Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors

Neuropsychopharmacology

Volumn 25, Issue 6, 2001, Pages 871-880

  Bymaster, Frank P ^a   Dreshfield Ahmad, Laura J ^a   Threlkeld, Penny G ^a   Shaw, Janice L ^a   Thompson, Linda ^a   Nelson, David L ^a   Hemrick Luecke, Susan K ^a   Wong, David T ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

5 HT receptors; Depression; Duloxetine; Norepinephrine uptake; Serotonin uptake; Venlafaxine

Indexed keywords

CHLORAMPHETAMINE; DULOXETINE; MONOAMINE; NORADRENALIN; NORADRENALIN TRANSPORTER; NORADRENALIN UPTAKE INHIBITOR; OXIDOPAMINE; SEROTONIN; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; VENLAFAXINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; HYPOTHALAMUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MONOAMINE METABOLISM; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; SEROTONIN BRAIN LEVEL; SEROTONIN RELEASE;

ANIMALS; BIOGENIC MONOAMINES; CARRIER PROTEINS; CELL LINE; CYCLOHEXANOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MONOAMINE OXIDASE; NERVE TISSUE PROTEINS; NEURONS; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; OXIDOPAMINE; P-CHLOROAMPHETAMINE; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SEROTONIN AGENTS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; SYMPATHOLYTICS; SYMPORTERS; THIOPHENES;

EID: 0035677108     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(01)00298-6     Document Type: Article

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