Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response

Journal of Cell Biology

Volumn 160, Issue 7, 2003, Pages 1017-1027

  Kao, Gary D ^a,c   McKenna, W Gillies ^a   Guenther, Matthew G ^a   Muschel, Ruth J ^a   Lazar, Mitchell A ^a   Yen, Tim J ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b FOX CHASE CANCER CENTER   (United States)

^c HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

53BP1; DNA damage; G2 checkpoint; HDAC4; Irradiation

Indexed keywords

DOUBLE STRANDED DNA; HISTONE DEACETYLASE; HISTONE DEACETYLASE 4; PROTEIN; PROTEIN 53BP1; RAD51 PROTEIN; RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G2 PHASE; CELL DEATH; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; INTERPHASE; IRRADIATION; LETHAL DOSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RADIATION DOSE; RADIOSENSITIVITY; RNA ANALYSIS; RNA INTERFERENCE;

CARRIER PROTEINS; CELL LINE; CELL NUCLEUS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, RADIATION; ETOPOSIDE; G2 PHASE; GAMMA RAYS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; MUTATION; NUCLEAR PROTEINS; NUCLEIC ACID SYNTHESIS INHIBITORS; PHOSPHOPROTEINS; PROTEIN SYNTHESIS INHIBITORS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED;

EID: 0037417373     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200209065     Document Type: Article

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