Allosteric modulators of GABAB receptors: Mechanism of action and therapeutic perspective

Current Neuropharmacology

Volumn 5, Issue 3, 2007, Pages 195-201

  Pin, Jean Philippe ^a,b   Prézeau, Laurent ^a,b  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b UNIV MONTPELLIER   (France)

Author keywords

Allosteric modulators; Anxiety; Baclofen; Class C GPCRs; Drug addiction

Indexed keywords

2,6 DI TERT BUTYL 4 (3 HYDROXY 2,2 DIMETHYLPROPYL)PHENOL; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; ANXIOLYTIC AGENT; BACLOFEN; BENZODIAZEPINE DERIVATIVE; CHLORIDE CHANNEL; G PROTEIN COUPLED RECEPTOR; HETERODIMER; METABOTROPIC RECEPTOR; N,N' DICYCLOPENTYL 2 METHYLTHIO 5 NITRO 4,6 PYRIMIDINEDIAMINE; NEUROTRANSMITTER;

ALCOHOLISM; ALLOSTERISM; ANXIETY DISORDER; BINDING AFFINITY; CENTRAL NERVOUS SYSTEM; CHANNEL GATING; COMBINATION CHEMOTHERAPY; DOSE RESPONSE; DRUG DEPENDENCE; DRUG EFFICACY; DRUG INDUSTRY; DRUG MECHANISM; DRUG PENETRATION; DRUG POTENCY; DRUG POTENTIATION; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG SCREENING; DRUG SELECTIVITY; DRUG TARGETING; HIGH THROUGHPUT SCREENING; HUMAN; IN VIVO STUDY; MONOTHERAPY; NONHUMAN; REVIEW; TRANQUILIZING ACTIVITY;

EID: 43249095827     PISSN: 1570159X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157015907781695919     Document Type: Review

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