메뉴 건너뛰기




Volumn 28, Issue 5-6, 2007, Pages 481-506

Modulation of signal transduction by vitamin E

Author keywords

Gene expression; Membrane translocation; Protein kinase; Protein phosphatase; Signal transduction; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL DERIVATIVE; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE; CELL SURFACE RECEPTOR; CYCLOOXYGENASE 2; CYTOKINE; DIACYLGLYCEROL KINASE; GROWTH FACTOR; LIPID; PHOSPHOLIPASE A2; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE;

EID: 35448939592     PISSN: 00982997     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mam.2006.12.009     Document Type: Review
Times cited : (149)

References (169)
  • 1
    • 0034565080 scopus 로고    scopus 로고
    • Synergistic inhibition of cyclooxygenase-2 expression by vitamin E and aspirin
    • Abate A., Yang G., Dennery P.A., Oberle S., and Schroder H. Synergistic inhibition of cyclooxygenase-2 expression by vitamin E and aspirin. Free Radic. Biol. Med. 29 11 (2000) 1135-1142
    • (2000) Free Radic. Biol. Med. , vol.29 , Issue.11 , pp. 1135-1142
    • Abate, A.1    Yang, G.2    Dennery, P.A.3    Oberle, S.4    Schroder, H.5
  • 2
    • 33846998312 scopus 로고    scopus 로고
    • gamma-tocotrienol inhibits nuclearfactor-kappaB signaling pathway through inhibition of RIP and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis
    • Ahn K.S., Sethi G., Krishnan K., and Aggarwal B.B. gamma-tocotrienol inhibits nuclearfactor-kappaB signaling pathway through inhibition of RIP and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. J. Biol. Chem. 282 1 (2006) 809-820
    • (2006) J. Biol. Chem. , vol.282 , Issue.1 , pp. 809-820
    • Ahn, K.S.1    Sethi, G.2    Krishnan, K.3    Aggarwal, B.B.4
  • 3
  • 4
    • 0026058246 scopus 로고
    • Inhibition of IL-1 beta expression in THP-1 cells by probucol and tocopherol
    • Akeson A.L., Woods C.W., Mosher L.B., Thomas C.E., and Jackson R.L. Inhibition of IL-1 beta expression in THP-1 cells by probucol and tocopherol. Atherosclerosis 86 2-3 (1991) 261-270
    • (1991) Atherosclerosis , vol.86 , Issue.2-3 , pp. 261-270
    • Akeson, A.L.1    Woods, C.W.2    Mosher, L.B.3    Thomas, C.E.4    Jackson, R.L.5
  • 5
    • 0029942186 scopus 로고    scopus 로고
    • Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
    • Andjelkovic M., Jakubowicz T., Cron P., Ming X.F., Han J.W., and Hemmings B.A. Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. Proc. Natl. Acad. Sci. U. S. A. 93 12 (1996) 5699-5704
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , Issue.12 , pp. 5699-5704
    • Andjelkovic, M.1    Jakubowicz, T.2    Cron, P.3    Ming, X.F.4    Han, J.W.5    Hemmings, B.A.6
  • 6
    • 0037201947 scopus 로고    scopus 로고
    • The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade
    • Andresen B.T., Rizzo M.A., Shome K., and Romero G. The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade. FEBS Lett. 531 l (2002) 65-68
    • (2002) FEBS Lett. , vol.531 , Issue.l , pp. 65-68
    • Andresen, B.T.1    Rizzo, M.A.2    Shome, K.3    Romero, G.4
  • 7
    • 0842321777 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B
    • Asehnoune K., Strassheim D., Mitra S., Kim J.Y., and Abraham E. Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B. J. Immunol. 172 4 (2004) 2522-2529
    • (2004) J. Immunol. , vol.172 , Issue.4 , pp. 2522-2529
    • Asehnoune, K.1    Strassheim, D.2    Mitra, S.3    Kim, J.Y.4    Abraham, E.5
  • 9
    • 0033521019 scopus 로고    scopus 로고
    • Roles of superoxide radical anion in signal transduction mediated by reversible regulation of protein-tyrosine phosphatase IB
    • Barrett W.C., DeGnore J.P., Keng Y.F., Zhang Z.Y., Yim M.B., and Chock P.B. Roles of superoxide radical anion in signal transduction mediated by reversible regulation of protein-tyrosine phosphatase IB. J. Biol. Chem. 274 49 (1999) 34543-34546
    • (1999) J. Biol. Chem. , vol.274 , Issue.49 , pp. 34543-34546
    • Barrett, W.C.1    DeGnore, J.P.2    Keng, Y.F.3    Zhang, Z.Y.4    Yim, M.B.5    Chock, P.B.6
  • 10
    • 16844380631 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signaling in the cellular response to oxidative stress
    • Barthel A., and Klotz L.O. Phosphoinositide 3-kinase signaling in the cellular response to oxidative stress. Biol. Chem. 386 3 (2005) 207-216
    • (2005) Biol. Chem. , vol.386 , Issue.3 , pp. 207-216
    • Barthel, A.1    Klotz, L.O.2
  • 11
    • 0033803072 scopus 로고    scopus 로고
    • Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation
    • Black T.M., Wang P., Maeda N., and Coleman R.A. Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. J. Nutr. 130 10 (2000) 2420-2426
    • (2000) J. Nutr. , vol.130 , Issue.10 , pp. 2420-2426
    • Black, T.M.1    Wang, P.2    Maeda, N.3    Coleman, R.A.4
  • 12
    • 0025806526 scopus 로고
    • Inhibition of cell proliferation by alpha-tocopherol. Role of protein kinase C
    • Boscoboinik D., Szewczyk A., Hensey C., and Azzi A. Inhibition of cell proliferation by alpha-tocopherol. Role of protein kinase C. J. Biol. Chem. 266 10 (1991) 6188-6194
    • (1991) J. Biol. Chem. , vol.266 , Issue.10 , pp. 6188-6194
    • Boscoboinik, D.1    Szewczyk, A.2    Hensey, C.3    Azzi, A.4
  • 13
    • 0037085442 scopus 로고    scopus 로고
    • Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells
    • Boudreau R.T., Garduno R., and Lin T.J. Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells. J. Biol. Chem. 277 7 (2002) 5322-5329
    • (2002) J. Biol. Chem. , vol.277 , Issue.7 , pp. 5322-5329
    • Boudreau, R.T.1    Garduno, R.2    Lin, T.J.3
  • 14
    • 0242322479 scopus 로고    scopus 로고
    • The effect of vitamin E on the structure of membrane lipid assemblies
    • Bradford A., Atkinson J., Fuller N., and Rand R.P. The effect of vitamin E on the structure of membrane lipid assemblies. J. Lipid. Res. 44 10 (2003) 1940-1945
    • (2003) J. Lipid. Res. , vol.44 , Issue.10 , pp. 1940-1945
    • Bradford, A.1    Atkinson, J.2    Fuller, N.3    Rand, R.P.4
  • 15
    • 0035876885 scopus 로고    scopus 로고
    • Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins
    • Breyer I., and Azzi A. Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins. Free Radic. Biol. Med. 30 12 (2001) 1381-1389
    • (2001) Free Radic. Biol. Med. , vol.30 , Issue.12 , pp. 1381-1389
    • Breyer, I.1    Azzi, A.2
  • 17
    • 28444432412 scopus 로고    scopus 로고
    • Is there a future for antioxidants in atherogenesis?
    • Brigelius-Flohe R., Kluth D., and Banning A. Is there a future for antioxidants in atherogenesis?. Mol. Nutr. Food Res. 49 11 (2005) 1083-1089
    • (2005) Mol. Nutr. Food Res. , vol.49 , Issue.11 , pp. 1083-1089
    • Brigelius-Flohe, R.1    Kluth, D.2    Banning, A.3
  • 18
    • 0033037413 scopus 로고    scopus 로고
    • Vitamin E: function and metabolism
    • Brigelius-Flohe R., and Traber M.G. Vitamin E: function and metabolism. FASEB. J. 13 10 (1999) 1145-1155
    • (1999) FASEB. J. , vol.13 , Issue.10 , pp. 1145-1155
    • Brigelius-Flohe, R.1    Traber, M.G.2
  • 19
    • 0032484209 scopus 로고    scopus 로고
    • alpha-tocopherol inhibits the respiratory burst in human monocytes. Attenuation of p47(phox) membrane translocation and phosphorylation
    • Cachia O., Benna J.E., Pedruzzi E., Descomps B., Gougerot-Pocidalo M.A., and Leger C.L. alpha-tocopherol inhibits the respiratory burst in human monocytes. Attenuation of p47(phox) membrane translocation and phosphorylation. J. Biol. Chem. 273 49 (1998) 32801-32805
    • (1998) J. Biol. Chem. , vol.273 , Issue.49 , pp. 32801-32805
    • Cachia, O.1    Benna, J.E.2    Pedruzzi, E.3    Descomps, B.4    Gougerot-Pocidalo, M.A.5    Leger, C.L.6
  • 20
    • 33644687454 scopus 로고    scopus 로고
    • PTEN activity is modulated during ischemia and reperfusion: involvement in the induction and decay of preconditioning
    • Cai Z., and Semenza G.L. PTEN activity is modulated during ischemia and reperfusion: involvement in the induction and decay of preconditioning. Circ. Res. 97 12 (2005) 1351-1359
    • (2005) Circ. Res. , vol.97 , Issue.12 , pp. 1351-1359
    • Cai, Z.1    Semenza, G.L.2
  • 21
    • 0035695424 scopus 로고    scopus 로고
    • Alpha-tocopherol modulates tyrosine phosphorylation in human neutrophils by inhibition of protein kinase C activity and activation of tyrosine phosphatases
    • Chan S.S., Monteiro H.P., Schindler F., Stern A., and Junqueira V.B. Alpha-tocopherol modulates tyrosine phosphorylation in human neutrophils by inhibition of protein kinase C activity and activation of tyrosine phosphatases. Free Radic. Res. 35 6 (2001) 843-856
    • (2001) Free Radic. Res. , vol.35 , Issue.6 , pp. 843-856
    • Chan, S.S.1    Monteiro, H.P.2    Schindler, F.3    Stern, A.4    Junqueira, V.B.5
  • 22
    • 0036296032 scopus 로고    scopus 로고
    • First structural evidence of a specific inhibition of phospholipase A2 by alpha-tocopherol (vitamin E) and its implications in inflammation: crystal structure of the complex formed between phospholipase A2 and alpha-tocopherol at 1.8 A resolution
    • Chandra V., Jasti J., Kaur P., Betzel C., Srinivasan A., and Singh T.P. First structural evidence of a specific inhibition of phospholipase A2 by alpha-tocopherol (vitamin E) and its implications in inflammation: crystal structure of the complex formed between phospholipase A2 and alpha-tocopherol at 1.8 A resolution. J. Mol. Biol. 320 2 (2002) 215-222
    • (2002) J. Mol. Biol. , vol.320 , Issue.2 , pp. 215-222
    • Chandra, V.1    Jasti, J.2    Kaur, P.3    Betzel, C.4    Srinivasan, A.5    Singh, T.P.6
  • 23
    • 20544475665 scopus 로고    scopus 로고
    • Membrane-protein interactions in cell signaling and membrane trafficking
    • Cho W., and Stahelin R.V. Membrane-protein interactions in cell signaling and membrane trafficking. Annu. Rev. Biophys. Biomol. Struct. 34 (2005) 119-151
    • (2005) Annu. Rev. Biophys. Biomol. Struct. , vol.34 , pp. 119-151
    • Cho, W.1    Stahelin, R.V.2
  • 25
    • 0037082354 scopus 로고    scopus 로고
    • Roles of protein kinase C and alpha-tocopherol in regulation of signal transduction for GATA-4 phosphorylation in HL-1 cardiac muscle cells
    • Clement S.A., Tan C.C., Guo J., Kitta K., and Suzuki Y.J. Roles of protein kinase C and alpha-tocopherol in regulation of signal transduction for GATA-4 phosphorylation in HL-1 cardiac muscle cells. Free Radic. Biol. Med. 32 4 (2002) 341-349
    • (2002) Free Radic. Biol. Med. , vol.32 , Issue.4 , pp. 341-349
    • Clement, S.A.1    Tan, C.C.2    Guo, J.3    Kitta, K.4    Suzuki, Y.J.5
  • 26
    • 26644439041 scopus 로고    scopus 로고
    • Modulation of the transforming growth factor betal by vitamin E in early nephropathy
    • Cojocel C., Al-Maghrebi M., Thomson M.S., Rawoot P., and Raghupathy R. Modulation of the transforming growth factor betal by vitamin E in early nephropathy. Med. Princ. Pract. 14 6 (2005) 422-429
    • (2005) Med. Princ. Pract. , vol.14 , Issue.6 , pp. 422-429
    • Cojocel, C.1    Al-Maghrebi, M.2    Thomson, M.S.3    Rawoot, P.4    Raghupathy, R.5
  • 28
    • 0001737772 scopus 로고    scopus 로고
    • Reversible regulation of SHP-1 tyrosine phosphatase activity by oxidation
    • Cunnick J.M., Dorsey J.F., Mei L., and Wu J. Reversible regulation of SHP-1 tyrosine phosphatase activity by oxidation. Biochem. Mol. Biol. Int. 45 5 (1998) 887-894
    • (1998) Biochem. Mol. Biol. Int. , vol.45 , Issue.5 , pp. 887-894
    • Cunnick, J.M.1    Dorsey, J.F.2    Mei, L.3    Wu, J.4
  • 29
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKTby the integrin-linked kinase
    • Delcommenne M., Tan C., Gray V., Rue L., Woodgett J., and Dedhar S. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKTby the integrin-linked kinase. Proc. Natl. Acad. Sci. U.S.A. 95 19 (1998) 1211-1216
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , Issue.19 , pp. 1211-1216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 30
    • 0032554611 scopus 로고    scopus 로고
    • Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation
    • Denu J.M., and Tanner K.G. Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation. Biochemistry 37 16 (1998) 5633-5642
    • (1998) Biochemistry , vol.37 , Issue.16 , pp. 5633-5642
    • Denu, J.M.1    Tanner, K.G.2
  • 31
    • 0031456719 scopus 로고    scopus 로고
    • Dose-response comparison of RRR-alpha-tocopherol and all-racemic alpha-tocopherol on LDL oxidation
    • Devaraj S., Adams-Huet B., Fuller C.J., and Jialal I. Dose-response comparison of RRR-alpha-tocopherol and all-racemic alpha-tocopherol on LDL oxidation. Arterioscler. Thromb. Vase. Biol. 17 10 (1997) 2273-2279
    • (1997) Arterioscler. Thromb. Vase. Biol. , vol.17 , Issue.10 , pp. 2273-2279
    • Devaraj, S.1    Adams-Huet, B.2    Fuller, C.J.3    Jialal, I.4
  • 32
    • 0032892223 scopus 로고    scopus 로고
    • Alpha-tocopherol decreases interleukin-1 beta release from activated human monocytes by inhibition of 5-lipoxygenase
    • Devaraj S., and Jialal I. Alpha-tocopherol decreases interleukin-1 beta release from activated human monocytes by inhibition of 5-lipoxygenase. Arterioscler. Thromb. Vase. Biol. 19 4 (1999) 1125-1133
    • (1999) Arterioscler. Thromb. Vase. Biol. , vol.19 , Issue.4 , pp. 1125-1133
    • Devaraj, S.1    Jialal, I.2
  • 33
    • 0029862109 scopus 로고    scopus 로고
    • The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium
    • Devaraj S., Li D., and Jialal I. The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium. J. Clin. Invest. 98 3 (1996) 756-763
    • (1996) J. Clin. Invest. , vol.98 , Issue.3 , pp. 756-763
    • Devaraj, S.1    Li, D.2    Jialal, I.3
  • 35
    • 0022456245 scopus 로고
    • Vitamin E inhibits platelet phospholipase A2
    • Douglas C.E., Chan A.C., and Choy P.C. Vitamin E inhibits platelet phospholipase A2. Biochim. Biophys. Acta 876 3 (1986) 639-645
    • (1986) Biochim. Biophys. Acta , vol.876 , Issue.3 , pp. 639-645
    • Douglas, C.E.1    Chan, A.C.2    Choy, P.C.3
  • 36
    • 0035667956 scopus 로고    scopus 로고
    • Modulation of microglial superoxide production by alpha-tocopherol in vitro: attenuation of p67phox translocation by a protein phosphatase-dependent pathway
    • Egger T., Hammer A., Wintersperger A., Goti D., Malle E., and Saltier W. Modulation of microglial superoxide production by alpha-tocopherol in vitro: attenuation of p67phox translocation by a protein phosphatase-dependent pathway. J. Neurochem. 79 6 (2001) 1169-1182
    • (2001) J. Neurochem. , vol.79 , Issue.6 , pp. 1169-1182
    • Egger, T.1    Hammer, A.2    Wintersperger, A.3    Goti, D.4    Malle, E.5    Saltier, W.6
  • 37
    • 0037338145 scopus 로고    scopus 로고
    • Vitamin E (alpha-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia
    • Egger T., Schuligoi R., Wintersperger A., Amann R., Malle E., and Sattler W. Vitamin E (alpha-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia. Biochem. J. 370 Pt 2 (2003) 459-467
    • (2003) Biochem. J. , vol.370 , Issue.PART 2 , pp. 459-467
    • Egger, T.1    Schuligoi, R.2    Wintersperger, A.3    Amann, R.4    Malle, E.5    Sattler, W.6
  • 38
    • 33748804968 scopus 로고    scopus 로고
    • Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders
    • Farooqui A.A., Ong W.Y., and Horrocks L.A. Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders. Pharmacol. Rev. 58 3 (2006) 591-620
    • (2006) Pharmacol. Rev. , vol.58 , Issue.3 , pp. 591-620
    • Farooqui, A.A.1    Ong, W.Y.2    Horrocks, L.A.3
  • 39
    • 4644359805 scopus 로고    scopus 로고
    • Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase
    • Feng J., Park J., Cron P., Hess D., and Hemmings B.A. Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase. J. Biol. Chem. 279 39 (2004) 41189-41196
    • (2004) J. Biol. Chem. , vol.279 , Issue.39 , pp. 41189-41196
    • Feng, J.1    Park, J.2    Cron, P.3    Hess, D.4    Hemmings, B.A.5
  • 40
    • 33745800033 scopus 로고    scopus 로고
    • alpha-tocopherol affects neuronal plasticity in adult rat dentate gyrus: The possible role of PKCdelta
    • Ferri P., Cecchini T., Ambrogini P., Betti M., Cuppini R., Grande P.D., and Ciaroni S. alpha-tocopherol affects neuronal plasticity in adult rat dentate gyrus: The possible role of PKCdelta. J. Neurobiol. 66 8 (2006) 793-810
    • (2006) J. Neurobiol. , vol.66 , Issue.8 , pp. 793-810
    • Ferri, P.1    Cecchini, T.2    Ambrogini, P.3    Betti, M.4    Cuppini, R.5    Grande, P.D.6    Ciaroni, S.7
  • 41
    • 0032843737 scopus 로고    scopus 로고
    • Structure-based functional motif identifies a potential disulfide oxidoreductase active site in the serine/threonine protein phosphatase-1 subfamily
    • Fetrow J.S., Slew N., and Skolnick J. Structure-based functional motif identifies a potential disulfide oxidoreductase active site in the serine/threonine protein phosphatase-1 subfamily. Faseb. J. 13 13 (1999) 1866-1874
    • (1999) Faseb. J. , vol.13 , Issue.13 , pp. 1866-1874
    • Fetrow, J.S.1    Slew, N.2    Skolnick, J.3
  • 42
    • 0034733807 scopus 로고    scopus 로고
    • Redox-dependent signal transduction
    • Finkel T. Redox-dependent signal transduction. FEES Lett. 476 1-2 (2000) 52-54
    • (2000) FEES Lett. , vol.476 , Issue.1-2 , pp. 52-54
    • Finkel, T.1
  • 43
    • 0037376674 scopus 로고    scopus 로고
    • Oxidant signals and oxidative stress
    • Finkel T. Oxidant signals and oxidative stress. Curr. Opin. Cell Biol. 15 2 (2003) 247-254
    • (2003) Curr. Opin. Cell Biol. , vol.15 , Issue.2 , pp. 247-254
    • Finkel, T.1
  • 44
    • 0034457888 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in the activation of tyrosine kinase and extracellular signal-regulated kinase by angiotensin II
    • Frank G.D., Eguchi S., Yamakawa T., Tanaka S., Inagami T., and Motley E.D. Involvement of reactive oxygen species in the activation of tyrosine kinase and extracellular signal-regulated kinase by angiotensin II. Endocrinology 141 9 (2000) 3120-3126
    • (2000) Endocrinology , vol.141 , Issue.9 , pp. 3120-3126
    • Frank, G.D.1    Eguchi, S.2    Yamakawa, T.3    Tanaka, S.4    Inagami, T.5    Motley, E.D.6
  • 45
    • 0029846809 scopus 로고    scopus 로고
    • Alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism
    • Freedman J.E., Farhat J.H., Loscalzo J., and Keaney Jr. J.F. Alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism. Circulation 94 10 (1996) 2434-2440
    • (1996) Circulation , vol.94 , Issue.10 , pp. 2434-2440
    • Freedman, J.E.1    Farhat, J.H.2    Loscalzo, J.3    Keaney Jr., J.F.4
  • 46
    • 15944396476 scopus 로고    scopus 로고
    • Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by d-alpha-tocopherol
    • Fukunaga-Takenaka R., Shirai Y., Yagi K., Adachi N., Sakai N., Merino E., Merida I., and Saito N. Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by d-alpha-tocopherol. Genes Cells 10 4 (2005) 311-319
    • (2005) Genes Cells , vol.10 , Issue.4 , pp. 311-319
    • Fukunaga-Takenaka, R.1    Shirai, Y.2    Yagi, K.3    Adachi, N.4    Sakai, N.5    Merino, E.6    Merida, I.7    Saito, N.8
  • 47
    • 1042267393 scopus 로고    scopus 로고
    • The effect of alpha- and gamma-tocopherol and their carboxyethyl hydroxychroman metabolites on prostate cancer cell proliferation
    • Galli F., Stabile A.M., Betti M., Conte C., Pistilli A., Rende M., Floridi A., and Azzi A. The effect of alpha- and gamma-tocopherol and their carboxyethyl hydroxychroman metabolites on prostate cancer cell proliferation. Arch. Biochem. Biophys. 423 1 (2004) 97-102
    • (2004) Arch. Biochem. Biophys. , vol.423 , Issue.1 , pp. 97-102
    • Galli, F.1    Stabile, A.M.2    Betti, M.3    Conte, C.4    Pistilli, A.5    Rende, M.6    Floridi, A.7    Azzi, A.8
  • 48
    • 3543117821 scopus 로고    scopus 로고
    • The development of phosphatidylinositol ether lipid analogues as inhibitors of the serine/threonine kinase, Akt
    • Gills J.J., and Dennis P.A. The development of phosphatidylinositol ether lipid analogues as inhibitors of the serine/threonine kinase, Akt. Expert Opin. Investig. Drugs 13 7 (2004) 787-797
    • (2004) Expert Opin. Investig. Drugs , vol.13 , Issue.7 , pp. 787-797
    • Gills, J.J.1    Dennis, P.A.2
  • 50
    • 0031912986 scopus 로고    scopus 로고
    • Dissimilar protection of tocopherol isomers against membrane hydrolysis by phospholipase A2
    • Grau A., and Ortiz A. Dissimilar protection of tocopherol isomers against membrane hydrolysis by phospholipase A2. Chem. Phys. Lipids 91 2 (1998) 109-118
    • (1998) Chem. Phys. Lipids , vol.91 , Issue.2 , pp. 109-118
    • Grau, A.1    Ortiz, A.2
  • 51
    • 0021279537 scopus 로고
    • New aspects of the inhibition of soybean lipoxygenase by alpha-tocopherol. Evidence for the existence of a specific complex
    • Grossman S., and Waksman E.G. New aspects of the inhibition of soybean lipoxygenase by alpha-tocopherol. Evidence for the existence of a specific complex. Int. J. Biochem. 16 3 (1984) 281-289
    • (1984) Int. J. Biochem. , vol.16 , Issue.3 , pp. 281-289
    • Grossman, S.1    Waksman, E.G.2
  • 53
    • 0030875938 scopus 로고    scopus 로고
    • High glucose-induced growth factor resistance in human fibroblasts can be reversed by antioxidants and protein kinase C-inhibitors
    • Hehenberger K., and Hansson A. High glucose-induced growth factor resistance in human fibroblasts can be reversed by antioxidants and protein kinase C-inhibitors. Cell Biochem. Funct. 15 3 (1997) 197-201
    • (1997) Cell Biochem. Funct. , vol.15 , Issue.3 , pp. 197-201
    • Hehenberger, K.1    Hansson, A.2
  • 55
    • 0033106369 scopus 로고    scopus 로고
    • Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels
    • Hicke L. Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels. Trends Cell Biol. 9 3 (1999) 107-112
    • (1999) Trends Cell Biol. , vol.9 , Issue.3 , pp. 107-112
    • Hicke, L.1
  • 56
    • 0035293622 scopus 로고    scopus 로고
    • Protein regulation by monoubiquitin
    • Hicke L. Protein regulation by monoubiquitin. Nat. Rev. Mol. Cell Biol. 2 3 (2001) 195-201
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , Issue.3 , pp. 195-201
    • Hicke, L.1
  • 57
    • 0035990924 scopus 로고    scopus 로고
    • Inhibition of protein kinase B/Akt implications for cancer therapy
    • Hill M.M., and Hemmings B.A. Inhibition of protein kinase B/Akt implications for cancer therapy. Pharmacol. Ther. 93 2-3 (2002) 243-251
    • (2002) Pharmacol. Ther. , vol.93 , Issue.2-3 , pp. 243-251
    • Hill, M.M.1    Hemmings, B.A.2
  • 59
    • 0033887478 scopus 로고    scopus 로고
    • Signaling and subcellular targeting by membrane-binding domains
    • Hurley J.H., and Misra S. Signaling and subcellular targeting by membrane-binding domains. Annu. Rev. Biophys. Biomol. Struct. 29 (2000) 49-79
    • (2000) Annu. Rev. Biophys. Biomol. Struct. , vol.29 , pp. 49-79
    • Hurley, J.H.1    Misra, S.2
  • 60
    • 0033886373 scopus 로고    scopus 로고
    • Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling
    • Irani K. Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. Circ. Res. 87 3 (2000) 179-183
    • (2000) Circ. Res. , vol.87 , Issue.3 , pp. 179-183
    • Irani, K.1
  • 61
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • Janssens V., and Goris J. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem. J. 353 Pt 3 (2001) 417-439
    • (2001) Biochem. J. , vol.353 , Issue.PART 3 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 62
    • 0038375011 scopus 로고    scopus 로고
    • gamma-Tocopherol, but not alpha-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats
    • Jiang Q., and Ames B.N. gamma-Tocopherol, but not alpha-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats. FASEB. J. 17 8 (2003) 816-822
    • (2003) FASEB. J. , vol.17 , Issue.8 , pp. 816-822
    • Jiang, Q.1    Ames, B.N.2
  • 63
    • 0035185941 scopus 로고    scopus 로고
    • gamma-Tocopherol, the major jorm of vitamin E in the US diet, deserves more attention
    • Jiang Q., Christen S., Shigenaga M.K., and Ames B.N. gamma-Tocopherol, the major jorm of vitamin E in the US diet, deserves more attention. Am. J. Clin. Nutr. 74 6 (2001) 714-722
    • (2001) Am. J. Clin. Nutr. , vol.74 , Issue.6 , pp. 714-722
    • Jiang, Q.1    Christen, S.2    Shigenaga, M.K.3    Ames, B.N.4
  • 64
    • 0034633629 scopus 로고    scopus 로고
    • gamma-Tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells
    • Jiang Q., Elson-Schwab I., Courtemanche C., and Ames B.N. gamma-Tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 97 21 (2000) 11494-11499
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , Issue.21 , pp. 11494-11499
    • Jiang, Q.1    Elson-Schwab, I.2    Courtemanche, C.3    Ames, B.N.4
  • 67
    • 10944274008 scopus 로고    scopus 로고
    • Inhibition of HMC-1 mast cell proliferation by vitamin E: involvement of the protein kinase B pathway
    • Kempna P., Reiter E., Arock M., Azzi A., and Zingg J.M. Inhibition of HMC-1 mast cell proliferation by vitamin E: involvement of the protein kinase B pathway. J. Biol. Chem. 279 49 (2004) 50700-50709
    • (2004) J. Biol. Chem. , vol.279 , Issue.49 , pp. 50700-50709
    • Kempna, P.1    Reiter, E.2    Arock, M.3    Azzi, A.4    Zingg, J.M.5
  • 68
    • 0037692884 scopus 로고    scopus 로고
    • Cloning of novel human SEC14p-like proteins: cellular localization, ligand binding and functional properties
    • Kempna P., Zingg J.M., Ricciarelli R., Hierl M., Saxena S., and Azzi A. Cloning of novel human SEC14p-like proteins: cellular localization, ligand binding and functional properties. Free Radic. Biol. Med. 34 (2003) 1458-1472
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 1458-1472
    • Kempna, P.1    Zingg, J.M.2    Ricciarelli, R.3    Hierl, M.4    Saxena, S.5    Azzi, A.6
  • 69
    • 0242290274 scopus 로고    scopus 로고
    • Molecular basis of vitamin E action. Tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-inducedneurodegeneration
    • Khanna S., Roy S., Ryu H., Bahadduri P., Swaan P.W., Ratan R.R., and Sen C.K. Molecular basis of vitamin E action. Tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-inducedneurodegeneration. J. Biol. Chem. 278 44 (2003) 43508-43515
    • (2003) J. Biol. Chem. , vol.278 , Issue.44 , pp. 43508-43515
    • Khanna, S.1    Roy, S.2    Ryu, H.3    Bahadduri, P.4    Swaan, P.W.5    Ratan, R.R.6    Sen, C.K.7
  • 70
    • 0034529484 scopus 로고    scopus 로고
    • Effects of administration of alpha-tocopherol and tocotrienols on serum lipids and liver HMG CoA reductase activity
    • Khor H.T., and Ng T.T. Effects of administration of alpha-tocopherol and tocotrienols on serum lipids and liver HMG CoA reductase activity. Int. J. Food Sci. Nutr. 51 Suppl. (2000) S3-S11
    • (2000) Int. J. Food Sci. Nutr. , vol.51 , Issue.SUPPL
    • Khor, H.T.1    Ng, T.T.2
  • 72
    • 0031093983 scopus 로고    scopus 로고
    • Prevention of glomerular dysfunction in diabetic rats by treatment with d-alpha-tocopherol
    • Koya D., Lee I.K., Ishii H., Kanoh H., and King G.L. Prevention of glomerular dysfunction in diabetic rats by treatment with d-alpha-tocopherol. J. Am. Soc. Nephrol. 8 3 (1997) 426-435
    • (1997) J. Am. Soc. Nephrol. , vol.8 , Issue.3 , pp. 426-435
    • Koya, D.1    Lee, I.K.2    Ishii, H.3    Kanoh, H.4    King, G.L.5
  • 73
    • 4043147112 scopus 로고    scopus 로고
    • Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases
    • Kyaw M., Yoshizumi M., Tsuchiya K., Izawa Y., Kanematsu Y., and Tamaki T. Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases. Acta Pharmacol. Sin. 25 8 (2004) 977-985
    • (2004) Acta Pharmacol. Sin. , vol.25 , Issue.8 , pp. 977-985
    • Kyaw, M.1    Yoshizumi, M.2    Tsuchiya, K.3    Izawa, Y.4    Kanematsu, Y.5    Tamaki, T.6
  • 74
    • 0034975973 scopus 로고    scopus 로고
    • Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells
    • Kyaw M., Yoshizumi M., Tsuchiya K., Kirima K., and Tamaki T. Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells. Hypertens. Res. 24 3 (2001) 251-261
    • (2001) Hypertens. Res. , vol.24 , Issue.3 , pp. 251-261
    • Kyaw, M.1    Yoshizumi, M.2    Tsuchiya, K.3    Kirima, K.4    Tamaki, T.5
  • 75
    • 0032546955 scopus 로고    scopus 로고
    • Reversible inactivation of protein-tyrosine phosphatase IB in A431 cells stimulated with epidermal growth factor
    • Lee S.R., Kwon K.S., Kim S.R., and Rhee S.G. Reversible inactivation of protein-tyrosine phosphatase IB in A431 cells stimulated with epidermal growth factor. J. Biol. Chem. 273 25 (1998) 15366-15372
    • (1998) J. Biol. Chem. , vol.273 , Issue.25 , pp. 15366-15372
    • Lee, S.R.1    Kwon, K.S.2    Kim, S.R.3    Rhee, S.G.4
  • 77
    • 0029915250 scopus 로고    scopus 로고
    • Tyrosine kinase activity modulates catalysis and translocation of cellular 5-lipoxygenase
    • Lepley R.A., Muskardin D.T., and Fitzpatrick F.A. Tyrosine kinase activity modulates catalysis and translocation of cellular 5-lipoxygenase. J. Biol. Chem. 271 11 (1996) 6179-6184
    • (1996) J. Biol. Chem. , vol.271 , Issue.11 , pp. 6179-6184
    • Lepley, R.A.1    Muskardin, D.T.2    Fitzpatrick, F.A.3
  • 78
    • 33750906556 scopus 로고    scopus 로고
    • The redox regulation of PI 3-kinase-dependent signaling
    • Leslie N.R. The redox regulation of PI 3-kinase-dependent signaling. Antioxid. Redox Signal 8 9-10 (2006) 1765-1774
    • (2006) Antioxid. Redox Signal , vol.8 , Issue.9-10 , pp. 1765-1774
    • Leslie, N.R.1
  • 79
    • 0142137134 scopus 로고    scopus 로고
    • Redox regulation of PI 3-kinase signalling via inactivation of PTEN
    • Leslie N.R., Bennett D., Lindsay Y.E., Stewart H., Gray A., and Downes C.P. Redox regulation of PI 3-kinase signalling via inactivation of PTEN. Embo. J. 22 20 (2003) 5501-5510
    • (2003) Embo. J. , vol.22 , Issue.20 , pp. 5501-5510
    • Leslie, N.R.1    Bennett, D.2    Lindsay, Y.E.3    Stewart, H.4    Gray, A.5    Downes, C.P.6
  • 80
    • 0036738755 scopus 로고    scopus 로고
    • Vitamin E inhibits IL-4 gene expression in peripheral blood T cells
    • Li-Weber M., Giaisi M., Treiber M.K., and Krammer P.H. Vitamin E inhibits IL-4 gene expression in peripheral blood T cells. Eur. J. Immunol. 32 9 (2002) 2401-2408
    • (2002) Eur. J. Immunol. , vol.32 , Issue.9 , pp. 2401-2408
    • Li-Weber, M.1    Giaisi, M.2    Treiber, M.K.3    Krammer, P.H.4
  • 82
    • 0034680307 scopus 로고    scopus 로고
    • Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-kappaB
    • Li D., Saldeen T., Romeo F., and Mehta J.L. Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-kappaB. Circulation 102 16 (2000) 1970-1976
    • (2000) Circulation , vol.102 , Issue.16 , pp. 1970-1976
    • Li, D.1    Saldeen, T.2    Romeo, F.3    Mehta, J.L.4
  • 83
    • 0037058642 scopus 로고    scopus 로고
    • Profiling of human cytokines in healthy individuals with vitamin E supplementation by antibody array
    • Lin Y., Huang R., Santanam N., Liu Y.G., Parthasarathy S., and Huang R.P. Profiling of human cytokines in healthy individuals with vitamin E supplementation by antibody array. Cancer Lett. 187 1-2 (2002) 17-24
    • (2002) Cancer Lett. , vol.187 , Issue.1-2 , pp. 17-24
    • Lin, Y.1    Huang, R.2    Santanam, N.3    Liu, Y.G.4    Parthasarathy, S.5    Huang, R.P.6
  • 84
    • 1842453964 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and inflammation in atherosclerosis
    • Linton M.F., and Fazio S. Cyclooxygenase-2 and inflammation in atherosclerosis. Curr. Opin. Pharmacol. 4 2 (2004) 116-123
    • (2004) Curr. Opin. Pharmacol. , vol.4 , Issue.2 , pp. 116-123
    • Linton, M.F.1    Fazio, S.2
  • 85
    • 0034008926 scopus 로고    scopus 로고
    • Transient translocation and activation of protein phosphatase 2A during mast cell secretion
    • Ludowyke R.I., Hoist J., Mudge L.M., and Sim A.T. Transient translocation and activation of protein phosphatase 2A during mast cell secretion. J. Biol. Chem. 275 9 (2000) 6144-6152
    • (2000) J. Biol. Chem. , vol.275 , Issue.9 , pp. 6144-6152
    • Ludowyke, R.I.1    Hoist, J.2    Mudge, L.M.3    Sim, A.T.4
  • 86
    • 0032296566 scopus 로고    scopus 로고
    • Inhibition of antigen and calcium ionophore induced secretion from RBL-2H3 cells by phosphatase inhibitors
    • Ludowyke R.I., Warton K., and Scurr L.L. Inhibition of antigen and calcium ionophore induced secretion from RBL-2H3 cells by phosphatase inhibitors. Cell Biol. Int. 22 11-12 (1998) 855-865
    • (1998) Cell Biol. Int. , vol.22 , Issue.11-12 , pp. 855-865
    • Ludowyke, R.I.1    Warton, K.2    Scurr, L.L.3
  • 87
    • 0023742699 scopus 로고
    • Vitamin E inhibits protein kinase C activity
    • Mahoney C.W., and Azzi A. Vitamin E inhibits protein kinase C activity. Biochem. Biophys. Res. Commun. 154 2 (1988) 694-697
    • (1988) Biochem. Biophys. Res. Commun. , vol.154 , Issue.2 , pp. 694-697
    • Mahoney, C.W.1    Azzi, A.2
  • 88
    • 1842591231 scopus 로고    scopus 로고
    • Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
    • Marmor M.D., and Yarden Y. Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases. Oncogene 23 11 (2004) 2057-2070
    • (2004) Oncogene , vol.23 , Issue.11 , pp. 2057-2070
    • Marmor, M.D.1    Yarden, Y.2
  • 89
    • 0032446835 scopus 로고    scopus 로고
    • Alpha-tocopherol but not beta-tocopherol inhibits thrombin-induced PKC activation and endothelin secretion in endothelial cells
    • Martin-Nizard F., Boullier A., Fruchart J.C., and Duriez P. Alpha-tocopherol but not beta-tocopherol inhibits thrombin-induced PKC activation and endothelin secretion in endothelial cells. Cardiovasc. Risk 5 5-6 (1998) 339-345
    • (1998) Cardiovasc. Risk , vol.5 , Issue.5-6 , pp. 339-345
    • Martin-Nizard, F.1    Boullier, A.2    Fruchart, J.C.3    Duriez, P.4
  • 90
    • 0029832485 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein induces activation of the transcription factor NF kappa B in fibroblasts, endothelial and smooth muscle cells
    • Maziere C., Auclair M., Djavaheri-Mergny M., Packer L., and Maziere J.C. Oxidized low density lipoprotein induces activation of the transcription factor NF kappa B in fibroblasts, endothelial and smooth muscle cells. Biochem. Mol. Biol. Int. 39 6 (1996) 1201-1207
    • (1996) Biochem. Mol. Biol. Int. , vol.39 , Issue.6 , pp. 1201-1207
    • Maziere, C.1    Auclair, M.2    Djavaheri-Mergny, M.3    Packer, L.4    Maziere, J.C.5
  • 91
    • 0035581273 scopus 로고    scopus 로고
    • Activation of JAK2 by the oxidative stress generated with oxidized low-density lipoprotein
    • Maziere C., Conte M.A., and Maziere J.C. Activation of JAK2 by the oxidative stress generated with oxidized low-density lipoprotein. Free Radic. Biol. Med. 31 11 (2001) 1334-1340
    • (2001) Free Radic. Biol. Med. , vol.31 , Issue.11 , pp. 1334-1340
    • Maziere, C.1    Conte, M.A.2    Maziere, J.C.3
  • 92
    • 28444477387 scopus 로고    scopus 로고
    • Plasma membrane phosphoinositide organization by protein electrostatics
    • McLaughlin S., and Murray D. Plasma membrane phosphoinositide organization by protein electrostatics. Nature 438 7068 (2005) 605-611
    • (2005) Nature , vol.438 , Issue.7068 , pp. 605-611
    • McLaughlin, S.1    Murray, D.2
  • 93
    • 4444233558 scopus 로고    scopus 로고
    • Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B
    • Meng T.C., Buckley D.A., Galic S., Tiganis T., and Tonks N.K. Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J. Biol. Chem. 279 36 (2004) 37716-37725
    • (2004) J. Biol. Chem. , vol.279 , Issue.36 , pp. 37716-37725
    • Meng, T.C.1    Buckley, D.A.2    Galic, S.3    Tiganis, T.4    Tonks, N.K.5
  • 94
    • 0036184190 scopus 로고    scopus 로고
    • Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
    • Meng T.C., Fukada T., and Tonks N.K. Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol. Cell 9 2 (2002) 387-399
    • (2002) Mol. Cell , vol.9 , Issue.2 , pp. 387-399
    • Meng, T.C.1    Fukada, T.2    Tonks, N.K.3
  • 95
    • 0035977098 scopus 로고    scopus 로고
    • Recognizing phosphatidylinositol 3-phosphate
    • Misra S., Miller G.J., and Hurley J.H. Recognizing phosphatidylinositol 3-phosphate. Cell 107 5 (2001) 559-562
    • (2001) Cell , vol.107 , Issue.5 , pp. 559-562
    • Misra, S.1    Miller, G.J.2    Hurley, J.H.3
  • 96
    • 0032906921 scopus 로고    scopus 로고
    • Apoptosis and cell-cycle arrest in human and murine tumor cells are initiated by isoprenoids
    • Mo H., and Elson C.E. Apoptosis and cell-cycle arrest in human and murine tumor cells are initiated by isoprenoids. J. Nutr. 129 4 (1999) 804-813
    • (1999) J. Nutr. , vol.129 , Issue.4 , pp. 804-813
    • Mo, H.1    Elson, C.E.2
  • 97
    • 3042736080 scopus 로고    scopus 로고
    • Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention
    • Mo H., and Elson C.E. Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention. Exp. Biol. Med. (Maywood) 229 7 (2004) 567-585
    • (2004) Exp. Biol. Med. (Maywood) , vol.229 , Issue.7 , pp. 567-585
    • Mo, H.1    Elson, C.E.2
  • 98
    • 15244357264 scopus 로고    scopus 로고
    • HIV protease inhibitors-induced atherosclerosis: prevention by alpha-tocopherol
    • Munteanu A., Ricciarelli R., and Zingg J.M. HIV protease inhibitors-induced atherosclerosis: prevention by alpha-tocopherol. IUBMB Life 56 10 (2004) 629-631
    • (2004) IUBMB Life , vol.56 , Issue.10 , pp. 629-631
    • Munteanu, A.1    Ricciarelli, R.2    Zingg, J.M.3
  • 99
    • 33646585823 scopus 로고    scopus 로고
    • Antagonistic effects of oxidized low density lipoprotein and {alpha}-tocopherol on CD36 scavenger receptor expression in monocytes: involvement of protein kinase B and peroxisome proliferator-activated receptor-{gamma}
    • Munteanu A., Taddei M., Tamburini I., Bergamini E., Azzi A., and Zingg J.M. Antagonistic effects of oxidized low density lipoprotein and {alpha}-tocopherol on CD36 scavenger receptor expression in monocytes: involvement of protein kinase B and peroxisome proliferator-activated receptor-{gamma}. J. Biol. Chem. 281 10 (2006) 6489-6497
    • (2006) J. Biol. Chem. , vol.281 , Issue.10 , pp. 6489-6497
    • Munteanu, A.1    Taddei, M.2    Tamburini, I.3    Bergamini, E.4    Azzi, A.5    Zingg, J.M.6
  • 100
    • 3142667617 scopus 로고    scopus 로고
    • Anti-atherosclerotic effects of vitamin E - myth or reality?
    • Munteanu A., Zingg J.M., and Azzi A. Anti-atherosclerotic effects of vitamin E - myth or reality?. J. Cell Mol. Med. 8 l (2004) 59-76
    • (2004) J. Cell Mol. Med. , vol.8 , Issue.l , pp. 59-76
    • Munteanu, A.1    Zingg, J.M.2    Azzi, A.3
  • 101
    • 15244358438 scopus 로고    scopus 로고
    • CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alpha-tocopherol
    • Munteanu A., Zingg J.M., Ricciarelli R., and Azzi A. CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alpha-tocopherol. Free Radic. Biol. Med. 38 8 (2005) 1047-1056
    • (2005) Free Radic. Biol. Med. , vol.38 , Issue.8 , pp. 1047-1056
    • Munteanu, A.1    Zingg, J.M.2    Ricciarelli, R.3    Azzi, A.4
  • 102
    • 0346749513 scopus 로고    scopus 로고
    • Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt
    • Murata H., Ihara Y., Nakamura H., Yodoi J., Sumikawa K., and Kondo T. Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt. J. Biol. Chem. 278 50 (2003) 50226-50233
    • (2003) J. Biol. Chem. , vol.278 , Issue.50 , pp. 50226-50233
    • Murata, H.1    Ihara, Y.2    Nakamura, H.3    Yodoi, J.4    Sumikawa, K.5    Kondo, T.6
  • 104
    • 4344559517 scopus 로고    scopus 로고
    • Erkl/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-l/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane
    • Myhre O., Sterri S.H., Bogen I.L., and Fonnum F. Erkl/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-l/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane. Toxicol. Sci. 80 2 (2004) 296-303
    • (2004) Toxicol. Sci. , vol.80 , Issue.2 , pp. 296-303
    • Myhre, O.1    Sterri, S.H.2    Bogen, I.L.3    Fonnum, F.4
  • 105
    • 0037155226 scopus 로고    scopus 로고
    • Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active site
    • Namgaladze D., Hofer H.W., and Ullrich V. Redox control of calcineurin by targeting the binuclear Fe(2+)-Zn(2+) center at the enzyme active site. J. Biol. Chem. 277 8 (2002) 5962-5969
    • (2002) J. Biol. Chem. , vol.277 , Issue.8 , pp. 5962-5969
    • Namgaladze, D.1    Hofer, H.W.2    Ullrich, V.3
  • 107
    • 27544490182 scopus 로고    scopus 로고
    • Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway
    • Ni J., Wen X., Yao J., Chang H.C., Yin Y., Zhang M., Xie S., Chen M., Simons B., Chang P., et al. Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway. Cancer Res. 65 21 (2005) 9807-9816
    • (2005) Cancer Res. , vol.65 , Issue.21 , pp. 9807-9816
    • Ni, J.1    Wen, X.2    Yao, J.3    Chang, H.C.4    Yin, Y.5    Zhang, M.6    Xie, S.7    Chen, M.8    Simons, B.9    Chang, P.10
  • 109
    • 33646077406 scopus 로고    scopus 로고
    • Vitamin E protected cultured cortical neurons from oxidative stress- induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
    • Numakawa Y., Nuniakawa T., Matsumoto T., Yagasaki Y., Kumamaru E., Kunugi H., Taguchi T., and Niki E. Vitamin E protected cultured cortical neurons from oxidative stress- induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. J. Neurochem. 97 4 (2006) 1191-1202
    • (2006) J. Neurochem. , vol.97 , Issue.4 , pp. 1191-1202
    • Numakawa, Y.1    Nuniakawa, T.2    Matsumoto, T.3    Yagasaki, Y.4    Kumamaru, E.5    Kunugi, H.6    Taguchi, T.7    Niki, E.8
  • 111
    • 0028959585 scopus 로고
    • New roles of low density lipoproteins and vitamin E in the pathogenesis of atherosclerosis
    • Ozer N.K., Boscoboinik D., and Azzi A. New roles of low density lipoproteins and vitamin E in the pathogenesis of atherosclerosis. Biochem. Mol. Biol. Int. 35 1 (1995) 117-124
    • (1995) Biochem. Mol. Biol. Int. , vol.35 , Issue.1 , pp. 117-124
    • Ozer, N.K.1    Boscoboinik, D.2    Azzi, A.3
  • 112
    • 0035146985 scopus 로고    scopus 로고
    • Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling
    • Packer L., Weber S.U., and Rimbach G. Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling. J. Nutr. 131 2 (2001) 369S-373S
    • (2001) J. Nutr. , vol.131 , Issue.2
    • Packer, L.1    Weber, S.U.2    Rimbach, G.3
  • 113
    • 0027288196 scopus 로고
    • Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    • Parker R.A., Pearce B.C., Clark R.W., Gordon D.A., and Wright J.J. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J. Biol. Chem. 268 15 (1993) 11230-11238
    • (1993) J. Biol. Chem. , vol.268 , Issue.15 , pp. 11230-11238
    • Parker, R.A.1    Pearce, B.C.2    Clark, R.W.3    Gordon, D.A.4    Wright, J.J.5
  • 114
    • 2442562698 scopus 로고    scopus 로고
    • Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase Calpha in endothelial cells
    • Partovian C., and Simons M. Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase Calpha in endothelial cells. Cell Signal 16 8 (2004) 951-957
    • (2004) Cell Signal , vol.16 , Issue.8 , pp. 951-957
    • Partovian, C.1    Simons, M.2
  • 115
    • 0026693801 scopus 로고
    • Hypocholesterolemic activity of synthetic and natural tocotrienols
    • Pearce B.C., Parker R.A., Deason M.E., Qureshi A.A., and Wright J.J. Hypocholesterolemic activity of synthetic and natural tocotrienols. J. Med. Chem. 35 20 (1992) 3595-3606
    • (1992) J. Med. Chem. , vol.35 , Issue.20 , pp. 3595-3606
    • Pearce, B.C.1    Parker, R.A.2    Deason, M.E.3    Qureshi, A.A.4    Wright, J.J.5
  • 116
    • 0026651784 scopus 로고
    • Tocopherol analogs suppress arachidonic acid metabolism via phospholipase inhibition
    • Pentland A.P., Morrison A.R., Jacobs S.C., Hruza L.L., Hebert J.S., and Packer L. Tocopherol analogs suppress arachidonic acid metabolism via phospholipase inhibition. J. Biol. Chem. 267 22 (1992) 15578-15584
    • (1992) J. Biol. Chem. , vol.267 , Issue.22 , pp. 15578-15584
    • Pentland, A.P.1    Morrison, A.R.2    Jacobs, S.C.3    Hruza, L.L.4    Hebert, J.S.5    Packer, L.6
  • 117
    • 0037452972 scopus 로고    scopus 로고
    • Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PISK and Akt
    • Qin S., and Chock P.B. Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PISK and Akt. Biochemistry 42 10 (2003) 2995-3003
    • (2003) Biochemistry , vol.42 , Issue.10 , pp. 2995-3003
    • Qin, S.1    Chock, P.B.2
  • 118
    • 0022343897 scopus 로고
    • Inhibition of 5-lipoxygenase by vitamin E
    • Reddanna P., Rao M.K., and Reddy C.C. Inhibition of 5-lipoxygenase by vitamin E. FEBS Lett. 193 1 (1985) 39-43
    • (1985) FEBS Lett. , vol.193 , Issue.1 , pp. 39-43
    • Reddanna, P.1    Rao, M.K.2    Reddy, C.C.3
  • 119
    • 0032528382 scopus 로고    scopus 로고
    • Regulation of recombinant PKC alpha activity by protein phosphatase 1 and protein phosphatase 2A
    • Ricciarelli R., and Azzi A. Regulation of recombinant PKC alpha activity by protein phosphatase 1 and protein phosphatase 2A. Arch. Biochem. Biophys. 355 2 (1998) 197-200
    • (1998) Arch. Biochem. Biophys. , vol.355 , Issue.2 , pp. 197-200
    • Ricciarelli, R.1    Azzi, A.2
  • 120
    • 0032528866 scopus 로고    scopus 로고
    • alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state
    • Ricciarelli R., Tasinato A., Clement S., Ozer N.K., Boscoboinik D., and Azzi A. alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state. Biochem. J. 334 Pt l (1998) 243-249
    • (1998) Biochem. J. , vol.334 , Issue.PART l , pp. 243-249
    • Ricciarelli, R.1    Tasinato, A.2    Clement, S.3    Ozer, N.K.4    Boscoboinik, D.5    Azzi, A.6
  • 121
    • 0035159165 scopus 로고    scopus 로고
    • Vitamin E: protective role of a Janus molecule
    • Ricciarelli R., Zingg J.M., and Azzi A. Vitamin E: protective role of a Janus molecule. FASEB. J. 15 13 (2001) 2314-2325
    • (2001) FASEB. J. , vol.15 , Issue.13 , pp. 2314-2325
    • Ricciarelli, R.1    Zingg, J.M.2    Azzi, A.3
  • 123
    • 0034604717 scopus 로고    scopus 로고
    • The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras
    • Rizzo M.A., Shome K., Watkins S.C., and Romero G. The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras. J. Biol. Chem. 275 31 (2000) 23911-23918
    • (2000) J. Biol. Chem. , vol.275 , Issue.31 , pp. 23911-23918
    • Rizzo, M.A.1    Shome, K.2    Watkins, S.C.3    Romero, G.4
  • 124
    • 0242611540 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and 5-lipoxygenase converging functions on cell proliferation and tumor angiogenesis: implications for cancer therapy
    • Romano M., and Claria J. Cyclooxygenase-2 and 5-lipoxygenase converging functions on cell proliferation and tumor angiogenesis: implications for cancer therapy. Faseb. J. 17 14 (2003) 1986-1995
    • (2003) Faseb. J. , vol.17 , Issue.14 , pp. 1986-1995
    • Romano, M.1    Claria, J.2
  • 125
    • 0038411479 scopus 로고    scopus 로고
    • Redox regulation of protein tyrosine phosphatase IB involves a sulphenyl-amide intermediate
    • Salmeen A., Andersen J.N., Myers M.P., Meng T.C., Hinks J.A., Tonks N.K., and Barford D. Redox regulation of protein tyrosine phosphatase IB involves a sulphenyl-amide intermediate. Nature 423 6941 (2003) 769-773
    • (2003) Nature , vol.423 , Issue.6941 , pp. 769-773
    • Salmeen, A.1    Andersen, J.N.2    Myers, M.P.3    Meng, T.C.4    Hinks, J.A.5    Tonks, N.K.6    Barford, D.7
  • 126
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov D.D., Guertin D.A., Ali S.M., and Sabatini D.M. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307 5712 (2005) 1098-1101
    • (2005) Science , vol.307 , Issue.5712 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 127
    • 0037862006 scopus 로고    scopus 로고
    • Unravelling the activation mechanisms of protein kinase B/Akt
    • Scheid M.P., and Woodgett J.R. Unravelling the activation mechanisms of protein kinase B/Akt. FEBS Lett. 546 1 (2003) 108-112
    • (2003) FEBS Lett. , vol.546 , Issue.1 , pp. 108-112
    • Scheid, M.P.1    Woodgett, J.R.2
  • 129
    • 33644891347 scopus 로고    scopus 로고
    • Tocotrienols: Vitamin E beyond tocopherols
    • Sen C.K., Khanna S., and Roy S. Tocotrienols: Vitamin E beyond tocopherols. Life Sci. 78 18 (2006) 2088-2098
    • (2006) Life Sci. , vol.78 , Issue.18 , pp. 2088-2098
    • Sen, C.K.1    Khanna, S.2    Roy, S.3
  • 130
    • 0034724679 scopus 로고    scopus 로고
    • Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells
    • Sen C.K., Khanna S., Roy S., and Packer L. Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells. J. Biol. Chem. 275 17 (2000) 13049-13055
    • (2000) J. Biol. Chem. , vol.275 , Issue.17 , pp. 13049-13055
    • Sen, C.K.1    Khanna, S.2    Roy, S.3    Packer, L.4
  • 131
    • 4444341393 scopus 로고    scopus 로고
    • Tocotrienol-induced caspase-8 activation is unrelated to death receptor apoptotic signaling in neoplastic mammary epithelial cells
    • Shah S., and Sylvester P.W. Tocotrienol-induced caspase-8 activation is unrelated to death receptor apoptotic signaling in neoplastic mammary epithelial cells. Exp. Biol. Med. (Maywood) 229 8 (2004) 745-755
    • (2004) Exp. Biol. Med. (Maywood) , vol.229 , Issue.8 , pp. 745-755
    • Shah, S.1    Sylvester, P.W.2
  • 132
    • 16444387293 scopus 로고    scopus 로고
    • Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity
    • Shah S.J., and Sylvester P.W. Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity. Exp. Biol. Med. (Maywood) 230 4 (2005) 235-241
    • (2005) Exp. Biol. Med. (Maywood) , vol.230 , Issue.4 , pp. 235-241
    • Shah, S.J.1    Sylvester, P.W.2
  • 133
    • 33744959427 scopus 로고    scopus 로고
    • alpha -Tocopheryl succinate induces apoptosis in prostate cancer cells in part through inhibition of BCL-XL/BCL-2 function
    • Shiau C.W., Huang J.W., Wang D.S., Weng J.R., Yang C.C., Lin C.H., Li C., and Chen C.S. alpha -Tocopheryl succinate induces apoptosis in prostate cancer cells in part through inhibition of BCL-XL/BCL-2 function. J. Biol. Chem. 281 17 (2006) 11819-11825
    • (2006) J. Biol. Chem. , vol.281 , Issue.17 , pp. 11819-11825
    • Shiau, C.W.1    Huang, J.W.2    Wang, D.S.3    Weng, J.R.4    Yang, C.C.5    Lin, C.H.6    Li, C.7    Chen, C.S.8
  • 134
    • 33749266374 scopus 로고    scopus 로고
    • Mast cell function: Regulation of degranulation by serine/threonine phosphatases
    • Sim A.T., Ludowyke R.I., and Verrills N.M. Mast cell function: Regulation of degranulation by serine/threonine phosphatases. Pharmacol. Ther. 112 2 (2006) 425-439
    • (2006) Pharmacol. Ther. , vol.112 , Issue.2 , pp. 425-439
    • Sim, A.T.1    Ludowyke, R.I.2    Verrills, N.M.3
  • 135
    • 0034896910 scopus 로고    scopus 로고
    • PX domains: attracted by phosphoinositides
    • Simonsen A., and Stenmark H. PX domains: attracted by phosphoinositides. Nat. Cell. Biol. 3 8 (2001) E179-E182
    • (2001) Nat. Cell. Biol. , vol.3 , Issue.8
    • Simonsen, A.1    Stenmark, H.2
  • 136
    • 23944493587 scopus 로고    scopus 로고
    • Vitamin E, oxidative stress, and inflammation
    • Singh U., Devaraj S., and Jialal I. Vitamin E, oxidative stress, and inflammation. Annu. Rev. Nutr. 25 (2005) 151-174
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 151-174
    • Singh, U.1    Devaraj, S.2    Jialal, I.3
  • 137
    • 0037102481 scopus 로고    scopus 로고
    • Differential susceptibilities of serine/threonine phosphatases to oxidative and nitrosative stress
    • Sommer D., Coleman S., Swanson S.A., and Stemmer P.M. Differential susceptibilities of serine/threonine phosphatases to oxidative and nitrosative stress. Arch. Biochem. Biophys. 404 2 (2002) 271-278
    • (2002) Arch. Biochem. Biophys. , vol.404 , Issue.2 , pp. 271-278
    • Sommer, D.1    Coleman, S.2    Swanson, S.A.3    Stemmer, P.M.4
  • 138
    • 33745139199 scopus 로고    scopus 로고
    • Tocopherol-mediated modulation of age-related changes in microglial cells: Turnover of extracellular oxidized protein material
    • Stolzing A., Widmer R., Jung T., Voss P., and Grune T. Tocopherol-mediated modulation of age-related changes in microglial cells: Turnover of extracellular oxidized protein material. Free Radic. Biol. Med. 40 12 (2006) 2126-2135
    • (2006) Free Radic. Biol. Med. , vol.40 , Issue.12 , pp. 2126-2135
    • Stolzing, A.1    Widmer, R.2    Jung, T.3    Voss, P.4    Grune, T.5
  • 139
    • 0033054154 scopus 로고    scopus 로고
    • The ubiquitin-proteasome system and endocytosis
    • Strous G.J., and Govers R. The ubiquitin-proteasome system and endocytosis. J. Cell Sci. 112 Pt 10 (1999) 1417-1423
    • (1999) J. Cell Sci. , vol.112 , Issue.PART 10 , pp. 1417-1423
    • Strous, G.J.1    Govers, R.2
  • 140
    • 0035675505 scopus 로고    scopus 로고
    • Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation
    • Sylvester P.W., Mclntyre B.S., Gapor A., and Brisk K.P. Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. Cell. Prolif. 34 6 (2001) 347-357
    • (2001) Cell. Prolif. , vol.34 , Issue.6 , pp. 347-357
    • Sylvester, P.W.1    Mclntyre, B.S.2    Gapor, A.3    Brisk, K.P.4
  • 141
    • 4444282844 scopus 로고    scopus 로고
    • Role of GTP-binding proteins in reversing the antiproliferative effects of tocotrienols in preneoplastic mammary epithelial cells
    • Sylvester P.W., Nachnani A., Shah S., and Briski K.P. Role of GTP-binding proteins in reversing the antiproliferative effects of tocotrienols in preneoplastic mammary epithelial cells. Asia Pac. J. Clin. Nutr. 11 Suppl 7 (2002) S452-S459
    • (2002) Asia Pac. J. Clin. Nutr. , vol.11 , Issue.SUPPL. 7
    • Sylvester, P.W.1    Nachnani, A.2    Shah, S.3    Briski, K.P.4
  • 142
    • 20144385472 scopus 로고    scopus 로고
    • Mechanisms mediating the antiproliferative and apoptotic effects of vitamin E in mammary cancer cells
    • Sylvester P.W., and Shah S.J. Mechanisms mediating the antiproliferative and apoptotic effects of vitamin E in mammary cancer cells. Front Biosci. 10 (2005) 699-709
    • (2005) Front Biosci. , vol.10 , pp. 699-709
    • Sylvester, P.W.1    Shah, S.J.2
  • 143
    • 20144363212 scopus 로고    scopus 로고
    • Intracellular signaling mechanisms mediating the antiproliferative and apoptotic effects of gamma-tocotrienol in neoplastic mammary epithelial cells
    • Sylvester P.W., Shah S.J., and Samant G.V. Intracellular signaling mechanisms mediating the antiproliferative and apoptotic effects of gamma-tocotrienol in neoplastic mammary epithelial cells. J. Plant Physiol. 162 7 (2005) 803-810
    • (2005) J. Plant Physiol. , vol.162 , Issue.7 , pp. 803-810
    • Sylvester, P.W.1    Shah, S.J.2    Samant, G.V.3
  • 144
    • 0030845007 scopus 로고    scopus 로고
    • Protective effect of d-alpha-tocopherol on the function of human mesangial cells exposed to high glucose concentrations
    • Tada H., Ishii H., and Isogai S. Protective effect of d-alpha-tocopherol on the function of human mesangial cells exposed to high glucose concentrations. Metabolism 46 7 (1997) 779-784
    • (1997) Metabolism , vol.46 , Issue.7 , pp. 779-784
    • Tada, H.1    Ishii, H.2    Isogai, S.3
  • 145
    • 20444426900 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells
    • Tan P.H., Sagoo P., Chan C., Yates J.B., Campbell J., Beutelspacher S.C., Foxwell B.M., Lombard G., and George A.J. Inhibition of NF-kappa B and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells. J. Immunol. 174 12 (2005) 7633-7644
    • (2005) J. Immunol. , vol.174 , Issue.12 , pp. 7633-7644
    • Tan, P.H.1    Sagoo, P.2    Chan, C.3    Yates, J.B.4    Campbell, J.5    Beutelspacher, S.C.6    Foxwell, B.M.7    Lombard, G.8    George, A.J.9
  • 146
    • 0029417282 scopus 로고
    • d-α-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties
    • Tasinato A., Boscoboinik D., Bartoli G.M., Maroni P., and Azzi A. d-α-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 12190-12194
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 12190-12194
    • Tasinato, A.1    Boscoboinik, D.2    Bartoli, G.M.3    Maroni, P.4    Azzi, A.5
  • 147
    • 0034644538 scopus 로고    scopus 로고
    • Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction
    • Teruel M.N., and Meyer T. Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction. Cell 103 2 (2000) 181-184
    • (2000) Cell , vol.103 , Issue.2 , pp. 181-184
    • Teruel, M.N.1    Meyer, T.2
  • 148
    • 0035513703 scopus 로고    scopus 로고
    • Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state
    • Teruel T., Hernandez R., and Lorenzo M. Ceramide mediates insulin resistance by tumor necrosis factor-alpha in brown adipocytes by maintaining Akt in an inactive dephosphorylated state. Diabetes 50 11 (2001) 2563-2571
    • (2001) Diabetes , vol.50 , Issue.11 , pp. 2563-2571
    • Teruel, T.1    Hernandez, R.2    Lorenzo, M.3
  • 149
    • 33144458615 scopus 로고    scopus 로고
    • Signaling roles of diacylglycerol kinases
    • Topham M.K. Signaling roles of diacylglycerol kinases. J. Cell Biochem. 97 3 (2006) 474-484
    • (2006) J. Cell Biochem. , vol.97 , Issue.3 , pp. 474-484
    • Topham, M.K.1
  • 150
    • 0025329796 scopus 로고
    • R,R,R-alpha-tocopherol potentiates prostacyclin release in human endothelial cells. Evidence for structural specificity of the tocopherol molecule
    • Tran K., and Chan A.C. R,R,R-alpha-tocopherol potentiates prostacyclin release in human endothelial cells. Evidence for structural specificity of the tocopherol molecule. Biochim. Biophys. Acta 1043 2 (1990) 189-197
    • (1990) Biochim. Biophys. Acta , vol.1043 , Issue.2 , pp. 189-197
    • Tran, K.1    Chan, A.C.2
  • 151
    • 0028275201 scopus 로고
    • Vitamin E suppresses diacylglycerol (DAG) level in thrombin-stimulated endothelial cells through an increase of DAG kinase activity
    • Tran K., Proulx P.R., and Chan A.C. Vitamin E suppresses diacylglycerol (DAG) level in thrombin-stimulated endothelial cells through an increase of DAG kinase activity. Biochim. Biophys. Acta 1212 2 (1994) 193-202
    • (1994) Biochim. Biophys. Acta , vol.1212 , Issue.2 , pp. 193-202
    • Tran, K.1    Proulx, P.R.2    Chan, A.C.3
  • 152
    • 27144462630 scopus 로고    scopus 로고
    • Ubiquitin and endocyticprotein sorting
    • Urbe S. Ubiquitin and endocyticprotein sorting. Essays Biochem. 41 (2005) 81-98
    • (2005) Essays Biochem. , vol.41 , pp. 81-98
    • Urbe, S.1
  • 153
    • 0035133884 scopus 로고    scopus 로고
    • Protein phosphatase 2A binds to the cytoplasmic tail of carboxypeptidase D and regulates post-trans-Golgi network trafficking
    • Varlamov O., Kalinina E., Che F.Y., and Fricker L.D. Protein phosphatase 2A binds to the cytoplasmic tail of carboxypeptidase D and regulates post-trans-Golgi network trafficking. J. Cell Sci. 114 Pt 2 (2001) 311-322
    • (2001) J. Cell Sci. , vol.114 , Issue.PART 2 , pp. 311-322
    • Varlamov, O.1    Kalinina, E.2    Che, F.Y.3    Fricker, L.D.4
  • 154
    • 0036342839 scopus 로고    scopus 로고
    • Effects of dietary omega3 and omega6 lipids and vitamin E on chemokine levels in autoimmune-prone MRL/MpJ-lpr/lpr mice
    • Venkatraman J., and Meksawan K. Effects of dietary omega3 and omega6 lipids and vitamin E on chemokine levels in autoimmune-prone MRL/MpJ-lpr/lpr mice. J. Nutr. Biochem. 13 8 (2002) 479
    • (2002) J. Nutr. Biochem. , vol.13 , Issue.8 , pp. 479
    • Venkatraman, J.1    Meksawan, K.2
  • 155
    • 3242722273 scopus 로고    scopus 로고
    • RRR-alpha-tocopherol decreases the expression of the major scavenger receptor, CD36, in human macrophages via inhibition oftyrosine kinase (Tyk2)
    • Venugopal S.K., Devaraj S., and Jialal I. RRR-alpha-tocopherol decreases the expression of the major scavenger receptor, CD36, in human macrophages via inhibition oftyrosine kinase (Tyk2). Atherosclerosis 175 2 (2004) 213-220
    • (2004) Atherosclerosis , vol.175 , Issue.2 , pp. 213-220
    • Venugopal, S.K.1    Devaraj, S.2    Jialal, I.3
  • 156
    • 0036787465 scopus 로고    scopus 로고
    • Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha
    • Venugopal S.K., Devaraj S., Yang T., and Jialal I. Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha. Diabetes 51 10 (2002) 3049-3054
    • (2002) Diabetes , vol.51 , Issue.10 , pp. 3049-3054
    • Venugopal, S.K.1    Devaraj, S.2    Yang, T.3    Jialal, I.4
  • 157
    • 32144458245 scopus 로고    scopus 로고
    • Vitamin E inhibits hemolysis induced by hemin as a membrane stabilizer
    • Wang F., Wang T., Lai J., Li M., and Zou C. Vitamin E inhibits hemolysis induced by hemin as a membrane stabilizer. Biochem. Pharmacol. 71 6 (2006) 799-805
    • (2006) Biochem. Pharmacol. , vol.71 , Issue.6 , pp. 799-805
    • Wang, F.1    Wang, T.2    Lai, J.3    Li, M.4    Zou, C.5
  • 158
    • 0032577226 scopus 로고    scopus 로고
    • Effects of tocotrienol on the intracellular translocation and degradation of apolipoprotein B: possible involvement of a proteasome independent pathway
    • Wang Q., Theriault A., Gapor A., and Adeli K. Effects of tocotrienol on the intracellular translocation and degradation of apolipoprotein B: possible involvement of a proteasome independent pathway. Biochem. Biophys. Res. Commun. 246 3 (1998) 640-643
    • (1998) Biochem. Biophys. Res. Commun. , vol.246 , Issue.3 , pp. 640-643
    • Wang, Q.1    Theriault, A.2    Gapor, A.3    Adeli, K.4
  • 159
    • 33746858490 scopus 로고    scopus 로고
    • Proteasome inhibition down-regulates endothelial nitric-oxide synthase phosphorylation and function
    • Wei Q., and Xia Y. Proteasome inhibition down-regulates endothelial nitric-oxide synthase phosphorylation and function. J. Biol. Chem. 281 31 (2006) 21652-21659
    • (2006) J. Biol. Chem. , vol.281 , Issue.31 , pp. 21652-21659
    • Wei, Q.1    Xia, Y.2
  • 161
    • 0031669304 scopus 로고    scopus 로고
    • Age- associated increase in PGE2 synthesis and COX activity in murine macrophages is reversed by vitamin E
    • Wu D., Mura C., Beharka A.A., Han S.N., Paulson K.E., Hwang D., and Meydani S.N. Age- associated increase in PGE2 synthesis and COX activity in murine macrophages is reversed by vitamin E. Am. J. Physiol. 275 3 Pt l (1998) C661-C668
    • (1998) Am. J. Physiol. , vol.275 , Issue.3 PART l
    • Wu, D.1    Mura, C.2    Beharka, A.A.3    Han, S.N.4    Paulson, K.E.5    Hwang, D.6    Meydani, S.N.7
  • 162
    • 0035152988 scopus 로고    scopus 로고
    • Vitamin E and macrophage cyclooxygenase regulation in the aged
    • Wu D.Y., Hayek M.G., and Meydani S.N. Vitamin E and macrophage cyclooxygenase regulation in the aged. J. Nutr. 131 2 (2001) 382S-388S
    • (2001) J. Nutr. , vol.131 , Issue.2
    • Wu, D.Y.1    Hayek, M.G.2    Meydani, S.N.3
  • 164
    • 0033746230 scopus 로고    scopus 로고
    • Vitamin E inhibits cell proliferation and the activation of extracellular signal-regulated kinase during the promotion phase of lung tumorigenesis irrespective ofantioxidative effect
    • Yano T., Yajima S., Hagiwara K., Kumadaki I., Yano Y., Otani S., Uchida M., and Ichikawa T. Vitamin E inhibits cell proliferation and the activation of extracellular signal-regulated kinase during the promotion phase of lung tumorigenesis irrespective ofantioxidative effect. Carcinogenesis 21 11 (2000) 2129-2133
    • (2000) Carcinogenesis , vol.21 , Issue.11 , pp. 2129-2133
    • Yano, T.1    Yajima, S.2    Hagiwara, K.3    Kumadaki, I.4    Yano, Y.5    Otani, S.6    Uchida, M.7    Ichikawa, T.8
  • 165
    • 0032571146 scopus 로고    scopus 로고
    • Alpha-tocopherol prevents ethanol-induced elevation of [Ca2+J]i in cultured canine cerebral vascular smooth musclecells
    • Zheng T., Li W., Zhang A., Altura B.T., and Altura B.M. Alpha-tocopherol prevents ethanol-induced elevation of [Ca2+J]i in cultured canine cerebral vascular smooth musclecells. Neurosci. Lett. 245 1 (1998) 17-20
    • (1998) Neurosci. Lett. , vol.245 , Issue.1 , pp. 17-20
    • Zheng, T.1    Li, W.2    Zhang, A.3    Altura, B.T.4    Altura, B.M.5
  • 166
    • 35448994058 scopus 로고    scopus 로고
    • Zingg, J.M., 2006. Modulation of signal transduction by vitamin E; Davos. MedimondInternational Proceedings, pp. 47-60.
  • 167
    • 2342502657 scopus 로고    scopus 로고
    • Non-antioxidant activities of vitamin E
    • Zingg J.M., and Azzi A. Non-antioxidant activities of vitamin E. Cur. Med. Chem. 11 9 (2004) 1113-1133
    • (2004) Cur. Med. Chem. , vol.11 , Issue.9 , pp. 1113-1133
    • Zingg, J.M.1    Azzi, A.2
  • 168
    • 34347385129 scopus 로고    scopus 로고
    • Modulation of Cellular Signalling and Gene Expression by Vitamin E
    • Bendrick O.H. (Ed), NOVA Publishers
    • Zingg J.M., and Azzi A. Modulation of Cellular Signalling and Gene Expression by Vitamin E. In: Bendrick O.H. (Ed). New Topics in Vitamin E Research (2006), NOVA Publishers
    • (2006) New Topics in Vitamin E Research
    • Zingg, J.M.1    Azzi, A.2
  • 169
    • 35448992614 scopus 로고    scopus 로고
    • Molecular Activities of Vitamin E
    • Meskin M.S., Bidlack W.R., and Randoph R.K. (Eds), Taylor & Francis
    • Zingg J.M., and Azzi A. Molecular Activities of Vitamin E. In: Meskin M.S., Bidlack W.R., and Randoph R.K. (Eds). Phytochemicals: Nutrient-Gene Interactions (2006), Taylor & Francis 175-206
    • (2006) Phytochemicals: Nutrient-Gene Interactions , pp. 175-206
    • Zingg, J.M.1    Azzi, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.