-
1
-
-
38849143765
-
Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators
-
Supuran CT. Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators. Nat Rev Drug Discov 2008; 7: 168-181.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 168-181
-
-
Supuran, C.T.1
-
2
-
-
44349107478
-
-
Supuran CT, Scozzafava, A., Conway, J. (Eds.): Carbonic anhydrase - Its inhibitors and activators, CRC Press, Boca Raton (FL), USA, 2004, pp. 1-363, and reference cited therein.
-
Supuran CT, Scozzafava, A., Conway, J. (Eds.): Carbonic anhydrase - Its inhibitors and activators, CRC Press, Boca Raton (FL), USA, 2004, pp. 1-363, and reference cited therein.
-
-
-
-
7
-
-
0034712970
-
A biological function for cadmium in marine diatoms
-
Lane TW, Morel FM. A biological function for cadmium in marine diatoms. Proc Natl Acad Sci USA 2000; 97: 4627-31.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4627-4631
-
-
Lane, T.W.1
Morel, F.M.2
-
8
-
-
28044448499
-
Characterization of CA XV, a new GPI-anchored form of carbonic anhydrase
-
Hilvo M. Tolvanen M. Clark A. Shen B. Shah Waheed A, et al. Characterization of CA XV, a new GPI-anchored form of carbonic anhydrase. Biochem J 2005; 392: 93-92.
-
(2005)
Biochem J
, vol.392
, pp. 93-92
-
-
Hilvo, M.1
Tolvanen, M.2
Clark, A.3
Shen, B.4
Shah Waheed, A.5
-
9
-
-
28144452672
-
Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and suifamate inhibitors
-
Nishimori I, Vullo D, Innocenti A, Scozzafava A, Mastrolorenzo A, Supuran CT. Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and suifamate inhibitors. J Med Chem 2005; 48: 7860-6
-
(2005)
J Med Chem
, vol.48
, pp. 7860-7866
-
-
Nishimori, I.1
Vullo, D.2
Innocenti, A.3
Scozzafava, A.4
Mastrolorenzo, A.5
Supuran, C.T.6
-
10
-
-
33846458646
-
Carbonic anhydrase inhibitors. DNA cloning, characterization and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors
-
Nishimori I, Minakuchi T, Onishi S, Vullo D, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. DNA cloning, characterization and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors. J Med Chem 2007; 50: 381-8
-
(2007)
J Med Chem
, vol.50
, pp. 381-388
-
-
Nishimori, I.1
Minakuchi, T.2
Onishi, S.3
Vullo, D.4
Scozzafava, A.5
Supuran, C.T.6
-
11
-
-
16244364782
-
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides
-
Vullo D, Voipio J, Innocenti A, Rivera C, Ranki H, Scozzafava A, et al. Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett 2005: 15: 971-6
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 971-976
-
-
Vullo, D.1
Voipio, J.2
Innocenti, A.3
Rivera, C.4
Ranki, H.5
Scozzafava, A.6
-
12
-
-
0035859892
-
Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein over-expressed in certain cancer tumor cell
-
Whittington DA, Waheed A, Ulmasov B, Shah GN, Grubb JH, Sly WS, et al. Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein over-expressed in certain cancer tumor cell. Proc Natl Acad Sci USA 2001; 98: 9595-50
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9595-9650
-
-
Whittington, D.A.1
Waheed, A.2
Ulmasov, B.3
Shah, G.N.4
Grubb, J.H.5
Sly, W.S.6
-
13
-
-
9144220136
-
Characterization of CA XIII, a novel member of the carbonic andhydrase isozyme family
-
Lehtonen J, Shen B, Vihinen M, Casini A, Scozzafava A, Supuran CT, et al. Characterization of CA XIII, a novel member of the carbonic andhydrase isozyme family. J Biol Chem 2004; 279: 2719-27.
-
(2004)
J Biol Chem
, vol.279
, pp. 2719-2727
-
-
Lehtonen, J.1
Shen, B.2
Vihinen, M.3
Casini, A.4
Scozzafava, A.5
Supuran, C.T.6
-
14
-
-
1342304082
-
Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: Implications for selective inhibition of membrane-associated isozyme
-
Whittington DA, Grubb JH, Waheed A, Shah GN, Sly WS, Christianson DW. Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: Implications for selective inhibition of membrane-associated isozyme. J Biol Chem 2004; 279: 7223-8.
-
(2004)
J Biol Chem
, vol.279
, pp. 7223-7228
-
-
Whittington, D.A.1
Grubb, J.H.2
Waheed, A.3
Shah, G.N.4
Sly, W.S.5
Christianson, D.W.6
-
15
-
-
0030772018
-
Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine
-
Briganti F, Mangani S, Orioli P, Scozzafava A, Vernaglione G, Supuran CT. Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine. Biochemistry 1997; 36: 10384-92.
-
(1997)
Biochemistry
, vol.36
, pp. 10384-10392
-
-
Briganti, F.1
Mangani, S.2
Orioli, P.3
Scozzafava, A.4
Vernaglione, G.5
Supuran, C.T.6
-
16
-
-
0034573012
-
X-ray crystallographic studies of mammalian carbonic anhydrase isozymes
-
New Horizons; Chegwidden W.R, Edwards, Y, Carter, N. Eds, Birkhäuser Verlag;, Basel, pp
-
Stams T, Christianson DW. X-ray crystallographic studies of mammalian carbonic anhydrase isozymes. In The Carbonic Anhydrases - New Horizons; Chegwidden W.R., Edwards, Y., Carter, N. Eds.; Birkhäuser Verlag; 2000, Basel, pp. 159-74.
-
(2000)
The Carbonic Anhydrases
, pp. 159-174
-
-
Stams, T.1
Christianson, D.W.2
-
17
-
-
0344193512
-
-
Casini A, Antel J, Abbate P, Scozzafava A, David S, Waldeck H, et al. Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II, and IV. Bioorg Med Chem Lett 2003; 13: 841-5.
-
Casini A, Antel J, Abbate P, Scozzafava A, David S, Waldeck H, et al. Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II, and IV. Bioorg Med Chem Lett 2003; 13: 841-5.
-
-
-
-
18
-
-
17144375722
-
Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: Solution and X-ray crystallographic studies
-
De Simone G, Di Fiore A, Menchise V, Pedone C, Antel J, Casini A, et al. Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. Bioorg Med Chem Lett 2005; 15: 2315-20.
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 2315-2320
-
-
De Simone, G.1
Di Fiore, A.2
Menchise, V.3
Pedone, C.4
Antel, J.5
Casini, A.6
-
19
-
-
24744467784
-
Carbonic anhydrase inhibitors: Stacking with Phe131 determines active site buiding region of inhibitors as exemplified by the X-ray crystal structure of membrane-impermeant antitumor sulfonamide complexed with isozyme II
-
Menchise V, De Simone G, Alterio V, Di Fiore A, Pedone C, Scozzafava A, et al. Carbonic anhydrase inhibitors: Stacking with Phe131 determines active site buiding region of inhibitors as exemplified by the X-ray crystal structure of membrane-impermeant antitumor sulfonamide complexed with isozyme II. J Med Chem 2005; 48: 5721-7.
-
(2005)
J Med Chem
, vol.48
, pp. 5721-5727
-
-
Menchise, V.1
De Simone, G.2
Alterio, V.3
Di Fiore, A.4
Pedone, C.5
Scozzafava, A.6
-
20
-
-
33745644458
-
Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX
-
Alterio V, Vitale RM, Monti SM, Pedone C, Scozzafava A, Cecchi A, et al. Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX. J Am Chem Soc 2006; 128: 8329-35.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 8329-8335
-
-
Alterio, V.1
Vitale, R.M.2
Monti, S.M.3
Pedone, C.4
Scozzafava, A.5
Cecchi, A.6
-
21
-
-
0346252639
-
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase
-
Abbate F, Winum JY, Potter BV, Casini A, Montero JL, Scozzafava A, et al. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase. Bioorg Med Chem Lett 2004; 14: 231-4.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 231-234
-
-
Abbate, F.1
Winum, J.Y.2
Potter, B.V.3
Casini, A.4
Montero, J.L.5
Scozzafava, A.6
-
22
-
-
33845353402
-
Carbonic anhydrase inhibitors: Clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozymic II, exemplified by the crystal structure of the topiramate sulfamide analogue
-
Winum JY, Temperini C, El Cheikh K, Innocenti A, Vullo D, Ciattini S, et al. Carbonic anhydrase inhibitors: Clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozymic II, exemplified by the crystal structure of the topiramate sulfamide analogue. J Med Chem 2006; 49: 7024-31.
-
(2006)
J Med Chem
, vol.49
, pp. 7024-7031
-
-
Winum, J.Y.1
Temperini, C.2
El Cheikh, K.3
Innocenti, A.4
Vullo, D.5
Ciattini, S.6
-
23
-
-
5144224910
-
Development of sulfonamide carbonic anhydrase inhibitors
-
Supuran, C.T, Scozzafava, A, Conway, J, Eds, CRC Press, Boca Raton FL, USA
-
Supuran CT, Casini A, Scozzafava A. Development of sulfonamide carbonic anhydrase inhibitors. In Carbonic anhydrase - Its inhibitors and activators, Supuran, C.T., Scozzafava, A., Conway, J. (Eds); CRC Press, Boca Raton (FL), USA, 2004, pp. 67-148
-
(2004)
Carbonic anhydrase - Its inhibitors and activators
, pp. 67-148
-
-
Supuran, C.T.1
Casini, A.2
Scozzafava, A.3
-
24
-
-
16544390541
-
Carbonic anhydrases: Current state of the art, therapeutic applications and future prospects
-
Pastorekova S, Parkkila S, Pastorek J, Supuran CT. Carbonic anhydrases: current state of the art, therapeutic applications and future prospects. J Enzyme Inhib Med Chem 2004; 19: 199-229.
-
(2004)
J Enzyme Inhib Med Chem
, vol.19
, pp. 199-229
-
-
Pastorekova, S.1
Parkkila, S.2
Pastorek, J.3
Supuran, C.T.4
-
25
-
-
27944498514
-
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib
-
Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT: Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib. Bioorg Med Chem Lett 2006; 16: 437-42.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 437-442
-
-
Di Fiore, A.1
Pedone, C.2
D'Ambrosio, K.3
Scozzafava, A.4
De Simone, G.5
Supuran, C.T.6
-
26
-
-
0034719437
-
Carbonic anhydrase inhibitors: Synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes
-
Scozzafava A, Briganti F, Ilies MA, Supuran CT: Carbonic anhydrase inhibitors: Synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes. J Med Chem 2000; 43: 292-300.
-
(2000)
J Med Chem
, vol.43
, pp. 292-300
-
-
Scozzafava, A.1
Briganti, F.2
Ilies, M.A.3
Supuran, C.T.4
-
27
-
-
0034676310
-
Carbonic anhydrase inPibitors: Perfluoroalkyl/arylsubstituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged durantion of action
-
Scozzafava A, Menabuoni L, Mincione F, Briganti F, Mincione G, Supuran CT: Carbonic anhydrase inPibitors: perfluoroalkyl/arylsubstituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged durantion of action. J Med Chem 2000; 43: 4542-51.
-
(2000)
J Med Chem
, vol.43
, pp. 4542-4551
-
-
Scozzafava, A.1
Menabuoni, L.2
Mincione, F.3
Briganti, F.4
Mincione, G.5
Supuran, C.T.6
-
28
-
-
0348147633
-
Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX
-
Abbate F, Casini A, Owa T, Scozzafava A, Supuran CT: Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Bioorg Med Chem Lett 2004; 14: 217-23.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 217-223
-
-
Abbate, F.1
Casini, A.2
Owa, T.3
Scozzafava, A.4
Supuran, C.T.5
-
29
-
-
0347360282
-
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride
-
Abbate F, Coetzee A, Casini A, Ciattini S, Scozzafava A, Supuran CT: Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride. Bioorg Med Chem Leo, 2004; 14: 337-41.
-
(2004)
Bioorg Med Chem Leo
, vol.14
, pp. 337-341
-
-
Abbate, F.1
Coetzee, A.2
Casini, A.3
Ciattini, S.4
Scozzafava, A.5
Supuran, C.T.6
-
30
-
-
1642540579
-
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: New pharmacological opportunities due to related binding site recognition
-
Weber A, Casini A, Heine A, Kuhn D, Supuran CT, Scozzafava A, et al. Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: New pharmacological opportunities due to related binding site recognition. J Med Chem 2004; 47: 550-7.
-
J Med Chem 2004; 47: 550-7
-
-
Weber, A.1
Casini, A.2
Heine, A.3
Kuhn, D.4
Supuran, C.T.5
Scozzafava, A.6
-
31
-
-
22744446294
-
Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors
-
Cecchi A, Hulikova A, Pastorek J, Pastorekova S, Scozzafava A, Winum JY, et al. Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors. J Med Chem 2005; 48: 4834-41.
-
(2005)
J Med Chem
, vol.48
, pp. 4834-4841
-
-
Cecchi, A.1
Hulikova, A.2
Pastorek, J.3
Pastorekova, S.4
Scozzafava, A.5
Winum, J.Y.6
-
32
-
-
8844249356
-
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
-
Svastova E, Hulikova A, Rafajova M, Zat'ovicova M, Gibadulinova A, Casini A, et al. Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. FEBS Lett 2004: 577: 439-45.
-
(2004)
FEBS Lett
, vol.577
, pp. 439-445
-
-
Svastova, E.1
Hulikova, A.2
Rafajova, M.3
Zat'ovicova, M.4
Gibadulinova, A.5
Casini, A.6
-
33
-
-
35048900931
-
Saccharin inhibits carbonic anhydrases: Possible explanation for its unpleasant metallic aftertaste
-
Köhler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, et al. Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste. Angew Chem Int Ed Engl 2007; 46: 7697-9
-
(2007)
Angew Chem Int Ed Engl
, vol.46
, pp. 7697-7699
-
-
Köhler, K.1
Hillebrecht, A.2
Schulze Wischeler, J.3
Innocenti, A.4
Heine, A.5
Supuran, C.T.6
-
34
-
-
34547585390
-
Carbonic anhydranse inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: Kinetic and X-ray crystallographic studies
-
Temperini C, Innocenti A, Mastrolorenzo A, Scozzafava A, Supuran CT. Carbonic anhydranse inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: Kinetic and X-ray crystallographic studies. Bioorg Med Chem Lett 2007; 17: 4866-72.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 4866-4872
-
-
Temperini, C.1
Innocenti, A.2
Mastrolorenzo, A.3
Scozzafava, A.4
Supuran, C.T.5
-
35
-
-
0035059355
-
Crystal structure of E. coli β-carbonic anhydrase, an enzyme with an unusual pH-dependent activity
-
Cronk JD, Endrizzi JA, Cronk MR, O'Neill JW, Zhang KYJ. Crystal structure of E. coli β-carbonic anhydrase, an enzyme with an unusual pH-dependent activity. Protein Sci 2001; 10: 911-922.
-
(2001)
Protein Sci
, vol.10
, pp. 911-922
-
-
Cronk, J.D.1
Endrizzi, J.A.2
Cronk, M.R.3
O'Neill, J.W.4
Zhang, K.Y.J.5
-
36
-
-
0034599484
-
The active site architecture of Pisum sativum β-carbonic anhydrase is a mirror image of that of α-carbonic anhydrases
-
Kimber MS, Pai EF. The active site architecture of Pisum sativum β-carbonic anhydrase is a mirror image of that of α-carbonic anhydrases. EMBO J 2000; 19: 2323-2330.
-
(2000)
EMBO J
, vol.19
, pp. 2323-2330
-
-
Kimber, M.S.1
Pai, E.F.2
-
38
-
-
0032717842
-
A plant-type (β-class) carbonic anhydrase in the thermophilic methanoarchaeon Methanobacterium thermoautotrophicum
-
Smith KS, Ferry JG. A plant-type (β-class) carbonic anhydrase in the thermophilic methanoarchaeon Methanobacterium thermoautotrophicum. J Bacteriol 1999; 181: 6247-53.
-
(1999)
J Bacteriol
, vol.181
, pp. 6247-6253
-
-
Smith, K.S.1
Ferry, J.G.2
-
39
-
-
0035971165
-
Crystal structure of the "cab"-type beta class carbonic anhydrase from the archaeon Methanobacterium thermoautotrophicum
-
Strop P, Smith KS, Iverson TM, Ferry JG, Rees DC. Crystal structure of the "cab"-type beta class carbonic anhydrase from the archaeon Methanobacterium thermoautotrophicum. J Biol Chem 2001; 276: 10299-305.
-
(2001)
J Biol Chem
, vol.276
, pp. 10299-10305
-
-
Strop, P.1
Smith, K.S.2
Iverson, T.M.3
Ferry, J.G.4
Rees, D.C.5
-
40
-
-
8844286179
-
Carbonic anhydrase inhibitors. Inhibition of the prokaryotic beta and gamma-class enzymes from Archaea with sulfonamides
-
Zimmerman, S.; Innocenti, A.; Casini, A.; Ferry, J.G.; Scozzafava, A.; Supuran, C.T. Carbonic anhydrase inhibitors. Inhibition of the prokaryotic beta and gamma-class enzymes from Archaea with sulfonamides. Bioorg Med Chem Lett 2004; 14: 6001-6.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 6001-6006
-
-
Zimmerman, S.1
Innocenti, A.2
Casini, A.3
Ferry, J.G.4
Scozzafava, A.5
Supuran, C.T.6
-
42
-
-
34250171776
-
Carbonic anhydrase inhibitors: The beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors
-
Nishimori I, Minakuchi T, Kohsaki T, Onishi S, Takeuchi H, Vullo D, et al. Carbonic anhydrase inhibitors: The beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors. Bioorg Med Chem Lett 2007;17: 3585-94.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 3585-3594
-
-
Nishimori, I.1
Minakuchi, T.2
Kohsaki, T.3
Onishi, S.4
Takeuchi, H.5
Vullo, D.6
-
43
-
-
0029874435
-
A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrases from the archaeon Methanosarcina thermophila
-
Kisker C, Schindelin H, Alber BE, Ferry JG, Rees DC. A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrases from the archaeon Methanosarcina thermophila. EMBO J 1996; 15: 2323-30.
-
(1996)
EMBO J
, vol.15
, pp. 2323-2330
-
-
Kisker, C.1
Schindelin, H.2
Alber, B.E.3
Ferry, J.G.4
Rees, D.C.5
-
44
-
-
0034622579
-
A closer look at the active site of gamma-class carbonic anhydrases: High-resolution crystallograpluc studies of the carbonic anhydrase from Methanosarcina thermophila
-
Iverson TM, Alber BE, Kisker C, Ferry JG Rees DC. A closer look at the active site of gamma-class carbonic anhydrases: High-resolution crystallograpluc studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry 2000; 39: 9222-31.
-
(2000)
Biochemistry
, vol.39
, pp. 9222-9231
-
-
Iverson, T.M.1
Alber, B.E.2
Kisker, C.3
Ferry, J.G.4
Rees, D.C.5
-
45
-
-
2442589472
-
Carbonic anhydrase inhibitors. Inhibition of the zinc and cobalt gamma-class enzyme from the archaeon Methanosarcina thermophila with anions
-
Innocenti A, Zimmerman S, Casini A, Ferry JG, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of the zinc and cobalt gamma-class enzyme from the archaeon Methanosarcina thermophila with anions Bioorg Med Chem Lett 2004; 14: 3327-31.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 3327-3331
-
-
Innocenti, A.1
Zimmerman, S.2
Casini, A.3
Ferry, J.G.4
Scozzafava, A.5
Supuran, C.T.6
-
46
-
-
0034633991
-
The active site structure of Thalassiosira weissflogii carbonic anhydrase 1
-
Cox EH, McLendon GL, Morel FM, Lane TW, Prince RC, Pickering IJ, et al. The active site structure of Thalassiosira weissflogii carbonic anhydrase 1. Biochemistry 2000; 39: 12128-30.
-
(2000)
Biochemistry
, vol.39
, pp. 12128-12130
-
-
Cox, E.H.1
McLendon, G.L.2
Morel, F.M.3
Lane, T.W.4
Prince, R.C.5
Pickering, I.J.6
-
47
-
-
33645402549
-
Carbonic adhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs
-
Nishimori I, Minakuchi T, Morimoto K, Sano S, Onishi S, Takeuchi H, et al. Carbonic adhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. J Med Chem 2006; 49: 2117-26.
-
(2006)
J Med Chem
, vol.49
, pp. 2117-2126
-
-
Nishimori, I.1
Minakuchi, T.2
Morimoto, K.3
Sano, S.4
Onishi, S.5
Takeuchi, H.6
-
48
-
-
33644811878
-
Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacler pylori
-
Nishimori I, Vullo D, Minakuchi T, Morimoto K, Onishi S, Scozzafava A, et al. Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacler pylori. Bioorg Med Chem Lett 2006; 16: 2182-8.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 2182-2188
-
-
Nishimori, I.1
Vullo, D.2
Minakuchi, T.3
Morimoto, K.4
Onishi, S.5
Scozzafava, A.6
-
49
-
-
10444281634
-
-
Krungkrai j, Scozzafava A, Reungprapavut S, Krungkrai SR, Rattanajak R, Kamchonwongpaisan S, et al. Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anbydrase with aromatic sulfonamides: Towards antimalarials with a novel mechanism of action? Bioorg Med Chem 2005; 13: 483-9.
-
Krungkrai j, Scozzafava A, Reungprapavut S, Krungkrai SR, Rattanajak R, Kamchonwongpaisan S, et al. Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anbydrase with aromatic sulfonamides: Towards antimalarials with a novel mechanism of action? Bioorg Med Chem 2005; 13: 483-9.
-
-
-
-
50
-
-
0033044284
-
Role of a novel photosystem II - associated carbonic anhydrase in photosynthetic carbon assimilation in Chlamydomonas reinhardtii
-
Park Y, Karlsson J, Rojdestvenski I, Pronina N, Klimov V, Oquist G, et al. Role of a novel photosystem II - associated carbonic anhydrase in photosynthetic carbon assimilation in Chlamydomonas reinhardtii. FEBS Lett 1999; 444: 102-5.
-
(1999)
FEBS Lett
, vol.444
, pp. 102-105
-
-
Park, Y.1
Karlsson, J.2
Rojdestvenski, I.3
Pronina, N.4
Klimov, V.5
Oquist, G.6
-
51
-
-
0034569944
-
An overview of the distribution and function of carbonic anhydrase in mammals
-
New Horizons, Chegwidden W.R, Edwards, Y, Carter, N. Eds, Birkhäuser Verlag, Basel
-
Parkkila S. An overview of the distribution and function of carbonic anhydrase in mammals. In The Carbonic Anhydrases - New Horizons, Chegwidden W.R., Edwards, Y., Carter, N. Eds.; Birkhäuser Verlag, Basel, 2000, pp. 79-93.
-
(2000)
The Carbonic Anhydrases
, pp. 79-93
-
-
Parkkila, S.1
-
52
-
-
0028111173
-
Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
-
Pastorek J, Pastorekova S, Callebaut I, Mornon JP, Zelnik V, Opavsky R, et al. Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 1994; 9: 2877-88.
-
(1994)
Oncogene
, vol.9
, pp. 2877-2888
-
-
Pastorek, J.1
Pastorekova, S.2
Callebaut, I.3
Mornon, J.P.4
Zelnik, V.5
Opavsky, R.6
-
53
-
-
0028142654
-
Carbonic anhydrase activators. Part 3. Structure-activity correlations for a series of isozyme II activators
-
Clare BW, Supuran CT. Carbonic anhydrase activators. Part 3. Structure-activity correlations for a series of isozyme II activators. J Pharm Sci 1994; 83: 768-79.
-
(1994)
J Pharm Sci
, vol.83
, pp. 768-779
-
-
Clare, B.W.1
Supuran, C.T.2
-
54
-
-
33846283799
-
-
Temperini C, Innocenti A, Scozzafava A, Mastrolorenzo A, Supuran CT. Carbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV. Bioorg Med Chem Lett 2007;17: 628-35
-
Temperini C, Innocenti A, Scozzafava A, Mastrolorenzo A, Supuran CT. Carbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV. Bioorg Med Chem Lett 2007;17: 628-35
-
-
-
-
55
-
-
33749039202
-
-
Temperini C, Scozzafava A, Vullo D, Supuran CT. Carbonic anhydrase activators. Activation of isozymess I, II, IV, VA, VII, and XIV with L- and D-histidine and crystallographic analysis of their adducts with isoform II: Engineering proton-transfer processes within the active site of an enzyme. Chemistry 2006; 12: 7057-66.
-
Temperini C, Scozzafava A, Vullo D, Supuran CT. Carbonic anhydrase activators. Activation of isozymess I, II, IV, VA, VII, and XIV with L- and D-histidine and crystallographic analysis of their adducts with isoform II: Engineering proton-transfer processes within the active site of an enzyme. Chemistry 2006; 12: 7057-66.
-
-
-
-
56
-
-
33646751543
-
-
Temperini C, Scozzafava A, Vullo D, Supuran CT. Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: Stereospecific recognition within the active site of an enzyme and its consequences for the drug design. J Med Chem 2006; 49: 3019-27,
-
Temperini C, Scozzafava A, Vullo D, Supuran CT. Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: Stereospecific recognition within the active site of an enzyme and its consequences for the drug design. J Med Chem 2006; 49: 3019-27,
-
-
-
-
57
-
-
0037156347
-
Carbonic abhydrase activators: Human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1
-
Scozzalava A, Supuran CT. Carbonic abhydrase activators: Human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1. Bioorg Med Chem Lett 2002, 12, 1177-80.
-
(2002)
Bioorg Med Chem Lett
, vol.12
, pp. 1177-1180
-
-
Scozzalava, A.1
Supuran, C.T.2
-
58
-
-
0034569335
-
Activation of carbonic anhydrase isozymes
-
New Horizons; Chegwidden W. R, Carter, N, Edwards, Y, Eds, Birkhauser Verlag: Basel, Switzerland
-
Supuran CT, Scozzafava A. Activation of carbonic anhydrase isozymes. In The Carbonic Anhydrases - New Horizons; Chegwidden W. R., Carter, N., Edwards, Y., Eds.; Birkhauser Verlag: Basel, Switzerland, 2000: 197-219
-
(2000)
The Carbonic Anhydrases
, pp. 197-219
-
-
Supuran, C.T.1
Scozzafava, A.2
-
59
-
-
7044228995
-
Carbonic anhydrase activators
-
Supuran, C. T, Scozzafava, A, Conway, J, Eds, CRC Press: Boca Raton, FL
-
Ilies M, Scozzafava A, Supuran CT. Carbonic anhydrase activators. In Carbonic anhydrase - Its inhibitors and activators; Supuran, C. T., Scozzafava, A., Conway, J., Eds., CRC Press: Boca Raton, FL, 2004: 317-52.
-
(2004)
Carbonic anhydrase - Its inhibitors and activators
, pp. 317-352
-
-
Ilies, M.1
Scozzafava, A.2
Supuran, C.T.3
-
60
-
-
85056062662
-
Carbonic anhydrase activators as potential anti-Alzheimer's disease agents
-
Smith, H. J, Simons, C, Sewell, R. D. E, Eds, CRC Press: Boca Raton, FL
-
Supuran CT, Scozzafava A. Carbonic anhydrase activators as potential anti-Alzheimer's disease agents. In Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies; Smith, H. J., Simons, C., Sewell, R. D. E., Eds.; CRC Press: Boca Raton, FL, 2008, pp. 265-88
-
(2008)
Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies
, pp. 265-288
-
-
Supuran, C.T.1
Scozzafava, A.2
|