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Volumn 26, Issue 1, 2007, Pages 29-41

The many faces of regulatory T cells

Author keywords

Autoimmunity; Regulatory T cell; Tumor immunity

Indexed keywords

CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; INTERLEUKIN 2; PEPTIDE DERIVATIVE; PROTEOME; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA; TUMOR VACCINE;

EID: 34347373935     PISSN: 02139626     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (1)

References (124)
  • 2
    • 16544364635 scopus 로고    scopus 로고
    • Immunology. Policing the immune system
    • Wickelgren I. Immunology. Policing the immune system. Science 2004;306:596-599.
    • (2004) Science , vol.306 , pp. 596-599
    • Wickelgren, I.1
  • 3
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003;3:253-257.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 4
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 6
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S. Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 2002;3:135-142.
    • (2002) Nat Immunol , vol.3 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3    Ishida, Y.4    Sakaguchi, S.5
  • 10
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell 1987;49:273-280.
    • (1987) Cell , vol.49 , pp. 273-280
    • Kappler, J.W.1    Roehm, N.2    Marrack, P.3
  • 11
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nat Rev Immunol 2002;2:389-400.
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 12
    • 0033558278 scopus 로고    scopus 로고
    • Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: Relationship to the quality of individual TCR signaling events
    • Itoh Y, Hemmer B, Martin R, Germain RN. Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: relationship to the quality of individual TCR signaling events. J Immunol 1999;162:2073-2080.
    • (1999) J Immunol , vol.162 , pp. 2073-2080
    • Itoh, Y.1    Hemmer, B.2    Martin, R.3    Germain, R.N.4
  • 13
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 14
    • 25844504653 scopus 로고    scopus 로고
    • Developmental regulation of Foxp3 expression during ontogeny
    • Fontenot JD, Dooley JL, Farr AG, Rudensky AY. Developmental regulation of Foxp3 expression during ontogeny. J Exp Med 2005;202:901-906.
    • (2005) J Exp Med , vol.202 , pp. 901-906
    • Fontenot, J.D.1    Dooley, J.L.2    Farr, A.G.3    Rudensky, A.Y.4
  • 16
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994;265:1237-1240.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 17
    • 0037018104 scopus 로고    scopus 로고
    • In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)-and Th2-inducing cytokines
    • Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, Savelkoul HF, de Waal-Malefyt R, et al. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)-and Th2-inducing cytokines. J Exp Med 2002;195:603-616.
    • (2002) J Exp Med , vol.195 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3    Richards, D.F.4    Crain, C.5    Savelkoul, H.F.6    de Waal-Malefyt, R.7
  • 18
    • 0034613767 scopus 로고    scopus 로고
    • Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • Jonuleit H, Schmitt E, Schuler G, Knop J, Enk AH. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 2000;192:1213-1222.
    • (2000) J Exp Med , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 20
    • 33747143361 scopus 로고    scopus 로고
    • From vanilla to 28 flavors: Multiple varieties of T regulatory cells
    • Shevach EM. From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 2006;25:195-201.
    • (2006) Immunity , vol.25 , pp. 195-201
    • Shevach, E.M.1
  • 22
    • 0347994958 scopus 로고    scopus 로고
    • B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions
    • Taylor PA, Lees CJ, Fournier S, Allison JP, Sharpe AH, Blazar BR. B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions. J Immunol 2004;172:34-39.
    • (2004) J Immunol , vol.172 , pp. 34-39
    • Taylor, P.A.1    Lees, C.J.2    Fournier, S.3    Allison, J.P.4    Sharpe, A.H.5    Blazar, B.R.6
  • 24
    • 3142708571 scopus 로고    scopus 로고
    • Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
    • Paust S, Lu L, McCarty N, Cantor H. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc Natl Acad Sci U S A 2004;101:10398-10403.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10398-10403
    • Paust, S.1    Lu, L.2    McCarty, N.3    Cantor, H.4
  • 25
    • 4544241811 scopus 로고    scopus 로고
    • Tolerance, not immunity, crucially depends on IL-2
    • Malek TR, Bayer AL. Tolerance, not immunity, crucially depends on IL-2. Nat Rev Immunol 2004;4:665-674.
    • (2004) Nat Rev Immunol , vol.4 , pp. 665-674
    • Malek, T.R.1    Bayer, A.L.2
  • 27
    • 0036669298 scopus 로고    scopus 로고
    • CD4 regulatory T cells prevent lethal autoimmunity in IL-2R,-deficient mice. Implications for the nonredundant function of IL-2
    • Malek TR, Yu A, Vincek V, Scibelli P, Kong L. CD4 regulatory T cells prevent lethal autoimmunity in IL-2R,-deficient mice. Implications for the nonredundant function of IL-2. Immunity 2002;17:167-178.
    • (2002) Immunity , vol.17 , pp. 167-178
    • Malek, T.R.1    Yu, A.2    Vincek, V.3    Scibelli, P.4    Kong, L.5
  • 29
    • 33644784733 scopus 로고    scopus 로고
    • + CD25(hi) Foxp3+ regulatory T cells in cancer patients
    • + CD25(hi) Foxp3+ regulatory T cells in cancer patients. Blood 2006;107:2409-2414.
    • (2006) Blood , vol.107 , pp. 2409-2414
    • Ahmadzadeh, M.1    Rosenberg, S.A.2
  • 30
    • 14744268262 scopus 로고    scopus 로고
    • + T regulatory cells, immunotherapy of cancer, and interleukin-2
    • + T regulatory cells, immunotherapy of cancer, and interleukin-2. J Immunother 2005;28:120-128.
    • (2005) J Immunother , vol.28 , pp. 120-128
    • Antony, P.A.1    Restifo, N.P.2
  • 31
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998;188:287-296.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 32
    • 0035801335 scopus 로고    scopus 로고
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med 2001;194:629-644.
    • (2001) J Exp Med , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 33
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-β
    • Letterio JJ, Roberts AB. Regulation of immune responses by TGF-β. Annu Rev Immunol 1998;16:137-161.
    • (1998) Annu Rev Immunol , vol.16 , pp. 137-161
    • Letterio, J.J.1    Roberts, A.B.2
  • 34
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 1999;190:995-1004.
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 37
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immunol 2005;6:338-344.
    • (2005) Nat Immunol , vol.6 , pp. 338-344
    • von Boehmer, H.1
  • 38
    • 0037099733 scopus 로고    scopus 로고
    • + regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
    • + regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells. J Exp Med 2002;196:247-253.
    • (2002) J Exp Med , vol.196 , pp. 247-253
    • Dieckmann, D.1    Bruett, C.H.2    Ploettner, H.3    Lutz, M.B.4    Schuler, G.5
  • 40
    • 0033985780 scopus 로고    scopus 로고
    • + immunoregulatory T cells is antigen nonspecific
    • + immunoregulatory T cells is antigen nonspecific. J Immunol 2000;164:183-190.
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 41
    • 5644302161 scopus 로고    scopus 로고
    • Human T regulatory cells can use the perforin pathway to cause autologous target cell death
    • Grossman WJ, Verbsky JW, Barchet W, Colonna M, Atkinson JP, Ley TJ. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity 2004;21:589-601.
    • (2004) Immunity , vol.21 , pp. 589-601
    • Grossman, W.J.1    Verbsky, J.W.2    Barchet, W.3    Colonna, M.4    Atkinson, J.P.5    Ley, T.J.6
  • 44
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
    • Levings MK, Bacchetta R, Schulz U, Roncarolo MG. The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol 2002;129:263-276.
    • (2002) Int Arch Allergy Immunol , vol.129 , pp. 263-276
    • Levings, M.K.1    Bacchetta, R.2    Schulz, U.3    Roncarolo, M.G.4
  • 46
    • 1942471974 scopus 로고    scopus 로고
    • In vivo-mobilized kidney dendritic cells are functionally immature, subvert alloreactive T-cell responses, and prolong organ allograft survival
    • Coates FT, Duncan FJ, Colvin BL, Wang Z, Zahorchak AF, Shufesky WJ, Morelli AE, et al. In vivo-mobilized kidney dendritic cells are functionally immature, subvert alloreactive T-cell responses, and prolong organ allograft survival. Transplantation 2004;77:1080-1089.
    • (2004) Transplantation , vol.77 , pp. 1080-1089
    • Coates, F.T.1    Duncan, F.J.2    Colvin, B.L.3    Wang, Z.4    Zahorchak, A.F.5    Shufesky, W.J.6    Morelli, A.E.7
  • 47
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: The tolerogenic function of immature dendritic cells
    • Mahnke K, Schmitt E, Bonifaz L, Enk AH, Jonuleit H. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 2002;80:477-483.
    • (2002) Immunol Cell Biol , vol.80 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3    Enk, A.H.4    Jonuleit, H.5
  • 50
    • 0034077559 scopus 로고    scopus 로고
    • + regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
    • + regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur J Immunol 2000;30:1538-1543.
    • (2000) Eur J Immunol , vol.30 , pp. 1538-1543
    • Cederbom, L.1    Hall, H.2    Ivars, F.3
  • 54
    • 18644366689 scopus 로고    scopus 로고
    • License to heal: Bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC
    • Vlad G, Cortesini R, Suciu-Foca N. License to heal: bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC. J Immunol 2005;174:5907-5914.
    • (2005) J Immunol , vol.174 , pp. 5907-5914
    • Vlad, G.1    Cortesini, R.2    Suciu-Foca, N.3
  • 57
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow ME, Jeffery EW, Hjerrild KA, Paeper B, Clark LB, Yasayko SA, Wilkinson JE, et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 2001;27:68-73.
    • (2001) Nat Genet , vol.27 , pp. 68-73
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3    Paeper, B.4    Clark, L.B.5    Yasayko, S.A.6    Wilkinson, J.E.7
  • 62
    • 16844365788 scopus 로고    scopus 로고
    • + regulatory T cells in immunological tolerance to self and non-self
    • + regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005;6:345-352.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 64
    • 33746189406 scopus 로고    scopus 로고
    • Foxp3 and NFAT: Partners in tolerance
    • Rudensky AY, Gavin M, Zheng Y. Foxp3 and NFAT: partners in tolerance. Cell 2006;126:253-256.
    • (2006) Cell , vol.126 , pp. 253-256
    • Rudensky, A.Y.1    Gavin, M.2    Zheng, Y.3
  • 66
    • 33644800026 scopus 로고    scopus 로고
    • Stroud JC, Wu Y, Bates DL, Han A, Nowick K, Paabo S, Tong H, et al. Structure of the forkhead domain of FOXP2 bound to DNA. Structure 2006;14.159-166.
    • Stroud JC, Wu Y, Bates DL, Han A, Nowick K, Paabo S, Tong H, et al. Structure of the forkhead domain of FOXP2 bound to DNA. Structure 2006;14.159-166.
  • 67
    • 26844577358 scopus 로고    scopus 로고
    • The many sounds of T lymphocyte silence
    • Melero I, Arina A, Chen L. The many sounds of T lymphocyte silence. Immunol Res 2005;33:135-147.
    • (2005) Immunol Res , vol.33 , pp. 135-147
    • Melero, I.1    Arina, A.2    Chen, L.3
  • 68
    • 0017076014 scopus 로고
    • Spontaneous development of autoimmune thyroiditis in neonatally thymectomized mice
    • Kojima A, Tanaka-Kojima Y, Sakakura T, Nishizuka Y. Spontaneous development of autoimmune thyroiditis in neonatally thymectomized mice. Lab Invest 1976;34:550-557.
    • (1976) Lab Invest , vol.34 , pp. 550-557
    • Kojima, A.1    Tanaka-Kojima, Y.2    Sakakura, T.3    Nishizuka, Y.4
  • 69
    • 0016435342 scopus 로고
    • Susceptibility of inbred rat strains to experimental thyroiditis: Quantitation of thyroglobulin-binding cells and assessment of T-cell function in susceptible and non-susceptible strains
    • Penhale WJ, Farmer A, Urbaniak SJ, Irvine WJ. Susceptibility of inbred rat strains to experimental thyroiditis: quantitation of thyroglobulin-binding cells and assessment of T-cell function in susceptible and non-susceptible strains. Clin Exp Immunol 1975;19:179-191.
    • (1975) Clin Exp Immunol , vol.19 , pp. 179-191
    • Penhale, W.J.1    Farmer, A.2    Urbaniak, S.J.3    Irvine, W.J.4
  • 70
    • 33646168597 scopus 로고    scopus 로고
    • Foxp3: Of mice and men
    • Ziegler SF. Foxp3: of mice and men. Annu Rev Immunol 2006;24:209-226.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 71
    • 0037152162 scopus 로고    scopus 로고
    • Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
    • Scheinecker C, McHugh R, Shevach EM, Germain RN. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J Exp Med 2002;196:1079-1090.
    • (2002) J Exp Med , vol.196 , pp. 1079-1090
    • Scheinecker, C.1    McHugh, R.2    Shevach, E.M.3    Germain, R.N.4
  • 73
    • 15244344608 scopus 로고    scopus 로고
    • Robinson DS, Larche M, Durham SR. Tregs and allergic disease. J Clin Invest 2004;114:1389-1397.
    • Robinson DS, Larche M, Durham SR. Tregs and allergic disease. J Clin Invest 2004;114:1389-1397.
  • 74
    • 0021997185 scopus 로고
    • Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
    • Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J Exp Med 1985;161:72-87.
    • (1985) J Exp Med , vol.161 , pp. 72-87
    • Sakaguchi, S.1    Fukuma, K.2    Kuribayashi, K.3    Masuda, T.4
  • 76
    • 0028348192 scopus 로고
    • Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells
    • Sakaguchi N, Miyai K, Sakaguchi S. Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells. J Immunol 1994;152:2586-2595.
    • (1994) J Immunol , vol.152 , pp. 2586-2595
    • Sakaguchi, N.1    Miyai, K.2    Sakaguchi, S.3
  • 77
    • 0033730056 scopus 로고    scopus 로고
    • Animal models of autoimmunity and their relevance to human diseases
    • Sakaguchi S. Animal models of autoimmunity and their relevance to human diseases. Curr Opin Immunol 2000;12:684-690.
    • (2000) Curr Opin Immunol , vol.12 , pp. 684-690
    • Sakaguchi, S.1
  • 79
    • 0034439970 scopus 로고    scopus 로고
    • Autoimmunity and the immunotherapy of cancer: Targeting the "self" to destroy the "other". Crit
    • Overwijk WW, Restifo NP. Autoimmunity and the immunotherapy of cancer: targeting the "self" to destroy the "other". Crit Rev Immunol 2000;20:433-450.
    • (2000) Rev Immunol , vol.20 , pp. 433-450
    • Overwijk, W.W.1    Restifo, N.P.2
  • 80
    • 33645286546 scopus 로고    scopus 로고
    • T cells, tumour immunity and immunotherapy
    • Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 2006;6:295-307.
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Regulatory, Z.W.1
  • 81
    • 1242295282 scopus 로고    scopus 로고
    • + immunoregulatory T cells: Central players in the arena of peripheral tolerance
    • + immunoregulatory T cells: central players in the arena of peripheral tolerance. Semin Immunol 2004;16:81-88.
    • (2004) Semin Immunol , vol.16 , pp. 81-88
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 82
    • 2442484053 scopus 로고    scopus 로고
    • + regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • + regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004;22:531-562.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 83
    • 0035056017 scopus 로고    scopus 로고
    • CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
    • Chambers CA, Kuhns MS, Egen JG, Allison JP. CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy. Annu Rev Immunol 2001;19:565-594.
    • (2001) Annu Rev Immunol , vol.19 , pp. 565-594
    • Chambers, C.A.1    Kuhns, M.S.2    Egen, J.G.3    Allison, J.P.4
  • 84
    • 1842424807 scopus 로고    scopus 로고
    • + T cell activation and experimental autoimmune encephalomyelitis
    • + T cell activation and experimental autoimmune encephalomyelitis. J Immunol 2004;172:4686-4690.
    • (2004) J Immunol , vol.172 , pp. 4686-4690
    • Kohm, A.P.1    Williams, J.S.2    Miller, S.D.3
  • 85
    • 0033571105 scopus 로고    scopus 로고
    • + T cells: A common basis between tumor immunity and autoimmunity
    • + T cells: a common basis between tumor immunity and autoimmunity. J Immunol 1999;163:5211-5218.
    • (1999) J Immunol , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 88
    • 0037436119 scopus 로고    scopus 로고
    • + T cell-mediated suppression by dendritic cells
    • + T cell-mediated suppression by dendritic cells. Science 2003;299:1033-1036.
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 89
    • 2442655250 scopus 로고    scopus 로고
    • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance
    • Yang Y, Huang CT, Huang X, Pardoll DM. Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat Immunol 2004;5:508-515.
    • (2004) Nat Immunol , vol.5 , pp. 508-515
    • Yang, Y.1    Huang, C.T.2    Huang, X.3    Pardoll, D.M.4
  • 91
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka S, Tawara I, Shimizu J, Sakaguchi S, Fujita T, Nakayama E. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res 1999;59:3128-3133.
    • (1999) Cancer Res , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 94
    • 33846530214 scopus 로고    scopus 로고
    • + T Cell Homeostasis. J Immunol 2007;178:1251-1255.
    • + T Cell Homeostasis. J Immunol 2007;178:1251-1255.
  • 95
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, Evdemon-Hogan M, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 2004;10:942-949.
    • (2004) Nat Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3    Alvarez, X.4    Cheng, P.5    Mottram, P.6    Evdemon-Hogan, M.7
  • 97
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage UK, Moore TT, Joo HG, Tanaka Y, Herrmann V, Doherty G, Drebin JA, et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol 2002;169:2756-2761.
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.G.3    Tanaka, Y.4    Herrmann, V.5    Doherty, G.6    Drebin, J.A.7
  • 99
    • 0037217371 scopus 로고    scopus 로고
    • + suppressor lymphocytes in the circulation of patients immunized against melanoma antigens
    • + suppressor lymphocytes in the circulation of patients immunized against melanoma antigens. J Immunother 2003;26:85-93.
    • (2003) J Immunother , vol.26 , pp. 85-93
    • Javia, L.R.1    Rosenberg, S.A.2
  • 101
    • 1642331576 scopus 로고    scopus 로고
    • Immune regulation by self-reactive T cells is antigen specific
    • Tanchot C, Vasseur F, Pontoux C, Garcia C, Sarukhan A. Immune regulation by self-reactive T cells is antigen specific. J Immunol 2004;172:4285-4291.
    • (2004) J Immunol , vol.172 , pp. 4285-4291
    • Tanchot, C.1    Vasseur, F.2    Pontoux, C.3    Garcia, C.4    Sarukhan, A.5
  • 102
    • 3142737258 scopus 로고    scopus 로고
    • +CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
    • +CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol 2004;173:1444-1453.
    • (2004) J Immunol , vol.173 , pp. 1444-1453
    • Viguier, M.1    Lemaitre, F.2    Verola, O.3    Cho, M.S.4    Gorochov, G.5    Dubertret, L.6    Bachelez, H.7
  • 105
    • 1542309563 scopus 로고    scopus 로고
    • Immunoregulatory T cells in tumor immunity
    • Terabe M, Berzofsky JA. Immunoregulatory T cells in tumor immunity. Curr Opin Immunol 2004;16:157-162.
    • (2004) Curr Opin Immunol , vol.16 , pp. 157-162
    • Terabe, M.1    Berzofsky, J.A.2
  • 110
    • 33745323050 scopus 로고    scopus 로고
    • + regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B
    • + regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol 2006;177:739-747.
    • (2006) J Immunol , vol.177 , pp. 739-747
    • Xu, D.1    Fu, J.2    Jin, L.3    Zhang, H.4    Zhou, C.5    Zou, Z.6    Zhao, J.M.7
  • 111
    • 10744227590 scopus 로고    scopus 로고
    • + regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens
    • + regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J Virol 2004;78:2454-2459.
    • (2004) J Virol , vol.78 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 112
    • 3543098686 scopus 로고    scopus 로고
    • + HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
    • + HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med 2004;200:331-343.
    • (2004) J Exp Med , vol.200 , pp. 331-343
    • Kinter, A.L.1    Hennessey, M.2    Bell, A.3    Kern, S.4    Lin, Y.5    Daucher, M.6    Planta, M.7
  • 114
    • 33144476838 scopus 로고    scopus 로고
    • Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection
    • Estes JD, Li Q, Reynolds MR, Wietgrefe S, Duan L, Schacker T, Picker LJ, et al. Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. J Infect Dis 2006;193:703-712.
    • (2006) J Infect Dis , vol.193 , pp. 703-712
    • Estes, J.D.1    Li, Q.2    Reynolds, M.R.3    Wietgrefe, S.4    Duan, L.5    Schacker, T.6    Picker, L.J.7
  • 119
    • 0035554675 scopus 로고    scopus 로고
    • The risk of autoimmunity associated with tumor immunotherapy
    • Gilboa E. The risk of autoimmunity associated with tumor immunotherapy. Nat Immunol 2001;2:789-792.
    • (2001) Nat Immunol , vol.2 , pp. 789-792
    • Gilboa, E.1
  • 121
    • 33745945647 scopus 로고    scopus 로고
    • Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo
    • Warger T, Osterloh P, Rechtsteiner G, Fassbender M, Heib V, Schmid B, Schmitt E, et al. Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo. Blood 2006;108:544-550.
    • (2006) Blood , vol.108 , pp. 544-550
    • Warger, T.1    Osterloh, P.2    Rechtsteiner, G.3    Fassbender, M.4    Heib, V.5    Schmid, B.6    Schmitt, E.7
  • 122
  • 123
    • 4043102582 scopus 로고    scopus 로고
    • Regulatory cells and infectious agents: Detentes cordiale and contraire
    • Rouse BT, Suvas S. Regulatory cells and infectious agents: detentes cordiale and contraire. J Immunol 2004;173:2211-2215.
    • (2004) J Immunol , vol.173 , pp. 2211-2215
    • Rouse, B.T.1    Suvas, S.2


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