The C-terminal domains of the GABAB receptor subunits mediate intracellular trafficking but are not required for receptor signaling

Journal of Neuroscience

Volumn 21, Issue 4, 2001, Pages 1203-1210

  Calver, Andrew R ^a   Robbins, Melanie J ^a   Cosio, Christophe ^a   Rice, Simon Q J ^a   Babbs, Adam J ^a   Hirst, Warren D ^a   Boyfield, Izzy ^a   Wood, Martyn D ^a   Russell, Robert B ^a   Price, Gary W ^a   Couve, Andrés ^b   Moss, Stephen J ^b   Pangalos, Menelas N ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Chimeras; G protein coupling; GABAB; GPCR; Intracellular retention; Receptor subunits; Signaling; Trafficking

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; RECEPTOR SUBUNIT;

ARTICLE; BINDING SITE; BRAIN; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; SPINAL CORD; SYNAPTIC INHIBITION;

EID: 0035866089     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-04-01203.2001     Document Type: Article

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