Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 5, 2003, Pages 841-845

  Casini, Angela ^a   Antel, Jochen ^b   Abbate, Francesco ^a   Scozzafava, Andrea ^a   David, Samuel ^b   Waldeck, Harald ^b   Schäfer, Siegfried ^b   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Solvay Pharmaceuticals GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; CARBOHYDRATE DERIVATIVE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IV; DICLOFENAMIDE; ETHOXZOLAMIDE; METHAZOLAMIDE; SULFAMIC ACID; SULFANILAMIDE DERIVATIVE; SULFUR DERIVATIVE; TOPIRAMATE; UNCLASSIFIED DRUG; ZINC;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; HYDROGEN BOND; IONIZATION; NONHUMAN; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

EID: 0344193512     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00029-5     Document Type: Article

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