A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes

Journal of Controlled Release

Volumn 112, Issue 2, 2006, Pages 257-270

  Werth, Stephanie ^a   Urban Klein, Beata ^a   Dai, Lige ^a   Höbel, Sabrina ^a   Grzelinski, Marius ^a   Bakowsky, Udo ^b   Czubayko, Frank ^a   Aigner, Achim ^a  

^a Fachbereich Medizin der Universitat Marburg   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

PEI; Polyethylenimine; RNAi; siRNAs; VEGF

Indexed keywords

BIODEGRADATION; CELL CULTURE; GEL PERMEATION CHROMATOGRAPHY; GENES; MOLECULAR WEIGHT;

POLYETHYLENIMINE; RNAI; SIRNAS; VEGF;

POLYETHERIMIDES;

DNA; MESSENGER RNA; POLYETHYLENEIMINE; SMALL INTERFERING RNA; VASCULOTROPIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; CELL NUCLEUS; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DEGRANULATION; DNA TRANSFECTION; DOWN REGULATION; DRUG EFFICACY; DRUG FORMULATION; DRUG TARGETING; FEMALE; FREEZE DRYING; GEL PERMEATION CHROMATOGRAPHY; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MITOSIS INHIBITION; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PRIORITY JOURNAL; PROSTATE CARCINOMA; RNA INTERFERENCE; TARGET CELL DESTRUCTION;

CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA; FREEZE DRYING; HUMANS; MOLECULAR WEIGHT; POLYETHYLENEIMINE; RNA, SMALL INTERFERING; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33646152761     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.02.009     Document Type: Article

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