Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: Towards antimalarials with a novel mechanism of action?

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 2, 2005, Pages 483-489

  Krungkrai, Jerapan ^a   Scozzafava, Andrea ^b   Reungprapavut, Sutarnthip ^c   Krungkrai, Sudaratana R ^c   Rattanajak, Roonglawan ^d   Kamchonwongpaisan, Sumalee ^d   Supuran, Claudiu T ^b  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b UNIVERSITY OF FLORENCE   (Italy)

^c RANGSIT UNIVERSITY   (Thailand)

^d NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3,4 DICHLOROPHENYLUREIDOETHYL)BENZENESULFONAMIDE; ACETAZOLAMIDE; ALDEHYDE DERIVATIVE; ANTIMALARIAL AGENT; AROMATIC COMPOUND; CARBAMATE KINASE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; MAFENIDE; PYRIMIDINE DERIVATIVE; SCHIFF BASE; SULFANILAMIDE DERIVATIVE; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG UTILIZATION; ENZYME INHIBITION; GROWTH; HOST; IC 50; IN VITRO STUDY; INHIBITION KINETICS; LIFE CYCLE; LIPOPHILICITY; NONHUMAN; PARASITE; PLASMODIUM FALCIPARUM; PROTOZOON; SYNTHESIS;

ANIMALS; ANTIMALARIALS; CARBONIC ANHYDRASE INHIBITORS; ERYTHROCYTES; HUMANS; MOLECULAR STRUCTURE; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

PLASMODIUM FALCIPARUM;

EID: 10444281634     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.10.015     Document Type: Article

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