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Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 23, 2001, Pages 13402-13407

Positive allosteric modulators of metabotropic glutamate 1 receptor: Characterization, mechanism of action, and binding site

(8) Knoflach, Frédéric a Mutel, Vincent a,b Jolidon, Synèse a Kew, James N C a Malherbe, Pari a Vieira, Eric a Wichmann, Jürgen a Kemp, John A a

a F HOFFMANN LA ROCHE LTD (Switzerland)

b F HOFFMANN LA ROCHE LTD (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

(9H XANTHENE 9 CARBONYL)CARBAMIC ACID BUTYL ESTER; 2 (4 FLUOROPHENYL) 1 (TOLUENE 4 SULFONYL)PYRROLIDINE; DIPHENYLACETYLCARBAMIC ACID ETHYL ESTER; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMIC ACID; GLUTAMIC ACID DERIVATIVE; METABOTROPIC RECEPTOR; QUISQUALIC ACID; RECOMBINANT METABOTROPIC GLUTAMATE 1 RECEPTOR AGONIST; RECOMBINANT METABOTROPIC GLUTAMATE 1A; RECOMBINANT METABOTROPIC GLUTAMATE 5A; RECOMBINANT RECEPTOR; RO 01 6128; RO 67 4853; RO 67 7476; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID BRAIN LEVEL; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BRAIN SLICE; CHIMERA; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; ENHANCER REGION; HIPPOCAMPUS; HUMAN; HUMAN CELL; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RECEPTOR UPREGULATION; SYNAPTIC POTENTIAL;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CEREBELLUM; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; QUISQUALIC ACID; RADIOLIGAND ASSAY; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SYNAPTIC TRANSMISSION;

EID: 0035818605 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.231358298 Document Type: Article

Times cited : (220)

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