Allosteric modulators of group I metabotropic glutamate receptors: Novel subtype-selective ligands and therapeutic perspectives

Current Opinion in Pharmacology

Volumn 2, Issue 1, 2002, Pages 43-49

  Gasparini, Fabrizio ^a   Kuhn, Rainer ^a   Pin, Jean Philippe ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b CCIPE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; AMINO ACID RECEPTOR BLOCKING AGENT; BAY 36 7620; CELL PROTEIN; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; HALOPERIDOL; LIGAND; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT THERAPY; ANXIETY NEUROSIS; ARTICLE; BINDING COMPETITION; BINDING SITE; CONCENTRATION RESPONSE; DISEASE MODEL; DRUG ABUSE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; DRUG RESEARCH; DRUG SCREENING; DRUG SELECTIVITY; DRUG TARGETING; EPILEPSY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; METABOLISM; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR DYSFUNCTION; NEUROLOGIC DISEASE; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PAIN; PARKINSON DISEASE; PHYSIOLOGY; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; RAT; SUBDURAL HEMATOMA; DRUG ANTAGONISM; REVIEW;

ALLOSTERIC REGULATION; ANIMALS; BINDING, COMPETITIVE; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; LIGANDS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0036462446     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4892(01)00119-9     Document Type: Review

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