-
1
-
-
0035936802
-
Atherosclerosis. The road ahead
-
Glass C.K. Witztum J.L. Atherosclerosis. the road ahead Cell 104 2001 503-516
-
(2001)
Cell
, vol.104
, pp. 503-516
-
-
Glass, C.K.1
Witztum, J.L.2
-
2
-
-
0025728865
-
Prostaglandin endoperoxide synthase: Structure and catalysis
-
Smith W.L. Marnett L.J. Prostaglandin endoperoxide synthase: structure and catalysis Biochim Biophys Acta 1083 1991 1-17
-
(1991)
Biochim. Biophys. Acta
, vol.1083
, pp. 1-17
-
-
Smith, W.L.1
Marnett, L.J.2
-
4
-
-
0023854087
-
Regulation of fibroblast cyclooxygenase synthesis by interleukin-1
-
Raz A. Wyche A. Siegel N. Needleman P. Regulation of fibroblast cyclooxygenase synthesis by interleukin-1 J Biol Chem 263 1988 3022-3028
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 3022-3028
-
-
Raz, A.1
Wyche, A.2
Siegel, N.3
Needleman, P.4
-
5
-
-
0030272216
-
In vivo and in vitro expression of a non-mammalian cyclooxygenase-1
-
Reed D.W. Bradshaw W.S. Xie W. Simmons D.L. In vivo and in vitro expression of a non-mammalian cyclooxygenase-1 Prostaglandins 52 1996 269-284
-
(1996)
Prostaglandins
, vol.52
, pp. 269-284
-
-
Reed, D.W.1
Bradshaw, W.S.2
Xie, W.3
Simmons, D.L.4
-
6
-
-
0032516490
-
Cyclooxygenase-2 induction in congestive heart failure friend or foe?
-
Wu K.K. Cyclooxygenase-2 induction in congestive heart failure friend or foe? Circulation 98 1998 95-96
-
(1998)
Circulation
, vol.98
, pp. 95-96
-
-
Wu, K.K.1
-
7
-
-
0037108979
-
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
-
Chandrasekharan N.V. Dai H. Roos K.L. Evanson N.K. Tomsik J. Elton T.S. Simmons D.L. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression Proc Natl Acad Sci U S A 99 2002 13926-13931
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13926-13931
-
-
Chandrasekharan, N.V.1
Dai, H.2
Roos, K.L.3
Evanson, N.K.4
Tomsik, J.5
Elton, T.S.6
Simmons, D.L.7
-
8
-
-
0028938598
-
Pharmacodynamic profile of prostacyclin
-
Vane J.R. Botting R.M. Pharmacodynamic profile of prostacyclin Am J Cardiol 75 1995 3A-10A
-
(1995)
Am. J. Cardiol.
, vol.75
-
-
Vane, J.R.1
Botting, R.M.2
-
10
-
-
0032948948
-
Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids
-
Catella-Lawson F. McAdam B. Morrison B.W. Kapoor S. Kujubu D. Antes L. Lasseter K.C. Quan H. Gertz B.J. FitzGerald G.A. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids J Pharmacol Exp Ther 289 1999 735-741
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 735-741
-
-
Catella-Lawson, F.1
McAdam, B.2
Morrison, B.W.3
Kapoor, S.4
Kujubu, D.5
Antes, L.6
Lasseter, K.C.7
Quan, H.8
Gertz, B.J.9
FitzGerald, G.A.10
-
11
-
-
0034900837
-
Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits
-
Wong E. Huang J. Tagari P. Riendeau D. Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits Atherosclerosis 157 2001 393-402
-
(2001)
Atherosclerosis
, vol.157
, pp. 393-402
-
-
Wong, E.1
Huang, J.2
Tagari, P.3
Riendeau, D.4
-
12
-
-
0034702914
-
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis
-
Belton O. Byrne D. Kearney D. Leahy A. Fitzgerald D.J. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis Circulation 102 2000 840-845
-
(2000)
Circulation
, vol.102
, pp. 840-845
-
-
Belton, O.1
Byrne, D.2
Kearney, D.3
Leahy, A.4
Fitzgerald, D.J.5
-
13
-
-
0037134011
-
Role of prostacyclin in the cardiovascular response to thromboxane A2
-
Cheng Y. Austin S.C. Rocca B. Koller B.H. Coffman T.M. Grosser T. Lawson J.A. FitzGerald G.A. Role of prostacyclin in the cardiovascular response to thromboxane A2 Science 296 2002 539-541
-
(2002)
Science
, vol.296
, pp. 539-541
-
-
Cheng, Y.1
Austin, S.C.2
Rocca, B.3
Koller, B.H.4
Coffman, T.M.5
Grosser, T.6
Lawson, J.A.7
FitzGerald, G.A.8
-
14
-
-
0030871687
-
COX-1 and COX-2 tissue expression: Implications and predictions
-
Crofford L.J. COX-1 and COX-2 tissue expression: implications and predictions J Rheumatol 24 1997 15-19
-
(1997)
J. Rheumatol.
, vol.24
, pp. 15-19
-
-
Crofford, L.J.1
-
16
-
-
0642373569
-
Reactive oxygen species mediate cyclooxygenase-2 induction during monocyte to macrophage differentiation: Critical role of NADPH oxidase
-
Barbieri S.S. Eligini S. Brambilla M. Tremoli E. Colli S. Reactive oxygen species mediate cyclooxygenase-2 induction during monocyte to macrophage differentiation: critical role of NADPH oxidase Cardiovasc Res 60 2003 187-197
-
(2003)
Cardiovasc. Res.
, vol.60
, pp. 187-197
-
-
Barbieri, S.S.1
Eligini, S.2
Brambilla, M.3
Tremoli, E.4
Colli, S.5
-
17
-
-
0029956219
-
Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: Possible role of cyclooxygenase-2
-
Hinson R.M. Williams J.A. Shacter E. Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: possible role of cyclooxygenase-2 Proc Natl Acad Sci U S A 93 1996 4885-4890
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4885-4890
-
-
Hinson, R.M.1
Williams, J.A.2
Shacter, E.3
-
18
-
-
0032491496
-
Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy
-
Cao H.J. Wang H.S. Zhang Y. Lin H.Y. Phipps R.P. Smith T.J. Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy J Biol Chem 273 1998 29615-29625
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29615-29625
-
-
Cao, H.J.1
Wang, H.S.2
Zhang, Y.3
Lin, H.Y.4
Phipps, R.P.5
Smith, T.J.6
-
19
-
-
0035082529
-
Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes
-
Callejas N.A. Casado M. Diaz-Guerra M.J. Bosca L. Martin-Sanz P. Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes Hepatology 33 2001 860-867
-
(2001)
Hepatology
, vol.33
, pp. 860-867
-
-
Callejas, N.A.1
Casado, M.2
Diaz-Guerra, M.J.3
Bosca, L.4
Martin-Sanz, P.5
-
20
-
-
0035374512
-
Monocyte membrane type 1-matrix metalloproteinase, Prostaglandin-dependent regulation and role in metalloproteinase-2 activation
-
Shankavaram U.T. Lai W.C. Netzel-Arnett S. Mangan P.R. Ardans J.A. Caterina N. Stetler-Stevenson W.G. Birkedal-Hansen H. Wahl L.M. Monocyte membrane type 1-matrix metalloproteinase, Prostaglandin-dependent regulation and role in metalloproteinase-2 activation J Biol Chem 276 2001 19027-19032
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19027-19032
-
-
Shankavaram, U.T.1
Lai, W.C.2
Netzel-Arnett, S.3
Mangan, P.R.4
Ardans, J.A.5
Caterina, N.6
Stetler-Stevenson, W.G.7
Birkedal-Hansen, H.8
Wahl, L.M.9
-
21
-
-
0031894321
-
Extracellular matrix modulates macrophage functions characteristic to atheroma: Collagen type I enhances acquisition of resident macrophage traits by human peripheral blood monocytes in vitro
-
Wesley II R.B. Meng X. Godin D. Galis Z.S. Extracellular matrix modulates macrophage functions characteristic to atheroma: collagen type I enhances acquisition of resident macrophage traits by human peripheral blood monocytes in vitro Arterioscler Thromb Vasc Biol 18 1998 432-440
-
(1998)
Arterioscler. Thromb. Vasc. Biol.
, vol.18
, pp. 432-440
-
-
Wesley II, R.B.1
Meng, X.2
Godin, D.3
Galis, Z.S.4
-
24
-
-
0028913698
-
Signal transduction in atherosclerosis: Second messengers and regulation of cellular cholesterol trafficking
-
Pomerantz K.B. Nicholson A.C. Hajjar D.P. Signal transduction in atherosclerosis: second messengers and regulation of cellular cholesterol trafficking Adv Exp Med Biol 369 1995 49-64
-
(1995)
Adv. Exp. Med. Biol.
, vol.369
, pp. 49-64
-
-
Pomerantz, K.B.1
Nicholson, A.C.2
Hajjar, D.P.3
-
25
-
-
0033015661
-
Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages
-
Baker C.S. Hall R.J. Evans T.J. Pomerance A. Maclouf J. Creminon C. Yacoub M.H. Polak J.M. Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages Arterioscler Thromb Vasc Biol 19 1999 646-655
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 646-655
-
-
Baker, C.S.1
Hall, R.J.2
Evans, T.J.3
Pomerance, A.4
Maclouf, J.5
Creminon, C.6
Yacoub, M.H.7
Polak, J.M.8
-
26
-
-
0027290813
-
Expression of a mitogen inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
-
Yamagata K. Andreasson K.I. Kaufmann W.E. Barnes C.A. Worley P.F. Expression of a mitogen inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids Neuron 11 1993 371-386
-
(1993)
Neuron
, vol.11
, pp. 371-386
-
-
Yamagata, K.1
Andreasson, K.I.2
Kaufmann, W.E.3
Barnes, C.A.4
Worley, P.F.5
-
27
-
-
0032839061
-
Cyclooxygenase knockout mice: Models for elucidating isoform-specific functions
-
Langenbach R. Loftin C. Lee C. Tiano H. Cyclooxygenase knockout mice: models for elucidating isoform-specific functions Biochem Pharmacol 58 1999 1237-1246
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 1237-1246
-
-
Langenbach, R.1
Loftin, C.2
Lee, C.3
Tiano, H.4
-
28
-
-
0037163149
-
Innate and adaptive immunity in the pathogenesis of atherosclerosis
-
Hansson G.K. Libby P. Schonbeck U. Yan Z.Q. Innate and adaptive immunity in the pathogenesis of atherosclerosis Circ Res 91 2002 281-291
-
(2002)
Circ. Res.
, vol.91
, pp. 281-291
-
-
Hansson, G.K.1
Libby, P.2
Schonbeck, U.3
Yan, Z.Q.4
-
29
-
-
0031715332
-
Oxidized low-density lipoprotein decreases the induced nitric oxide synthesis in rat mesangial cells
-
Wu Z.L. Liang M.Y. Qiu L.Q. Oxidized low-density lipoprotein decreases the induced nitric oxide synthesis in rat mesangial cells Cell Biochem Funct 16 1998 153-158
-
(1998)
Cell Biochem. Funct.
, vol.16
, pp. 153-158
-
-
Wu, Z.L.1
Liang, M.Y.2
Qiu, L.Q.3
-
30
-
-
0033000419
-
Oxidized low density lipoprotein suppresses expression of inducible cyclooxygenase in human macrophages
-
Eligini S. Colli S. Basso F. Sironi L. Tremoli E. Oxidized low density lipoprotein suppresses expression of inducible cyclooxygenase in human macrophages Arterioscler Thromb Vasc Biol 19 1999 1719-1725
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 1719-1725
-
-
Eligini, S.1
Colli, S.2
Basso, F.3
Sironi, L.4
Tremoli, E.5
-
31
-
-
0036070318
-
Oxidized phospholipids inhibit cyclooxygenase-2 in human macrophages via nuclear factor-kappaB/IkappaB- and ERK2-dependent mechanisms
-
Eligini S. Brambilla M. Banfi C. Camera M. Sironi L. Barbieri S.S. Auwerx J. Tremoli E. Colli S. Oxidized phospholipids inhibit cyclooxygenase-2 in human macrophages via nuclear factor-kappaB/IkappaB- and ERK2-dependent mechanisms Cardiovasc Res 55 2002 406-415
-
(2002)
Cardiovasc. Res.
, vol.55
, pp. 406-415
-
-
Eligini, S.1
Brambilla, M.2
Banfi, C.3
Camera, M.4
Sironi, L.5
Barbieri, S.S.6
Auwerx, J.7
Tremoli, E.8
Colli, S.9
-
33
-
-
0033553429
-
Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells
-
Dichtl W. Nilsson L. Goncalves I. Ares M.P. Banfi C. Calara F. Hamsten A. Eriksson P. Nilsson J. Very low-density lipoprotein activates nuclear factor-kappaB in endothelial cells Circ Res 84 1999 1085-1094
-
(1999)
Circ. Res.
, vol.84
, pp. 1085-1094
-
-
Dichtl, W.1
Nilsson, L.2
Goncalves, I.3
Ares, M.P.4
Banfi, C.5
Calara, F.6
Hamsten, A.7
Eriksson, P.8
Nilsson, J.9
-
34
-
-
0032843860
-
The nuclear transcription factor NF-kappaB mediates interleukin-1beta-induced expression of cyclooxygenase-2 in human myometrial cells
-
Belt A.R. Baldassare J.J. Molnar M. Romero R. Hertelendy F. The nuclear transcription factor NF-kappaB mediates interleukin-1beta-induced expression of cyclooxygenase-2 in human myometrial cells Am J Obstet Gynecol 181 1999 359-366
-
(1999)
Am. J. Obstet. Gynecol.
, vol.181
, pp. 359-366
-
-
Belt, A.R.1
Baldassare, J.J.2
Molnar, M.3
Romero, R.4
Hertelendy, F.5
-
35
-
-
0025187588
-
Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice
-
Masferrer J.L. Zweifel B.S. Seibert K. Needleman P. Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice J Clin Invest 86 1990 1375-1379
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 1375-1379
-
-
Masferrer, J.L.1
Zweifel, B.S.2
Seibert, K.3
Needleman, P.4
-
36
-
-
0346727295
-
Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice
-
Kanters E. Pasparakis M. Gijbels M.J. Vergouwe M.N. Partouns-Hendriks I. Fijneman R.J. Clausen B.E. Forster I. Kockx M.M. Rajewsky K. et al. Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice J Clin Invest 112 2003 1176-1185
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1176-1185
-
-
Kanters, E.1
Pasparakis, M.2
Gijbels, M.J.3
Vergouwe, M.N.4
Partouns-Hendriks, I.5
Fijneman, R.J.6
Clausen, B.E.7
Forster, I.8
Kockx, M.M.9
Rajewsky, K.10
-
37
-
-
0023805341
-
Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2
-
Second International Study of Infarct Survival Collaborative Group
-
Second International Study of Infarct Survival Collaborative Group: Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988, 2:349-360.
-
(1988)
Lancet
, vol.2
, pp. 349-360
-
-
-
38
-
-
0034074730
-
Indications for early aspirin use in acute ischemic stroke: A combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups
-
Chen Z.M. Sandercock P. Pan H.C. Counsell C. Collins R. Liu L.S. Xie J.X. Warlow C. Peto R. Indications for early aspirin use in acute ischemic stroke: a combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups Stroke 31 2000 1240-1249
-
(2000)
Stroke
, vol.31
, pp. 1240-1249
-
-
Chen, Z.M.1
Sandercock, P.2
Pan, H.C.3
Counsell, C.4
Collins, R.5
Liu, L.S.6
Xie, J.X.7
Warlow, C.8
Peto, R.9
-
39
-
-
0027942293
-
Antiplatelet therapy for thromboprophylaxis: The need for careful consideration of the evidence from randomised trials
-
Antiplatelet Trialists' Collaboration
-
Collins R. Baigent C. Sandercock P. Peto R. Antiplatelet therapy for thromboprophylaxis: the need for careful consideration of the evidence from randomised trials. Antiplatelet Trialists' Collaboration BMJ 309 1994 1215-1217
-
(1994)
BMJ
, vol.309
, pp. 1215-1217
-
-
Collins, R.1
Baigent, C.2
Sandercock, P.3
Peto, R.4
-
40
-
-
0030956673
-
Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
-
Ridker P.M. Cushman M. Stampfer M.J. Tracy R.T. Hennekens C.H. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men N Engl J Med 336 1997 973-979
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 973-979
-
-
Ridker, P.M.1
Cushman, M.2
Stampfer, M.J.3
Tracy, R.T.4
Hennekens, C.H.5
-
41
-
-
0015877843
-
Anti-inflammatory drugs in experimental atherosclerosis. I. Relative potencies for inhibiting plaque formation
-
Bailey J.M. Butler J. Anti-inflammatory drugs in experimental atherosclerosis. I. Relative potencies for inhibiting plaque formation Atherosclerosis 17 1973 515-522
-
(1973)
Atherosclerosis
, vol.17
, pp. 515-522
-
-
Bailey, J.M.1
Butler, J.2
-
42
-
-
0035853050
-
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice
-
Pratico D. Tillmann C. Zhang Z.B. Li H. FitzGerald G.A. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice Proc Natl Acad Sci U S A 98 2001 3358-3363
-
(2001)
Proc. Natl. Acad. Sci. U S A
, vol.98
, pp. 3358-3363
-
-
Pratico, D.1
Tillmann, C.2
Zhang, Z.B.3
Li, H.4
FitzGerald, G.A.5
-
43
-
-
0037117652
-
Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice
-
Burleigh M.E. Babaev V.R. Oates J.A. Harris R.C. Gautam S. Riendeau D. Marnett L.J. Morrow J.D. Fazio S. Linton M.F. Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice Circulation 105 2002 1816-1823
-
(2002)
Circulation
, vol.105
, pp. 1816-1823
-
-
Burleigh, M.E.1
Babaev, V.R.2
Oates, J.A.3
Harris, R.C.4
Gautam, S.5
Riendeau, D.6
Marnett, L.J.7
Morrow, J.D.8
Fazio, S.9
Linton, M.F.10
-
45
-
-
0024437922
-
Decreased prostaglandin production by cholesterol-rich macrophages
-
Mathur S.N. Albright E. Field F.J. Decreased prostaglandin production by cholesterol-rich macrophages J Lipid Res 30 1989 1385-1395
-
(1989)
J. Lipid Res.
, vol.30
, pp. 1385-1395
-
-
Mathur, S.N.1
Albright, E.2
Field, F.J.3
-
47
-
-
0035943611
-
Prostaglandin E2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1beta -treated human synovial fibroblasts
-
Faour W.H. He Y. He Q.W. de Ladurantaye M. Quintero M. Mancini A. Di Battista J.A. Prostaglandin E2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1beta -treated human synovial fibroblasts J Biol Chem 276 2001 31720-31731
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31720-31731
-
-
Faour, W.H.1
He, Y.2
He, Q.W.3
de Ladurantaye, M.4
Quintero, M.5
Mancini, A.6
Di Battista, J.A.7
-
48
-
-
0034736007
-
Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs
-
Hinz B. Brune K. Pahl A. Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs Biochem Biophys Res Commun 278 2000 790-796
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 790-796
-
-
Hinz, B.1
Brune, K.2
Pahl, A.3
-
49
-
-
0031870652
-
Macrophages in human atheroma contain PPARgamma: Differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro
-
Marx N. Sukhova G. Murphy C. Libby P. Plutzky J. Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro Am J Pathol 153 1998 17-23
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 17-23
-
-
Marx, N.1
Sukhova, G.2
Murphy, C.3
Libby, P.4
Plutzky, J.5
-
50
-
-
0032560545
-
Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
-
Ricote M. Huang J. Fajas L. Li A. Welch J. Najib J. Witztum J.L. Auwerx J. Palinski W. Glass C.K. Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein Proc Natl Acad Sci U S A 95 1998 7614-7619
-
(1998)
Proc. Natl. Acad. Sci. U S A
, vol.95
, pp. 7614-7619
-
-
Ricote, M.1
Huang, J.2
Fajas, L.3
Li, A.4
Welch, J.5
Najib, J.6
Witztum, J.L.7
Auwerx, J.8
Palinski, W.9
Glass, C.K.10
-
51
-
-
0032540012
-
PPAR-gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz P. Nagy L. Alvarez J.G.A. Thomazy V.A. Evans R.M. PPAR-gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL Cell 93 1998 241-252
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.A.3
Thomazy, V.A.4
Evans, R.M.5
-
52
-
-
0034623232
-
Feedback control of cyclooxygenase-2 expression through PPARgamma
-
Inoue H. Tanabe T. Umesono K. Feedback control of cyclooxygenase-2 expression through PPARgamma J Biol Chem 275 2000 28028-28032
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28028-28032
-
-
Inoue, H.1
Tanabe, T.2
Umesono, K.3
-
54
-
-
0036164154
-
BAREing it all: The adoption of LXR and FXR and their roles in lipid homeostasis
-
Edwards P.A. Kast H.R. Anisfeld A.M. BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis J Lipid Res 43 2002 2-12
-
(2002)
J. Lipid Res.
, vol.43
, pp. 2-12
-
-
Edwards, P.A.1
Kast, H.R.2
Anisfeld, A.M.3
-
55
-
-
0037385266
-
LXRs: New therapeutic targets in atherosclerosis?
-
Joseph S.B. Tontonoz P. LXRs: new therapeutic targets in atherosclerosis? Curr Opin Pharmacol 3 2003 192-197
-
(2003)
Curr. Opin. Pharmacol.
, vol.3
, pp. 192-197
-
-
Joseph, S.B.1
Tontonoz, P.2
-
56
-
-
0037188553
-
Synthetic LXR ligand inhibits the development of atherosclerosis in mice
-
Joseph S.B. McKilligin E. Pei L. Watson M.A. Collins A.R. Laffitte B.A. Chen M. Noh G. Goodman J. Hagger G.N. et al. Synthetic LXR ligand inhibits the development of atherosclerosis in mice Proc Natl Acad Sci U S A 99 2002 7604-7609
-
(2002)
Proc. Natl. Acad. Sci. U S A
, vol.99
, pp. 7604-7609
-
-
Joseph, S.B.1
McKilligin, E.2
Pei, L.3
Watson, M.A.4
Collins, A.R.5
Laffitte, B.A.6
Chen, M.7
Noh, G.8
Goodman, J.9
Hagger, G.N.10
-
57
-
-
0037015013
-
Identification of macrophage liver X receptors as inhibitors of atherosclerosis
-
Tangirala R.K. Bischoff E.D. Joseph S.B. Wagner B.L. Walczak R. Laffitte B.A. Daige C.L. Thomas D. Heyman R.A. Mangelsdorf D.J. et al. Identification of macrophage liver X receptors as inhibitors of atherosclerosis Proc Natl Acad Sci U S A 99 2002 11896-11901
-
(2002)
Proc. Natl. Acad. Sci. U S A
, vol.99
, pp. 11896-11901
-
-
Tangirala, R.K.1
Bischoff, E.D.2
Joseph, S.B.3
Wagner, B.L.4
Walczak, R.5
Laffitte, B.A.6
Daige, C.L.7
Thomas, D.8
Heyman, R.A.9
Mangelsdorf, D.J.10
-
59
-
-
0033552883
-
Atherosclerosis - An inflammatory disease
-
Ross R. Atherosclerosis - an inflammatory disease N Engl J Med 340 1999 115-126
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
60
-
-
0038662737
-
Effects of MF-tricyclic, a selective cyclooxygenase-2 inhibitor, on atherosclerosis progression and susceptibility to cytomegalovirus replication in apolipoprotein-E knockout mice
-
Rott D. Zhu J. Burnett M.S. Zhou Y.F. Zalles-Ganley A. Ogunmakinwa J. Epstein S.E. Effects of MF-tricyclic, a selective cyclooxygenase-2 inhibitor, on atherosclerosis progression and susceptibility to cytomegalovirus replication in apolipoprotein-E knockout mice J Am Coll Cardiol 41 2003 1812-1819
-
(2003)
J. Am. Coll. Cardiol.
, vol.41
, pp. 1812-1819
-
-
Rott, D.1
Zhu, J.2
Burnett, M.S.3
Zhou, Y.F.4
Zalles-Ganley, A.5
Ogunmakinwa, J.6
Epstein, S.E.7
-
61
-
-
12244282459
-
No effect of cyclooxygenase inhibition on plaque size in atherosclerosis-prone mice
-
Olesen M. Kwong E. Meztli A. Kontny F. Seljeflot I. Arnesen H. Lyngdorf L. Falk E. No effect of cyclooxygenase inhibition on plaque size in atherosclerosis-prone mice Scand Cardiovasc J 36 2002 362-367
-
(2002)
Scand. Cardiovasc. J
, vol.36
, pp. 362-367
-
-
Olesen, M.1
Kwong, E.2
Meztli, A.3
Kontny, F.4
Seljeflot, I.5
Arnesen, H.6
Lyngdorf, L.7
Falk, E.8
-
63
-
-
0035866401
-
Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor
-
Oshima M. Murai N. Kargman S. Arguello M. Luk P. Kwong E. Taketo M.M. Evans J.F. Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor Cancer Res 61 2001 1733-1740
-
(2001)
Cancer Res.
, vol.61
, pp. 1733-1740
-
-
Oshima, M.1
Murai, N.2
Kargman, S.3
Arguello, M.4
Luk, P.5
Kwong, E.6
Taketo, M.M.7
Evans, J.F.8
-
64
-
-
0033594911
-
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
-
Warner T.D. Giuliano F. Vojnovic I. Bukasa A. Mitchell J.A. Vane J.R. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis Proc Natl Acad Sci U S A 96 1999 7563-7568
-
(1999)
Proc. Natl. Acad. Sci. U S A
, vol.96
, pp. 7563-7568
-
-
Warner, T.D.1
Giuliano, F.2
Vojnovic, I.3
Bukasa, A.4
Mitchell, J.A.5
Vane, J.R.6
-
65
-
-
0030733305
-
Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays
-
Riendeau D. Charleson S. Cromlish W. Mancini J.A. Wong E. Guay J. Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays Can J Physiol Pharmacol 75 1997 1088-1095
-
(1997)
Can. J. Physiol. Pharmacol.
, vol.75
, pp. 1088-1095
-
-
Riendeau, D.1
Charleson, S.2
Cromlish, W.3
Mancini, J.A.4
Wong, E.5
Guay, J.6
-
66
-
-
0032788729
-
1Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3- phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles
-
Chan C.C. Boyce S. Brideau C. Charleson S. Cromlish W. Ethier D. Evans J. Ford-Hutchinson A.W. Forrest M.J. Gauthier J.Y. et al. Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3- phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles J Pharmacol Exp Ther 290 1999 551-560
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.290
, pp. 551-560
-
-
Chan, C.C.1
Boyce, S.2
Brideau, C.3
Charleson, S.4
Cromlish, W.5
Ethier, D.6
Evans, J.7
Ford-Hutchinson, A.W.8
Forrest, M.J.9
Gauthier, J.Y.10
-
67
-
-
0028862192
-
Quantitation of atherosclerosis in murine models: Correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice
-
Tangirala R.K. Rubin E.M. Palinski W. Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice J Lipid Res 36 1995 2320-2328
-
(1995)
J. Lipid. Res.
, vol.36
, pp. 2320-2328
-
-
Tangirala, R.K.1
Rubin, E.M.2
Palinski, W.3
-
70
-
-
0034714215
-
Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice
-
Babaev V.R. Patel M.B. Semenkovich C.F. Fazio S. Linton M.F. Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice J Biol Chem 275 2000 26293-26299
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26293-26299
-
-
Babaev, V.R.1
Patel, M.B.2
Semenkovich, C.F.3
Fazio, S.4
Linton, M.F.5
-
71
-
-
0031013395
-
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs
-
Lehmann J.M. Lenhard J.M. Oliver B.B. Ringold G.M. Kliewer S.A. Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs J Biol Chem 272 1997 3406-3410
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
Ringold, G.M.4
Kliewer, S.A.5
-
72
-
-
0028944150
-
Prevention of atherosclerosis in apoE deficient mice by bone marrow transplantation
-
Linton M.F. Atkinson J.B. Fazio S. Prevention of atherosclerosis in apoE deficient mice by bone marrow transplantation Science 267 1995 1034-1037
-
(1995)
Science
, vol.267
, pp. 1034-1037
-
-
Linton, M.F.1
Atkinson, J.B.2
Fazio, S.3
-
73
-
-
0032892490
-
Macrophages, lipoprotein metabolism, and atherosclerosis: Insights from murine bone marrow transplantation studies
-
Linton M.F. Fazio S. Macrophages, lipoprotein metabolism, and atherosclerosis: insights from murine bone marrow transplantation studies Curr Opin Lipidol 10 1999 97-105
-
(1999)
Curr. Opin. Lipidol.
, vol.10
, pp. 97-105
-
-
Linton, M.F.1
Fazio, S.2
-
74
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
-
VIGOR Study Group
-
Bombardier C. Laine L. Reicin A. Shapiro D. Burgos-Vargas R. Davis B. Day R. Ferraz M.B. Hawkey C.J. Hochberg M.C. et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group N Engl J Med 343 2000 1520-1528
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
Shapiro, D.4
Burgos-Vargas, R.5
Davis, B.6
Day, R.7
Ferraz, M.B.8
Hawkey, C.J.9
Hochberg, M.C.10
-
75
-
-
0037182025
-
Selective COX-2 inhibitors, NSAIDs, aspirin, and myocardial infarction
-
Dalen J.E. Selective COX-2 inhibitors, NSAIDs, aspirin, and myocardial infarction Arch Intern Med 162 2002 1091-1092
-
(2002)
Arch. Intern. Med.
, vol.162
, pp. 1091-1092
-
-
Dalen, J.E.1
-
76
-
-
0035818601
-
Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib
-
Konstam M.A. Weir M.R. Reicin A. Shapiro D. Sperling R.S. Barr E. Gertz B.J. Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib Circulation 104 2001 2280-2288
-
(2001)
Circulation
, vol.104
, pp. 2280-2288
-
-
Konstam, M.A.1
Weir, M.R.2
Reicin, A.3
Shapiro, D.4
Sperling, R.S.5
Barr, E.6
Gertz, B.J.7
-
77
-
-
0037081649
-
Comparison of cardiovascular thrombotic events in patients with osteoarthritis treated with rofecoxib versus nonselective nonsteroidal anti-inflammatory drugs (ibuprofen, diclofenac, and nabumetone)
-
Reicin A.S. Shapiro D. Sperling R.S. Barr E. Yu Q. Comparison of cardiovascular thrombotic events in patients with osteoarthritis treated with rofecoxib versus nonselective nonsteroidal anti-inflammatory drugs (ibuprofen, diclofenac, and nabumetone) Am J Cardiol 89 2002 204-209
-
(2002)
Am. J. Cardiol.
, vol.89
, pp. 204-209
-
-
Reicin, A.S.1
Shapiro, D.2
Sperling, R.S.3
Barr, E.4
Yu, Q.5
-
78
-
-
0037027050
-
COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease
-
Ray W.A. Stein C.M. Daugherty J.R. Hall K. Arbogast P.G. Griffin M.R. COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease Lancet 360 2002 1071-1073
-
(2002)
Lancet
, vol.360
, pp. 1071-1073
-
-
Ray, W.A.1
Stein, C.M.2
Daugherty, J.R.3
Hall, K.4
Arbogast, P.G.5
Griffin, M.R.6
-
79
-
-
0034644396
-
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
-
Silverstein F.E. Faich G. Goldstein J.L. Simon L.S. Pincus T. Whelton A. Makuch R. Eisen G. Agrawal N.M. Stenson W.F. et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial. Celecoxib Long-term Arthritis Safety Study JAMA 284 2000 1247-1255
-
(2000)
JAMA
, vol.284
, pp. 1247-1255
-
-
Silverstein, F.E.1
Faich, G.2
Goldstein, J.L.3
Simon, L.S.4
Pincus, T.5
Whelton, A.6
Makuch, R.7
Eisen, G.8
Agrawal, N.M.9
Stenson, W.F.10
-
80
-
-
0041562646
-
Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxib
-
White W.B. Faich G. Borer J.S. Makuch R.W. Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxib Am J Cardiol 92 2003 411-418
-
(2003)
Am. J. Cardiol.
, vol.92
, pp. 411-418
-
-
White, W.B.1
Faich, G.2
Borer, J.S.3
Makuch, R.W.4
-
81
-
-
0037469296
-
Selective COX-2 inhibition improves endothelial function in coronary artery disease
-
Chenevard R. Hurlimann D. Bechir M. Enseleit F. Spieker L. Hermann M. Riesen W. Gay S. Gay R.E. Neidhart M. et al. Selective COX-2 inhibition improves endothelial function in coronary artery disease Circulation 107 2003 405-409
-
(2003)
Circulation
, vol.107
, pp. 405-409
-
-
Chenevard, R.1
Hurlimann, D.2
Bechir, M.3
Enseleit, F.4
Spieker, L.5
Hermann, M.6
Riesen, W.7
Gay, S.8
Gay, R.E.9
Neidhart, M.10
-
82
-
-
0037047119
-
Efficacy assessment of meloxicam, a preferential cyclooxygenase-2 inhibitor, in acute coronary syndromes without ST-segment elevation: The Nonsteroidal Anti-Inflammatory Drugs in Unstable Angina Treatment-2 (NUT-2) pilot study
-
Altman R. Luciardi H.L. Muntaner J. Del Rio F. Berman S.G. Lopez R. Gonzalez C. Efficacy assessment of meloxicam, a preferential cyclooxygenase-2 inhibitor, in acute coronary syndromes without ST-segment elevation: the Nonsteroidal Anti-Inflammatory Drugs in Unstable Angina Treatment-2 (NUT-2) pilot study Circulation 106 2002 191-195
-
(2002)
Circulation
, vol.106
, pp. 191-195
-
-
Altman, R.1
Luciardi, H.L.2
Muntaner, J.3
Del Rio, F.4
Berman, S.G.5
Lopez, R.6
Gonzalez, C.7
-
83
-
-
0035934070
-
Risk of cardiovascular events associated with selective COX-2 inhibitors
-
Mukherjee D. Nissen S.E. Topol E.J. Risk of cardiovascular events associated with selective COX-2 inhibitors JAMA 286 2001 954-959
-
(2001)
JAMA
, vol.286
, pp. 954-959
-
-
Mukherjee, D.1
Nissen, S.E.2
Topol, E.J.3
-
84
-
-
0035833502
-
The Coxibs, selective inhibitors of cyclooxygenase-2
-
FitzGerald G.A.Patrono C.The Coxibs, selective inhibitors of cyclooxygenase-2 N Engl J Med 345 2001 433-442
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 433-442
-
-
FitzGerald, G.A.1
Patrono, C.2
|