Amyloid β protein 42(43) in cerebrospinal fluid of patients with Alzheimer's disease

Journal of the Neurological Sciences

Volumn 148, Issue 1, 1997, Pages 41-45

  Tamaoka, Akira ^a   Sawamura, Naoya ^a   Fukushima, Tetsuo ^a   Shoji, Shin'ichi ^a   Matsubara, Etsuro ^b   Shoji, Mikio ^b   Hirai, Shunsaku ^b   Furiya, Yoshiko ^c   Endoh, Riuko ^c   Mori, Hiroshi ^c  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Alzheimer's disease; amyloid protein; cerebrospinal fluid; enzyme linked immunosorbent assay

Indexed keywords

AMYLOID BETA PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN PROCESSING;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MIDDLE AGED; PEPTIDE FRAGMENTS; SEX FACTORS;

EID: 0031149062     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(96)00314-0     Document Type: Article

References (37)

1. Arai, H., Terajima, M., Miura, M., Higuchi, S., Muramatsu, T., Machida, N., Seiki, H., Takase, S., Clark, C.M., Lee, V.M.-Y., Trojanowski, J.Q. and Sasaki, H. (1995) Tau in cerebrospinal fluid: a potential diagnostic marker in Alzheimer's disease. Ann. Neurol., 38: 649-652.
2. Asami-Odaka, A., Ishibashi, Y., Kikuchi, T., Kitada, C. and Suzuki, N. (1995) Long amyloid β-protein secreted from wild-type human neuroblastoma IMR-32 cells. Biochemistry, 34: 10272-10278.
3. Cai, D.X., Golde, T.E. and Younkin, S.G. (1993) Release of excess amyloid β protein from a mutant amyloid β protein precursor. Science, 259: 514-516.
4. Citron, M., Oltersdorf, T., Haass, C., McConlogue, L., Hung, A.Y., Seubert, P., Vigo-Pelfrey, C., Lieberburg, I. and Selkoe, D.J. (1992) Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production. Nature, 360: 672-674.
5. de la Monte, S.M., Volicer, L., Hauser, S.L. and Wands, J.R. (1992) Increased levels of neuronal thread protein in cerebrospinal fluid of patients with Alzheimer's disease. Ann. Neurol., 32: 733-742.
6. Gearing, M., Mori, H. and Mirra, S.S. (1996) Aβ-peptide length and apolipoprotein E genotype in Alzheimer's disease. Ann. Neurol., 39: 395-399.
7. Grubb, A., Jensson, O., Gudmundsson, G., Arnason, A., Lofberg, H. and Malm, J. (1984) Abnormal metabolism of γ-trace alkaline microproteins. The basic defect in hereditary cerebral hemorrhage with amyloidosis. N. Engl. J. Med., 311: 1547-1549.
8. Haass, C., Schlossmacher, M.G., Hung, A.Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B.L., Lieberburg, I., Koo, E.H., Schenk, D., Teplow, D.B. and Selkoe, D.J. (1992) Amyloid β-peptide is produced by cultured cells during normal metabolism. Nature, 359: 322-325.
9. Hock, C., Golombowski, S., Naser, W. and Muller-Spahn, F. (1995) Increased levels of τ protein in cerebrospinal fluid of patients with Alzheimer's disease-correlation with degree of cognitive impairment. Ann. Neurol., 37: 414-415.
10. Iwatsubo, T., Odaka, A., Suzuki, N., Mizusawa, H., Nukina, N. and Ihara, Y. (1994) Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: evidence that an initially deposited sepecies is Aβ42(43). Neuron, 13: 45-53.
11. Jarrett, J.T., Berger, E.P. and Lansbury, P.T. (1993) The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: implication for the pathogenesis of Alzheimer's disease. Biochemistry, 32: 4693-4697.
12. Kang, J., Lemaire, H.-G., Unterbeck, A., Salbaum, J.M., Masters, C.L., Grzeschik, K.-H., Multhaup, G., Beyreuther, K. and Muller-Hill, B. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature, 325: 733-736.
13. Kitaguchi, N., Tokushima, Y., Oishi, K., Takahashi, Y., Shiojiri, S., Nakamura, S., Tanaka, S., Kodaira, R. and Ito, H. (1990) Determination of amyloid β protein precursors harboring active form of proteinase inhibitor domains in cerebrospinal fluid of Alzheimer's disease patients by trypsin-antibody sandwich ELISA. Biochem. Biophys. Res. Commun., 166: 1453-1459.
14. Mann, D.M.A., Iwatsubo, T., Fukumoto, H., Ihara, Y., Odaka, A. and Suzuki, N. (1995) Microglial cells and amyloid β protein (Aβ) deposition: association with Aβ40-containing plaques. Acta Neuropathol., 90: 472-477.
15. Matsubara, E., Hirai, S., Amari, M., Shoji, M., Yamaguchi, H., Okamoto, K., Ishiguro, K., Harigaya Y. and Wakabayashi K. (1990) α1-Antichymotrypsin as a possible marker for Alzheimer-type dementia. Ann. Neurol., 28: 561-567.
16. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. and Stadlan, E.M. (1984) Clinical diagnosis of Alzheimer's disease; report of the NINCDS-ADEDA working group under the auspices of the Department of Health and Human Services task force on Alzheimer's disease. Neurology, 34: 939-944.
17. Miller, D.L., Papayannopouls, I.A., Styles, J., Bobin, S.A., Lin, Y.Y., Biemann, K. and Iqbal, K. (1993) Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease. Arch. Biochem. Biophys., 301: 41-52.
18. Mori, H., Hosoda, K., Matsubara, E., Nakamoto, T., Furiya, Y., Endoh, R., Usami, M., Shoji, M., Maruyama, S. and Hirai, S. (1995) Tau in cerebrospinal fluids: establishment of the sandwich ELISA with antibody specific to the repeat sequence in tau. Neurosci. Lett., 186: 181-183.
19. Motter, R., Vigo-Pelfrey, C., Kholodenko, D., Barbour, B., Johnson-Wood, K., Galasko, D., Chang, L., Miller, B., Clark, C., Green, R., Olson, D., Southwich, P., Wolfert, R., Munroe, B., Lieberburg, I., Seubert, P. and Schenk, D. (1995) Reduction of β-amyloid peptide 42 in the cerebrospinal fluid of patients with Alzheimer's disease. Ann. Neurol., 38: 643-648.
20. Mullan, M. and Crawfold, F. (1993) Genetic and molecular advances in Alzheimer's disease. Trends Neurosci., 10: 398-403.
21. Nakamura, T., Shoji, M., Harigaya, Y., Watanabe, M., Hosoda, K., Cheung, T.T., Shaffer, L.M., Golde, T.E., Younkin, L.H., Younkin, S.G. and Hirai, S. (1994) Amyloid b protein levels in cerebrospinal fluid are elevated in early-onset Alzheimer's disease. Ann. Neurol., 36: 903-911.
22. Nitsch, R.M., Rebeck, G.W., Deng, M., Richardson, I., Tennis, M., Shenk, D.B., Vigo-Pelfrey, C., Lieberburg, I., Wurtman, R.J., Hyman, B.T. and Growdon, J.H. (1995) Cerebrospinal fluid levels of amyloid b-protein in Alzheimer's disease; inverse correlation with severity of dementia and effect of apolipoprotein E genotype. Ann. Neurol., 37: 512-518.
23. Pirttilä, T., Kim, K.S., Mehta, P.D., Frey, H. and Wisniewski, H.M. (1994) Soluble amyloid β-protein in the cerebrospinal fluid from patients with Alzheimer's disease, vascular dementia and controls. J. Neurol. Sci., 127: 90-95.
24. Roher, A.E., Lowenson, J.D., Clarke, S., Wolkow, C., Wang, R., Cotter, R.J., Reardon, I.M., Zurcher-Neely, H.A., Heinrikson, R.L., Ball, M.J. and Greenberg, B.D. (1993) Structual alterations in the peptide backbone of β-amyloid core protein may account for its deposition and stability in Alzheimer's disease. J. Biol. Chem., 268: 3072-3083.
25. Seubert, P., Vigo-Pelfrey, C., Esch, F., Lee, M., Dovey, H., Davis, D., Sinha, S., Schlossmacher, M., Whaley, J., Swindlehurst, C., McCormack, R., Wolfert, R., Selkoe, D., Lieberburg, I. and Shenk, D. (1992) Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids. Nature, 359: 352-327.
26. Shoji, M., Golde, T.E., Ghiso, J., Cheung, T.T., Estus, S.S., Shaffer, L.M., Cai, X.-D., McKay, D.M., Tintner, R., Frangione, B. and Younkin, S.G. (1992) Production of the Alzheimer amyloid β protein by normal proteolytic processing. Science, 258: 126-129.
27. Suzuki, N., Cheung, T.T., Cai, X.-D., Odaka, A., Otvos, L. Jr., Eckman, C., Golde, R.E. and Younkin, S.G. (1994) An increased percentage of long amyloid β protein secreted by familial amyloid β protein precursor (βAPP717) mutants. Science, 264: 1336-1340.
28. Tabaton, M., Nunzi, M.G., Xue, R., Usiak, M., Autilio-Gambetti, L. and Gambetti, P. (1994) Soluble amyloid β-protein is a marker of Alzheimer amyloid in brain but not in cerebrospinal fluid. Biochem. Biophys. Res. Commun., 200: 1598-1603.
29. Tamaoka, A., Kondo, T., Odaka, A., Sahara, N., Sawamura, N., Ozawa, K., Suzuki, N., Shoji, S. and Mori, H. (1994a) Biochemical evidence for the long-tail form (Aβ 1-42/43) of amyloid β protein as a seed molecule cerebral deposits of Alzheimer's disease. Biochem. Biophys. Res. Commun., 205: 834-842.
30. Tamaoka, A., Odaka, A., Ishibashi, Y., Usami, M., Sahara, N., Suzuki, N., Nukina, N., Mizusawa, H., Shoji, S., Kanazawa, I. and Mori, H. (1994b) APP717 missense mutation affects the ratio of amyloid β protein species (Aβ 1-42/43 and Aβ1-40) in familial Alzheimer's disease brain. J. Biol. Chem., 269: 32721-32724.
31. Tamaoka, A., Sawamura, N., Odaka, A., Suzuki, N., Mizusawa, H., Shoji, S. and Mori, H. (1995) Amyloid β protein (Aβ1-42/43) in cerebellar diffuse plaques: enzyme-linked immunosorbent assay and immunocytochemical study. Brain Res., 679: 151-156.
32. Tamaoka, A., Fukushima, T., Sawamura, N., Ishikawa, K., Oguni, E., Komatsuzaki, Y. and Shoji, S. (1996) Amyloid β protein in plasma from patients with sporadic Alzheimer's disease. J. Neurol. Sci., 151: 65-68.
33. Vandermeeren, M., Mercken, M., Vanmechelen, E., Six, J., de Voorde, A.V., Martin, J.-J. and Cras, P. (1993) Detection of τ proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay. J. Neurochem., 61: 1828-1834.
34. Van Gool, W.A., Kuiper, M.A., Walstra, G.J.M., Wolters, E.C. and Bolhuis, P.A. (1995) Concentrations of amyloid b protein in cerebrospinal fluid of patients with Alzheimer's disease. Ann. Neurol., 37: 277-279.
35. Vigo-Pelfrey, C., Lee, D., Keim, P., Lieberburg, I. and Schenk, D. (1993) Characterization of β-amyloid peptide from human cerebrospinal fluid. J. Neurochem., 61: 1965-1968.
36. Vigo-Pelfrey, C., Seubert, P., Barbour, R., Blomquist, C., Lee, M., Lee, D., Coria, F., Chang, L., Miller, B., Lieberburg, I. and Schenk, D. (1995) Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease. Neurology, 45: 788-793.
37. Wang, G.P., Iqbal, K., Bucht, G., Winblad, B., Wisniewski, H.M. and Grundke-Iqbal, I. (1991) Alzheimer's disease: paired helical filament immunoreactivity in cerebrospinal fluid. Acta Neuropathol., 82: 6-12.