Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

Journal of Neurochemistry

Volumn 97, Issue 4, 2006, Pages 1191-1202

  Numakawa, Yumiko ^a   Numakawa, Tadahiro ^b   Matsumoto, Tomoya ^a   Yagasaki, Yuki ^b   Kumamaru, Emi ^b   Kunugi, Hiroshi ^b   Taguchi, Takahisa ^a   Niki, Etsuo ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

Bcl 2; Cell death; MAPK; PI3 kinase; Vitamin E

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA TOCOPHEROL; ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOTRIENOL; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN BCL 2; TROLOX C;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVATION; EXPOSURE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALPHA-TOCOPHEROL; ANIMALS; ANIMALS, NEWBORN; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CHROMANS; CYTOPROTECTION; ENZYME INHIBITORS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; UP-REGULATION; VITAMIN E;

ANIMALIA;

EID: 33646077406     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03827.x     Document Type: Article

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