-
1
-
-
0029024475
-
Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
-
Guo S., Kemphues K.J. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell. 81:1995;611-620.
-
(1995)
Cell
, vol.81
, pp. 611-620
-
-
Guo, S.1
Kemphues, K.J.2
-
2
-
-
0032417618
-
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans
-
Montgomery M.K., Xu S., Fire A. RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 95(26):1998;15502-15507.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.26
, pp. 15502-15507
-
-
Montgomery, M.K.1
Xu, S.2
Fire, A.3
-
3
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A.et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 391(6669):1998;744-745.
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 744-745
-
-
Fire, A.1
-
4
-
-
0034676448
-
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
-
Gonczy P.et al. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature. 408(6810):2000;331-336.
-
(2000)
Nature
, vol.408
, Issue.6810
, pp. 331-336
-
-
Gonczy, P.1
-
5
-
-
0034676457
-
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
-
Fraser A.G.et al. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature. 408(6810):1999;325-330.
-
(1999)
Nature
, vol.408
, Issue.6810
, pp. 325-330
-
-
Fraser, A.G.1
-
6
-
-
0030267493
-
RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants
-
Baulcombe D. RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants. Plant Mol. Biol. 32(1-2):1996;79-88.
-
(1996)
Plant Mol. Biol.
, vol.32
, Issue.1-2
, pp. 79-88
-
-
Baulcombe, D.1
-
7
-
-
0029102514
-
How and why do plants inactivate homologous (trans)genes?
-
Matzke M.A., Matzke A.J. How and why do plants inactivate homologous (trans)genes? Plant Physiology. 107(3):1995;679-685.
-
(1995)
Plant Physiology
, vol.107
, Issue.3
, pp. 679-685
-
-
Matzke, M.A.1
Matzke, A.J.2
-
8
-
-
0030927776
-
Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA
-
Angell S.M., Baulcombe D. Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA. EMBO J. 16(12):1997;3675-3684.
-
(1997)
EMBO J.
, vol.16
, Issue.12
, pp. 3675-3684
-
-
Angell, S.M.1
Baulcombe, D.2
-
9
-
-
0028898232
-
Cytoplasmic inhibition of carotenoid biosynthesis with virus-derived RNA
-
Kumagai M.H.et al. Cytoplasmic inhibition of carotenoid biosynthesis with virus-derived RNA. Proc. Natl. Acad. Sci. USA. 92(5):1995;1679-1683.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, Issue.5
, pp. 1679-1683
-
-
Kumagai, M.H.1
-
10
-
-
0028031830
-
RNA-directed de novo methylation of genomic sequences in plants
-
Wassenegger M.et al. RNA-directed de novo methylation of genomic sequences in plants. Cell. 76(3):1994;567-576.
-
(1994)
Cell
, vol.76
, Issue.3
, pp. 567-576
-
-
Wassenegger, M.1
-
11
-
-
0031826316
-
Double-stranded RNA as a mediator in sequence-specific genetic silencing and co-suppression
-
Montgomery M.K., Fire A. Double-stranded RNA as a mediator in sequence-specific genetic silencing and co-suppression. Trends Genet. 14(7):1998;255-258.
-
(1998)
Trends Genet.
, vol.14
, Issue.7
, pp. 255-258
-
-
Montgomery, M.K.1
Fire, A.2
-
12
-
-
0030875953
-
Systemic acquired silencing: Transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions
-
Palauqui J.C.et al. Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO J. 16(15):1997;4738-4745.
-
(1997)
EMBO J.
, vol.16
, Issue.15
, pp. 4738-4745
-
-
Palauqui, J.C.1
-
13
-
-
0034636715
-
DsRNA-mediated gene silencing in cultured Drosophila cells: A tissue culture model for the analysis of RNA interference
-
Caplen N.J.et al. dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference. Gene. 252(1-2):2000;95-105.
-
(2000)
Gene
, vol.252
, Issue.1-2
, pp. 95-105
-
-
Caplen, N.J.1
-
14
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir S.M.et al. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20(23):2001;6877-6888.
-
(2001)
EMBO J.
, vol.20
, Issue.23
, pp. 6877-6888
-
-
Elbashir, S.M.1
-
15
-
-
0036752955
-
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
-
Schwarz D.S.et al. Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol. Cell. 10(3):2002;537-548.
-
(2002)
Mol. Cell
, vol.10
, Issue.3
, pp. 537-548
-
-
Schwarz, D.S.1
-
16
-
-
0034683099
-
Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target
-
Ui-Tei K.et al. Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target. FEBS Lett. 479(3):2000;79-82.
-
(2000)
FEBS Lett.
, vol.479
, Issue.3
, pp. 79-82
-
-
Ui-Tei, K.1
-
17
-
-
0036741817
-
Reverse genetics in Drosophila: From sequence to phenotype using UAS-RNAi transgenic flies
-
Enerly E., Larsson J., Lambertsoon A. Reverse genetics in Drosophila: from sequence to phenotype using UAS-RNAi transgenic flies. Genesis. 34(1-2):2002;152-155.
-
(2002)
Genesis
, vol.34
, Issue.1-2
, pp. 152-155
-
-
Enerly, E.1
Larsson, J.2
Lambertsoon, A.3
-
18
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl T.et al. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13(24):1999;3191-3197.
-
(1999)
Genes Dev.
, vol.13
, Issue.24
, pp. 3191-3197
-
-
Tuschl, T.1
-
19
-
-
0038387645
-
In vitro analysis of RNA interference in Drosophila melanogaster
-
Haley B., Tang G., Zamore P.D. In vitro analysis of RNA interference in Drosophila melanogaster. Methods. 4:2003;330-336.
-
(2003)
Methods
, vol.4
, pp. 330-336
-
-
Haley, B.1
Tang, G.2
Zamore, P.D.3
-
20
-
-
0034634360
-
Transgene and transposon silencing in chlamydomonas reinhardtii by a DEAH-Box RNA helicase
-
Wu-Scharf D.et al. Transgene and transposon silencing in chlamydomonas reinhardtii by a DEAH-Box RNA helicase. Science. 290:2000;1159-1163.
-
(2000)
Science
, vol.290
, pp. 1159-1163
-
-
Wu-Scharf, D.1
-
21
-
-
0035838369
-
Double-stranded RNA-mediated silencing of genomic tandem repeats and transposale elements in the D. melanogaster germline
-
Aravin A.A. Double-stranded RNA-mediated silencing of genomic tandem repeats and transposale elements in the D. melanogaster germline. Curr. Biol. 11:2001;1017-1027.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1017-1027
-
-
Aravin, A.A.1
-
22
-
-
0034673645
-
A genetic link between co-suppression and RNA interference in C. elegans
-
Ketting R.F., Plasterk R.H. A genetic link between co-suppression and RNA interference in C. elegans. Nature. 404:2000;296-298.
-
(2000)
Nature
, vol.404
, pp. 296-298
-
-
Ketting, R.F.1
Plasterk, R.H.2
-
23
-
-
0032739015
-
Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD
-
Ketting R.F.et al. Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell. 99:1999;133-141.
-
(1999)
Cell
, vol.99
, pp. 133-141
-
-
Ketting, R.F.1
-
24
-
-
0037072606
-
Molecular biology. RNAi and heterochromatin - A hushed-up affair
-
Allshire R. Molecular biology. RNAi and heterochromatin - a hushed-up affair. Science. 297(5588):2002;1818-1819.
-
(2002)
Science
, vol.297
, Issue.5588
, pp. 1818-1819
-
-
Allshire, R.1
-
25
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir S.M.et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411(6836):2001;494-498.
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
-
26
-
-
0037012663
-
Antisense-RNA regulation and RNA interference
-
Brantl S. Antisense-RNA regulation and RNA interference. Biochim. Biophys. Acta. 1575(1-3):2002;15-25.
-
(2002)
Biochim. Biophys. Acta
, vol.1575
, Issue.1-3
, pp. 15-25
-
-
Brantl, S.1
-
28
-
-
0029993528
-
Perspective series: Molecular medicine in genetically engineered animals
-
Nagy A., Rossant J. Perspective series: molecular medicine in genetically engineered animals. J. Clin. Invest. 97(6):1999;1360-1365.
-
(1999)
J. Clin. Invest.
, vol.97
, Issue.6
, pp. 1360-1365
-
-
Nagy, A.1
Rossant, J.2
-
29
-
-
0037280401
-
RNA interference may be more potent than antisense RNA in human cancer cell lines
-
Aoki Y.et al. RNA interference may be more potent than antisense RNA in human cancer cell lines. Clinical and Experimental Pharmacology and Physiology. 30:2003;96-102.
-
(2003)
Clinical and Experimental Pharmacology and Physiology
, vol.30
, pp. 96-102
-
-
Aoki, Y.1
-
30
-
-
24144445346
-
Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells
-
Miyagishi M., Hayashi M., Taira K. Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells. Antisense Nucleic Acid Drug Develop. 13(1):2003;1-7.
-
(2003)
Antisense Nucleic Acid Drug Develop.
, vol.13
, Issue.1
, pp. 1-7
-
-
Miyagishi, M.1
Hayashi, M.2
Taira, K.3
-
31
-
-
0035984059
-
Endogenous and silencing-associated small RNAs in plants
-
Llave C.et al. Endogenous and silencing-associated small RNAs in plants. Plant Cell. 14(7):2002;1605-1619.
-
(2002)
Plant Cell
, vol.14
, Issue.7
, pp. 1605-1619
-
-
Llave, C.1
-
32
-
-
0037087780
-
MiRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
-
Mourelatos Z.et al. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 16(6):2002;720-728.
-
(2002)
Genes Dev.
, vol.16
, Issue.6
, pp. 720-728
-
-
Mourelatos, Z.1
-
33
-
-
0036534284
-
MicroRNAs: Deviants no longer
-
Pasquinelli A.E. MicroRNAs: deviants no longer. Trends Genet. 18(4):2002;171-173.
-
(2002)
Trends Genet.
, vol.18
, Issue.4
, pp. 171-173
-
-
Pasquinelli, A.E.1
-
34
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 75:1993;843-854.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
35
-
-
0034597777
-
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
-
Pasquinelli A.E.et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 408(6808):2000;86-89.
-
(2000)
Nature
, vol.408
, Issue.6808
, pp. 86-89
-
-
Pasquinelli, A.E.1
-
36
-
-
0032443562
-
A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal
-
Cox D.N.et al. A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev. 12:1998;3715-3727.
-
(1998)
Genes Dev.
, vol.12
, pp. 3715-3727
-
-
Cox, D.N.1
-
37
-
-
0034877670
-
RNA interference: Listening to the sound of silence
-
Zamore P.D. RNA interference: listening to the sound of silence. Nat. Struct. Biol. 8(9):2001;746-750.
-
(2001)
Nat. Struct. Biol.
, vol.8
, Issue.9
, pp. 746-750
-
-
Zamore, P.D.1
-
38
-
-
0037123601
-
Ancient pathways programmed by small RNAs
-
Zamore P.D. Ancient pathways programmed by small RNAs. Science. 296(5571):2002;1265-1269.
-
(2002)
Science
, vol.296
, Issue.5571
, pp. 1265-1269
-
-
Zamore, P.D.1
-
39
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir S.M., Lendeckel W., Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15(2):2001;188-200.
-
(2001)
Genes Dev.
, vol.15
, Issue.2
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
40
-
-
0036975958
-
The effectiveness of double-stranded short inhibitory RNAs (siRNAs) may depend on the method of transfection
-
Walters D.K., Jelinek D.F. The effectiveness of double-stranded short inhibitory RNAs (siRNAs) may depend on the method of transfection. Antisense Nucleic Acid Drug Develop. 12:2002;411-418.
-
(2002)
Antisense Nucleic Acid Drug Develop.
, vol.12
, pp. 411-418
-
-
Walters, D.K.1
Jelinek, D.F.2
-
41
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee N.S.et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol. 20(5):2002;500-505.
-
(2002)
Nat. Biotechnol.
, vol.20
, Issue.5
, pp. 500-505
-
-
Lee, N.S.1
-
42
-
-
0036251639
-
Effective expression of small interfering RNA in human cells
-
Paul C.P.et al. Effective expression of small interfering RNA in human cells. Nat. Biotechnol. 20(5):2002;505-508.
-
(2002)
Nat. Biotechnol.
, vol.20
, Issue.5
, pp. 505-508
-
-
Paul, C.P.1
-
43
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui G.et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA. 99(8):2002;5515-5520.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.8
, pp. 5515-5520
-
-
Sui, G.1
-
44
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison P.J.et al. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16(8):2002;948-958.
-
(2002)
Genes Dev.
, vol.16
, Issue.8
, pp. 948-958
-
-
Paddison, P.J.1
-
45
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp T.R., Bernards R., Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296(5567):2002;550-553.
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
46
-
-
0141663731
-
Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs
-
Yokota T.et al. Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs. EMBO J. 4(6):2003;1-7.
-
(2003)
EMBO J.
, vol.4
, Issue.6
, pp. 1-7
-
-
Yokota, T.1
-
47
-
-
0037069417
-
Retroviral delivery of small interfering RNA into primary cells
-
Barton G.M., Medzhitov R. Retroviral delivery of small interfering RNA into primary cells. Proc. Natl. Acad. Sci. USA. 99(23):2002;14943-14945.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.23
, pp. 14943-14945
-
-
Barton, G.M.1
Medzhitov, R.2
-
48
-
-
0002675296
-
Retrovirus-delivered siRNA
-
Devroe E., Silver P.A. Retrovirus-delivered siRNA. BMC Biotechnol. 2(15):2002;1-5.
-
(2002)
BMC Biotechnol.
, vol.2
, Issue.15
, pp. 1-5
-
-
Devroe, E.1
Silver, P.A.2
-
49
-
-
0344375083
-
Lentivirus-delivered stable gene silencing by RNAi in primary cells
-
Stewart S.A.et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA. 9(4):2003;493-501.
-
(2003)
RNA
, vol.9
, Issue.4
, pp. 493-501
-
-
Stewart, S.A.1
-
50
-
-
0036976008
-
Lentiviral-mediated RNA interference
-
Abbas-Terki T.et al. Lentiviral-mediated RNA interference. Hum. Gene Ther. 13:2002;2197-2201.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 2197-2201
-
-
Abbas-Terki, T.1
-
51
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells, and transgenic mice by RNA interference
-
Rubinson D.A.et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells, and transgenic mice by RNA interference. Nat. Genet. 33:2003;401-406.
-
(2003)
Nat. Genet.
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
-
52
-
-
0037468660
-
Gene silencing by adenovirus-delivered siRNA
-
Shen C.et al. Gene silencing by adenovirus-delivered siRNA. FEBS Lett. (539):2003;111-114.
-
(2003)
FEBS Lett.
, Issue.539
, pp. 111-114
-
-
Shen, C.1
-
53
-
-
0029949294
-
Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: A comparative study
-
Ilves H.et al. Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: a comparative study. Gene. 171(2):1996;203-208.
-
(1996)
Gene
, vol.171
, Issue.2
, pp. 203-208
-
-
Ilves, H.1
-
54
-
-
0024465085
-
Transcription of a human U6 small nuclear RNA gene in vivo withstands deletion of intragenic sequences but not of an upstream TATATA box
-
Kunkel G.R., Pederson T. Transcription of a human U6 small nuclear RNA gene in vivo withstands deletion of intragenic sequences but not of an upstream TATATA box. Nucleic Acids Res. 17(18):1989;7371-7379.
-
(1989)
Nucleic Acids Res.
, vol.17
, Issue.18
, pp. 7371-7379
-
-
Kunkel, G.R.1
Pederson, T.2
-
55
-
-
0035875333
-
An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene
-
Myslinski E.et al. An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene. Nucleic Acids Res. 29(12):2001;2502-2509.
-
(2001)
Nucleic Acids Res.
, vol.29
, Issue.12
, pp. 2502-2509
-
-
Myslinski, E.1
-
56
-
-
0037417136
-
Identification of NF-kappa B-regulated genes induced by TNF alpha utilizing expression profiling and RNA interference
-
Zhou A.et al. Identification of NF-kappa B-regulated genes induced by TNF alpha utilizing expression profiling and RNA interference. Oncogene. 22(13):2003;2054-2064.
-
(2003)
Oncogene
, vol.22
, Issue.13
, pp. 2054-2064
-
-
Zhou, A.1
-
57
-
-
4243754537
-
Confirming specificity of RNAi in mammalian cells
-
Lassus P., Rodriguez J., Lazebnik Y. Confirming specificity of RNAi in mammalian cells. Sci. STKE. 2002(147):2002;PL13.
-
(2002)
Sci. STKE
, vol.2002
, Issue.147
, pp. 13
-
-
Lassus, P.1
Rodriguez, J.2
Lazebnik, Y.3
-
58
-
-
0037107886
-
RNAi: Gene-silencing in therapeutic intervention
-
Shuey D.J., McCallus D.E., Giordano T. RNAi: gene-silencing in therapeutic intervention. Drug Discov. Today. 7(20):2002;1040-1046.
-
(2002)
Drug Discov. Today
, vol.7
, Issue.20
, pp. 1040-1046
-
-
Shuey, D.J.1
McCallus, D.E.2
Giordano, T.3
-
59
-
-
0037063364
-
Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)
-
Heinonen J.E., Smith C.I., Nore B.F. Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA). FEBS Lett. 527(1-3):2002;274-278.
-
(2002)
FEBS Lett.
, vol.527
, Issue.1-3
, pp. 274-278
-
-
Heinonen, J.E.1
Smith, C.I.2
Nore, B.F.3
-
60
-
-
0037059054
-
Biliverdin reductase: A major physiologic cytoprotectant
-
Baranano D.E.et al. Biliverdin reductase: a major physiologic cytoprotectant. Proc. Natl. Acad. Sci. USA. 99(25):2002;16093-16098.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.25
, pp. 16093-16098
-
-
Baranano, D.E.1
-
61
-
-
0037132736
-
Effect of RNA silencing of polo-like kinase 1 (PLK1) on apoptosis and spindle formation in human cancer cells
-
Spankuch-Schmitt B.et al. Effect of RNA silencing of polo-like kinase 1 (PLK1) on apoptosis and spindle formation in human cancer cells. J. Natl. Cancer Inst. 94(24):2002;1863-1877.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, Issue.24
, pp. 1863-1877
-
-
Spankuch-Schmitt, B.1
-
63
-
-
0037441756
-
Specific inhibition of bcr-abl gene expression by small interfering RNA
-
Scherr M.et al. Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood. 101(4):2003;1566-1569.
-
(2003)
Blood
, vol.101
, Issue.4
, pp. 1566-1569
-
-
Scherr, M.1
-
64
-
-
0037158901
-
Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
-
Wilda M.et al. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene. 21(37):2002;5716-5724.
-
(2002)
Oncogene
, vol.21
, Issue.37
, pp. 5716-5724
-
-
Wilda, M.1
-
65
-
-
0038047685
-
AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells
-
Heidenreich O.et al. AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells. Blood. 101:2003;3157-3163.
-
(2003)
Blood
, vol.101
, pp. 3157-3163
-
-
Heidenreich, O.1
-
66
-
-
0037144437
-
A novel myc target gene, mina53, that is involved in cell proliferation
-
Tsuneoka M.et al. A novel myc target gene, mina53, that is involved in cell proliferation. J. Biol. Chem. 277(38):2002;35450-35459.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.38
, pp. 35450-35459
-
-
Tsuneoka, M.1
-
67
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp T.R., Bernards R., Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell. 2(3):2002;243-247.
-
(2002)
Cancer Cell
, vol.2
, Issue.3
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
68
-
-
0037866466
-
The PML gene is not involved in the regulation of MHC class I expression in human cell lines
-
Bruno S.et al. The PML gene is not involved in the regulation of MHC class I expression in human cell lines. Blood. 101:2003;3514-3519.
-
(2003)
Blood
, vol.101
, pp. 3514-3519
-
-
Bruno, S.1
-
69
-
-
0037026601
-
Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference
-
Jiang M., Milner J. Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference. Oncogene. 21(39):2002;6041-6048.
-
(2002)
Oncogene
, vol.21
, Issue.39
, pp. 6041-6048
-
-
Jiang, M.1
Milner, J.2
-
70
-
-
0037112508
-
Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation
-
Peng Y.et al. Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation. Cancer Res. 62(22):2002;6400-6404.
-
(2002)
Cancer Res.
, vol.62
, Issue.22
, pp. 6400-6404
-
-
Peng, Y.1
-
71
-
-
0036529825
-
Expression of cyclic adenosine monophosphate response-element binding protein in acute leukemia
-
Crans-Vargas H.N.et al. Expression of cyclic adenosine monophosphate response-element binding protein in acute leukemia. Blood. 99(7):2002;2617-2619.
-
(2002)
Blood
, vol.99
, Issue.7
, pp. 2617-2619
-
-
Crans-Vargas, H.N.1
-
72
-
-
0034775750
-
Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells
-
Yang S.et al. Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells. Mol. Cell. Biol. 21:2001;7807-7816.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7807-7816
-
-
Yang, S.1
-
73
-
-
0037370309
-
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
-
Hemann M.T.et al. An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nat. Genet. 33(3):2003;396-400.
-
(2003)
Nat. Genet.
, vol.33
, Issue.3
, pp. 396-400
-
-
Hemann, M.T.1
-
74
-
-
0036468677
-
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
-
Lois C.et al. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science. 295:2002;868-872.
-
(2002)
Science
, vol.295
, pp. 868-872
-
-
Lois, C.1
-
75
-
-
0037133212
-
Transgenesis by lentiviral vectors: Lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos
-
Pfiefer A.et al. Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos. Proc. Natl. Acad. Sci. USA. 99:2002;2140-2145.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2140-2145
-
-
Pfiefer, A.1
-
76
-
-
0036891843
-
RNA interference directed against viral and cellular targets inhibits human immunodeficiency virus type 1 replication
-
Surabhi R.M., Gaynor R.B. RNA interference directed against viral and cellular targets inhibits human immunodeficiency virus type 1 replication. J. Virol. 76(24):2002;12963-12973.
-
(2002)
J. Virol.
, vol.76
, Issue.24
, pp. 12963-12973
-
-
Surabhi, R.M.1
Gaynor, R.B.2
-
77
-
-
0036066508
-
SiRNA-directed inhibition of HIV-1 infection
-
Novina C.D.et al. siRNA-directed inhibition of HIV-1 infection. Nat. Med. 8(7):2002;681-686.
-
(2002)
Nat. Med.
, vol.8
, Issue.7
, pp. 681-686
-
-
Novina, C.D.1
-
78
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin X.F.et al. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. USA. 100(1):2003;183-188.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.1
, pp. 183-188
-
-
Qin, X.F.1
-
79
-
-
0036840946
-
RNA interference: A promising approach to antiviral therapy?
-
Silva J.M., Hammond S.M., Hannon G.J. RNA interference: a promising approach to antiviral therapy? Trends Mol. Med. 8(11):2002;505-508.
-
(2002)
Trends Mol. Med.
, vol.8
, Issue.11
, pp. 505-508
-
-
Silva, J.M.1
Hammond, S.M.2
Hannon, G.J.3
-
80
-
-
0036963990
-
Rotavirus gene silencing by small interfering RNAs
-
Dector M.A.et al. Rotavirus gene silencing by small interfering RNAs. EMBO Rep. 3(12):2002;1175-1180.
-
(2002)
EMBO Rep.
, vol.3
, Issue.12
, pp. 1175-1180
-
-
Dector, M.A.1
-
81
-
-
0037418322
-
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
-
Ge Q.et al. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. PNAS. 100(5):2003;2718-2723.
-
(2003)
PNAS
, vol.100
, Issue.5
, pp. 2718-2723
-
-
Ge, Q.1
-
82
-
-
0036049784
-
Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum
-
Malhotra P.et al. Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum. Mol. Microbiol. 45(5):2002;1245-1254.
-
(2002)
Mol. Microbiol.
, vol.45
, Issue.5
, pp. 1245-1254
-
-
Malhotra, P.1
-
83
-
-
0036188983
-
RNA interference in the pathogenic fungus Cryptococcus neoformans
-
Liu H.et al. RNA interference in the pathogenic fungus Cryptococcus neoformans. Genetics. 160(2):2002;463-470.
-
(2002)
Genetics
, vol.160
, Issue.2
, pp. 463-470
-
-
Liu, H.1
-
84
-
-
0036792769
-
Fragile X-related protein and VIG associate with the RNA interference machinery
-
Caudy A.A.et al. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev. 16(19):2002;2491-2496.
-
(2002)
Genes Dev.
, vol.16
, Issue.19
, pp. 2491-2496
-
-
Caudy, A.A.1
-
85
-
-
0037164732
-
RNA interference: The fragile X syndrome connection
-
Carthew R.W. RNA interference: the fragile X syndrome connection. Curr. Biol. 12(24):2002;R852-R854.
-
(2002)
Curr. Biol.
, vol.12
, Issue.24
-
-
Carthew, R.W.1
-
86
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song E.et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. 2003.
-
(2003)
Nat. Med.
-
-
Song, E.1
-
87
-
-
0037452812
-
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
-
Tiscornia G.et al. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA. 100(4):2003;1844-1848.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.4
, pp. 1844-1848
-
-
Tiscornia, G.1
-
88
-
-
10744219596
-
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
-
van de Wetering M.et al. Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector. EMBO J. 4(6):2003;609-615.
-
(2003)
EMBO J.
, vol.4
, Issue.6
, pp. 609-615
-
-
Van De Wetering, M.1
-
89
-
-
33847725190
-
Doxycycline-induced expression of sense and inverted-repeat constructs modulates phosphogluconate mutase (Pgm) gene expression in adult Drosophila melanogaster
-
Allikian M.J.et al. Doxycycline-induced expression of sense and inverted-repeat constructs modulates phosphogluconate mutase (Pgm) gene expression in adult Drosophila melanogaster. Genome Biol. 3(5):2002;1-10.
-
(2002)
Genome Biol.
, vol.3
, Issue.5
, pp. 1-10
-
-
Allikian, M.J.1
|