Carbonic anhydrase inhibitors: Synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus cytosolic isozymes

Journal of Medicinal Chemistry

Volumn 43, Issue 2, 2000, Pages 292-300

  Scozzafava, Andrea ^a   Briganti, Fabrizio ^a   Ilies, Marc A ^b   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF AGRONOMIC SCIENCES AND VETERINARY MEDICINE OF BUCHAREST   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; BENZOLAMIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; ETHOXZOLAMIDE; ISOENZYME; METHAZOLAMIDE; SULFANILAMIDE; SULFONAMIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; RAT;

ANIMALS; CARBONIC ANHYDRASE INHIBITORS; CATTLE; CELL MEMBRANE PERMEABILITY; CYTOSOL; ERYTHROCYTE MEMBRANE; HUMANS; ISOENZYMES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, WISTAR; SPECTROPHOTOMETRY, ULTRAVIOLET; SULFONAMIDES;

EID: 0034719437     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990479+     Document Type: Article

References (75)

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