-
1
-
-
0042767995
-
The dynamics of chromosome organization and gene regulation
-
Spector DL: The dynamics of chromosome organization and gene regulation. Annu. Rev. Biochem. 72, 573-608 (2003).
-
(2003)
Annu. Rev. Biochem
, vol.72
, pp. 573-608
-
-
Spector, D.L.1
-
2
-
-
25444502657
-
Artemis links ATM to double strand break rejoining
-
Jeggo PA, Lobrich M: Artemis links ATM to double strand break rejoining. Cell Cycle 4(3), 359-362 (2005).
-
(2005)
Cell Cycle
, vol.4
, Issue.3
, pp. 359-362
-
-
Jeggo, P.A.1
Lobrich, M.2
-
3
-
-
0032861343
-
-
Rogakou EP, Boon C, Redon C. Bonner WM: Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146(5), 905-916 (1999).
-
Rogakou EP, Boon C, Redon C. Bonner WM: Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146(5), 905-916 (1999).
-
-
-
-
4
-
-
0028360068
-
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
-
Drapkin R, Reardon JT, Ansari A et al.: Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II. Natute 368(6473). 769-772 (1994).
-
(1994)
Natute
, vol.368
, Issue.6473
, pp. 769-772
-
-
Drapkin, R.1
Reardon, J.T.2
Ansari, A.3
-
5
-
-
0033592950
-
DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes
-
Bailey SM, Meyne J, Chen DJ et al.: DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes. Proc. Natl Acad Sci. USA 96(26), 14899-14904 (1999).
-
(1999)
Proc. Natl Acad Sci. USA
, vol.96
, Issue.26
, pp. 14899-14904
-
-
Bailey, S.M.1
Meyne, J.2
Chen, D.J.3
-
8
-
-
42949168939
-
-
Background Information and Scientific Principles. In: Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V. National Academies Press, Washington, USA 9-64 (1990).
-
Background Information and Scientific Principles. In: Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V. National Academies Press, Washington, USA 9-64 (1990).
-
-
-
-
9
-
-
0033061765
-
DNA-dependent protein kinase content and activity in lung carcinoma cell lines: Correlation with intrinsic radiosensitivity
-
Sirzen F, Nilsson A. Zhivotovsky B, Lewensohn R: DNA-dependent protein kinase content and activity in lung carcinoma cell lines: correlation with intrinsic radiosensitivity. Eur. J. Cancer 35(1), 111-116 (1999).
-
(1999)
Eur. J. Cancer
, vol.35
, Issue.1
, pp. 111-116
-
-
Sirzen, F.1
Nilsson, A.2
Zhivotovsky, B.3
Lewensohn, R.4
-
10
-
-
0036293744
-
Association of DNA polymerase mu (pol mu) with Ku and ligase IV: Role for pol mu in end-joining double-strand break repair
-
Mahajan KN, Nick McElhinny SA, Mitchell BS, Ramsden DA: Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair. Mol. Cell. Biol. 22(14), 5194-5202 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, Issue.14
, pp. 5194-5202
-
-
Mahajan, K.N.1
Nick McElhinny, S.A.2
Mitchell, B.S.3
Ramsden, D.A.4
-
11
-
-
0037013895
-
Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining
-
Chappell C, Hanakahi LA, Karimi-Busheri F, Weinfeld, M, West SC: Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining. EMBO J. 21(11), 2827-2832(2002).
-
(2002)
EMBO J
, vol.21
, Issue.11
, pp. 2827-2832
-
-
Chappell, C.1
Hanakahi, L.A.2
Karimi-Busheri, F.3
Weinfeld, M.4
West, S.C.5
-
12
-
-
0028025020
-
Ku80: Product of the XRCC5 gene and its role in DNA repair and recombination
-
Taccioli GE, Gottlieb TM, Blunt T et al.: Ku80: product of the XRCC5 gene and its role in DNA repair and recombination. Science 265(5177), 1442-1445 (1994).
-
(1994)
Science
, vol.265
, Issue.5177
, pp. 1442-1445
-
-
Taccioli, G.E.1
Gottlieb, T.M.2
Blunt, T.3
-
13
-
-
0029585872
-
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
-
Li Z. Otevrel T, Gao Y et al.: The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell 83(7). 1079-1089 (1995).
-
(1995)
Cell
, vol.83
, Issue.7
, pp. 1079-1089
-
-
Li, Z.1
Otevrel, T.2
Gao, Y.3
-
14
-
-
0030858967
-
-
Gu Y, Jin S, Gao Y. Weaver DT, Alt FW: Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc. Natl Acad Sci. USA 94(15), 8076-8081 (1997).
-
Gu Y, Jin S, Gao Y. Weaver DT, Alt FW: Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination. Proc. Natl Acad Sci. USA 94(15), 8076-8081 (1997).
-
-
-
-
15
-
-
0032167446
-
A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination
-
Gao Y, Chaudhuri J, Zhu C, Davidson L. Weaver DT, Alt FW: A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination. Immunity 9(3), 367-376 (1998).
-
(1998)
Immunity
, vol.9
, Issue.3
, pp. 367-376
-
-
Gao, Y.1
Chaudhuri, J.2
Zhu, C.3
Davidson, L.4
Weaver, D.T.5
Alt, F.W.6
-
16
-
-
0031433517
-
Growth retardation and leaky SCID phenotype of Ku70-deficient mice
-
Gu Y, Seidi KJ. Rathbun GA et al.: Growth retardation and leaky SCID phenotype of Ku70-deficient mice. Immunity 7(5), 653-665 (1997).
-
(1997)
Immunity
, vol.7
, Issue.5
, pp. 653-665
-
-
Gu, Y.1
Seidi, K.J.2
Rathbun, G.A.3
-
17
-
-
0032167545
-
Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity
-
Taccioli GE, Amatucci AG, Beamish HJ et al.: Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity. Immunity9(3), 355-366 (1998).
-
(1998)
Immunity
, vol.9
, Issue.3
, pp. 355-366
-
-
Taccioli, G.E.1
Amatucci, A.G.2
Beamish, H.J.3
-
18
-
-
0032417640
-
A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis
-
Gao Y, Sun Y, Frank KM et al.: A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell 95(7), 891-902 (1998).
-
(1998)
Cell
, vol.95
, Issue.7
, pp. 891-902
-
-
Gao, Y.1
Sun, Y.2
Frank, K.M.3
-
19
-
-
0032585526
-
Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
-
Barnes DE, Stamp G, Rosewell I, Denzel A, Lindahl T: Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Curr. Biol. 8(25), 1395-1398 (1998).
-
(1998)
Curr. Biol
, vol.8
, Issue.25
, pp. 1395-1398
-
-
Barnes, D.E.1
Stamp, G.2
Rosewell, I.3
Denzel, A.4
Lindahl, T.5
-
20
-
-
0034662649
-
A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse
-
Okayasu R, Suetomi K, Yu Y, Silver A, Bedford JS, Cox R, Ullrich RL: A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse. Cancer Res. 60(16), 4342-4345 (2000).
-
(2000)
Cancer Res
, vol.60
, Issue.16
, pp. 4342-4345
-
-
Okayasu, R.1
Suetomi, K.2
Yu, Y.3
Silver, A.4
Bedford, J.S.5
Cox, R.6
Ullrich, R.L.7
-
21
-
-
0034889360
-
Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system
-
Aravind L and Koonin EV: Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system. Genome Res. 11(8), 1365-1374 (2001).
-
(2001)
Genome Res
, vol.11
, Issue.8
, pp. 1365-1374
-
-
Aravind, L.1
Koonin, E.V.2
-
22
-
-
0035997348
-
V(D)J recombination: RAG proteins, repair factors, and regulation
-
Gellert M: V(D)J recombination: RAG proteins, repair factors, and regulation. Annu. Rev. Biochem. 71, 101-132 (2002).
-
(2002)
Annu. Rev. Biochem
, vol.71
, pp. 101-132
-
-
Gellert, M.1
-
23
-
-
0032489520
-
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS. Bonner WM: DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273(10), 5858-5868. (1998).
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS. Bonner WM: DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273(10), 5858-5868. (1998).
-
-
-
-
24
-
-
33845340785
-
H2AX chromatin structures and their response to DNA damage revealed by 4Pi microscopy
-
Bewersdorf J, Bennett BT, Knight KL: H2AX chromatin structures and their response to DNA damage revealed by 4Pi microscopy. Proc. Natl Acad. Sci. USA 103(48), 18137-18142 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.48
, pp. 18137-18142
-
-
Bewersdorf, J.1
Bennett, B.T.2
Knight, K.L.3
-
25
-
-
33646446295
-
Imaging features that discriminate between foci induced by high- and low-LET radiation in human fibroblasts
-
Costes SV, Boissiere A, Ravani S, Romano R, Parvin B, Barcellos-Hoff MH: Imaging features that discriminate between foci induced by high- and low-LET radiation in human fibroblasts. Radiat. Res. 165(5), 505-515 (2006).
-
(2006)
Radiat. Res
, vol.165
, Issue.5
, pp. 505-515
-
-
Costes, S.V.1
Boissiere, A.2
Ravani, S.3
Romano, R.4
Parvin, B.5
Barcellos-Hoff, M.H.6
-
26
-
-
0037884963
-
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
-
Rothkamm K, Lobrich M: Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc. Natl. Acad. Sci. USA 100(9), 5057-5062 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.9
, pp. 5057-5062
-
-
Rothkamm, K.1
Lobrich, M.2
-
27
-
-
4644257681
-
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break
-
Shroff R, Arbel-Eden A, Pilch D et al.: Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr. Biol. 14(19), 1703-1711 (2004).
-
(2004)
Curr. Biol
, vol.14
, Issue.19
, pp. 1703-1711
-
-
Shroff, R.1
Arbel-Eden, A.2
Pilch, D.3
-
28
-
-
33644905252
-
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
-
Kruhlak MJ, Celeste A, Dellaire G et al.: Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J. Cell Biol. 172(6), 823-834 (2006).
-
(2006)
J. Cell Biol
, vol.172
, Issue.6
, pp. 823-834
-
-
Kruhlak, M.J.1
Celeste, A.2
Dellaire, G.3
-
29
-
-
0034739853
-
p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
-
Schultz LB, Chehab NH, Malikzay A, Halazonetis TD: p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol. 151(7), 1381-1390 (2000).
-
(2000)
J. Cell Biol
, vol.151
, Issue.7
, pp. 1381-1390
-
-
Schultz, L.B.1
Chehab, N.H.2
Malikzay, A.3
Halazonetis, T.D.4
-
30
-
-
0037468192
-
MDC1 is a mediator of the mammalian DNA damage checkpoint
-
Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ: MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 421(6926), 961-966 (2003).
-
(2003)
Nature
, vol.421
, Issue.6926
, pp. 961-966
-
-
Stewart, G.S.1
Wang, B.2
Bignell, C.R.3
Taylor, A.M.4
Elledge, S.J.5
-
31
-
-
0141780833
-
NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors
-
Xu X, Stern DF: NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. FASEB J. 17(13), 1842-1848 (2003).
-
(2003)
FASEB J
, vol.17
, Issue.13
, pp. 1842-1848
-
-
Xu, X.1
Stern, D.F.2
-
32
-
-
0037417373
-
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response
-
Kao GD, McKenna WG, Guenther MG. Muschel RJ. Lazar MA, Yen TJ: Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J. Cell Biol. 160(7), 1017-1027 (2003).
-
(2003)
J. Cell Biol
, vol.160
, Issue.7
, pp. 1017-1027
-
-
Kao, G.D.1
McKenna, W.G.2
Guenther, M.G.3
Muschel, R.J.4
Lazar, M.A.5
Yen, T.J.6
-
33
-
-
0034749425
-
DNA damage-dependent nuclear dynamics of the Mre11 complex
-
Mirzoeva OK, Petrini JH: DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol. Cell. Biol. 21(1), 281-288 (2001).
-
(2001)
Mol. Cell. Biol
, vol.21
, Issue.1
, pp. 281-288
-
-
Mirzoeva, O.K.1
Petrini, J.H.2
-
35
-
-
0029780351
-
The molecular structure of green fluorescent protein
-
Yang F, Moss LG, Phillips GN Jr: The molecular structure of green fluorescent protein. Nat. Biotechnol. 14(10), 1246-1251 (1996).
-
(1996)
Nat. Biotechnol
, vol.14
, Issue.10
, pp. 1246-1251
-
-
Yang, F.1
Moss, L.G.2
Phillips Jr, G.N.3
-
36
-
-
0029847806
-
-
Ormo M, Cubitt AB, Kallio K, Gross LA, Tsien RY. Remington SJ: Crystal structure of the Aequorea victoria green fluorescent protein. Science 273(5280), 1392-1395 (1996).
-
Ormo M, Cubitt AB, Kallio K, Gross LA, Tsien RY. Remington SJ: Crystal structure of the Aequorea victoria green fluorescent protein. Science 273(5280), 1392-1395 (1996).
-
-
-
-
37
-
-
19644391139
-
Targeting quantum dots to surface proteins in living cells with biotin ligase
-
Howarth M, Takao K, Hayashi Y, Ting AY: Targeting quantum dots to surface proteins in living cells with biotin ligase. Proc. Natl Acad. Sci. USA 102(21), 7583-7588 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.21
, pp. 7583-7588
-
-
Howarth, M.1
Takao, K.2
Hayashi, Y.3
Ting, A.Y.4
-
38
-
-
34248993985
-
Phage display evolution of a peptide substrate for yeast biotin ligase and application to two-color quantum dot labeling of cell surface proteins
-
Chen I, Choi YA, Ting A: Phage display evolution of a peptide substrate for yeast biotin ligase and application to two-color quantum dot labeling of cell surface proteins. J. Am. Chem. Soc. 2007(129), 6619-6625 (2007).
-
(2007)
J. Am. Chem. Soc
, vol.2007
, Issue.129
, pp. 6619-6625
-
-
Chen, I.1
Choi, Y.A.2
Ting, A.3
-
39
-
-
0032566763
-
Quantum dot bioconjugates for ultrasensitive nonisotopic. detection
-
Chan WC, Nie S: Quantum dot bioconjugates for ultrasensitive nonisotopic. detection. Science 281(5385), 2016-2018 (1998).
-
(1998)
Science
, vol.281
, Issue.5385
, pp. 2016-2018
-
-
Chan, W.C.1
Nie, S.2
-
40
-
-
0037070627
-
Stabilization of inorganic nanocrystals by organic dendrons
-
Wang YA, Li JJ, Chen H, Peng X: Stabilization of inorganic nanocrystals by organic dendrons. J. Am. Chem. Soc. 124(10), 2293-2298 (2002).
-
(2002)
J. Am. Chem. Soc
, vol.124
, Issue.10
, pp. 2293-2298
-
-
Wang, Y.A.1
Li, J.J.2
Chen, H.3
Peng, X.4
-
41
-
-
34250208736
-
Bioconjugated quantum dots for multiplexed and quantitative immunohistochemistry
-
Xing Y CQ, Shen C, Kong KY et al.: Bioconjugated quantum dots for multiplexed and quantitative immunohistochemistry. Nat. Protoc. 2(5), 1152-1165 (2007).
-
(2007)
Nat. Protoc
, vol.2
, Issue.5
, pp. 1152-1165
-
-
Xing, Y.C.1
Shen, C.2
Kong, K.Y.3
-
42
-
-
33746774237
-
Self-assembled quantum dot-peptide bioconjugates for selective intracellular delivery
-
Delahanty JB, Medintz IL, Pons T, Brunel FM, Dawson PE, Mattoussi H: Self-assembled quantum dot-peptide bioconjugates for selective intracellular delivery. Bioconjug. Chem. 17(4). 920-927 (2006).
-
(2006)
Bioconjug. Chem
, vol.17
, Issue.4
, pp. 920-927
-
-
Delahanty, J.B.1
Medintz, I.L.2
Pons, T.3
Brunel, F.M.4
Dawson, P.E.5
Mattoussi, H.6
-
43
-
-
33947426789
-
Cell-penetrating quantum dots based on multivalent and endosome-disrupting surface coatings
-
Duan H and Nie S: Cell-penetrating quantum dots based on multivalent and endosome-disrupting surface coatings. J. Am. Chem. Soc. 129(11), 3333-3338 (2007).
-
(2007)
J. Am. Chem. Soc
, vol.129
, Issue.11
, pp. 3333-3338
-
-
Duan, H.1
Nie, S.2
-
44
-
-
0026087508
-
Measurement of DNA double-strand breaks in CHO cells at various stages of the cell cycle using pulsed field gel electrophoresis: Calibration by means of 1251 decay
-
Iliakis GE, Cicilioni O, Metzger L: Measurement of DNA double-strand breaks in CHO cells at various stages of the cell cycle using pulsed field gel electrophoresis: calibration by means of 1251 decay. Int. J. Radiat Biol. 59(2), 343-357 (1991).
-
(1991)
Int. J. Radiat Biol
, vol.59
, Issue.2
, pp. 343-357
-
-
Iliakis, G.E.1
Cicilioni, O.2
Metzger, L.3
-
45
-
-
0028290852
-
Whitaker SJ, McMillan TJ: A comparison of methods for calculating DNA double-strand break induction frequency in mammalian cells by pulsed-field gel electrophoresis
-
Ruiz de Almodovar JM, Steel GG. Whitaker SJ, McMillan TJ: A comparison of methods for calculating DNA double-strand break induction frequency in mammalian cells by pulsed-field gel electrophoresis. Int. J. Radiat. Biol. 65(6), 641-649 (1994).
-
(1994)
Int. J. Radiat. Biol
, vol.65
, Issue.6
, pp. 641-649
-
-
Ruiz de Almodovar, J.M.1
Steel, G.G.2
-
46
-
-
0032412476
-
Mating-type gene switching in Saccharomyces cerevisiae
-
Haber JE: Mating-type gene switching in Saccharomyces cerevisiae. Annu. Rev. Genet. 32, 561-599 (1998).
-
(1998)
Annu. Rev. Genet
, vol.32
, pp. 561-599
-
-
Haber, J.E.1
-
47
-
-
34447574977
-
Positional stability of single double-strand breaks in mammalian cells
-
Soutoglou E, Dorn JF. Sengupta K et al.: Positional stability of single double-strand breaks in mammalian cells. Nat. Cell. Biol. 9(6), 675-682 (2007).
-
(2007)
Nat. Cell. Biol
, vol.9
, Issue.6
, pp. 675-682
-
-
Soutoglou, E.1
Dorn, J.F.2
Sengupta, K.3
-
48
-
-
34249945258
-
Far-field optical nanoscopy
-
Hell SW: Far-field optical nanoscopy. Science 316(5828), 1153-1158 (2007).
-
(2007)
Science
, vol.316
, Issue.5828
, pp. 1153-1158
-
-
Hell, S.W.1
-
49
-
-
30744465308
-
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals
-
Lou Z, Minter-Dykhouse K, Franco S et al.: MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. Mol. Cell 21(2), 187-200.(2006).
-
(2006)
Mol. Cell
, vol.21
, Issue.2
, pp. 187-200
-
-
Lou, Z.1
Minter-Dykhouse, K.2
Franco, S.3
-
50
-
-
34848843525
-
Rag mutations reveal robust alternative end joining
-
Corneo B, Wendland R. Deriano L, Cui X, Kelin A, Roth DB: Rag mutations reveal robust alternative end joining. Nature 449(7161), 483-486 (2007).
-
(2007)
Nature
, vol.449
, Issue.7161
, pp. 483-486
-
-
Corneo, B.1
Wendland, R.2
Deriano, L.3
Cui, X.4
Kelin, A.5
Roth, D.B.6
-
51
-
-
27744530147
-
Zinc finger nuclease: Custom-designed molecular scissors for genome engineering of plant and mammallan cell
-
Durai S, Mani M, Kandavelou K. Wu J, Porteus MH, Chandrasegaran S: Zinc finger nuclease: custom-designed molecular scissors for genome engineering of plant and mammallan cell. Nucl. Acids Res. 33(18), 5978-5990 (2005).
-
(2005)
Nucl. Acids Res
, vol.33
, Issue.18
, pp. 5978-5990
-
-
Durai, S.1
Mani, M.2
Kandavelou, K.3
Wu, J.4
Porteus, M.H.5
Chandrasegaran, S.6
-
52
-
-
1942421722
-
RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination
-
Lee GS, Neiditch, MB, Salus, SS, Roth DB: RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination. Cell 117(2), 171-184 (2004).
-
(2004)
Cell
, vol.117
, Issue.2
, pp. 171-184
-
-
Lee, G.S.1
Neiditch, M.B.2
Salus, S.S.3
Roth, D.B.4
-
53
-
-
42949086398
-
-
Doxil® doxorubicin HC1 liposome injection, package insert. Ortho Biotech Products L.P, Raritan, NJ, USA
-
Doxil® (doxorubicin HC1 liposome injection), package insert. Ortho Biotech Products L.P., Raritan, NJ, USA.
-
-
-
-
54
-
-
14544300545
-
-
Pan X, Lee RJ: Tumour-selective drug delivery via folate receptor-targeted liposomes. Expert Opin. Drug Deliv. 1 (1). 7-17 (2004).
-
Pan X, Lee RJ: Tumour-selective drug delivery via folate receptor-targeted liposomes. Expert Opin. Drug Deliv. 1 (1). 7-17 (2004).
-
-
-
-
55
-
-
14644392093
-
Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay
-
Parker N, Turk MJ, Westrick E, Lewis JD. Low PS, Leamon CP: Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal. Biochem. 338(2), 284-293 (2005).
-
(2005)
Anal. Biochem
, vol.338
, Issue.2
, pp. 284-293
-
-
Parker, N.1
Turk, M.J.2
Westrick, E.3
Lewis, J.D.4
Low, P.S.5
Leamon, C.P.6
-
56
-
-
2342595835
-
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
-
Wadia JS, Stan RV, Dowdy SF: Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat. Med. 10(3), 310-315 (2004).
-
(2004)
Nat. Med
, vol.10
, Issue.3
, pp. 310-315
-
-
Wadia, J.S.1
Stan, R.V.2
Dowdy, S.F.3
-
57
-
-
11144326721
-
Quantum dots targeted to the assigned organelle in living cells
-
Hoshino, A, Fujioka K, Oku T et al.: Quantum dots targeted to the assigned organelle in living cells. Microbiol. Immunol. 48(12), 985-994 (2004).
-
(2004)
Microbiol. Immunol
, vol.48
, Issue.12
, pp. 985-994
-
-
Hoshino, A.1
Fujioka, K.2
Oku, T.3
-
58
-
-
0344586930
-
Targeting tumor cells by enhancing radiation sensitivity
-
McKenna WG, Muschel RJ: Targeting tumor cells by enhancing radiation sensitivity. Genes Chromosomes Cancer 38(4), 330-338 (2003).
-
(2003)
Genes Chromosomes Cancer
, vol.38
, Issue.4
, pp. 330-338
-
-
McKenna, W.G.1
Muschel, R.J.2
-
59
-
-
15744372810
-
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
-
Pao W, Wang, TY, Riely GJ et al.: KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med. 2. e17 (2005).
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
-
60
-
-
0032840918
-
Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
-
Walboomers JM, Jacobs MV, Manos MM et al.: Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J. Pathol. 189(1), 12-19 (1999).
-
(1999)
J. Pathol
, vol.189
, Issue.1
, pp. 12-19
-
-
Walboomers, J.M.1
Jacobs, M.V.2
Manos, M.M.3
-
61
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P: Global cancer statistics, 2002. CA Cancer J. Clin. 55(2), 74-108 (2005).
-
(2005)
CA Cancer J. Clin
, vol.55
, Issue.2
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
62
-
-
34648825044
-
Prevalence of human papillomavirus in squamous cell carcinoma of the tongue
-
Silva CE, Silva ID, Cerri A, Weckx LL: Prevalence of human papillomavirus in squamous cell carcinoma of the tongue. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod. 104(4), 497-500 (2007).
-
(2007)
Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod
, vol.104
, Issue.4
, pp. 497-500
-
-
Silva, C.E.1
Silva, I.D.2
Cerri, A.3
Weckx, L.L.4
-
63
-
-
34247344009
-
Human papillomavirus 16 and head and neck squamous cell carcinoma
-
Furniss CS. McClean MD, Smith JF et al.: Human papillomavirus 16 and head and neck squamous cell carcinoma. Int. J. Cancer 120(11), 2386-2392 (2007).
-
(2007)
Int. J. Cancer
, vol.120
, Issue.11
, pp. 2386-2392
-
-
Furniss, C.S.1
McClean, M.D.2
Smith, J.F.3
-
64
-
-
34248350674
-
Case-control study of human papillomavirus and oropharyngeal cancer
-
D'Souza G, Kreimer AR, Viscidi R et al.: Case-control study of human papillomavirus and oropharyngeal cancer. N. Engl. J. Med. 356(19), 1944-1956 (2007).
-
(2007)
N. Engl. J. Med
, vol.356
, Issue.19
, pp. 1944-1956
-
-
D'Souza, G.1
Kreimer, A.R.2
Viscidi, R.3
-
65
-
-
0034028826
-
Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy
-
Gustafsson MG: Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy. J. Microsc. 198(Pt 2), 82-87 (2000).
-
(2000)
J. Microsc
, vol.198
, Issue.PART 2
, pp. 82-87
-
-
Gustafsson, M.G.1
-
66
-
-
24944539530
-
Nonlinear structured-illumination microscopy: Wide-field fluorescence imaging with theoretically unlimited resolution
-
Gustafsson MG: Nonlinear structured-illumination microscopy: wide-field fluorescence imaging with theoretically unlimited resolution. Proc. Natl Acad. Sci. USA 102(37), 13081-13086 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.37
, pp. 13081-13086
-
-
Gustafsson, M.G.1
-
67
-
-
0036674522
-
Saturated patterned excitation microscopy - a concept for optical resolution improvement
-
Heintzmann R, Jovin TM, Cremer C: Saturated patterned excitation microscopy - a concept for optical resolution improvement. J. Opt. Soc. Am. 19(8), 1599-1609 (2002).
-
(2002)
J. Opt. Soc. Am
, vol.19
, Issue.8
, pp. 1599-1609
-
-
Heintzmann, R.1
Jovin, T.M.2
Cremer, C.3
-
68
-
-
0242322565
-
Toward fluorescence nanoscopy
-
Hell SW: Toward fluorescence nanoscopy. Nat. Biotechnol. 21(11), 1347-1355 (2003).
-
(2003)
Nat. Biotechnol
, vol.21
, Issue.11
, pp. 1347-1355
-
-
Hell, S.W.1
-
69
-
-
3843104585
-
Nanometer-localized multiple single-molecule fluorescence microscopy
-
Qu X, Wu D, Mets L, Scherer NF: Nanometer-localized multiple single-molecule fluorescence microscopy. Proc. Natl Acad. Sci. USA 101 (31), 11298-11303 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.31
, pp. 11298-11303
-
-
Qu, X.1
Wu, D.2
Mets, L.3
Scherer, N.F.4
-
70
-
-
33749026335
-
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
-
Rust MJ, Bates M, Zhuang X: Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). Nat. Methods 3(10), 793-795 (2006).
-
(2006)
Nat. Methods
, vol.3
, Issue.10
, pp. 793-795
-
-
Rust, M.J.1
Bates, M.2
Zhuang, X.3
-
71
-
-
13844276672
-
Site-specific labeling of proteins with small molecules in live cells
-
Chen I, Ting AY: Site-specific labeling of proteins with small molecules in live cells. Curr. Opin. Biotechnol. 16(1), 35-40 (2005).
-
(2005)
Curr. Opin. Biotechnol
, vol.16
, Issue.1
, pp. 35-40
-
-
Chen, I.1
Ting, A.Y.2
-
72
-
-
11144267737
-
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma spp. red fluorescent protein
-
Shaner NC, Campbell RE, Steinbach PA, Giepmans BN, Palmer AE, Tsien RY: Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma spp. red fluorescent protein. Nat. Biotechnol. 22(12), 1567-1572 (2004).
-
(2004)
Nat. Biotechnol
, vol.22
, Issue.12
, pp. 1567-1572
-
-
Shaner, N.C.1
Campbell, R.E.2
Steinbach, P.A.3
Giepmans, B.N.4
Palmer, A.E.5
Tsien, R.Y.6
-
73
-
-
0032867477
-
Fluorescent proteins from nonbioluminescent Anthozoa species
-
Matz MV, Fradkov AF, Labas YA et al.: Fluorescent proteins from nonbioluminescent Anthozoa species. Nat. Biotechnol. 17(10), 969-973 (1999).
-
(1999)
Nat. Biotechnol
, vol.17
, Issue.10
, pp. 969-973
-
-
Matz, M.V.1
Fradkov, A.F.2
Labas, Y.A.3
-
74
-
-
34347251261
-
Evolving proteins in mammalian cells using somatic hypermutation
-
Wang L, Tsien RY: Evolving proteins in mammalian cells using somatic hypermutation. Nat. Protoc. 1(3), 1346-1350 (2006).
-
(2006)
Nat. Protoc
, vol.1
, Issue.3
, pp. 1346-1350
-
-
Wang, L.1
Tsien, R.Y.2
-
75
-
-
33644516580
-
Specific and stable fluorescence labeling of histidine-tagged proteins for dissecting multi-protein complex formation
-
Lata S, Gavuta M, Tampé R, Piehler J: Specific and stable fluorescence labeling of histidine-tagged proteins for dissecting multi-protein complex formation. J. Am. Chem. Soc. 128(7), 2365-2372 (2006).
-
(2006)
J. Am. Chem. Soc
, vol.128
, Issue.7
, pp. 2365-2372
-
-
Lata, S.1
Gavuta, M.2
Tampé, R.3
Piehler, J.4
-
76
-
-
33847158264
-
Site-specific fluorescent labeling of poly-histidine sequences using a metal-chelating cysteine
-
Krishnan B, Szymanska A, Gierasch LM: Site-specific fluorescent labeling of poly-histidine sequences using a metal-chelating cysteine. Chem. Biol. Drug Des. 69(1), 31-40 (2007).
-
(2007)
Chem. Biol. Drug Des
, vol.69
, Issue.1
, pp. 31-40
-
-
Krishnan, B.1
Szymanska, A.2
Gierasch, L.M.3
-
77
-
-
0032403218
-
Evolution of peptides that modulate the spectral qualities of bound, small-molecule fluorophores
-
Rozinov MN, Nolan GP: Evolution of peptides that modulate the spectral qualities of bound, small-molecule fluorophores. Chem. Biol. 5(12), 713-728 (1998).
-
(1998)
Chem. Biol
, vol.5
, Issue.12
, pp. 713-728
-
-
Rozinov, M.N.1
Nolan, G.P.2
-
78
-
-
0037134035
-
Multicolor and electron microscopic imaging of connexin trafficking
-
Gaietta G, Deerinck TJ, Adams SR et al.: Multicolor and electron microscopic imaging of connexin trafficking. Science 296(5567), 503-507 (2002).
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 503-507
-
-
Gaietta, G.1
Deerinck, T.J.2
Adams, S.R.3
-
79
-
-
27144448780
-
Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity
-
Martin BR, Giepmans BN, Adams SR, Tsien RY: Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity. Nat. Biotechnol. 23(10), 1308-1314 (2005).
-
(2005)
Nat. Biotechnol
, vol.23
, Issue.10
, pp. 1308-1314
-
-
Martin, B.R.1
Giepmans, B.N.2
Adams, S.R.3
Tsien, R.Y.4
-
80
-
-
18744406025
-
In vivo protein labeling with trimethoprim conjugates: A flexible chemical tag
-
Miller LW, Cai Y, Sheetz MP, Cornish VW: In vivo protein labeling with trimethoprim conjugates: a flexible chemical tag. Nat. Methods 2(4), 255-257 (2005).
-
(2005)
Nat. Methods
, vol.2
, Issue.4
, pp. 255-257
-
-
Miller, L.W.1
Cai, Y.2
Sheetz, M.P.3
Cornish, V.W.4
-
81
-
-
3042793777
-
A general approach for chemical labeling and rapid, spatially controlled protein inactivation
-
Marks KM, Braun PD, Nolah GP: A general approach for chemical labeling and rapid, spatially controlled protein inactivation. Proc. Natl Acad. Sci. USA 101(27), 9982-9987 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.27
, pp. 9982-9987
-
-
Marks, K.M.1
Braun, P.D.2
Nolah, G.P.3
-
82
-
-
0037225952
-
A general method for the covalent labeling of fusion proteins with small molecules in vivo
-
Keppler A, Gendreizig S, Gronemeyer T, Pick H, Vogel H, Johnsson K: A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat. Biotechol. 21(1), 86-89 (2002).
-
(2002)
Nat. Biotechol
, vol.21
, Issue.1
, pp. 86-89
-
-
Keppler, A.1
Gendreizig, S.2
Gronemeyer, T.3
Pick, H.4
Vogel, H.5
Johnsson, K.6
-
83
-
-
3042798464
-
Labeling of fusion proteins with synthetic fluorophores in live cells
-
Keppler A, Pick H, Arrivoli C, Vogel H, Johnsson K: Labeling of fusion proteins with synthetic fluorophores in live cells. Proc. Natl Acad. Sci. USA 101(27), 9955-9959 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.27
, pp. 9955-9959
-
-
Keppler, A.1
Pick, H.2
Arrivoli, C.3
Vogel, H.4
Johnsson, K.5
-
84
-
-
3242754218
-
Specific labeling of cell surface proteins with chemically diverse compounds
-
George N, Pick H, Vogel H, Johnsson N, Johnsson K: Specific labeling of cell surface proteins with chemically diverse compounds. J. Am. Chem. Soc. 126(29), 8896-8897 (2004).
-
(2004)
J. Am. Chem. Soc
, vol.126
, Issue.29
, pp. 8896-8897
-
-
George, N.1
Pick, H.2
Vogel, H.3
Johnsson, N.4
Johnsson, K.5
-
85
-
-
33646714595
-
Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair
-
Spagnolo L, Rivera-Calzada A, Pearl LH, Llorca O: Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair. Mol. Cell 22(4), 511-519 (2006).
-
(2006)
Mol. Cell
, vol.22
, Issue.4
, pp. 511-519
-
-
Spagnolo, L.1
Rivera-Calzada, A.2
Pearl, L.H.3
Llorca, O.4
-
86
-
-
0344874141
-
Cell-permeable small molecule probes for site-specific labeling of proteins
-
Yeo DS, Srinivasan R, Uttamchandani M, Chen GY, Zhu Q, Yao SQ: Cell-permeable small molecule probes for site-specific labeling of proteins. Chem. Commun. (Camb) 7(23), 2870-2871 (2003).
-
(2003)
Chem. Commun. (Camb)
, vol.7
, Issue.23
, pp. 2870-2871
-
-
Yeo, D.S.1
Srinivasan, R.2
Uttamchandani, M.3
Chen, G.Y.4
Zhu, Q.5
Yao, S.Q.6
|