-
1
-
-
0036197399
-
Genetic diseases of acid-base transporters
-
Alper, S.L. (2002) Genetic diseases of acid-base transporters. Annual Review of Physiology, 64, 899-923.
-
(2002)
Annual Review of Physiology
, vol.64
, pp. 899-923
-
-
Alper, S.L.1
-
2
-
-
0030772018
-
Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine
-
Briganti, F., Mangani, S., Orioli, P., Scozzafava, A., Vernaglione, G. and Supuran, C.T. (1997) Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine. Biochemistry, 36, 10384-10392.
-
(1997)
Biochemistry
, vol.36
, pp. 10384-10392
-
-
Briganti, F.1
Mangani, S.2
Orioli, P.3
Scozzafava, A.4
Vernaglione, G.5
Supuran, C.T.6
-
3
-
-
0001610142
-
A ternary complex of carbonic anhydrase: X-ray crystallographic structure of the adduct of human carbonic anhydrase II with the activator phenylalanine and the inhibitor azide
-
Briganti, F., Iaconi, V., Mangani, S., Orioli, P., Scozzafava, A., Vernaglione, G. and Supuran, C.T. (1998) A ternary complex of carbonic anhydrase: X-ray crystallographic structure of the adduct of human carbonic anhydrase II with the activator phenylalanine and the inhibitor azide. Inorganica Chimica Acta, 275-276, 295-300.
-
(1998)
Inorganica Chimica Acta
, vol.275
, Issue.276
, pp. 295-300
-
-
Briganti, F.1
Iaconi, V.2
Mangani, S.3
Orioli, P.4
Scozzafava, A.5
Vernaglione, G.6
Supuran, C.T.7
-
4
-
-
0033584160
-
Novel carbonic anhydrase isozymes I, II and IV activators incorporating sulfonyl-histamino moieties
-
Briganti, F., Scozzafava, A. and Supuran, C.T. (1999) Novel carbonic anhydrase isozymes I, II and IV activators incorporating sulfonyl-histamino moieties. Bioorganic and Medicinal Chemistry Letters, 9, 2043-2048.
-
(1999)
Bioorganic and Medicinal Chemistry Letters
, vol.9
, pp. 2043-2048
-
-
Briganti, F.1
Scozzafava, A.2
Supuran, C.T.3
-
5
-
-
0000726701
-
Carbonic anhydrase: Evolution of the zinc binding site by nature and by design
-
Christianson, D.W. and Fierke, C.A. (1996) Carbonic anhydrase: evolution of the zinc binding site by nature and by design. Accounts of Chemical Research, 29, 331-339.
-
(1996)
Accounts of Chemical Research
, vol.29
, pp. 331-339
-
-
Christianson, D.W.1
Fierke, C.A.2
-
6
-
-
0028142654
-
Carbonic anhydrase activators. Part 3. Structure- activity correlations for a series of isozyme II activators
-
Clare, B.W. and Supuran, C.T. (1994) Carbonic anhydrase activators. Part 3. Structure- activity correlations for a series of isozyme II activators. Journal of Pharmaceutical Sciences, 83, 768-773.
-
(1994)
Journal of Pharmaceutical Sciences
, vol.83
, pp. 768-773
-
-
Clare, B.W.1
Supuran, C.T.2
-
7
-
-
0033956122
-
Hypothesis: Do voltage-gated Hþ channels in alveolar epithelial cells contribute to CO2 elimination by the lung?
-
De Coursey, T.E. (2000) Hypothesis: do voltage-gated Hþ channels in alveolar epithelial cells contribute to CO2 elimination by the lung? American Journal of Physiology. Cell Physiology, 278, C1-C10.
-
(2000)
American Journal of Physiology. Cell Physiology
, vol.278
, pp. C1-C10
-
-
Coursey, D.T.E.1
-
8
-
-
0028998264
-
Increasing binding constants of ligands to carbonic anhydrase by using “greasy tails”
-
Gao, J.M., Qiao, S. and Whitesides, G.M. (1995) Increasing binding constants of ligands to carbonic anhydrase by using “greasy tails.” Journal of Medicinal Chemistry, 38, 2292-2301.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 2292-2301
-
-
Gao, J.M.1
Qiao, S.2
Whitesides, G.M.3
-
9
-
-
28844487465
-
Expression of carbonic anhydrases II, IV, VII, VIII and XII in rat brain after kainic acid induced status epilepticus
-
Halmi, P., Parkkila, S. and Honkaniemi, J. (2006) Expression of carbonic anhydrases II, IV, VII, VIII and XII in rat brain after kainic acid induced status epilepticus. Neurochemistry International, 48, 24-30.
-
(2006)
Neurochemistry International
, vol.48
, pp. 24-30
-
-
Halmi, P.1
Parkkila, S.2
Honkaniemi, J.3
-
10
-
-
0034576612
-
Evolution and distribution of the carbonic anhydrase gene families
-
Chegwidden, W.R., Edwards, Y. and Carter, N. (Eds.), Birkhäuser Verlag, Basel
-
Hewett-Emmett, D. (2000) Evolution and distribution of the carbonic anhydrase gene families. In The Carbonic Anhydrases-New Horizons, Chegwidden, W.R., Edwards, Y. and Carter, N. (Eds.), Birkhäuser Verlag, Basel, pp. 29-76.
-
(2000)
The Carbonic Anhydrases-New Horizons
, pp. 29-76
-
-
Hewett-Emmett, D.1
-
12
-
-
0030664701
-
Carbonic anhydrase activators. Part 17. Synthesis and activation study of a series of 1-(1,2,4-triazole-(1H)-3-yl)-2,4,6-trisubstituted-pyridinium salts against isozymes I, II and IV
-
Ilies, M.A., Banciu, M.D., Ilies, M., Chiraleu, F., Briganti, F., Scozzafava, A. and Supuran, C.T. (1997) Carbonic anhydrase activators. Part 17. Synthesis and activation study of a series of 1-(1,2,4-triazole-(1H)-3-yl)-2,4,6-trisubstituted-pyridinium salts against isozymes I, II and IV. European Journal of Medicinal Chemistry, 32, 911-918.
-
(1997)
European Journal of Medicinal Chemistry
, vol.32
, pp. 911-918
-
-
Ilies, M.A.1
Banciu, M.D.2
Ilies, M.3
Chiraleu, F.4
Briganti, F.5
Scozzafava, A.6
Supuran, C.T.7
-
13
-
-
0037122755
-
Carbonic anhydrase activators: Design of high affinity isozymes I, II, and IV activators, incorporating tri-=tetrasubstituted-pyridinium-azole moieties
-
Ilies, M., Banciu, M.D., Ilies, M.A., Scozzafava, A., Caproiu, M.T. and Supuran, C.T. (2002) Carbonic anhydrase activators: design of high affinity isozymes I, II, and IV activators, incorporating tri-=tetrasubstituted-pyridinium-azole moieties. Journal of Medicinal Chemistry, 45, 504-510.
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, pp. 504-510
-
-
Ilies, M.1
Banciu, M.D.2
Ilies, M.A.3
Scozzafava, A.4
Caproiu, M.T.5
Supuran, C.T.6
-
14
-
-
7044228995
-
Carbonic anhydrase activators
-
Supuran, C.T., Scozzafava, A. and Conway, J. (Eds.) CRC Press, Boca Raton 2004
-
Ilies, M., Scozzafava, A. and Supuran, C.T. (2004) Carbonic anhydrase activators. In Carbonic Anhydrase-Its Inhibitors and Activators, Supuran, C.T., Scozzafava, A. and Conway, J. (Eds.) CRC Press, Boca Raton 2004, pp. 317-352.
-
(2004)
Carbonic Anhydrase-Its Inhibitors and Activators
, pp. 317-352
-
-
Ilies, M.1
Scozzafava, A.2
Supuran, C.T.3
-
15
-
-
0015239422
-
The carbonic dioxide hydration activity of carbonic anhydrase
-
Khalifah, R.G. (1971) The carbonic dioxide hydration activity of carbonic anhydrase. Journal of Biological Chemistry, 246, 2561-2573.
-
(1971)
Journal of Biological Chemistry
, vol.246
, pp. 2561-2573
-
-
Khalifah, R.G.1
-
16
-
-
0001724142
-
Das Ferment Kohlensäureanhydrase in Tierkörper
-
Leiner, M. (1940) Das Ferment Kohlensäureanhydrase in Tierkörper. Naturwiss, 28, 316-317.
-
(1940)
Naturwiss
, vol.28
, pp. 316-317
-
-
Leiner, M.1
-
17
-
-
0001176531
-
Sulphanilamide as a specific inhibitor of carbonic anhydrase
-
Mann, T. and Keilin, D. (1940) Sulphanilamide as a specific inhibitor of carbonic anhydrase. Nature, 146, 164-165.
-
(1940)
Nature
, vol.146
, pp. 164-165
-
-
Mann, T.1
Keilin, D.2
-
18
-
-
0021181568
-
Neurochemical enzyme changes in Alzheimer’s disease and Pick’s disease
-
Meyer-Ruge, W., Iwangoff, P. and Reichlmeier, K. (1984) Neurochemical enzyme changes in Alzheimer’s disease and Pick’s disease. Archives of Gerontology and Geriatrics, 3, 161-165.
-
(1984)
Archives of Gerontology and Geriatrics
, vol.3
, pp. 161-165
-
-
Meyer-Ruge, W.1
Iwangoff, P.2
Reichlmeier, K.3
-
19
-
-
0009593678
-
Unexpected pH-dependent conformation of His-64, the proton shuttle of carbonic anhydrase II
-
Nair, S.K. and Christianson, D.W. (1991) Unexpected pH-dependent conformation of His-64, the proton shuttle of carbonic anhydrase II. Journal of American Chemical Society, 113, 9455-9458.
-
(1991)
Journal of American Chemical Society
, vol.113
, pp. 9455-9458
-
-
Nair, S.K.1
Christianson, D.W.2
-
20
-
-
0004164846
-
-
Royal Society of Chemistry, London
-
Page, M.I. and Williams, A. (1989) Enzyme Mechanism, Royal Society of Chemistry, London, pp. 1-13.
-
(1989)
Enzyme Mechanism
, pp. 1-13
-
-
Page, M.I.1
Williams, A.2
-
21
-
-
0024850617
-
Enhancement of carbonic anhydrase activity by erythrocyte membrane
-
Parkes, J.L. and Coleman, P. (1989) Enhancement of carbonic anhydrase activity by erythrocyte membrane. Archives of Biochemistry and Biophysics, 275, 459-468.
-
(1989)
Archives of Biochemistry and Biophysics
, vol.275
, pp. 459-468
-
-
Parkes, J.L.1
Coleman, P.2
-
22
-
-
0011800420
-
Carbonic anhydrase inhibitors. Part 3. Relations between chemical structure of inhibitors and activators
-
Puscas, I., Supuran, C.T. and Manole, G. (1990) Carbonic anhydrase inhibitors. Part 3. Relations between chemical structure of inhibitors and activators. Revue Roumaine de Chimie, 35, 683-689.
-
(1990)
Revue Roumaine de Chimie
, vol.35
, pp. 683-689
-
-
Puscas, I.1
Supuran, C.T.2
Manole, G.3
-
23
-
-
85056033597
-
Carbonic anhydrase activators. Part 9. Kinetic parameters for isozyme II activation by histamine prove a non-competitive type of interaction
-
Puscas, I., Coltau, M., Puscas, I.C. and Supuran, C.T. (1994) Carbonic anhydrase activators. Part 9. Kinetic parameters for isozyme II activation by histamine prove a non-competitive type of interaction. Revue Roumaine de Chimie, 39, 114-119.
-
(1994)
Revue Roumaine de Chimie
, vol.39
, pp. 114-119
-
-
Puscas, I.1
Coltau, M.2
Puscas, I.C.3
Supuran, C.T.4
-
24
-
-
1542475199
-
Carbonic anhydrase activators. Part 10. Kinetic studies of isozyme II activation with pentagastrin
-
Puscas, I., Coltau, M., Supuran, C.T., Moisi, F., Lazoc, L. and Farcau, D. (1996) Carbonic anhydrase activators. Part 10. Kinetic studies of isozyme II activation with pentagastrin. Revue Roumaine de Chimie, 41, 159-163.
-
(1996)
Revue Roumaine de Chimie
, vol.41
, pp. 159-163
-
-
Puscas, I.1
Coltau, M.2
Supuran, C.T.3
Moisi, F.4
Lazoc, L.5
Farcau, D.6
-
25
-
-
0027006712
-
Carnosine: Its properties, functions and potential therapeutic applications
-
Quinn, P.J., Boldyrev, A.A. and Formazuyk, V.E. (1992) Carnosine: its properties, functions and potential therapeutic applications. Molecular Aspects of Medicine, 13, 379-444.
-
(1992)
Molecular Aspects of Medicine
, vol.13
, pp. 379-444
-
-
Quinn, P.J.1
Boldyrev, A.A.2
Formazuyk, V.E.3
-
26
-
-
0035049245
-
A membrane metabolon linking carbonic anhydrase with chloride= bicarbonate anion exchangers
-
Reithmeier, R.A. (2001) A membrane metabolon linking carbonic anhydrase with chloride= bicarbonate anion exchangers. Blood Cells, Molecules and Diseases, 27, 85-89.
-
(2001)
Blood Cells, Molecules and Diseases
, vol.27
, pp. 85-89
-
-
Reithmeier, R.A.1
-
27
-
-
0026501234
-
Molecular basis of human carbonic anhydrase II deficiency
-
Roth, D.E., Venta, P.J., Tashian, R.E. and Sly, W.S. (1992) Molecular basis of human carbonic anhydrase II deficiency. Proceedings of the National Academy of Sciences of the United States of America, 89, 1804-1808.
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, pp. 1804-1808
-
-
Roth, D.E.1
Venta, P.J.2
Tashian, R.E.3
Sly, W.S.4
-
28
-
-
0036211754
-
Osteoclastic acidification pathways during bone resorption
-
Rousselle, A.-V. and Heymann, D. (2002) Osteoclastic acidification pathways during bone resorption. Bone, 30, 533-540.
-
(2002)
Bone
, vol.30
, pp. 533-540
-
-
Rousselle, A.-V.1
Heymann, D.2
-
29
-
-
0034008535
-
Carbonic anhydrase activators. Part 21. Novel activators of isozymes I, II and IV incorporating carboxamido and ureido histamine moieties
-
Scozzafava, A. and Supuran, C.T. (2000a) Carbonic anhydrase activators. Part 21. Novel activators of isozymes I, II and IV incorporating carboxamido and ureido histamine moieties. European Journal of Medicinal Chemistry, 35, 31-39.
-
(2000)
European Journal of Medicinal Chemistry
, vol.35
, pp. 31-39
-
-
Scozzafava, A.1
Supuran, C.T.2
-
30
-
-
0034047082
-
Carbonic anhydrase activators. Part 24. High affinity isozymes I, II and IV activators, derivatives of 4-(4-chlorophenylsulfonylureido- amino acyl)ethyl-1H-imidazole
-
Scozzafava, A. and Supuran, C.T. (2000b) Carbonic anhydrase activators. Part 24. High affinity isozymes I, II and IV activators, derivatives of 4-(4-chlorophenylsulfonylureido- amino acyl)ethyl-1H-imidazole. European Journal of Pharmaceutical Sciences, 10, 29-41.
-
(2000)
European Journal of Pharmaceutical Sciences
, vol.10
, pp. 29-41
-
-
Scozzafava, A.1
Supuran, C.T.2
-
31
-
-
0037156347
-
Carbonic anhydrase activators: Human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1
-
Scozzafava, A. and Supuran, C.T. (2002a) Carbonic anhydrase activators: human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1. Bioorganic Medicinal Chemistry Letters, 12, 1177-1180.
-
(2002)
Bioorganic Medicinal Chemistry Letters
, vol.12
, pp. 1177-1180
-
-
Scozzafava, A.1
Supuran, C.T.2
-
32
-
-
0037122754
-
Carbonic anhydrase activators: High affinity isozymes I, II, and IV activators, incorporating a b-alanyl-histidine scaffold
-
Scozzafava, A. and Supuran, C.T. (2002b) Carbonic anhydrase activators: high affinity isozymes I, II, and IV activators, incorporating a b-alanyl-histidine scaffold. Journal of Medicinal Chemistry, 45, 284-291
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, pp. 284-291
-
-
Scozzafava, A.1
Supuran, C.T.2
-
33
-
-
0033566151
-
Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective intraocular pressure lowering aromatic=heterocyclic sulfonamides containing cationic or anionic moieties. Is the tail more important than the ring?
-
Scozzafava, A., Menabuoni, L., Mincione, F., Briganti, F., Mincione, G. and Supuran, C.T. (1999) Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective intraocular pressure lowering aromatic=heterocyclic sulfonamides containing cationic or anionic moieties. Is the tail more important than the ring? Journal of Medicinal Chemistry, 42, 2641-2650.
-
(1999)
Journal of Medicinal Chemistry
, vol.42
, pp. 2641-2650
-
-
Scozzafava, A.1
Menabuoni, L.2
Mincione, F.3
Briganti, F.4
Mincione, G.5
Supuran, C.T.6
-
34
-
-
0034719437
-
Carbonic anhydrase inhibitors. Synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus the cytosolic isozymes
-
Scozzafava, A., Briganti, F., Ilies, M.A. and Supuran, C.T. (2000a) Carbonic anhydrase inhibitors. Synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus the cytosolic isozymes. Journal of Medicinal Chemistry, 43, 292-300.
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, pp. 292-300
-
-
Scozzafava, A.1
Briganti, F.2
Ilies, M.A.3
Supuran, C.T.4
-
35
-
-
0034009801
-
Carbonic anhydrase activators: Synthesis of high affinity isozymes I, II and IV activators, derivatives of 4-(4-tosylureido-amino acyl)ethyl-1H-imidazole (histamine derivatives)
-
Scozzafava, A., Iorga, B. and Supuran, C.T. (2000b) Carbonic anhydrase activators: synthesis of high affinity isozymes I, II and IV activators, derivatives of 4-(4-tosylureido-amino acyl)ethyl-1H-imidazole (histamine derivatives). Journal of Enzyme Inhibition, 15, 139-161.
-
(2000)
Journal of Enzyme Inhibition
, vol.15
, pp. 139-161
-
-
Scozzafava, A.1
Iorga, B.2
Supuran, C.T.3
-
37
-
-
0034573012
-
X-ray crystallographic studies of mammalian carbonic anhydrase isozymes
-
Chegwidden, W.R., Edwards, Y. and Carter, N. (Eds.), Birkhäuser Verlag, Basel, and references cited therein
-
Stams, T. and Christianson, D.W. (2000) X-ray crystallographic studies of mammalian carbonic anhydrase isozymes. In The Carbonic Anhydrases-New Horizons, Chegwidden, W.R., Edwards, Y. and Carter, N. (Eds.), Birkhäuser Verlag, Basel, pp. 159-174, and references cited therein.
-
(2000)
The Carbonic Anhydrases-New Horizons
, pp. 159-174
-
-
Stams, T.1
Christianson, D.W.2
-
38
-
-
0342468068
-
Pharmacological enhancement of synaptic efficacy, spatial learning and memory through carbonic anhydrase activation in rats
-
Sun, M.-K. and Alkon, D.L. (2001) Pharmacological enhancement of synaptic efficacy, spatial learning and memory through carbonic anhydrase activation in rats. Journal of Pharmacology and Experimental Therapeutics, 297, 961-967.
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.297
, pp. 961-967
-
-
Sun, M.-K.1
Alkon, D.L.2
-
39
-
-
0036468837
-
Carbonic anhydrase gating of attention: Memory therapy and enhancement
-
Sun, M.-K. and Alkon, D.L. (2002) Carbonic anhydrase gating of attention: memory therapy and enhancement. Trends in Pharmacological Sciences, 23, 83-89.
-
(2002)
Trends in Pharmacological Sciences
, vol.23
, pp. 83-89
-
-
Sun, M.-K.1
Alkon, D.L.2
-
40
-
-
0035120032
-
Heterosynaptic transformation of GABAergic gating in the hippocampus and effects of carbonic anhydrase inhibition
-
Sun, M.K., Dahl, D. and Alkon, D.L. (2001) Heterosynaptic transformation of GABAergic gating in the hippocampus and effects of carbonic anhydrase inhibition. Journal of Pharmacology and Experimental Therapeutics, 296, 811-817.
-
(2001)
Journal of Pharmacology and Experimental Therapeutics
, vol.296
, pp. 811-817
-
-
Sun, M.K.1
Dahl, D.2
Alkon, D.L.3
-
41
-
-
0011801688
-
Carbonic anhydrase activators. Part 4. A general mechanism of action for activators of isozymes I, II and III
-
Supuran, C.T. (1992) Carbonic anhydrase activators. Part 4. A general mechanism of action for activators of isozymes I, II and III. Revue Roumaine de Chimie, 37, 411-421.
-
(1992)
Revue Roumaine de Chimie
, vol.37
, pp. 411-421
-
-
Supuran, C.T.1
-
42
-
-
0007887046
-
Carbonic anhydrase activators. Part 8. pKa-activation relationship in a series of amino acid derivatives activators of isozyme II
-
Supuran, C.T. and Balaban, A.T. (1994) Carbonic anhydrase activators. Part 8. pKa-activation relationship in a series of amino acid derivatives activators of isozyme II. Revue Roumaine de Chimie, 39, 107-113.
-
(1994)
Revue Roumaine de Chimie
, vol.39
, pp. 107-113
-
-
Supuran, C.T.1
Balaban, A.T.2
-
43
-
-
0041080831
-
Carbonic anhydrase activators
-
Puscas, I. (Ed.), Helicon, Timisoara
-
Supuran, C.T. and Puscas, I. (1994) Carbonic anhydrase activators. In Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism, Puscas, I. (Ed.), Helicon, Timisoara, pp. 113-145.
-
(1994)
Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism
, pp. 113-145
-
-
Supuran, C.T.1
Puscas, I.2
-
44
-
-
85056040913
-
Carbonic anhydrase activators. Part 23. Aminoacyl= dipeptidyl histamine derivatives bind with high affinity to isozymes I, II and IV and act as efficient activators
-
Supuran, C.T. and Scozzafava, A. (1999) Carbonic anhydrase activators. Part 23. Aminoacyl= dipeptidyl histamine derivatives bind with high affinity to isozymes I, II and IV and act as efficient activators. Bioorganic Medicinal Chemistry, 7, 2397-2406.
-
(1999)
Bioorganic Medicinal Chemistry
, vol.7
, pp. 2397-2406
-
-
Supuran, C.T.1
Scozzafava, A.2
-
45
-
-
0034569335
-
Activation of carbonic anhydrase isozymes
-
Chegwidden, W.R., Edwards, Y. and Carter, N. (Eds.), Birkhäuser Verlag, Basel
-
Supuran, C.T. and Scozzafava, A. (2000a) Activation of carbonic anhydrase isozymes. In The Carbonic Anhydrases-New Horizons, Chegwidden, W.R., Edwards, Y. and Carter, N. (Eds.), Birkhäuser Verlag, Basel, pp. 197-219.
-
(2000)
The Carbonic Anhydrases-New Horizons
, pp. 197-219
-
-
Supuran, C.T.1
Scozzafava, A.2
-
47
-
-
0033872086
-
Carbonic anhydrase activators. Synthesis oh high affinity isozymes I, II and IV activators, derivatives of 4-(arylsulfonylureido-amino acyl)ethyl-1H-imidazole
-
Supuran, C.T. and Scozzafava, A. (2000c) Carbonic anhydrase activators. Synthesis oh high affinity isozymes I, II and IV activators, derivatives of 4-(arylsulfonylureido-amino acyl)ethyl-1H-imidazole. Journal of Enzyme Inhibition, 15, 471-486.
-
(2000)
Journal of Enzyme Inhibition
, vol.15
, pp. 471-486
-
-
Supuran, C.T.1
Scozzafava, A.2
-
48
-
-
0002444775
-
Carbonic anhydrase inhibitors
-
Supuran, C.T. and Scozzafava, A. (2001) Carbonic anhydrase inhibitors. Current Medicinal Chemistry-Immunologic, Endocrine and Metabolic Agents, 1, 61-97.
-
(2001)
Current Medicinal Chemistry-Immunologic, Endocrine and Metabolic Agents
, vol.1
, pp. 61-97
-
-
Supuran, C.T.1
Scozzafava, A.2
-
49
-
-
0347101636
-
Carbonic anhydrase activators. Part 2. Amino acids and some of their derivatives may act as potent enzyme activators
-
Supuran, C.T., Dinculescu, A., Manole, G., Savan, F., Puscas, I. and Balaban, A.T. (1991) Carbonic anhydrase activators. Part 2. Amino acids and some of their derivatives may act as potent enzyme activators. Revue Roumaine de Chimie, 36, 937-946.
-
(1991)
Revue Roumaine de Chimie
, vol.36
, pp. 937-946
-
-
Supuran, C.T.1
Dinculescu, A.2
Manole, G.3
Savan, F.4
Puscas, I.5
Balaban, A.T.6
-
50
-
-
0027745222
-
Carbonic anhydrase activators. Part 7. Isozyme II activation with bis-azolylmethanes,- ethanes and related azoles
-
Supuran, C.T., Balaban, A.T., Cabildo, P., Claramunt, R.M., Lavandera, J.L. and Elguero, J. (1993a) Carbonic anhydrase activators. Part 7. Isozyme II activation with bis-azolylmethanes,- ethanes and related azoles. Biological and Pharmaceutical Bulletin, 16, 1236-1239.
-
(1993)
Biological and Pharmaceutical Bulletin
, vol.16
, pp. 1236-1239
-
-
Supuran, C.T.1
Balaban, A.T.2
Cabildo, P.3
Claramunt, R.M.4
Lavandera, J.L.5
Elguero, J.6
-
51
-
-
0342680993
-
Carbonic anhydrase activators. Part 5. CA II activation by 2,4,6-trisubstituted pyridinium cations with 1-(v-aminoalkyl)side chains
-
Supuran, C.T., Dinculescu, A. and Balaban, A.T. (1993b) Carbonic anhydrase activators. Part 5. CA II activation by 2,4,6-trisubstituted pyridinium cations with 1-(v-aminoalkyl)side chains. Revue Roumaine de Chimie, 38, 343-349.
-
(1993)
Revue Roumaine de Chimie
, vol.38
, pp. 343-349
-
-
Supuran, C.T.1
Dinculescu, A.2
Balaban, A.T.3
-
52
-
-
0029788683
-
Carbonic anhydrase activators. Part 14. Synthesis of mono- and bis-pyridinium salt derivatives of 2-amino-5-(2-aminoethyl)- and 2-amino-5-(3-aminopropyl)-1,3,4-thiadiazole, and their interaction with isozyme II
-
Supuran, C.T., Barboiu, M., Luca, C., Pop, E., Brewster, M.E. and Dinculescu, A. (1996a) Carbonic anhydrase activators. Part 14. Synthesis of mono- and bis-pyridinium salt derivatives of 2-amino-5-(2-aminoethyl)- and 2-amino-5-(3-aminopropyl)-1,3,4-thiadiazole, and their interaction with isozyme II. European Journal of Medicinal Chemistry, 31, 597-606.
-
(1996)
European Journal of Medicinal Chemistry
, vol.31
, pp. 597-606
-
-
Supuran, C.T.1
Barboiu, M.2
Luca, C.3
Pop, E.4
Brewster, M.E.5
Dinculescu, A.6
-
53
-
-
0029824776
-
Carbonic anhydrase activators. Part 15. A kinetic study of the interaction of bovine isozyme II with pyrazoles, bis- and tris-azolylmethanes
-
Supuran, C.T., Claramunt, R.M., Lavandera, J.L. and Elguero, J. (1996b) Carbonic anhydrase activators. Part 15. A kinetic study of the interaction of bovine isozyme II with pyrazoles, bis- and tris-azolylmethanes. Biological and Pharmaceutical Bulletin, 19, 1417-1422.
-
(1996)
Biological and Pharmaceutical Bulletin
, vol.19
, pp. 1417-1422
-
-
Supuran, C.T.1
Claramunt, R.M.2
Lavandera, J.L.3
Elguero, J.4
-
54
-
-
0032122565
-
Carbonic anhydrase inhibitors. Part 53. Synthesis of substitutedpyridinium derivatives of aromatic sulfonamides: The first non polymeric membraneimpermeable inhibitors with selectivity for isozyme IV
-
Supuran, C.T., Scozzafava, A., Ilies, M.A., Iorga, B., Cristea, T., Briganti, F., Chiraleu, F. and Banciu, M.D. (1998) Carbonic anhydrase inhibitors. Part 53. Synthesis of substitutedpyridinium derivatives of aromatic sulfonamides: The first non polymeric membraneimpermeable inhibitors with selectivity for isozyme IV. European Journal of Medicinal Chemistry, 33, 577-594.
-
(1998)
European Journal of Medicinal Chemistry
, vol.33
, pp. 577-594
-
-
Supuran, C.T.1
Scozzafava, A.2
Ilies, M.A.3
Iorga, B.4
Cristea, T.5
Briganti, F.6
Chiraleu, F.7
Banciu, M.D.8
-
55
-
-
0037369153
-
Carbonic anhydrase inhibitors
-
Supuran, C.T., Scozzafava, A. and Casini, A. (2003) Carbonic anhydrase inhibitors. Medicinal Research Reviews, 23, 146-189.
-
(2003)
Medicinal Research Reviews
, vol.23
, pp. 146-189
-
-
Supuran, C.T.1
Scozzafava, A.2
Casini, A.3
-
56
-
-
1242303231
-
-
CRC Press, Boca Raton
-
Supuran, C.T., Scozzafava, A. and Conway, J. (Eds.). (2004) Carbonic Anhydrase-Its Inhibitors and Activators, CRC Press, Boca Raton, pp. 1-368.
-
(2004)
Carbonic Anhydrase-Its Inhibitors and Activators
, pp. 1-368
-
-
Supuran, C.T.1
Scozzafava, A.2
Conway, J.3
-
57
-
-
26844500569
-
Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators
-
Temperini, C., Scozzafava, A., Puccetti, L. and Supuran, C.T. (2005) Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators. Bioorganic and Medicinal Chemistry Letters, 15, 5136-5141.
-
(2005)
Bioorganic and Medicinal Chemistry Letters
, vol.15
, pp. 5136-5141
-
-
Temperini, C.1
Scozzafava, A.2
Puccetti, L.3
Supuran, C.T.4
-
58
-
-
33749039202
-
Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with L- and D-histidine and crystallographic analysis of their adducts with isoform II: Engineering protontransfer processes within the active site of an enzyme
-
Temperini, C., Scozzafava, A., Vullo, D. and Supuran, C.T. (2006a) Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with L- and D-histidine and crystallographic analysis of their adducts with isoform II: engineering protontransfer processes within the active site of an enzyme. Chemistry, 12, 7057-7066.
-
(2006)
Chemistry
, vol.12
, pp. 7057-7066
-
-
Temperini, C.1
Scozzafava, A.2
Vullo, D.3
Supuran, C.T.4
-
59
-
-
33646751543
-
Carbonic nhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: Stereospecific recognition within the active site of an enzyme and its consequences for the drug design
-
Temperini, C., Scozzafava, A., Vullo, D. and Supuran, C.T. (2006b) Carbonic nhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design. Journal of Medicinal Chemistry, 49, 3019-3027.
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, pp. 3019-3027
-
-
Temperini, C.1
Scozzafava, A.2
Vullo, D.3
Supuran, C.T.4
-
60
-
-
33747520016
-
Carbonic anhydrase activators. The first X-ray crystallographic study of an adduct of isoform I
-
Temperini, C., Scozzafava, A. and Supuran, C.T. (2006c) Carbonic anhydrase activators. The first X-ray crystallographic study of an adduct of isoform I. Bioorganic and Medicinal Chemistry Letters, 16, 5152-5156.
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, pp. 5152-5156
-
-
Temperini, C.1
Scozzafava, A.2
Supuran, C.T.3
-
61
-
-
0034625056
-
Identification of the carbonic anhydrase II binding site in the Cl_=HCO3_ anion exchanger AE1
-
Vince, J.W. and Reithmeier, R.A. (2000) Identification of the carbonic anhydrase II binding site in the Cl_=HCO3_ anion exchanger AE1. Biochemistry, 39, 5527-5533.
-
(2000)
Biochemistry
, vol.39
, pp. 5527-5533
-
-
Vince, J.W.1
Reithmeier, R.A.2
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