What will whole genome searches for susceptibility genes for common complex disease offer to clinical practice?

Journal of Internal Medicine

Volumn 263, Issue 1, 2008, Pages 16-27

  Lango, H ^a   Weedon, M N ^a  

^a PENINSULA MEDICAL SCHOOL   (United Kingdom)

Author keywords

Common genetic susceptibility variants; Complex disease; Genetics; Genome wide association; Polygenic

Indexed keywords

C REACTIVE PROTEIN;

ALLELE; AREA UNDER THE CURVE; BIPOLAR DISORDER; BODY MASS; CANCER; CLINICAL PRACTICE; CORONARY ARTERY DISEASE; CROHN DISEASE; DISEASE PREDISPOSITION; ENVIRONMENTAL FACTOR; GENE EXPRESSION; GENE MAPPING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME; GENOTYPE; HEART INFARCTION; HOMOZYGOSITY; HUMAN; HYPERTENSION; INSULIN DEPENDENT DIABETES MELLITUS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PATHOPHYSIOLOGY; PHARMACOGENETICS; PRIORITY JOURNAL; PROSTATE CANCER; RETINA MACULA AGE RELATED DEGENERATION; REVIEW; RHEUMATOID ARTHRITIS; ROC CURVE; SMOKING; STATISTICAL SIGNIFICANCE; TUMOR SUPPRESSOR GENE;

DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; HUMANS; MALE; MULTIFACTORIAL INHERITANCE; OBESITY; PEDIGREE; PHARMACOGENETICS; POLYMORPHISM, SINGLE NUCLEOTIDE; VARIATION (GENETICS);

EID: 36949022443     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2007.01895.x     Document Type: Review

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