Pharmaceutical Prospects for RNA Interference

Pharmaceutical Research

Volumn 21, Issue 1, 2004, Pages 1-7

  Schiffelers, Raymond M ^a,b   Woodle, Martin C ^b   Scaria, Puthupparampil ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b Intradigm Corporation   (United States)

Author keywords

Drug delivery; Gene silencing; Nucleic acids; RNA interference; siRNA

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CHLORIDE; DNA; DOUBLE STRANDED RNA; GREEN FLUORESCENT PROTEIN; LIPID; MESSENGER RNA; N (1,2,3 DIOLEOYLOXY)PROPYL N,N,N TRIMETHYLAMMONIUM CHLORIDE; NUCLEIC ACID; NUCLEOSIDE; POLYAMINE; POLYCATION; PROTEIN; PROTEIN P53; RNA; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS VECTOR;

ADENOVIRUS; ALLELE; BACULOVIRUS; BASE PAIRING; CELL ADHESION; CELL MEMBRANE; CELL TYPE; CYTOTOXICITY; DISEASE CONTROL; DNA REPAIR; DRUG EFFICACY; DRUG SAFETY; ELECTRICITY; ELECTROPORATION; GENE CONTROL; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE FUNCTION; GENE GUN; GENE SILENCING; GENE THERAPY; GENE VECTOR; GENETIC CODE; GENETIC TRANSFECTION; HEPATITIS; HERPES VIRUS; HOMEOSTASIS; HUMAN; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; LENTIVIRINAE; LIVER FAILURE; MALIGNANT NEOPLASTIC DISEASE; MODULATION; NONHUMAN; PARTICLE SIZE; POINT MUTATION; POLYMERIZATION; PRESSURE; PRIORITY JOURNAL; REPORTER GENE; RETROVIRUS; REVIEW; RNA BINDING; RNA DEGRADATION; RNA INTERFERENCE; RNA SEQUENCE; RNA STABILITY; RNA SYNTHESIS; SEPSIS; TECHNIQUE; VALIDATION PROCESS; VIRION;

ANIMALS; DRUG DELIVERY SYSTEMS; HUMANS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TECHNOLOGY, PHARMACEUTICAL;

EID: 1642498310     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000012145.49054.6c     Document Type: Review

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