-
1
-
-
23444451611
-
Mood disorders in the medically ill: Scientific review and recommendations
-
Evans DL, Charney DS, Lewis L, et al. Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry 2005; 58: 175-89.
-
(2005)
Biol Psychiatry
, vol.58
, pp. 175-189
-
-
Evans, D.L.1
Charney, D.S.2
Lewis, L.3
-
3
-
-
0034158465
-
Searching high and low: A review of the genetics of bipolar disorder
-
Potash JB, DePaulo JR, Jr. Searching high and low: a review of the genetics of bipolar disorder. Bipolar Disord 2000; 2: 8-26.
-
(2000)
Bipolar Disord
, vol.2
, pp. 8-26
-
-
Potash, J.B.1
DePaulo Jr., J.R.2
-
4
-
-
0032803524
-
Genetics of bipolar disorder
-
Craddock N, Jones I. Genetics of bipolar disorder. J Med Genet 1999; 36: 585-94.
-
(1999)
J Med Genet
, vol.36
, pp. 585-594
-
-
Craddock, N.1
Jones, I.2
-
5
-
-
0033810465
-
Genetic epidemiology of major depression: Review and meta-analysis
-
Sullivan PF, Neale MC, Kendler KS. Genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry 2000; 157: 1552-62.
-
(2000)
Am J Psychiatry
, vol.157
, pp. 1552-1562
-
-
Sullivan, P.F.1
Neale, M.C.2
Kendler, K.S.3
-
6
-
-
0033639081
-
-
Fava M, Kendler KS. Major depressive disorder. Neuron 2000; 28: 335-41.
-
Fava M, Kendler KS. Major depressive disorder. Neuron 2000; 28: 335-41.
-
-
-
-
7
-
-
1542276351
-
-
Manji HK, Gottesman, II, Gould TD. Signal transduction and genes-to-behaviors pathways in psychiatric diseases. Sci STKE 2003; 2003: pe49.
-
Manji HK, Gottesman, II, Gould TD. Signal transduction and genes-to-behaviors pathways in psychiatric diseases. Sci STKE 2003; 2003: pe49.
-
-
-
-
8
-
-
0242322769
-
Epigenetics and bipolar disorder: New opportunities and challenges
-
Petronis A. Epigenetics and bipolar disorder: new opportunities and challenges. Am J Med Genet 2003; 123C: 65-75.
-
(2003)
Am J Med Genet
, vol.123 C
, pp. 65-75
-
-
Petronis, A.1
-
9
-
-
0037042065
-
-
Lenox RH, Gould TD, Manji HK. Endophcnotypes in bipolar disorder. Am J Med Genet 2002; 114: 391-406.
-
Lenox RH, Gould TD, Manji HK. Endophcnotypes in bipolar disorder. Am J Med Genet 2002; 114: 391-406.
-
-
-
-
10
-
-
0038823525
-
The endophenotype concept in psychiatry: Etymology and strategic intentions
-
Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003; 160: 636-45.
-
(2003)
Am J Psychiatry
, vol.160
, pp. 636-645
-
-
Gottesman, I.I.1
Gould, T.D.2
-
11
-
-
33644753148
-
Psychiatric endophenotypes and the development of valid animal models
-
Gould TD, Gottesman II. Psychiatric endophenotypes and the development of valid animal models. Genes Brain Behav 2006; 5(2): 113-9.
-
(2006)
Genes Brain Behav
, vol.5
, Issue.2
, pp. 113-119
-
-
Gould, T.D.1
Gottesman II2
-
12
-
-
0035719852
-
Lithium treatment at 52
-
Schou M. Lithium treatment at 52. J Affect Disord 2001; 67: 21-32.
-
(2001)
J Affect Disord
, vol.67
, pp. 21-32
-
-
Schou, M.1
-
13
-
-
10744220918
-
Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression
-
Tohen M, Vieta E, Calabrese J, et al. Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. Arch Gen Psychiatry 2003; 60: 1079-88.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 1079-1088
-
-
Tohen, M.1
Vieta, E.2
Calabrese, J.3
-
14
-
-
14544288719
-
Treatment options for bipolar depression
-
Bowden CL. Treatment options for bipolar depression. J Clin Psychiatry 2005; 66(Suppl 1): 3-6.
-
(2005)
J Clin Psychiatry
, vol.66
, Issue.SUPPL. 1
, pp. 3-6
-
-
Bowden, C.L.1
-
15
-
-
0028047366
-
Electroconvulsive therapy of acute manic episodes: A review of 50 years' experience
-
Mukherjee S, Sackeim HA, Schnur DB. Electroconvulsive therapy of acute manic episodes: a review of 50 years' experience. Am J Psychiatry 1994; 151: 169-76.
-
(1994)
Am J Psychiatry
, vol.151
, pp. 169-176
-
-
Mukherjee, S.1
Sackeim, H.A.2
Schnur, D.B.3
-
16
-
-
0037051872
-
Placebo response in studies of major depression: Variable, substantial, and growing
-
Walsh BT, Seidman SN, Sysko R, Gould M. Placebo response in studies of major depression: variable, substantial, and growing. JAMA 2002; 287: 1840-7.
-
(2002)
JAMA
, vol.287
, pp. 1840-1847
-
-
Walsh, B.T.1
Seidman, S.N.2
Sysko, R.3
Gould, M.4
-
17
-
-
4243196940
-
Emerging experimental therapeutics for bipolar disorder: Insights from the molecular and cellular actions of current mood stabilizers
-
Gould TD, Quiroz JA, Singh J, Zarate CA, Manji HK. Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Mol Psychiatry 2004; 9: 734-55.
-
(2004)
Mol Psychiatry
, vol.9
, pp. 734-755
-
-
Gould, T.D.1
Quiroz, J.A.2
Singh, J.3
Zarate, C.A.4
Manji, H.K.5
-
18
-
-
4243165658
-
Emerging experimental therapeutics for bipolar disorder: Clues from the molecular pathophysiology
-
Quiroz JA, Singh J, Gould TD, et al. Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology. Mol Psychiatry 2004; 9: 756-76.
-
(2004)
Mol Psychiatry
, vol.9
, pp. 756-776
-
-
Quiroz, J.A.1
Singh, J.2
Gould, T.D.3
-
19
-
-
0035936798
-
Molecular and cellular mechanisms of cardiac arrhythmias
-
Keating MT, Sanguinetti MC. Molecular and cellular mechanisms of cardiac arrhythmias. Cell 2001; 104: 569-80.
-
(2001)
Cell
, vol.104
, pp. 569-580
-
-
Keating, M.T.1
Sanguinetti, M.C.2
-
21
-
-
0034566357
-
Post-receptor signaling pathways in die pathophysiology and treatment of mood disorders
-
Manji HK, Chen G. Post-receptor signaling pathways in die pathophysiology and treatment of mood disorders. Curr Psychiatry Rep 2000; 2: 479-89.
-
(2000)
Curr Psychiatry Rep
, vol.2
, pp. 479-489
-
-
Manji, H.K.1
Chen, G.2
-
23
-
-
0038135192
-
The genes and brains of mice and men
-
Tecott LH. The genes and brains of mice and men. Am J Psychiatry 2003; 160: 646-56.
-
(2003)
Am J Psychiatry
, vol.160
, pp. 646-656
-
-
Tecott, L.H.1
-
24
-
-
16044362074
-
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
-
Joutel A, Corpechot C, Ducros A, et al. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature 1996; 383: 707-10.
-
(1996)
Nature
, vol.383
, pp. 707-710
-
-
Joutel, A.1
Corpechot, C.2
Ducros, A.3
-
25
-
-
17344362307
-
Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy
-
Minassian BA, Lee JR, Herbrick JA, et al. Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy. Nat Genet 1998; 20: 171-4.
-
(1998)
Nat Genet
, vol.20
, pp. 171-174
-
-
Minassian, B.A.1
Lee, J.R.2
Herbrick, J.A.3
-
26
-
-
0031710557
-
PAK3 mutation in nonsyndromic X-linked mental retardation
-
Allen KM, Gleeson JG, Bagrodia S, et al. PAK3 mutation in nonsyndromic X-linked mental retardation. Nat Genet 1998; 20: 25-30.
-
(1998)
Nat Genet
, vol.20
, pp. 25-30
-
-
Allen, K.M.1
Gleeson, J.G.2
Bagrodia, S.3
-
28
-
-
0035283058
-
Human morbid genetics revisited: Relevance of epigenetics
-
Petronis A. Human morbid genetics revisited: relevance of epigenetics. Trends Genet 2001; 17: 142-6.
-
(2001)
Trends Genet
, vol.17
, pp. 142-146
-
-
Petronis, A.1
-
29
-
-
0141560434
-
Alternative splicing in the nervous system: An emerging source of diversity and regulation
-
Lee CJ, Irizarry K. Alternative splicing in the nervous system: an emerging source of diversity and regulation. Biol Psychiatry 2003; 54: 771-6.
-
(2003)
Biol Psychiatry
, vol.54
, pp. 771-776
-
-
Lee, C.J.1
Irizarry, K.2
-
31
-
-
0018774833
-
Di-n-propylacetale and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase
-
van der Laan JW, de Boer T, Bruinvels J. Di-n-propylacetale and GABA degradation. Preferential inhibition of succinic semialdehyde dehydrogenase and indirect inhibition of GABA-transaminase. J Neurochem 1979; 32:1769-80.
-
(1979)
J Neurochem
, vol.32
, pp. 1769-1780
-
-
van der Laan, J.W.1
de Boer, T.2
Bruinvels, J.3
-
32
-
-
0017087116
-
-
P
-
Anlezark GM, Horton RW, Meldrum, BS, Sawaya MC, Stephenson JD. Proceedings: gamma-Aminobutyric acid metabolism and the anticonvulsant action of ethanolamine-o-sulphate and di-n-propylacetate. Br J Pharmacol 1976; 56: 383P-384P.
-
(1976)
Proceedings: Gamma-Aminobutyric acid metabolism and the anticonvulsant action of ethanolamine-o-sulphate and di-n-propylacetate. Br J Pharmacol
, vol.56
-
-
Anlezark, G.M.1
Horton, R.W.2
Meldrum, B.S.3
Sawaya, M.C.4
Stephenson, J.D.5
-
33
-
-
0016730142
-
Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA
-
Sawaya MC, Horton RW, Meldrum BS. Effects of anticonvulsant drugs on the cerebral enzymes metabolizing GABA. Epilepsia 1975; 16: 649-55.
-
(1975)
Epilepsia
, vol.16
, pp. 649-655
-
-
Sawaya, M.C.1
Horton, R.W.2
Meldrum, B.S.3
-
34
-
-
0018084690
-
Effects of the anticonvulsant sodium valproate on gamma-aminobutyrate and aldehyde metabolism in ox brain
-
Whittle SR, Turner AJ. Effects of the anticonvulsant sodium valproate on gamma-aminobutyrate and aldehyde metabolism in ox brain. J Neurochem 1978; 31: 1453-9.
-
(1978)
J Neurochem
, vol.31
, pp. 1453-1459
-
-
Whittle, S.R.1
Turner, A.J.2
-
35
-
-
0034257051
-
Mechanisms of action of valproate: A commentatory
-
Johannessen CU. Mechanisms of action of valproate: a commentatory. Neurochem Int 2000; 37: 103-10.
-
(2000)
Neurochem Int
, vol.37
, pp. 103-110
-
-
Johannessen, C.U.1
-
36
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
Gottlicher M, Minucci S, Zhu P, et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. Embo J 2001; 20: 6969-78.
-
(2001)
Embo J
, vol.20
, pp. 6969-6978
-
-
Gottlicher, M.1
Minucci, S.2
Zhu, P.3
-
37
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
-
Phiel CJ, Zhang F, Huang EY, et al. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 2001; 276: 36734-41.
-
(2001)
J Biol Chem
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
Zhang, F.2
Huang, E.Y.3
-
39
-
-
0036810240
-
Lithium and valproic acid: Parallels and contrasts in diverse signaling contexts
-
Gurvich N, Klein PS. Lithium and valproic acid: parallels and contrasts in diverse signaling contexts. Pharmacol Ther 2002; 96: 45-66.
-
(2002)
Pharmacol Ther
, vol.96
, pp. 45-66
-
-
Gurvich, N.1
Klein, P.S.2
-
40
-
-
0030032338
-
Initiation and adaptation: A paradigm for understanding psychotropic drug action
-
Hyman SE, Nestler EJ. Initiation and adaptation: a paradigm for understanding psychotropic drug action. Am J Psychiatry 1996; 153: 151-62.
-
(1996)
Am J Psychiatry
, vol.153
, pp. 151-162
-
-
Hyman, S.E.1
Nestler, E.J.2
-
41
-
-
0037688084
-
Finding the intracellular signaling pathways affected by mood disorder treatments
-
Coyle JT, Duman RS. Finding the intracellular signaling pathways affected by mood disorder treatments. Neuron 2003; 38: 157-160.
-
(2003)
Neuron
, vol.38
, pp. 157-160
-
-
Coyle, J.T.1
Duman, R.S.2
-
42
-
-
0036705074
-
Signaling networks in the pathophysiology and treatment of mood disorders
-
Gould TD, Manji HK. Signaling networks in the pathophysiology and treatment of mood disorders. J Psychosom Res 2002; 53: 687-697.
-
(2002)
J Psychosom Res
, vol.53
, pp. 687-697
-
-
Gould, T.D.1
Manji, H.K.2
-
43
-
-
0030455770
-
Regulation of signal transduction pathways by mood-stabilizing agents: Implications for the delayed onset of therapeutic efficacy
-
discussion 47-8
-
Manji HK, Chen G, Hsiao JK, et al. Regulation of signal transduction pathways by mood-stabilizing agents: implications for the delayed onset of therapeutic efficacy. J Clin Psychiatry 1996; 57: 34-46; discussion 47-8.
-
(1996)
J Clin Psychiatry
, vol.57
, pp. 34-46
-
-
Manji, H.K.1
Chen, G.2
Hsiao, J.K.3
-
44
-
-
0031807854
-
Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis
-
Plotsky PM, Owens MJ, Nemeroff CH. Psychoneuroendocrinology of depression. Hypothalamic-pituitary-adrenal axis. Psychiatr Clin North Am 1998; 21: 293-307.
-
(1998)
Psychiatr Clin North Am
, vol.21
, pp. 293-307
-
-
Plotsky, P.M.1
Owens, M.J.2
Nemeroff, C.H.3
-
45
-
-
0038147541
-
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression
-
Manji HK, Quiroz JA, Sporn J, et al. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biol Psychiatry 2003; 53: 707-42.
-
(2003)
Biol Psychiatry
, vol.53
, pp. 707-742
-
-
Manji, H.K.1
Quiroz, J.A.2
Sporn, J.3
-
46
-
-
0036089270
-
New directions in the development of antidepressants: The interface of neurobiology and psychiatry
-
Nemeroff CB. New directions in the development of antidepressants: the interface of neurobiology and psychiatry. Hum Psychopharmacol 2002; 17(Suppl 1): S13-6.
-
(2002)
Hum Psychopharmacol
, vol.17
, Issue.SUPPL. 1
-
-
Nemeroff, C.B.1
-
47
-
-
0141517336
-
Neuroanatomical circuits modulating fear and anxiety behaviors
-
Charney DS. Neuroanatomical circuits modulating fear and anxiety behaviors. Acta Psychiatr Scand Suppl 2003; 417: 38-50.
-
(2003)
Acta Psychiatr Scand Suppl
, vol.417
, pp. 38-50
-
-
Charney, D.S.1
-
48
-
-
0029584365
-
Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain
-
Mamounas LA, Blue ME, Siuciak JA, Altar CA. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. J Neurosci 1995; 15: 7929-39.
-
(1995)
J Neurosci
, vol.15
, pp. 7929-7939
-
-
Mamounas, L.A.1
Blue, M.E.2
Siuciak, J.A.3
Altar, C.A.4
-
49
-
-
0033579301
-
Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons
-
Riccio A, Ahn S, Davenport CM, Blendy JA, Ginty DD. Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science 1999; 286: 2358-61.
-
(1999)
Science
, vol.286
, pp. 2358-2361
-
-
Riccio, A.1
Ahn, S.2
Davenport, C.M.3
Blendy, J.A.4
Ginty, D.D.5
-
50
-
-
0035369840
-
Trk receptors: Mediators of neurotrophin action
-
Patapoutian A, Reichardt LF. Trk receptors: mediators of neurotrophin action. Curr Opin Neurobiol 2001; 11: 272-80.
-
(2001)
Curr Opin Neurobiol
, vol.11
, pp. 272-280
-
-
Patapoutian, A.1
Reichardt, L.F.2
-
51
-
-
0034859101
-
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
-
Grimes CA, Jope RS. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol 2001; 65: 391-426.
-
(2001)
Prog Neurobiol
, vol.65
, pp. 391-426
-
-
Grimes, C.A.1
Jope, R.S.2
-
54
-
-
0033232499
-
Neural plasticity to stress and antidepressant treatment
-
Duman RS, Malberg J, Thome J. Neural plasticity to stress and antidepressant treatment. Biol Psychiatry 1999; 46: 1181-91.
-
(1999)
Biol Psychiatry
, vol.46
, pp. 1181-1191
-
-
Duman, R.S.1
Malberg, J.2
Thome, J.3
-
56
-
-
0037092425
-
Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
-
Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 2002; 22: 3251-61.
-
(2002)
J Neurosci
, vol.22
, pp. 3251-3261
-
-
Shirayama, Y.1
Chen, A.C.2
Nakagawa, S.3
Russell, D.S.4
Duman, R.S.5
-
57
-
-
0035338399
-
Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect
-
Chen AC, Shirayama Y, Shin KH, Neve RL, Duman RS. Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect. Biol Psychiatry 2001; 49: 753-62.
-
(2001)
Biol Psychiatry
, vol.49
, pp. 753-762
-
-
Chen, A.C.1
Shirayama, Y.2
Shin, K.H.3
Neve, R.L.4
Duman, R.S.5
-
58
-
-
3242666768
-
Essential role of brain-derived neurotrophic factor in adult hippocampal function
-
Monteggia LM, Barrot M, Powell CM, et al. Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proc Natl Acad Sci USA 2004; 101: 10827-32.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10827-10832
-
-
Monteggia, L.M.1
Barrot, M.2
Powell, C.M.3
-
59
-
-
0034671366
-
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
-
Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 2000; 20: 9104-10.
-
(2000)
J Neurosci
, vol.20
, pp. 9104-9110
-
-
Malberg, J.E.1
Eisch, A.J.2
Nestler, E.J.3
Duman, R.S.4
-
60
-
-
0042528720
-
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
-
Santarelli L, Saxe M, Gross C, et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003; 301: 805-9.
-
(2003)
Science
, vol.301
, pp. 805-809
-
-
Santarelli, L.1
Saxe, M.2
Gross, C.3
-
61
-
-
3242797374
-
Neurogenesis and depression: Etiology of epiphenomenon?
-
Henn FA, Vollmayr B. Neurogenesis and depression: etiology of epiphenomenon? Biol Psychiatry 2004; 56: 146-50.
-
(2004)
Biol Psychiatry
, vol.56
, pp. 146-150
-
-
Henn, F.A.1
Vollmayr, B.2
-
62
-
-
3242745166
-
Depression: A case of neuronal life and death?
-
Duman RS. Depression: a case of neuronal life and death? Biol Psychiatry 2004; 56: 140-5.
-
(2004)
Biol Psychiatry
, vol.56
, pp. 140-145
-
-
Duman, R.S.1
-
63
-
-
3242808933
-
Is impaired neurogenesis relevant to the affective symptoms of depression?
-
Sapolsky RM. Is impaired neurogenesis relevant to the affective symptoms of depression? Biol Psychiatry 2004; 56: 137-9.
-
(2004)
Biol Psychiatry
, vol.56
, pp. 137-139
-
-
Sapolsky, R.M.1
-
64
-
-
0242391945
-
Reduced cell proliferation in the dentate gyrus is not correlated with the development of learned helplessness
-
Vollmayr B, Simonis C, Weber S, Gass P, Henn F. Reduced cell proliferation in the dentate gyrus is not correlated with the development of learned helplessness. Biol Psychiatry 2003; 54: 1035-40.
-
(2003)
Biol Psychiatry
, vol.54
, pp. 1035-1040
-
-
Vollmayr, B.1
Simonis, C.2
Weber, S.3
Gass, P.4
Henn, F.5
-
65
-
-
0035943699
-
The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
-
Yuan PX, Huang LD, Jiang YM, et al. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J Biol Chem 2001; 276: 31674-83.
-
(2001)
J Biol Chem
, vol.276
, pp. 31674-31683
-
-
Yuan, P.X.1
Huang, L.D.2
Jiang, Y.M.3
-
66
-
-
0043240266
-
The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
-
Einat H, Yuan P, Gould TD, et al. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J Neurosci 2003; 23: 7311-6.
-
(2003)
J Neurosci
, vol.23
, pp. 7311-7316
-
-
Einat, H.1
Yuan, P.2
Gould, T.D.3
-
67
-
-
3242788185
-
Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
-
Hao Y, Creson T, Zhang L, et al. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. J Neurosci 2004; 24: 6590-9.
-
(2004)
J Neurosci
, vol.24
, pp. 6590-6599
-
-
Hao, Y.1
Creson, T.2
Zhang, L.3
-
68
-
-
0032956630
-
The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bc1-2 in the CNS
-
Chen G, Zeng WZ, Yuan PX, et al. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bc1-2 in the CNS. J Neurochem 1999; 72: 879-82.
-
(1999)
J Neurochem
, vol.72
, pp. 879-882
-
-
Chen, G.1
Zeng, W.Z.2
Yuan, P.X.3
-
69
-
-
0033817849
-
Enhancement of hippocampal neurogenesis by lithium
-
Chen G, Rajkowska G, Du F, Seraji-Bozorgzad N, Manji HK. Enhancement of hippocampal neurogenesis by lithium. J Neurochem 2000; 75: 1729-34.
-
(2000)
J Neurochem
, vol.75
, pp. 1729-1734
-
-
Chen, G.1
Rajkowska, G.2
Du, F.3
Seraji-Bozorgzad, N.4
Manji, H.K.5
-
70
-
-
0033525538
-
Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuro-protection against excitotoxicity
-
Chen RW, Chuang DM. Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuro-protection against excitotoxicity. J Biol Chem 1999; 274: 6039-42.
-
(1999)
J Biol Chem
, vol.274
, pp. 6039-6042
-
-
Chen, R.W.1
Chuang, D.M.2
-
71
-
-
1842419074
-
Lithium selectively increases neuronal differentiation of hippocampal neural progenitor cells both in vitro and in vivo
-
Kim JS, Chang MY, Yu IT, et al. Lithium selectively increases neuronal differentiation of hippocampal neural progenitor cells both in vitro and in vivo. J Neurochem 2004; 89: 324-36.
-
(2004)
J Neurochem
, vol.89
, pp. 324-336
-
-
Kim, J.S.1
Chang, M.Y.2
Yu, I.T.3
-
72
-
-
0038587636
-
Lithium enhances long-term potentiation independently of hippocampal neurogenesis in the rat dentate gyrus
-
Son H, Yu IT, Hwang SJ, et al. Lithium enhances long-term potentiation independently of hippocampal neurogenesis in the rat dentate gyrus. J Neurochem 2003; 85: 872-81.
-
(2003)
J Neurochem
, vol.85
, pp. 872-881
-
-
Son, H.1
Yu, I.T.2
Hwang, S.J.3
-
73
-
-
0036116367
-
Neuroprotective effects of lithium in cultured cells and animal models of diseases
-
Chuang DM, Chen R, Chalecka-Franaszek E, et al. Neuroprotective effects of lithium in cultured cells and animal models of diseases. Bipolar Disorders 2002; 4: 129-16.
-
(2002)
Bipolar Disorders
, vol.4
, pp. 129-116
-
-
Chuang, D.M.1
Chen, R.2
Chalecka-Franaszek, E.3
-
74
-
-
0032827466
-
Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?
-
Manji HK, Moore GJ, Chen G. Lithium at 50: have the neuroprotective effects of this unique cation been overlooked? Biol Psychiatry 1999; 46: 929-40.
-
(1999)
Biol Psychiatry
, vol.46
, pp. 929-940
-
-
Manji, H.K.1
Moore, G.J.2
Chen, G.3
-
77
-
-
0034667299
-
Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: Implications for the pathophysiology and treatment of manic-depressive illness
-
Manji HK, Moore GJ, Chen G. Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness. Biol Psychiatry 2000; 48: 740-54.
-
(2000)
Biol Psychiatry
, vol.48
, pp. 740-754
-
-
Manji, H.K.1
Moore, G.J.2
Chen, G.3
-
78
-
-
0036328597
-
Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: Involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation
-
Hashimoto R, Hough C, Nakazawa T, Yamamoto T, Chuang DM. Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation. J Neurochem 2002; 80: 589-97.
-
(2002)
J Neurochem
, vol.80
, pp. 589-597
-
-
Hashimoto, R.1
Hough, C.2
Nakazawa, T.3
Yamamoto, T.4
Chuang, D.M.5
-
79
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein PS, Melton DA. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA 1996; 93: 8455-9.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
80
-
-
0036788036
-
The wnt signaling pathway in bipolar disorder
-
Gould TD, Manji HK. The wnt signaling pathway in bipolar disorder. Neuroscientist 2002; 8: 497-511.
-
(2002)
Neuroscientist
, vol.8
, pp. 497-511
-
-
Gould, T.D.1
Manji, H.K.2
-
81
-
-
20544437694
-
Glycogen synthase kinase-3: A putative molecular target for lithium mimetic drugs
-
Gould TD, Manji HK, Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs. Neuropsychopharmacology 2005; 30: 1223-37.
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 1223-1237
-
-
Gould, T.D.1
Manji, H.K.2
-
82
-
-
1842420631
-
Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus
-
Kaidanovich-Beilin O, Milman A, Weizman A, Pick CG, Eldar-Finkelman H. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus. Biol Psychiatry 2004; 55: 781-4.
-
(2004)
Biol Psychiatry
, vol.55
, pp. 781-784
-
-
Kaidanovich-Beilin, O.1
Milman, A.2
Weizman, A.3
Pick, C.G.4
Eldar-Finkelman, H.5
-
83
-
-
10644255687
-
AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
-
Gould TD, Einat H, Bhat R, Manji HK. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int J Neuropsychopharmacol 2004; 7: 1-4.
-
(2004)
Int J Neuropsychopharmacol
, vol.7
, pp. 1-4
-
-
Gould, T.D.1
Einat, H.2
Bhat, R.3
Manji, H.K.4
-
84
-
-
3342955475
-
Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium
-
O'Brien WT, Harper AD, Jove F, et al. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J Neurosci 2004; 24: 6791-8.
-
(2004)
J Neurosci
, vol.24
, pp. 6791-6798
-
-
O'Brien, W.T.1
Harper, A.D.2
Jove, F.3
-
85
-
-
3242761438
-
In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain
-
Li X, Zhu W, Roh MS, et al. In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain. Neuropsycho-pharmacology 2004; 29: 1426-31.
-
(2004)
Neuropsycho-pharmacology
, vol.29
, pp. 1426-1431
-
-
Li, X.1
Zhu, W.2
Roh, M.S.3
-
86
-
-
1842787936
-
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
-
Beaulieu JM, Sotnikova TD, Yao WD, et al. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc Natl Acad Sci USA 2004; 101: 5099-104.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5099-5104
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Yao, W.D.3
-
87
-
-
0842325787
-
Histone deacetylase is a target of valproic acid-mediated cellular differentiation
-
Gurvich N, Tsygankova OM, Meinkoth JL, Klein PS. Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Res 2004; 64: 1079-86.
-
(2004)
Cancer Res
, vol.64
, pp. 1079-1086
-
-
Gurvich, N.1
Tsygankova, O.M.2
Meinkoth, J.L.3
Klein, P.S.4
-
88
-
-
0037168650
-
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability
-
Tremolizzo L, Carboni G, Ruzicka WB, et al. An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proc Natl Acad Sci USA 2002; 99: 17095-100.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 17095-17100
-
-
Tremolizzo, L.1
Carboni, G.2
Ruzicka, W.B.3
-
89
-
-
0038380334
-
Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus
-
Yildirim E, Zhang Z, Uz T, et al. Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus. Neurosci Lett 2003; 345: 141-3.
-
(2003)
Neurosci Lett
, vol.345
, pp. 141-143
-
-
Yildirim, E.1
Zhang, Z.2
Uz, T.3
-
90
-
-
0038066627
-
Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: A role of histone deacetylase inhibition
-
Jeong MR, Hashimoto R, Senatorov VV, et al. Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition. FEBS Lett 2003; 542: 74-8.
-
(2003)
FEBS Lett
, vol.542
, pp. 74-78
-
-
Jeong, M.R.1
Hashimoto, R.2
Senatorov, V.V.3
-
91
-
-
19944431703
-
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease
-
Gardian G, Browne SE, Choi DK, et al. Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease. J Biol Chem 2005; 280: 556-63.
-
(2005)
J Biol Chem
, vol.280
, pp. 556-563
-
-
Gardian, G.1
Browne, S.E.2
Choi, D.K.3
-
92
-
-
0142157600
-
Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice
-
Ferrante RJ, Kubilus JK, Lee J, et al. Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. J Neurosci 2003; 23: 9418-27.
-
(2003)
J Neurosci
, vol.23
, pp. 9418-9427
-
-
Ferrante, R.J.1
Kubilus, J.K.2
Lee, J.3
-
93
-
-
3042651448
-
Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: Potential roles of histone deacetylase inhibition and beat shock protein induction
-
Ren M, Leng Y, Jeong M, Leeds PR, Chuang DM. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and beat shock protein induction. J Neurochem 2004; 89: 1358-67.
-
(2004)
J Neurochem
, vol.89
, pp. 1358-1367
-
-
Ren, M.1
Leng, Y.2
Jeong, M.3
Leeds, P.R.4
Chuang, D.M.5
-
94
-
-
0034619037
-
Lithium-induced increase in human brain grey matter
-
Moore GJ, Bebchuk JM, Wilds IB, et al. Lithium-induced increase in human brain grey matter. Lancet 2000; 356: 1241-2.
-
(2000)
Lancet
, vol.356
, pp. 1241-1242
-
-
Moore, G.J.1
Bebchuk, J.M.2
Wilds, I.B.3
-
95
-
-
18744435263
-
Lithium increases N-acetyl-aspartate in the human brain: In vivo evidence in support of bcl-2′s neurotrophic effects?
-
Moore GJ, Bebchuk JM, Hasanat K, et al. Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2′s neurotrophic effects? Biol Psychiatry 2000; 48: 1-8.
-
(2000)
Biol Psychiatry
, vol.48
, pp. 1-8
-
-
Moore, G.J.1
Bebchuk, J.M.2
Hasanat, K.3
-
96
-
-
20544452720
-
Neuroimaging methodologies: Utilizing radiotracers or nuclear magnetic resonance
-
Charney DS, Nester EJ, eds, 2 ed. New York, Oxford University Press
-
Seibyl JP, Scanley BE, Krystal JH, Innis RB. Neuroimaging methodologies: utilizing radiotracers or nuclear magnetic resonance. In: Charney DS, Nester EJ, eds, Neurobiology of Mental Illness 2 ed. New York, Oxford University Press 2004; 190-209.
-
(2004)
Neurobiology of Mental Illness
, pp. 190-209
-
-
Seibyl, J.P.1
Scanley, B.E.2
Krystal, J.H.3
Innis, R.B.4
-
97
-
-
20544459027
-
Methods of postmortem investigation of the human brain
-
Charney DS, Nester EJ, eds, 2 ed. New York, Oxford University Press
-
Lopez JF, Neale CR, Meader-Woodruff JH. Methods of postmortem investigation of the human brain. In: Charney DS, Nester EJ, eds, Neurobiology of Mental Illness 2 ed. New York, Oxford University Press 2004.
-
(2004)
Neurobiology of Mental Illness
-
-
Lopez, J.F.1
Neale, C.R.2
Meader-Woodruff, J.H.3
-
98
-
-
0030935403
-
Subgenual prefrontal cortex abnormalities in mood disorders
-
Drevets WC, Price JL, Simpson JR, Jr, et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997; 386: 824-7.
-
(1997)
Nature
, vol.386
, pp. 824-827
-
-
Drevets, W.C.1
Price, J.L.2
Simpson Jr, J.R.3
-
99
-
-
0001817672
-
Neuroimaging studies of depression
-
Charney DS, Nester EJ, Bunney BS, eds, New York, NY, Oxford University Press
-
Drevets WC, Gadde K, Krishnan R. Neuroimaging studies of depression. In: Charney DS, Nester EJ, Bunney BS, eds, Neurobiology of Mental Illness. New York, NY, Oxford University Press 1999; 394-418.
-
(1999)
Neurobiology of Mental Illness
, pp. 394-418
-
-
Drevets, W.C.1
Gadde, K.2
Krishnan, R.3
-
100
-
-
0036102199
-
Cell pathology in bipolar disorder
-
Rajkowska G. Cell pathology in bipolar disorder. Bipolar Disord 2002; 4: 129-116.
-
(2002)
Bipolar Disord
, vol.4
, pp. 129-116
-
-
Rajkowska, G.1
-
103
-
-
0028990811
-
T2 hyperintensities in bipolar disorder: Magnetic resonance imaging comparison and literature meta-analysis
-
Altshuler LL, Curran JG, Hauser P, et al. T2 hyperintensities in bipolar disorder: magnetic resonance imaging comparison and literature meta-analysis. Am J Psychiatry 1995; 152: 1139-44.
-
(1995)
Am J Psychiatry
, vol.152
, pp. 1139-1144
-
-
Altshuler, L.L.1
Curran, J.G.2
Hauser, P.3
-
104
-
-
0030756402
-
MRI findings in patients with affective disorder: A meta-analysis
-
Videbech P. MRI findings in patients with affective disorder: a meta-analysis. Acta Psychiatr Scand 1997; 96: 157-68.
-
(1997)
Acta Psychiatr Scand
, vol.96
, pp. 157-168
-
-
Videbech, P.1
-
105
-
-
0034667345
-
Neuroimaging studies of mood disorders
-
Drevets WC. Neuroimaging studies of mood disorders. Biol Psychiatry 2000; 48: 813-29.
-
(2000)
Biol Psychiatry
, vol.48
, pp. 813-829
-
-
Drevets, W.C.1
-
106
-
-
0034667301
-
Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells
-
Rajkowska G. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biol Psychiatry 2000; 48: 766-77.
-
(2000)
Biol Psychiatry
, vol.48
, pp. 766-777
-
-
Rajkowska, G.1
-
107
-
-
2442673159
-
Life stress, genes, and depression: Multiple path-ways lead to increased risk and new opportunities for intervention
-
Charney DS, Manji HK. Life stress, genes, and depression: multiple path-ways lead to increased risk and new opportunities for intervention. Sci STKE 2004; 2004: re5.
-
(2004)
Sci STKE 2004
-
-
Charney, D.S.1
Manji, H.K.2
-
108
-
-
0031968868
-
A new intellectual framework for psychiatry
-
Kandel ER. A new intellectual framework for psychiatry. Am J Psychiatry 1998; 155: 457-69.
-
(1998)
Am J Psychiatry
, vol.155
, pp. 457-469
-
-
Kandel, E.R.1
-
109
-
-
0032937814
-
Biology and the future of psychoanalysis: A new intellectual framework for psychiatry revisited
-
Kandel ER. Biology and the future of psychoanalysis: a new intellectual framework for psychiatry revisited. Am J Psychiatry 1999; 156: 505-24.
-
(1999)
Am J Psychiatry
, vol.156
, pp. 505-524
-
-
Kandel, E.R.1
-
110
-
-
0031681434
-
Novel therapeutic approaches beyond the serotonin receptor
-
Duman RS. Novel therapeutic approaches beyond the serotonin receptor. Biol Psychiatry 1998; 44: 324-35.
-
(1998)
Biol Psychiatry
, vol.44
, pp. 324-335
-
-
Duman, R.S.1
-
111
-
-
0033991319
-
Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus
-
Fujimaki K, Morinobu S, Duman RS. Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus. Neuropsychopharmacology 2000; 22: 42-51.
-
(2000)
Neuropsychopharmacology
, vol.22
, pp. 42-51
-
-
Fujimaki, K.1
Morinobu, S.2
Duman, R.S.3
-
113
-
-
0024269472
-
Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives
-
Bobon D, Breulet M, Gerard-Vandenbove MA, et al. Is phosphodiesterase inhibition a new mechanism of antidepressant action? A double blind double-dummy study between rolipram and desipramine in hospitalized major and/or endogenous depressives. Eur Arch Psychiatry Neurol Sci 1988; 238: 2-6.
-
(1988)
Eur Arch Psychiatry Neurol Sci
, vol.238
, pp. 2-6
-
-
Bobon, D.1
Breulet, M.2
Gerard-Vandenbove, M.A.3
-
114
-
-
0024319477
-
Rolipram in major depressive disorder: Results of a double-blind comparative study with imipramine
-
Hebenstreit GF, Fellerter K, Fichte K, et al. Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine. Pharmacopsychiatry 1989; 22:156-60.
-
(1989)
Pharmacopsychiatry
, vol.22
, pp. 156-160
-
-
Hebenstreit, G.F.1
Fellerter, K.2
Fichte, K.3
-
115
-
-
0035727846
-
The antidepressant and antiinflammatory effects of rolipram in the central nervous system
-
Zhu J, Mix E, Winblad B. The antidepressant and antiinflammatory effects of rolipram in the central nervous system. CNS Drug Rev 2001; 7: 387-98.
-
(2001)
CNS Drug Rev
, vol.7
, pp. 387-398
-
-
Zhu, J.1
Mix, E.2
Winblad, B.3
-
116
-
-
0035295487
-
Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics
-
Manji HK, Duman RS. Impairments of neuroplasticity and cellular resilience in severe mood disorders: implications for the development of novel therapeutics. Psychopharmacol Bull 2001; 35: 5-49.
-
(2001)
Psychopharmacol Bull
, vol.35
, pp. 5-49
-
-
Manji, H.K.1
Duman, R.S.2
-
117
-
-
0035755974
-
Histone deacetylases and cancer: Causes and therapies
-
Marks P, Rifkind RA, Richon VM, et al. Histone deacetylases and cancer: causes and therapies. Nat Rev Cancer 2001; 1: 194-202.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
-
118
-
-
0037452775
-
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
-
Hockly E, Richon VM, Woodman B, et al. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease. Proc Natl Acad Sci USA 2003; 100: 2041-6.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2041-2046
-
-
Hockly, E.1
Richon, V.M.2
Woodman, B.3
-
120
-
-
0042126365
-
Modulators of the glutamatergic system: Implications for the development of improved therapeutics in mood disorders
-
Zarate CA, Quiroz J, Payne J, Manji HK. Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders. Psychopharmacol Bull 2002; 36:35-83.
-
(2002)
Psychopharmacol Bull
, vol.36
, pp. 35-83
-
-
Zarate, C.A.1
Quiroz, J.2
Payne, J.3
Manji, H.K.4
-
121
-
-
0028828225
-
Distinct components of spatial learning revealed by prior training and NMDA receptor blockade
-
Bannerman DM, Good MA, Butcher SP, Ramsay M, Morris RG. Distinct components of spatial learning revealed by prior training and NMDA receptor blockade. Nature 1995; 378: 182-6.
-
(1995)
Nature
, vol.378
, pp. 182-186
-
-
Bannerman, D.M.1
Good, M.A.2
Butcher, S.P.3
Ramsay, M.4
Morris, R.G.5
-
122
-
-
0027988316
-
Long-term potentiation. A question of reliability
-
Collingridge GL. Long-term potentiation. A question of reliability. Nature 1994; 371: 652-3.
-
(1994)
Nature
, vol.371
, pp. 652-653
-
-
Collingridge, G.L.1
-
123
-
-
0027992583
-
Phenylglycine derivatives as antagonists of metabotropic glutamate receptors
-
Watkins J, Collingridge G. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends Pharmacol Sci 1994; 15: 333-42.
-
(1994)
Trends Pharmacol Sci
, vol.15
, pp. 333-342
-
-
Watkins, J.1
Collingridge, G.2
-
125
-
-
0037385145
-
A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder
-
Bowden CL, Calabrese JR, Sachs G, et al. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch Gen Psychiatry 2003; 60: 392-400.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 392-400
-
-
Bowden, C.L.1
Calabrese, J.R.2
Sachs, G.3
-
126
-
-
0033004838
-
A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group
-
Calabrese JR, Bowden CL, Sachs GS, et al. A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. J Clin Psychiatry 1999; 60: 79-88.
-
(1999)
J Clin Psychiatry
, vol.60
, pp. 79-88
-
-
Calabrese, J.R.1
Bowden, C.L.2
Sachs, G.S.3
-
127
-
-
0027762836
-
The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1
-
Martin D, Thompson MA, Nadler JV. The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1. Eur J Pharmacol 1993; 250: 473-6.
-
(1993)
Eur J Pharmacol
, vol.250
, pp. 473-476
-
-
Martin, D.1
Thompson, M.A.2
Nadler, J.V.3
-
128
-
-
0037679232
-
Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with obsessive-compulsive disorder and major depressive disorder
-
Coric V, Milanovic S, Wasylink S, et al. Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with obsessive-compulsive disorder and major depressive disorder. Psychopharmacology 2003; 167: 219-220.
-
(2003)
Psychopharmacology
, vol.167
, pp. 219-220
-
-
Coric, V.1
Milanovic, S.2
Wasylink, S.3
-
129
-
-
7444247835
-
Riluzole augmentation for treatment-resistant depression
-
Sanacora G, Kendell SF, Fenton L, Coric V, Krystal JH. Riluzole augmentation for treatment-resistant depression. Am J Psychiatry 2004; 161: 2132.
-
(2004)
Am J Psychiatry
, vol.161
, pp. 2132
-
-
Sanacora, G.1
Kendell, S.F.2
Fenton, L.3
Coric, V.4
Krystal, J.H.5
-
130
-
-
2342580069
-
Case report: Successful riluzole augmentation therapy in treatment-resistant bipolar depression following the development of rash with lamotrigine
-
Singh J, Zarate CA, Jr., Krystal AD. Case report: Successful riluzole augmentation therapy in treatment-resistant bipolar depression following the development of rash with lamotrigine. Psychopharmacology (Berl) 2004; 173: 227-8.
-
(2004)
Psychopharmacology (Berl)
, vol.173
, pp. 227-228
-
-
Singh, J.1
Zarate Jr., C.A.2
Krystal, A.D.3
-
131
-
-
1442264398
-
An open-label trial of riluzole in patients with treatment-resistant major depression
-
Zarate CA, Jr, Payne JL, Quiroz J, et al. An open-label trial of riluzole in patients with treatment-resistant major depression. Am J Psychiatry 2004; 161: 171-4.
-
(2004)
Am J Psychiatry
, vol.161
, pp. 171-174
-
-
Zarate Jr, C.A.1
Payne, J.L.2
Quiroz, J.3
-
132
-
-
13444310754
-
An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression
-
Zarate CA, Jr, Quiroz JA, Singh JB, et al. An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression. Biol Psychiatry 2005; 57: 430-2.
-
(2005)
Biol Psychiatry
, vol.57
, pp. 430-432
-
-
Zarate Jr, C.A.1
Quiroz, J.A.2
Singh, J.B.3
-
133
-
-
0033969685
-
Antidepressant effects of ketamine in depressed patients
-
Berman RM, Cappiello A. Anand A, et al. Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 2000; 47: 351-4.
-
(2000)
Biol Psychiatry
, vol.47
, pp. 351-354
-
-
Berman, R.M.1
Cappiello, A.2
Anand, A.3
-
134
-
-
1442284539
-
Glycogen synthase kinase-3: A target for novel bipolar disorder treatments
-
Gould TD, Zarate CA, Manji HK. Glycogen synthase kinase-3: a target for novel bipolar disorder treatments. J Clin Psychiatry 2004; 65: 10-21.
-
(2004)
J Clin Psychiatry
, vol.65
, pp. 10-21
-
-
Gould, T.D.1
Zarate, C.A.2
Manji, H.K.3
-
135
-
-
1542313961
-
Preliminary randomized, double-blind, placebo-controlled trial of pramipexole added to mood stabilizers for treatment-resistant bipolar depression
-
Goldberg JF, Burdick KE, Endick CJ. Preliminary randomized, double-blind, placebo-controlled trial of pramipexole added to mood stabilizers for treatment-resistant bipolar depression. Am J Psychiatry 2004; 161: 564-6.
-
(2004)
Am J Psychiatry
, vol.161
, pp. 564-566
-
-
Goldberg, J.F.1
Burdick, K.E.2
Endick, C.J.3
-
136
-
-
3042561718
-
Pramipexole for bipolar II depression: A placebo-controlled proof of concept study
-
Zarate CA, Jr, Payne JL, Singh J, et al. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biol Psychiatry 2004; 56: 54-60.
-
(2004)
Biol Psychiatry
, vol.56
, pp. 54-60
-
-
Zarate Jr, C.A.1
Payne, J.L.2
Singh, J.3
-
137
-
-
0035875146
-
The role of childhood trauma in the neurobiology of mood and anxiety disorders: Preclinical and clinical studies
-
Heim C, Nemeroff CB. The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry 2001; 49: 1023-39.
-
(2001)
Biol Psychiatry
, vol.49
, pp. 1023-1039
-
-
Heim, C.1
Nemeroff, C.B.2
-
138
-
-
0032912252
-
Stress and hippocampal plasticity
-
McEwen BS. Stress and hippocampal plasticity. Annu Rev Neurosci 1999; 22: 105-22.
-
(1999)
Annu Rev Neurosci
, vol.22
, pp. 105-122
-
-
McEwen, B.S.1
-
139
-
-
0034667292
-
Effects of adverse experiences for brain structure and function
-
McEwen BS. Effects of adverse experiences for brain structure and function. Biol Psychiatry 2000; 48: 721-31.
-
(2000)
Biol Psychiatry
, vol.48
, pp. 721-731
-
-
McEwen, B.S.1
-
140
-
-
0034454682
-
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
-
Sapolsky RM, Romero LM, Munck AU. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr Rev 2000; 21: 55-89.
-
(2000)
Endocr Rev
, vol.21
, pp. 55-89
-
-
Sapolsky, R.M.1
Romero, L.M.2
Munck, A.U.3
-
142
-
-
33745786711
-
Toward constructing an endophenotype strategy for bipolar disorders
-
Hasler G, Drevets WC, Gould TD, Gottesman II, Manji HK. Toward constructing an endophenotype strategy for bipolar disorders. Biol Psychiatry 2006; 60(2): 92-105.
-
(2006)
Biol Psychiatry
, vol.60
, Issue.2
, pp. 92-105
-
-
Hasler, G.1
Drevets, W.C.2
Gould, T.D.3
Gottesman, I.I.4
Manji, H.K.5
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