Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain: A quantitative in situ hybridization study

Journal of Molecular Neuroscience

Volumn 10, Issue 3, 1998, Pages 219-233

  Boyer, Pierre Alain ^a   Skolnick, Phil ^b   Fossom, Linda H ^c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Antidepressants; Citalopram; Imipramine; NMDA

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; IMIPRAMINE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN SUBUNIT;

ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN REGION; DRUG EFFECT; DRUG SCREENING; FRONTAL CORTEX; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR BINDING;

ANIMALIA;

EID: 0031751159     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02761776     Document Type: Article

References (51)

1. Bovetto S., Boyer P. A., Skolnick P., and Fossom L. H. (1997) Chronic administration of a glycine partial agonist alters the expression of NMDA receptor subunit mRNAs. J. Pharmacol. Exp. Ther. 283, 1503-1508.
2. Brunello N., Langer S. Z., Perez J., and Racagni G. (1995) Current understanding of the mechanism of action of classic and newer antidepressant drugs. Depression 2, 119-126.
3. Caldecott-Hazard S., Morgan D. G., DeLeon-Jones F., Overstreet D. H., and Janowsky D. (1991) Clinical and biochemical aspects of depressive disorders: II Transmitter receptor theories. Synapse 9, 251-301.
4. Drevets W. C., Videen T. O., Price J. L., Preskorn S. H., Carmichael S. T., and Raichle M. E. (1992) A functional anatomical study of unipolar depression. J. Neurosci. 12, 3628-3641.
5. Duman R. S., Nibuya M., and Vaidya V. A. (1997) A role for CREB in antidepressant action, in Antidepressants: New Pharmacological Strategies (Skolnick P., ed.), Humana, Totowa, NJ, pp. 173-194.
6. Fink M. (1979) Convulsive Therapy: Theory and Practice. Raven, New York.
7. Heninger G. and Charney D. (1987) Mechanism of action of antidepressant treatments: implications for the etiology and treatment of depressive disorders, in Psychopharmacology: the Third Generation of Progress (Meltzer H., ed.), Raven, New York, p. 535.
8. Heninger G. R., Delgado P. L., and Charney D. S. (1996) The revised monoamine theory of depression: A modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans. Pharmacopsychiatry 29, 2-11.
9. Hjorth S. (1993) Serotonin 5HT1A autoreceptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: a microdialysis study. J. Neurochem. 60, 776-779.
10. Huang N., Layer R. T., and Skolnick P. (1997) Is an adaptation of N-methyl-D-aspartate (NMDA) receptors an obligatory step in antidepressant action? in Antidepressants: New Pharmacological Strategies (Skolnick P., ed.), Humana, Totowa, NJ, pp. 125-143.
11. Ishii T., Moriyoshi K., Sugihara,. H., Sakurada K., Kadotani H., Yokoi M., et al. (1993) Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. J. Biol. Chem. 268, 2836-2843.
12. Kraus J. E., Nadler J. V., and McNamara J. O. (1996) Regulation of alternative splicing of NMDAR1 in the kindling model. Mol. Brain Res. 41, 97-104.
13. Kutsuwada T., Kashiwabuchi N., Mori H., Sakimura K., Kushiya E., Araki K., et al. (1992) Molecular diversity of the NMDA receptor channel. Nature 358, 36-41.
14. Laurie D. J. and Seeburg P. H. (1994) Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition. Eur. J. Pharm. 268, 335-345.
15. Layer R. T., Popik P., Nowak G., Paul I. A., Trullas R., and Skolnick P. (1998) A unified theory of antidepressant action: evidence for adaptation of the N-methyl-D-aspartate (NMDA) receptor complex following chronic antidepressant treatments, in Ion Channel Pharmacology (Soria B. and Cena V., eds.), Oxford University Press, London, pp. 438-456.
16. Lin Y. J., Bovetto S., Carver J. M., and Giordano T. (1996) The cloning of the human NR2-C NMDA glutamate receptor and its expression in the central nervous system and periphery. Mol. Brain Res. 43, 57-64.
17. Lynch D. R., Anegawa N. J., Verdoorn T., and Pritchett D. B. (1994) N-methyl-D-aspartate receptors: different subunit requirements for binding of glutamate antagonists, glycine antagonists, and channel-blocking agents. Mol. Pharmacol. 45, 540-545.
18. Maccecchini M. L. (1995) Partial agonism and neuroprotection, in Ischemic Stroke: Recent Advances in Understanding & Therapy (Grotta J., Miller L. P., and Buchan A. M., eds.), International Business Communications, Southboro, pp. 140-168.
19. Meshul C. K., Bunker G. L., Mason J. N., Allen C., and Janowsky A. (1996) Effects of subchronic clozapine and haloperidol on striatal glutamatergic synapses. J. Neurochem. 67, 1965-1973.
20. Milne R. J. and Goa K. L. (1991) Citalopram: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness. Drugs 41, 450-477.
21. Monyer H., Sprengel R., Schoepfer R., Herb A., Higuchi M., Lomeli H., et al. (1992) Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256, 1217-1221.
22. Mori H. and Mishina M. (1995) Structure and function of the NMDA receptor channel. Neuropharmacology 34, 1219-1237.
23. Moriyoshi K., Masu M., Ishii T., Shigemoto R., Mizuno N., and Nakanishi S. (1991) Molecular cloning and characterization of the rat NMDA receptor. Nature 354, 31-36.
24. Moryl E., Dansyz W., and Quach G. (1993) Potential antidepressive properties of amantadine, memantine and bifelamine. Pharmacol. Toxicol. 72, 394-397.
25. Nakanishi S. (1992) Molecular diversity of glutamate receptors and implications for brain function. Science 258, 597-603.
26. Naylor P., Stewart C. A., Wright S. R., Pearson R. C. A., and Reid I. C. (1996) Repeated ECS induces GluR1 mRNA but not NMDAR1A-G mRNA in the rat hippocampus. Mol. Brain Res. 35, 349-353.
27. Nibuya M., Nestler E. J., and Duman R. S. (1996) Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J. Neurosci. 16, 2365-2372.
28. Nowak G., Trullas R., Layer R. T., Skolnick P., and Paul I. A. (1993) Adaptative changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-amino-cyclopropanecarboxylic acid. J. Pharm. Exp. Ther. 265, 1380-1386.
29. Nowak G., Li Y., and Paul I. A. (1996) Adaptation of cortical but not hippocampal NMDA receptors after chronic citalopram treatment. Eur. J. Pharmacol. 295, 74-85.
30. Oretti R. G., Spurlock G., Buckland P. R., and McGuffin P. (1994) Lack of effect of antipsychotic and antidepressant drugs on glutamate receptor mRNA levels in rat brains. Neurosci. Lett. 177, 39-43.
31. Oswald I., Brezinova V., and Dunleavy D. L. F. (1972) On the slowness of action of tricyclic antidepressant drugs. Br. J. Psychiatr. 120, 673-677.
32. Papp M. and Moryl E. (1993) Similar effect of chronic treatment with imipramine and the NMDA antagonist CGP 37849 and MK 801 in a chronic mild stress model of depression in rats. Eur. J. Neuropsychopharmacol. 3, 348,349.
33. Papp M. and Moryl E. (1994) Antidepressant activity of non-competitive and competitive NMDA receptor antagonists in a chronic mild stress model of depression. Eur. J. Pharmacol. 263, 1-7.
34. Papp M. and Moryl E. (1996) Antidepressant-like effects of 1-aminocyclopropanecarboxylic acid and D-cycloserine in an animal model of depression. Eur. J. Pharmacol. 316, 145-151.
35. Paul I. A., Nowak G., Layer R. T., Popik P., and Skolnick P. (1994) Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressants treatments. J. Pharmacol. Exp. Ther. 269, 95-102.
36. Paul S. M., Wu X., Liang Y., and Ginns E. I. (1997) Molecular strategies to novel antidepressant discovery, in Antidepressants: New Pharmacological Strategies (Skolnick P., ed.), Humana, Totowa, NJ, pp. 235-250.
37. Rigby M., Le Bourdelles B., Heavens R. P., Kelly S., Smith D., Butler A., et al. (1996) The messenger RNAs for the N-methyl-D-aspartate receptor subunits show region-specific expression of different subunit composition in the human brain. Neuroscience 73, 429-447.
38. Rosenberg C. D., Damsbo N., Fuglum E., Jacobsen L. V., and Horsgard S. (1994) Citalopram and imipramine in the treatment of depressive patients in general practice. A nordic multicentre clinical study. Int. Clin. Psychopharmacol. 9 (Suppl. 1), 41-48.
39. Rossby S. P. and Sulser F. (1997) Antidepressants: beyond the synapse, in Antidepressants: New Pharmacological Strategies (Skolnick P., ed.), Humana, Totowa, NJ, pp. 195-212.
40. Sheng M., Cummings J., Roldan L. A., Jan Y. N., and Jan L. Y. (1994) Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368, 144-147.
41. Standaert D. G., Testa C. M., Young A. B., and Penney J. B (1994) Organization of N-methyl-D-aspartate glutamate receptor gene expression in the basal ganglia of the rat. J. Comp. Neurol. 343, 1-16.
42. Sugrue M. F. (1985) Delayed biochemical changes following antidepressant treatment. Psychopharmacology 21, 619-622.
43. Swerdlow N. R. and Koob G. F. (1987) Dopamine, schizophrenia, mania and depression: toward a unified hypothesis of cortico-striato-pallido-thalamic function. Behav. Brain Sci. 10, 197-245.
44. Trullas R. and Skolnick P. (1990) Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur. J. Pharmacol. 185, 1-10.
45. Vetulani J. (1991) The development of our understanding of the mechanism of action of antidepressant drugs. Polish J. Pharmacol. 43, 323-338.
46. Vetulani J. and Sulser F. (1975) Action of various antidepressant treatments reduces reactivity of noradrenergic cyclic AMP generating system in limbic forebrain. Nature 257, 495,496.
47. Von Lubitz D. K. J. E., Lin R. C-S., McKenzie R. J., Devlin T. M., McCabe R. T., and Skolnick P. (1992) A novel treatment of global cerebral ischaemia with a glycine partial agonist. Eur. J. Pharmacol. 219, 153-158.
48. Wafford K. A., Bain C. J., Le Bourdelles B., Whiting P. J., and Kemp J. A. (1993) Preferential co-assembly of recombinant NMDA receptors composed of three different subunits. Neuroreport 4, 1347-1349.
49. Watanabe M., Inoue Y., Sakimura K., and Mishina M. (1993) Distinct distributions of five N-methyl-D-aspartate receptor channel subunit mRNAs in the forebrain. J. Comp. Neurol. 338, 377-390.
50. Watanabe M., Mishina M., and Inoue Y. (1994) Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstem. J. Comp. Neurol. 343, 520-531.
51. Zukin R. S. and Bennett M. V. L. (1995) Alternatively spliced isoforms of the NMDAR1 receptor subunit. Trends Nenrosci. 18, 306-313.