-
1
-
-
0027421043
-
Loss of a yeast telomere: Arrest, recovery, and chromosome loss
-
Sandell LL, Zakian VA. Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell 1993;75:729-39.
-
(1993)
Cell
, vol.75
, pp. 729-739
-
-
Sandell, L.L.1
Zakian, V.A.2
-
2
-
-
2542464036
-
Checkpoint adaptation: Molecular mechanisms uncovered
-
Lupardus PJ, Cimprich KA. Checkpoint adaptation: molecular mechanisms uncovered. Cell 2004;117:555-6.
-
(2004)
Cell
, vol.117
, pp. 555-556
-
-
Lupardus, P.J.1
Cimprich, K.A.2
-
3
-
-
2542459341
-
Adaptation of a DNA replication check-point response depends upon inactivation of claspin by the Polo-like kinase
-
Yoo HY, Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG. Adaptation of a DNA replication check-point response depends upon inactivation of claspin by the Polo-like kinase. Cell 2004;117:575-88.
-
(2004)
Cell
, vol.117
, pp. 575-588
-
-
Yoo, H.Y.1
Kumagai, A.2
Shevchenko, A.3
Shevchenko, A.4
Dunphy, W.G.5
-
7
-
-
0012966157
-
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc2SA
-
Soørensen CS, Syljuåsen RG, Falck J, et al. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc2SA. Cancer Cell 2003;3:247-58.
-
(2003)
Cancer Cell
, vol.3
, pp. 247-258
-
-
Soørensen, C.S.1
Syljuåsen, R.G.2
Falck, J.3
-
8
-
-
10844237358
-
Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing radiation
-
Syljuåsen RG, Soørensen CS, Nylandsted J, Lukas C, Lukas J, Bartek J. Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing radiation. Cancer Res 2004;64:9035-40.
-
(2004)
Cancer Res
, vol.64
, pp. 9035-9040
-
-
Syljuåsen, R.G.1
Soørensen, C.S.2
Nylandsted, J.3
Lukas, C.4
Lukas, J.5
Bartek, J.6
-
9
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998;273:5858-68.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
10
-
-
0037884963
-
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses
-
Rothkamm K, Lobrich M. Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses. Proc Natl Acad Sci U S A 2003;100:5057-62.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5057-5062
-
-
Rothkamm, K.1
Lobrich, M.2
-
11
-
-
3242879828
-
Chk1 in the DNA damage response: Conserved roles from yeasts to mammals
-
Chen Y, Sanchez Y. Chk1 in the DNA damage response: conserved roles from yeasts to mammals. DNA Repair (Amst) 2004;3:1025-32.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1025-1032
-
-
Chen, Y.1
Sanchez, Y.2
-
12
-
-
20544478438
-
DNA-dependent phosphorylation of Chk1 and claspin in a human cell-free system
-
Clarke CA, Clarke PR. DNA-dependent phosphorylation of Chk1 and claspin in a human cell-free system. Biochem J 2005;388:705-12.
-
(2005)
Biochem J
, vol.388
, pp. 705-712
-
-
Clarke, C.A.1
Clarke, P.R.2
-
13
-
-
20244388673
-
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
-
Syljuåsen RG, Soørensen CS, Hansen LT, et al. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. Mol Cell Biol 2005;25:3553-62.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3553-3562
-
-
Syljuåsen, R.G.1
Soørensen, C.S.2
Hansen, L.T.3
-
15
-
-
18844405191
-
PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints
-
Lu X, Nannenga B, Donehower LA. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints. Genes Dev 2005;19:1162-74.
-
(2005)
Genes Dev
, vol.19
, pp. 1162-1174
-
-
Lu, X.1
Nannenga, B.2
Donehower, L.A.3
-
16
-
-
33644683073
-
Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus egg extracts requires binding of ATRIP to ATR but not the stable DNA-binding or coued-coil domains of ATRIP
-
Kim SM, Kumagai A, Lee J, Dunphy WG. Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus egg extracts requires binding of ATRIP to ATR but not the stable DNA-binding or coued-coil domains of ATRIP. J Biol Chem 2005;280:38355-64.
-
(2005)
J Biol Chem
, vol.280
, pp. 38355-38364
-
-
Kim, S.M.1
Kumagai, A.2
Lee, J.3
Dunphy, W.G.4
-
17
-
-
33645316142
-
Targeting polo-like kinase 1 for cancer therapy
-
Strebhardt K, Ullrich A. Targeting polo-like kinase 1 for cancer therapy. Nat Rev Cancer 2006;6:321-30.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 321-330
-
-
Strebhardt, K.1
Ullrich, A.2
-
18
-
-
0032859695
-
CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers
-
Bertoni F, Codegoni AM, Furlan D, Tibiletti MG, Capella C, Broggini M. CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers. Genes Chromosomes Cancer 1999;26:176-80.
-
(1999)
Genes Chromosomes Cancer
, vol.26
, pp. 176-180
-
-
Bertoni, F.1
Codegoni, A.M.2
Furlan, D.3
Tibiletti, M.G.4
Capella, C.5
Broggini, M.6
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