Positive allosteric modulation of native and recombinant γ-aminobutyric acidb receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501

Molecular Pharmacology

Volumn 60, Issue 5, 2001, Pages 963-971

  Urwyler, Stephan ^a   Mosbacher, Johannes ^a   Lingenhoehl, Kurt ^a   Heid, Jakob ^a   Hofstetter, Karin ^a   Froestl, Wolfgang ^a   Bettler, Bernhard ^a   Kaupmann, Klemens ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DI TERT BUTYL 4 (3 HYDROXY 2,2 DIMETHYLPROPYL)PHENOL; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ALDEHYDE DERIVATIVE; BACLOFEN; CALCIUM ION; CGP 13501; CGP 7930; GLUTAMIC ACID; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MALONOBEN; METABOTROPIC RECEPTOR; POTASSIUM CHANNEL; PROPOFOL; RADIOLIGAND; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN MEMBRANE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CHO CELL; CONTROLLED STUDY; DRUG BINDING SITE; DRUG POTENCY; DRUG RECEPTOR BINDING; EMBRYO; GABAERGIC SYSTEM; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; XENOPUS LAEVIS;

EID: 0034760504     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.5.963     Document Type: Article

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