Carbonic anhydrase inhibitors: Perfluoroalkyl/aryl-substituted derivatives of aromatic/heterocyclic sulfonamides as topical intraocular pressure-lowering agents with prolonged duration of action

Journal of Medicinal Chemistry

Volumn 43, Issue 23, 2000, Pages 4542-4551

  Scozzafava, A ^a   Menabuoni, L ^b   Mincione, F ^a   Briganti, F ^a   Mincione, G ^a   Supuran, C T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Ospedale San Giovanni di Dio   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; CARBONATE DEHYDRATASE INHIBITOR; DICLOFENAMIDE; ETHOXZOLAMIDE; METHAZOLAMIDE; PERFLUORO COMPOUND; SULFONAMIDE;

ACID BASE BALANCE; ANIMAL TISSUE; AQUEOUS HUMOR FORMATION; ARTICLE; CHEMICAL REACTION; DERIVATIZATION; HYDROLYSIS; INTRAOCULAR PRESSURE; NONHUMAN; RABBIT; REACTION ANALYSIS; SOLUBILITY;

ADMINISTRATION, TOPICAL; ANIMALS; AQUEOUS HUMOR; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CATTLE; GLAUCOMA; HUMANS; INTRAOCULAR PRESSURE; ISOENZYMES; LUNG; RABBITS; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TISSUE DISTRIBUTION; UVEA;

EID: 0034676310     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000296j     Document Type: Article

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