Gene transfer with lipospermines and polyethylenimines

Advanced Drug Delivery Reviews

Volumn 30, Issue 1-3, 1998, Pages 85-95

  Remy, Jean Serge ^a   Abdallah, Bassima ^b   Zanta, Maria Antonietta ^a   Boussif, Otmane ^a   Behr, Jean Paul ^a   Demeneix, Barbara ^b  

^a CNRS   (France)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

Cationic lipids; Cationic polymers; Exgen 500; In vitro gene delivery; In vivo gene transfer; Mammalian brain; Transfectam

Indexed keywords

BIOSYNTHESIS; BRAIN; DNA; DRUG PRODUCTS; GENES; GENETIC ENGINEERING; LIPIDS; ORGANIC POLYMERS;

CATIONIC LIPIDS; CATIONIC POLYMERS; EXGEN 500; IN VIVO GENE TRANSFER; LIPOSPERMINES; MAMMALIAN BRAIN; POLYETHYLENIMINES; TRANSFECTAM;

DRUG THERAPY;

SPERMINE;

ANIMAL EXPERIMENT; COMPLEX FORMATION; DNA TRANSFECTION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG TRANSPORT; DRUG UPTAKE; EXPRESSION VECTOR; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; TECHNIQUE;

EID: 0032473561     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(97)00109-9     Document Type: Review

References (27)

1. Behr J.P., Demeneix B.A., Loeffler J.P., Perez-Mutul J. Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA. Proc. Natl. Acad. Sci. USA. 86:1989;6982-6986.
2. Bloomfield V.A. DNA condensation. Curr. Opin. Struct. Biol. 6:1996;334-341.
3. Labat-Moleur F., Steffan A.-M., Brisson C., Perron H., Feugeas O., Furstenberger P., Oberling F., Brambilla E., Behr J.-P. An electron microscopy study into the mechanism of gene transfer with lipopolyamines. Gene Ther. 3:1996;1010-1017.
4. Barthel F., Remy J.S., Loeffler J.P., Behr J.P. Gene transfer optimization with lipospermine coated DNA. DNA Cell Biol. 12:1993;553-560.
5. J.S. Remy, C. Sirlin, J.P. Behr, Cationic amphiphiles as gene transfer vehicles, in: Philippot and F. Schuber (Eds.), Liposomes as Tools in Basic Research and Industry. CRC Press, New York, 1994, 159-169.
6. Guy-Caffey J.K., Bodepudi V., Bishop J.S., Jayaraman K., Chaudhary N. Novel polyaminolipids enhance the cellular uptake of oligonucleotides. J. Biol. Chem. 270:1995;31391-31396.
7. Lewis J.G., Lin K.-Y., Kothavale A., Flanagan W.M., Matteucci M.D., DePrince R.B., Mook R.A., Hendren R.W., Wagner R.W. A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA. Proc. Natl. Acad. Sci. USA. 93:1996;3176-3181.
8. Moradpour D., Schauer J.I., Zurawski V.R., Wands J.R., Boutin R.H. Efficient gene transfer into mammalian cells with cholesteryl-spermidine. Biochem. Biophys. Res. Commun. 221:1996;82-88.
9. Lee E.R., Marshall J., Siegel C.S., Jiang C., Yew N.S., Nichols M.R., Nietupski J.B., Ziegler R.J., Lane M., Wang K.X., Wan N.C., Scheule R.K., Harris D.J., Smith A.E., Cheng S.H. Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung. Hum. Gene Ther. 7:1996;1701-1717.
10. Remy J.S., Kichler A., Mordvinov V., Schuber F., Behr J.P. Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses. Proc. Natl. Acad. Sci. USA. 92:1995;1744-1748.
11. Behr J.P. Gene transfer with synthetic amphiphiles: prospects for gene therapy. Bioconjugate Chem. 5:1994;382-389.
12. Haensler J., Szoka F.C. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjugate Chem. 4:1993;372-379.
13. Tomalia D.A., Naylor A.M., Goddard W.A. Starburst cascade polymers: Molecular-level control of size, shape, surface chemistry, topology, and flexibility from atoms to macroscopic matter. Angew. Chem. Int. Ed. Engl. 29:1990;138-175.
14. Suh J., Paik H.J., Hwang B.K. Ionization of poly(ethylenimine) and poly(allylamine) at various pH's. Bioorg. Chem. 22:1994;318-327.
15. Chuck A.S., Clarke M.F., Palsson B.O. Retroviral infection is limited by brownian motion. Hum. Gene Ther. 7:1996;1527-1534.
16. Boussif O., Zanta M.A., Behr J.P. Optimized galenics improve in vitro gene transfer with cationic molecules up to thousand-fold. Gene Ther. 3:1996;1074-1080.
17. Boussif O., Lezoualch F., Zanta M.A., Mergny M.D., Scherman D., Demeneix B., Behr J.P. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo - polyethylenimine. Proc. Natl. Acad. Sci. USA. 92:1995;7297-7301.
18. Demeneix B.A., Abdel-Taweb H., Benoist C., Seugnet I., Behr J.P. Temporal and spatial expression of lipospermine-compacted genes transferred into chick embryos in vivo. Biotechniques. 16:1994;496-501.
19. Tsukamoto M., Ochiya T., Yoshida S., Sugimura T., Terada M. Gene transfer and expression in progeny after intravenous DNA injection into pregnant mice. Nat. Genet. 9:1995;243-248.
20. Schwartz B., Benoist C., Abdallah B., Scherman D., Behr J.-P., Demeneix B.A. Lipospermine-based gene transfer into the newborn mouse brain is optimized by a low lipospermine/DNA charge ratio. Hum. Gene Ther. 6:1995;1515-1524.
21. Philip R., Liggitt D., Philip M., Dazin P., Debs R. In vivo gene delivery. Efficient transfection of T lymphocytes in adult mice. J. Biol. Chem. 268:1993;16087-16090.
22. Thierry A.R., Lunardiiskandar Y., Bryant J.L., Rabinovich P., Gallo R.C., Mahan L.C. Systemic gene therapy: biodistribution and long-term expression of a transgene in mice. Proc. Natl. Acad. Sci. USA. 92:1995;9742-9746.
23. Aksentijevich I., Pastan I., Lunardi-Iskandar Y., Gallo R.C., Gottesman M.M., Thierry A.R. In vitro and in vivo liposome-mediated gene transfer leads to human MDR1 expression in mouse bone marrow progenitor cells. Hum. Gene Ther. 7:1996;1111-1122.
24. Schwartz B., Benoist C., Abdallah B., Rangara R., Hassan A., Scherman D., Demeneix B.A. Gene transfer by naked DNA into adult mouse brain. Gene Ther. 3:1996;405-411.
25. Abdallah B., Hassan A., Goula D., Benoist C., Behr J.-P., Demeneix B.A. A powerful non-viral vector for in vivo gene transfer in the adult mammalian brain: polyethylenimine. Gene Ther. 7:1996;1947-1954.
26. 2+ channel structure and function with antisense oligonucleotides. Mol. Cell. Neurosci. 7:1996;239-246.
27. Nelson N. Structure and morphology of the proton-ATPases. Trends Pharmacol. Sci. 12:1991;71-75.