.L.1    Morrison, J.H.2
  • 57
    • 0028305977 scopus 로고
    • Short-term fluoxetine treatment alters monoamine levels and turnover in discrete brain nuclei
    • Frankfurt M, McKittrick CR, Luine VN. Short-term fluoxetine treatment alters monoamine levels and turnover in discrete brain nuclei. Brain Res 1994;650:127-132
    • (1994) Brain Res , vol.650 , pp. 127-132
    • Frankfurt, M.1    McKittrick, C.R.2    Luine, V.N.3
  • 58
    • 0028283115 scopus 로고
    • Mini-review: Uptake inhibitors increase extracellular serotonin concentration measured by brain microdialysis
    • Fuller R. Mini-review: uptake inhibitors increase extracellular serotonin concentration measured by brain microdialysis. Life Sci 1994;55:163-167
    • (1994) Life Sci , vol.55 , pp. 163-167
    • Fuller, R.1
  • 59
    • 0026654169 scopus 로고
    • Citalopram's ability to increase the extracellular concentrations of serotonin in the dorsal raphe prevents the drug's effect in the frontal cortex
    • Invernizzi R, Belli S, Samanin R. Citalopram's ability to increase the extracellular concentrations of serotonin in the dorsal raphe prevents the drug's effect in the frontal cortex. Brain Res 1992;584:322-324
    • (1992) Brain Res , vol.584 , pp. 322-324
    • Invernizzi, R.1    Belli, S.2    Samanin, R.3
  • 60
    • 0027946258 scopus 로고
    • In vivo biogenic amine efflux in medial prefrontal cortex with imipramine, fluoxetine, and fluvoxamine
    • Jordan S, Dramer GL, Zukas PK, et al. In vivo biogenic amine efflux in medial prefrontal cortex with imipramine, fluoxetine, and fluvoxamine. Synapse 1994;18:294-297
    • (1994) Synapse , vol.18 , pp. 294-297
    • Jordan, S.1    Dramer, G.L.2    Zukas, P.K.3
  • 61
  • 62
    • 0022645522 scopus 로고
    • Noradrenergic and serotonergic innervation of cortical and thalamic visual structures in old and new world monkeys
    • Morrison JH, Foote SL. Noradrenergic and serotonergic innervation of cortical and thalamic visual structures in old and new world monkeys. J Comp Neurol 1986;243:117-138
    • (1986) J Comp Neurol , vol.243 , pp. 117-138
    • Morrison, J.H.1    Foote, S.L.2
  • 63
    • 0000218766 scopus 로고
    • Regional and laminar patterns of monoamine innervation of primate neocortex
    • Sandler M, Dahlstrom A, Belmaker RH, eds. New York, NY: Alan Liss
    • Morrison JH, Foote SL, Lewis DA, et al. Regional and laminar patterns of monoamine innervation of primate neocortex. In: Sandler M, Dahlstrom A, Belmaker RH, eds. Progress in Catecholamine Research, part B: Central Aspects. New York, NY: Alan Liss: 1988:193-198
    • (1988) Progress in Catecholamine Research, Part B: Central Aspects , pp. 193-198
    • Morrison, J.H.1    Foote, S.L.2    Lewis, D.A.3
  • 64
    • 0027442597 scopus 로고
    • Acute uptake inhibition increases extracellular serotonin in the rat forebrain
    • Rutter JJ, Auerbach SB. Acute uptake inhibition increases extracellular serotonin in the rat forebrain. J Pharmacol Exp Ther 1993;265:1319-1324
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1319-1324
    • Rutter, J.J.1    Auerbach, S.B.2
  • 65
    • 0030048176 scopus 로고    scopus 로고
    • Demonstration in vivo of reduced serotonin responsivity in the brain of untreated depressed patients
    • Mann JJ, Malone KM, Diehl DJ, et al. Demonstration in vivo of reduced serotonin responsivity in the brain of untreated depressed patients. Am J Psychiatry 1996;153:174-182
    • (1996) Am J Psychiatry , vol.153 , pp. 174-182
    • Mann, J.J.1    Malone, K.M.2    Diehl, D.J.3
  • 66
    • 0026779811 scopus 로고
    • Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive compulsive disorder
    • Baxter LR, Schwartz JM, Bergman KS, et al. Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive compulsive disorder. Arch Gen Psychiatry 1992;49:681-689
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 681-689
    • Baxter, L.R.1    Schwartz, J.M.2    Bergman, K.S.3
  • 67
    • 0001770245 scopus 로고
    • Neuroimaging in obsessive compulsive disorder: Seeking the mediating neuroanatomy
    • Jenike MA, Baer L, Minichiello WE, eds. Chicago, Ill: Year Book Medical Publishers
    • Baxter LR, Schwartz JM, Guze BH, et al. Neuroimaging in obsessive compulsive disorder: seeking the mediating neuroanatomy. In: Jenike MA, Baer L, Minichiello WE, eds. Obsessive Compulsive Disorders: Theory and Management. 2nd ed. Chicago, Ill: Year Book Medical Publishers; 1990:167-188
    • (1990) Obsessive Compulsive Disorders: Theory and Management. 2nd Ed. , pp. 167-188
    • Baxter, L.R.1    Schwartz, J.M.2    Guze, B.H.3
  • 68
    • 0000329420 scopus 로고
    • A neuroanatomical hypothesis for panic disorder
    • Gorman J, Liebowicz MR, Fyer AJ. A neuroanatomical hypothesis for panic disorder. Am J Psychiatry 1989;150:1480-1484
    • (1989) Am J Psychiatry , vol.150 , pp. 1480-1484
    • Gorman, J.1    Liebowicz, M.R.2    Fyer, A.J.3
  • 69
    • 0025045260 scopus 로고
    • Cerebral glucose metabolic differences in patients with panic disorder
    • Nordahl TE, Semple WE, Gross M. Cerebral glucose metabolic differences in patients with panic disorder. Neuropsychopharmacology 1990;3: 261-272
    • (1990) Neuropsychopharmacology , vol.3 , pp. 261-272
    • Nordahl, T.E.1    Semple, W.E.2    Gross, M.3
  • 70
    • 0013556650 scopus 로고
    • Biology of eating disorders
    • Schatzberg A, Nemeroff CB, eds. Washington, DC: American Psychiatric Press
    • Casper RC. Biology of eating disorders. In: Schatzberg A, Nemeroff CB, eds. Textbook of Psychopharmacology. Washington, DC: American Psychiatric Press; 1995:557-574
    • (1995) Textbook of Psychopharmacology , pp. 557-574
    • Casper, R.C.1
  • 71
    • 0013553487 scopus 로고
    • 5-hydroxytryptamine in the control of feeding and its possible implications for appetite disturbance
    • Sandler ML, Coppen A, Harnett S. eds. Oxford, England: Oxford University Press
    • Curzon G. 5-hydroxytryptamine in the control of feeding and its possible implications for appetite disturbance. In: Sandler ML, Coppen A, Harnett S. eds. 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas. Oxford, England: Oxford University Press; 1991:279-302
    • (1991) 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas , pp. 279-302
    • Curzon, G.1
  • 72
    • 0027173523 scopus 로고
    • The hypophagic effect of restraint stress in rats can be mediated by 5HT2 receptors in the parventricular nucleus of the hypothalamus
    • Grigsnaschi G, Mantelli B, Samanin R. The hypophagic effect of restraint stress in rats can be mediated by 5HT2 receptors in the parventricular nucleus of the hypothalamus. Neurosci Lett 1993;152:1036
    • (1993) Neurosci Lett , vol.152 , pp. 1036
    • Grigsnaschi, G.1    Mantelli, B.2    Samanin, R.3
  • 73
    • 0026389012 scopus 로고
    • Effect of serotonin reuptake inhibition by fluoxetine on body weight and spontaneous food choice in obesity
    • Piji H, Koppeschaar HP, Willekens FL. Effect of serotonin reuptake inhibition by fluoxetine on body weight and spontaneous food choice in obesity. Int J Obes Relat Metab Disord 1991;15:237-242
    • (1991) Int J Obes Relat Metab Disord , vol.15 , pp. 237-242
    • Piji, H.1    Koppeschaar, H.P.2    Willekens, F.L.3
  • 74
    • 0001832143 scopus 로고
    • Psychopharmacology of anorexia nervosa, bulimia nervosa and binge eating
    • Bloom FE, Kupfer DJ, eds. New York, NY: Raven Press
    • Walsh BT, Devlin MJ. Psychopharmacology of anorexia nervosa, bulimia nervosa and binge eating. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology: The Fourth Generation of Progress. New York, NY: Raven Press; 1995:1581-1590
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 1581-1590
    • Walsh, B.T.1    Devlin, M.J.2
  • 75
    • 0030776757 scopus 로고    scopus 로고
    • Are two antidepressant mechanisms better than one?
    • Stahl SM. Are two antidepressant mechanisms better than one? J Clin Psychiatry 1997;58:339-341
    • (1997) J Clin Psychiatry , vol.58 , pp. 339-341
    • Stahl, S.M.1
  • 76
    • 0001882279 scopus 로고    scopus 로고
    • The effects of antidepressants on human sexuality: Diagnosis and management update 1996
    • Balon R. The effects of antidepressants on human sexuality: diagnosis and management update 1996. Primary Psychiatry 1997;4:32-48
    • (1997) Primary Psychiatry , vol.4 , pp. 32-48
    • Balon, R.1
  • 77
    • 0003322726 scopus 로고
    • Sexual dysfunction associated with the drug treatment of psychiatric disorders
    • Stein DJ, Hollander E. Sexual dysfunction associated with the drug treatment of psychiatric disorders. CNS Drugs 1994;2:78-86
    • (1994) CNS Drugs , vol.2 , pp. 78-86
    • Stein, D.J.1    Hollander, E.2
  • 78
    • 0002767839 scopus 로고
    • Treatment-emergent sexual dysfunction in affective disorder: A review and management strategies
    • Segraves RT. Treatment-emergent sexual dysfunction in affective disorder: a review and management strategies. J Clin Psychiatry Monograph 1993; 11(1):57-60
    • (1993) J Clin Psychiatry Monograph , vol.11 , Issue.1 , pp. 57-60
    • Segraves, R.T.1
  • 79
    • 0024594291 scopus 로고
    • Interactions between dopamine and 5HT3 receptors suggest new treatments for psychosis and drug addiction
    • Trickelbank MD. Interactions between dopamine and 5HT3 receptors suggest new treatments for psychosis and drug addiction. Trends Pharmacol Sci 1989;10:127-129
    • (1989) Trends Pharmacol Sci , vol.10 , pp. 127-129
    • Trickelbank, M.D.1
  • 80
    • 0025572228 scopus 로고
    • 5HT2 antagonist ritanserin in neuroleptic induced parkinsonism: A double blind comparison with orphenadrine and placebo
    • Bersani G, Grispini A, Marini S, et al. 5HT2 antagonist ritanserin in neuroleptic induced parkinsonism: a double blind comparison with orphenadrine and placebo. Clin Neuropharmacol 1990;13:500-506
    • (1990) Clin Neuropharmacol , vol.13 , pp. 500-506
    • Bersani, G.1    Grispini, A.2    Marini, S.3
  • 81
    • 0026569201 scopus 로고
    • Effect of fluoxetine on serotonin and dopamine concentration in microdialysis fluid from rat striatum
    • Perry KW, Fuller RW. Effect of fluoxetine on serotonin and dopamine concentration in microdialysis fluid from rat striatum. Life Sci 1992;50: 1583-1590
    • (1992) Life Sci , vol.50 , pp. 1583-1590
    • Perry, K.W.1    Fuller, R.W.2
  • 82
    • 0000118432 scopus 로고
    • Antipsychotic medications
    • Schatzberg A, Nemeroff CB, eds. Washington. DC: American Psychiatric Press
    • Marder SR, Van Putten T. Antipsychotic medications. In: Schatzberg A, Nemeroff CB, eds. Textbook of Psychopharmacology. Washington. DC: American Psychiatric Press; 1995;247-262
    • (1995) Textbook of Psychopharmacology , pp. 247-262
    • Marder, S.R.1    Van Putten, T.2
  • 84
    • 0025923015 scopus 로고
    • Are 5HT2 antagonists endowed with anxiolytic properties in rodents?
    • Stutzmann JM, Eon B, Darche F, et al. Are 5HT2 antagonists endowed with anxiolytic properties in rodents? Neurosci Lett 1991;128:4-8
    • (1991) Neurosci Lett , vol.128 , pp. 4-8
    • Stutzmann, J.M.1    Eon, B.2    Darche, F.3
  • 86
    • 0030201336 scopus 로고    scopus 로고
    • Ipsapirone, a 5HT1a agonist, suppresses REM sleep equally in depressed patients and normal controls
    • Gillin JC, Sohn WJ, Stahl SM, et al. Ipsapirone, a 5HT1A agonist, suppresses REM sleep equally in depressed patients and normal controls. Neuropsychopharmacology. 1996;15:109-115
    • (1996) Neuropsychopharmacology , vol.15 , pp. 109-115
    • Gillin, J.C.1    Sohn, W.J.2    Stahl, S.M.3
  • 87
    • 0029666455 scopus 로고    scopus 로고
    • The 5HT1a agonist ipsapirone enhances EEG slow wave activity in human sleep and produces a power spectrum analysis similar to 5HT2 blockade
    • Seifritz E, Moore P, Trachsel L, et al. The 5HT1A agonist ipsapirone enhances EEG slow wave activity in human sleep and produces a power spectrum analysis similar to 5HT2 blockade. Neurosci Lett 1996;209:41-44
    • (1996) Neurosci Lett , vol.209 , pp. 41-44
    • Seifritz, E.1    Moore, P.2    Trachsel, L.3
  • 88
    • 0030157914 scopus 로고    scopus 로고
    • Fluoxetine-induced sleep disturbance in depressed patients
    • Dorsey CM, Lukas SE, Cunningham SL. Fluoxetine-induced sleep disturbance in depressed patients. Neuropharmacology 1996;14:437-442
    • (1996) Neuropharmacology , vol.14 , pp. 437-442
    • Dorsey, C.M.1    Lukas, S.E.2    Cunningham, S.L.3
  • 89
    • 0029890287 scopus 로고    scopus 로고
    • The effects of paroxetine and nefazodone on sleep: A placebo controlled trial
    • Berl
    • Sharpley AL, Williamson DJ, Attenburrow MEJ, et al. The effects of paroxetine and nefazodone on sleep: a placebo controlled trial. Psychopharmacology (Berl) 1996;126:50-54
    • (1996) Psychopharmacology , vol.126 , pp. 50-54
    • Sharpley, A.L.1    Williamson, D.J.2    Attenburrow, M.E.J.3
  • 90
    • 0026020205 scopus 로고
    • Clinical evaluation of 5HT3 receptor antagonists as anti-emetics
    • Bunce K, Tyers M, Beranek P. Clinical evaluation of 5HT3 receptor antagonists as anti-emetics. Trends Pharmacol Sci 1991;12:46-48
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 46-48
    • Bunce, K.1    Tyers, M.2    Beranek, P.3
  • 92
    • 0027478474 scopus 로고
    • Ondansetron plus metopimazine compared with ondansetron alone in patients receiving moderately emetogenic chemotherapy
    • Herrstedt J, Sigsaard T, Boesgarrd M. Ondansetron plus metopimazine compared with ondansetron alone in patients receiving moderately emetogenic chemotherapy. N Engl J Med 1993;328:1076-1080
    • (1993) N Engl J Med , vol.328 , pp. 1076-1080
    • Herrstedt, J.1    Sigsaard, T.2    Boesgarrd, M.3
  • 93
    • 0027461853 scopus 로고
    • Ondansetron compared with dexamethasone and metclopramide as antiemetics in the chemotherapy of breast cancer with cyclophosphamide, methotrexate, and fluorouracil
    • Levitt M, Warr D, Yelle L. Ondansetron compared with dexamethasone and metclopramide as antiemetics in the chemotherapy of breast cancer with cyclophosphamide, methotrexate, and fluorouracil. N Engl J Med 1993;328:1081-1084
    • (1993) N Engl J Med , vol.328 , pp. 1081-1084
    • Levitt, M.1    Warr, D.2    Yelle, L.3
  • 94
    • 0027960056 scopus 로고
    • Evidence that the acute behavioral and electrophysiological effects of bupropion (Wellbutrin) are mediated by a noradrenergic mechanism
    • Cooper BR, Wang CM, Cox RF, et al Evidence that the acute behavioral and electrophysiological effects of bupropion (Wellbutrin) are mediated by a noradrenergic mechanism. Neuropharmacology 1994;11:133-141
    • (1994) Neuropharmacology , vol.11 , pp. 133-141
    • Cooper, B.R.1    Wang, C.M.2    Cox, R.F.3
  • 97
    • 0023926156 scopus 로고
    • Clinical and neuropsychological effects of the novel antidepressant bupropion
    • Clay TH, Gualtieri T, Evans RW, et al. Clinical and neuropsychological effects of the novel antidepressant bupropion. Psychopharmacol Bull 1988; 24:143-148
    • (1988) Psychopharmacol Bull , vol.24 , pp. 143-148
    • Clay, T.H.1    Gualtieri, T.2    Evans, R.W.3
  • 98
    • 0031940879 scopus 로고    scopus 로고
    • Bupropion sustained release and smoking cessation
    • Goldstein MG. Bupropion sustained release and smoking cessation. J Clin Psychiatry 1998;59(suppl 4):66-72
    • (1998) J Clin Psychiatry , vol.59 , Issue.4 SUPPL. , pp. 66-72
    • Goldstein, M.G.1
  • 99
    • 0344301932 scopus 로고    scopus 로고
    • Bupropion sustained release: Side effect profile
    • Settle EC Jr. Bupropion sustained release: side effect profile. J Clin Psychiatry. 1998;59(suppl 4):32-36
    • (1998) J Clin Psychiatry. , vol.59 , Issue.4 SUPPL. , pp. 32-36
    • Settle Jr., E.C.1
  • 100
    • 0022879288 scopus 로고
    • Antidepressant biochemical profile of the novel bicyclic compound WY-455,030 (venlafaxine), an ethyl cyclohexanol derivative
    • Muth EA, Haskins JT, Moyer JA, et al. Antidepressant biochemical profile of the novel bicyclic compound WY-455,030 (venlafaxine), an ethyl cyclohexanol derivative. Biochem Pharmacol 1986;35:4493-4497
    • (1986) Biochem Pharmacol , vol.35 , pp. 4493-4497
    • Muth, E.A.1    Haskins, J.T.2    Moyer, J.A.3
  • 101
    • 0027475571 scopus 로고
    • Blockade by newly-developed antidepressants of biogenic amine uptake into rat brain synaptosomes
    • Bolden-Watson C, Richelson E. Blockade by newly-developed antidepressants of biogenic amine uptake into rat brain synaptosomes. Life Sci 1993;52:1023-1029
    • (1993) Life Sci , vol.52 , pp. 1023-1029
    • Bolden-Watson, C.1    Richelson, E.2
  • 102
    • 0013106373 scopus 로고    scopus 로고
    • Remeron (mirtazapine): A novel antidepressant that disinhibits serotonin and norepinephrine by alpha-2 antagonism
    • Stahl SM. Remeron (mirtazapine): a novel antidepressant that disinhibits serotonin and norepinephrine by alpha-2 antagonism. Psychiatric Annals 1997;27:14-16
    • (1997) Psychiatric Annals , vol.27 , pp. 14-16
    • Stahl, S.M.1
  • 103
    • 21444445937 scopus 로고    scopus 로고
    • Remeron (mirtazapine): Designing specific serotonergic actions
    • Stahl SM. Remeron (mirtazapine): designing specific serotonergic actions. Psychiatric Annals 1997;27:138-144
    • (1997) Psychiatric Annals , vol.27 , pp. 138-144
    • Stahl, S.M.1
  • 104
    • 0029610098 scopus 로고
    • Noradrenergic modulation of central serotonergic neurotransmission: Acute and long-term actions of mirtazapine
    • Haddjeri N, Blier P, de Montigny C. Noradrenergic modulation of central serotonergic neurotransmission: acute and long-term actions of mirtazapine. Int Clin Psychopharmacol 1995;10(suppl 4):11-17
    • (1995) Int Clin Psychopharmacol , vol.10 , Issue.4 SUPPL. , pp. 11-17
    • Haddjeri, N.1    Blier, P.2    De Montigny, C.3
  • 105
    • 0029046487 scopus 로고
    • The alpha-2 selective adrenoceptor antagonist Org 3770 (mirtazapine; Remeron) enhances noradrenergic and serotonergic transmission
    • DeBoer T, Guist GSF, Berendsen HHG. The alpha-2 selective adrenoceptor antagonist Org 3770 (mirtazapine; Remeron) enhances noradrenergic and serotonergic transmission. Human Psychopharmacology 1995;10: S107-S118
    • (1995) Human Psychopharmacology , vol.10
    • DeBoer, T.1    Guist, G.S.F.2    Berendsen, H.H.G.3
  • 106
    • 0031029632 scopus 로고    scopus 로고
    • Mirtazapine: An antidepressant with selective alpha-2 adrenoceptor antagonist effects
    • Stimmel GL, Dopheide JA, Stahl SM. Mirtazapine: an antidepressant with selective alpha-2 adrenoceptor antagonist effects. Pharmacotherapy 1997;17:10-21
    • (1997) Pharmacotherapy , vol.17 , pp. 10-21
    • Stimmel, G.L.1    Dopheide, J.A.2    Stahl, S.M.3
  • 107
    • 0030809048 scopus 로고    scopus 로고
    • Meta-analysis of randomized, double-blind, placebo-controlled, efficacy and safety studies of mirtazapine versus amitriptyline in major depression
    • Stahl SM, Zivkov M, Reimitz PE, et al. Meta-analysis of randomized, double-blind, placebo-controlled, efficacy and safety studies of mirtazapine versus amitriptyline in major depression. Acta Psychiatr Scand 1997;96(suppl 391):22-30
    • (1997) Acta Psychiatr Scand , vol.96 , Issue.391 SUPPL. , pp. 22-30
    • Stahl, S.M.1    Zivkov, M.2    Reimitz, P.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.