Zn2+ interaction with Alzheimer amyloid β protein calcium channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 4, 1996, Pages 1710-1715

  Arispe, Nelson ^a   Pollard, Harvey B ^a   Rojas, Eduardo ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Giant amyloid protein channel; Lipid bilayer; Zinc blockade; Zinc binding motif

Indexed keywords

1,10 PHENANTHROLINE; 1,10-PHENANTHROLINE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; PEPTIDE FRAGMENT; PHENANTHROLINE DERIVATIVE; ZINC; PHOSPHOLIPID;

ARTICLE; CHANNEL GATING; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; HUMAN; MACROMOLECULE; METABOLISM; PROTEIN TERTIARY STRUCTURE; ALZHEIMER DISEASE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DEMENTIA; HUMAN CELL; ION CONDUCTANCE; LIPID BILAYER; MEMBRANE CHANNEL; MOLECULAR MODEL; NEUROTOXICITY; PRIORITY JOURNAL;

AMYLOID BETA-PROTEIN; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; ION CHANNEL GATING; MACROMOLECULAR SUBSTANCES; PEPTIDE FRAGMENTS; PHENANTHROLINES; PROTEIN STRUCTURE, TERTIARY; ZINC;

EID: 0029670048     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.4.1710     Document Type: Article

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