Carbonic anhydrase inhibitors: The β-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 13, 2007, Pages 3585-3594

  Nishimori, Isao ^a   Minakuchi, Tomoko ^a   Kohsaki, Takuhiro ^a   Onishi, Saburo ^a   Takeuchi, Hiroaki ^a   Vullo, Daniela ^b   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

class enzyme; Carbonic anhydrase; Catalytic inhibition mechanism; Enzyme inhibitor; Helicobacter pylori; Sulfamate; Sulfonamide

Indexed keywords

ACETAZOLAMIDE; AMINO ACID; BETA CARBONIC ANHYDRASE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; ETHOXZOLAMIDE; SULFONAMIDE; SULPIRIDE; TOPIRAMATE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; DRUG TARGETING; ENZYME INHIBITION; ENZYME PURIFICATION; HELICOBACTER PYLORI; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN TARGETING;

AMINO ACID SEQUENCE; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CHEMISTRY, PHARMACEUTICAL; CLONING, MOLECULAR; DRUG DESIGN; ENZYME INHIBITORS; HELICOBACTER PYLORI; HUMANS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STOMACH NEOPLASMS; STOMACH ULCER; SULFONAMIDES;

BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI;

EID: 34250171776     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.063     Document Type: Article

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