-
1
-
-
33746633882
-
Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways
-
Ambree O., Leimer U., Herring A., Gortz N., Sachser N., Heneka M.T., Paulus W., and Keyvani K. Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways. Am. J. Pathol. 169 (2006) 544-552
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 544-552
-
-
Ambree, O.1
Leimer, U.2
Herring, A.3
Gortz, N.4
Sachser, N.5
Heneka, M.T.6
Paulus, W.7
Keyvani, K.8
-
2
-
-
33846787025
-
Stimulation of endogenous neurogenesis by anti-EFRH immunization in a transgenic mouse model of Alzheimer's disease
-
Becker M., Lavie V., and Solomon B. Stimulation of endogenous neurogenesis by anti-EFRH immunization in a transgenic mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 1691-1696
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 1691-1696
-
-
Becker, M.1
Lavie, V.2
Solomon, B.3
-
3
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor protein
-
Borchelt D.R., Ratovitski T., Van Lare J., Lee M.K., Gonzales V., Jenkins N.A., Copeland N.G., Price D.L., and Sisodia S.S. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor protein. Neuron 19 (1997) 939-945
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
4
-
-
0032558784
-
Neuron loss in APP transgenic mice [letter]
-
Calhoun M.E., Wiederhold K.H., Abramowski D., Phinney A.L., Probst A., Sturchler-Pierrat C., Staufenbiel M., Sommer B., and Jucker M. Neuron loss in APP transgenic mice [letter]. Nature 395 (1998) 755-756
-
(1998)
Nature
, vol.395
, pp. 755-756
-
-
Calhoun, M.E.1
Wiederhold, K.H.2
Abramowski, D.3
Phinney, A.L.4
Probst, A.5
Sturchler-Pierrat, C.6
Staufenbiel, M.7
Sommer, B.8
Jucker, M.9
-
5
-
-
9844255568
-
Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice
-
Carlson G.A., Borchelt D.R., Dake A., Turner S., Danielson V., Coffin J.D., Eckman C., Meiners J., Nilsen S., Younkin S.G., and Hsiao K. Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice. Hum. Mol. Genet. 6 11 (1997) 1951-1959
-
(1997)
Hum. Mol. Genet.
, vol.6
, Issue.11
, pp. 1951-1959
-
-
Carlson, G.A.1
Borchelt, D.R.2
Dake, A.3
Turner, S.4
Danielson, V.5
Coffin, J.D.6
Eckman, C.7
Meiners, J.8
Nilsen, S.9
Younkin, S.G.10
Hsiao, K.11
-
6
-
-
0034700480
-
A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
-
Chen G., Chen K.S., Knox J., Inglis J., Bernard A., Martin S.J., Justice A., McConlogue L., Games D., Freedman S.B., and Morris R.G. A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease. Nature 408 (2000) 975-979
-
(2000)
Nature
, vol.408
, pp. 975-979
-
-
Chen, G.1
Chen, K.S.2
Knox, J.3
Inglis, J.4
Bernard, A.5
Martin, S.J.6
Justice, A.7
McConlogue, L.8
Games, D.9
Freedman, S.B.10
Morris, R.G.11
-
7
-
-
33645107862
-
Neurogenesis in the adult hippocampus
-
Christie B.R., and Cameron H.A. Neurogenesis in the adult hippocampus. Hippocampus 16 (2006) 199-207
-
(2006)
Hippocampus
, vol.16
, pp. 199-207
-
-
Christie, B.R.1
Cameron, H.A.2
-
8
-
-
33846472229
-
Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms
-
Costa D.A., Cracchiolo J.R., Bachstetter A.D., Hughes T.F., Bales K.R., Paul S.M., Mervis R.F., Arendash G.W., and Potter H. Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms. Neurobiol. Aging (2006)
-
(2006)
Neurobiol. Aging
-
-
Costa, D.A.1
Cracchiolo, J.R.2
Bachstetter, A.D.3
Hughes, T.F.4
Bales, K.R.5
Paul, S.M.6
Mervis, R.F.7
Arendash, G.W.8
Potter, H.9
-
9
-
-
0023762975
-
Clinico-pathological studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease
-
Crystal H., Dickson D., Fuld P., Masur D., Scott R., Mehler M., Masdeu J., Kawas C., Aronson M., and Wolfson L. Clinico-pathological studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease. Neurology 38 (1988) 1682-1687
-
(1988)
Neurology
, vol.38
, pp. 1682-1687
-
-
Crystal, H.1
Dickson, D.2
Fuld, P.3
Masur, D.4
Scott, R.5
Mehler, M.6
Masdeu, J.7
Kawas, C.8
Aronson, M.9
Wolfson, L.10
-
11
-
-
0033501744
-
Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein
-
Dodart J.C., Meziane H., Mathis C., Bales K.R., Paul S.M., and Ungerer A. Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein. Behav. Neurosci. 113 (1999) 982-990
-
(1999)
Behav. Neurosci.
, vol.113
, pp. 982-990
-
-
Dodart, J.C.1
Meziane, H.2
Mathis, C.3
Bales, K.R.4
Paul, S.M.5
Ungerer, A.6
-
13
-
-
32544460592
-
Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease
-
Donovan M.H., Yazdani U., Norris R.D., Games D., German D.C., and Eisch A.J. Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. J. Comp. Neurol. 495 (2006) 70-83
-
(2006)
J. Comp. Neurol.
, vol.495
, pp. 70-83
-
-
Donovan, M.H.1
Yazdani, U.2
Norris, R.D.3
Games, D.4
German, D.C.5
Eisch, A.J.6
-
14
-
-
0344742225
-
Inflammation is detrimental for neurogenesis in adult brain
-
Ekdahl C.T., Claasen J.H., Bonde S., Kokaia Z., and Lindvall O. Inflammation is detrimental for neurogenesis in adult brain. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 13632-13637
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 13632-13637
-
-
Ekdahl, C.T.1
Claasen, J.H.2
Bonde, S.3
Kokaia, Z.4
Lindvall, O.5
-
15
-
-
18244391974
-
Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces
-
Feng R., Rampon C., Tang Y.P., Shrom D., Jin J., Kyin M., Sopher B., Miller M.W., Ware C.B., Martin G.M., Kim S.H., Langdon R.B., Sisodia S.S., and Tsien J.Z. Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces. Neuron 32 (2001) 911-926
-
(2001)
Neuron
, vol.32
, pp. 911-926
-
-
Feng, R.1
Rampon, C.2
Tang, Y.P.3
Shrom, D.4
Jin, J.5
Kyin, M.6
Sopher, B.7
Miller, M.W.8
Ware, C.B.9
Martin, G.M.10
Kim, S.H.11
Langdon, R.B.12
Sisodia, S.S.13
Tsien, J.Z.14
-
16
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., and Gillespie F. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 373 (1995) 523-527
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
-
17
-
-
0034988318
-
Correlation between cognitive deficits and Aβ deposits in transgenic APP + PS1 mice
-
Gordon M.N., King D.L., Diamond D.M., Jantzen P.T., Boyett K.L., Hope C.E., Hatcher J.M., DiCarlo G., Gottschal P., Morgan D., and Arendash G.W. Correlation between cognitive deficits and Aβ deposits in transgenic APP + PS1 mice. Neurobiol. Aging 22 (2001) 377-385
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 377-385
-
-
Gordon, M.N.1
King, D.L.2
Diamond, D.M.3
Jantzen, P.T.4
Boyett, K.L.5
Hope, C.E.6
Hatcher, J.M.7
DiCarlo, G.8
Gottschal, P.9
Morgan, D.10
Arendash, G.W.11
-
18
-
-
0036175608
-
Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1 + APP mouse
-
Gordon M.N., Holcomb L.A., Jantzen P.T., DiCarlo G., Wilcock D., Boyett K.L., Connor K., Melachrino J.O., O'Callaghan J.P., and Morgan D. Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1 + APP mouse. Exp. Neurol. 173 (2002) 183-195
-
(2002)
Exp. Neurol.
, vol.173
, pp. 183-195
-
-
Gordon, M.N.1
Holcomb, L.A.2
Jantzen, P.T.3
DiCarlo, G.4
Wilcock, D.5
Boyett, K.L.6
Connor, K.7
Melachrino, J.O.8
O'Callaghan, J.P.9
Morgan, D.10
-
19
-
-
0033363319
-
Learning enhances adult neurogenesis in the hippocampal formation
-
Gould E., Beylin A., Tanapat P., Reeves A., and Shors T.J. Learning enhances adult neurogenesis in the hippocampal formation. Nat. Neurosci. 2 (1999) 260-265
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 260-265
-
-
Gould, E.1
Beylin, A.2
Tanapat, P.3
Reeves, A.4
Shors, T.J.5
-
20
-
-
0029949755
-
APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology
-
Greenberg B.D., Savage M.J., Howland D.S., Ali S.M., Siedlak S.L., Perry G., Siman R., and Scott R.W. APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology. Neurobiol. Aging 17 (1996) 153-171
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 153-171
-
-
Greenberg, B.D.1
Savage, M.J.2
Howland, D.S.3
Ali, S.M.4
Siedlak, S.L.5
Perry, G.6
Siman, R.7
Scott, R.W.8
-
21
-
-
0042362874
-
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
-
Haughey N.J., Nath A., Chan S.L., Borchard A.C., Rao M.S., and Mattson M.P. Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J. Neurochem. 83 (2002) 1509-1524
-
(2002)
J. Neurochem.
, vol.83
, pp. 1509-1524
-
-
Haughey, N.J.1
Nath, A.2
Chan, S.L.3
Borchard, A.C.4
Rao, M.S.5
Mattson, M.P.6
-
22
-
-
0033514060
-
Peripheral administration of novel anti-inflammatories can attenuate the effects of chronic inflammation within the CNS
-
Hauss-Wegrzyniak B., Willard L.B., Del Soldato P., Pepeu G., and Wenk G.L. Peripheral administration of novel anti-inflammatories can attenuate the effects of chronic inflammation within the CNS. Brain Res. 815 (1999) 36-43
-
(1999)
Brain Res.
, vol.815
, pp. 36-43
-
-
Hauss-Wegrzyniak, B.1
Willard, L.B.2
Del Soldato, P.3
Pepeu, G.4
Wenk, G.L.5
-
23
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L.A., Gordon M.N., McGowan E., Yu X., Benkovic S., Jantzen P., Wright K., Saad I., Mueller R., Morgan D., Sanders S., Zehr C., O'Campo K., Hardy J., Prada C.M., Eckman C., Younkin S., Hsiao K., and Duff K. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat. Med. 4 (1998) 97-100
-
(1998)
Nat. Med.
, vol.4
, pp. 97-100
-
-
Holcomb, L.A.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
24
-
-
0032756213
-
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits
-
Holcomb L.A., Gordon M.N., Jantzen P., Hsiao K., Duff K., and Morgan D. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behav. Gen. 29 (1999) 177-185
-
(1999)
Behav. Gen.
, vol.29
, pp. 177-185
-
-
Holcomb, L.A.1
Gordon, M.N.2
Jantzen, P.3
Hsiao, K.4
Duff, K.5
Morgan, D.6
-
25
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia A.Y., Masliah E., McConlogue L., Yu G.Q., Tatsuno G., Hu K., Kholodenko D., Malenka R.C., Nicoll R.A., and Mucke L. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 3228-3233
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
26
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., and Cole G. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274 (1996) 99-102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
27
-
-
0030612033
-
APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1
-
Irizarry M.C., McNamara M., Fedorchak K., Hsiao K., and Hyman B.T. APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J. Neuropathol. Exp. Neurol. 56 (1997) 965-973
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 965-973
-
-
Irizarry, M.C.1
McNamara, M.2
Fedorchak, K.3
Hsiao, K.4
Hyman, B.T.5
-
28
-
-
21144456098
-
Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease
-
Jankowsky J.L., Melnikova T., Fadale D.J., Xu G.M., Slunt H.H., Gonzales V., Younkin L.H., Younkin S.G., Borchelt D.R., and Savonenko A.V. Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease. J. Neurosci. 25 (2005) 5217-5224
-
(2005)
J. Neurosci.
, vol.25
, pp. 5217-5224
-
-
Jankowsky, J.L.1
Melnikova, T.2
Fadale, D.J.3
Xu, G.M.4
Slunt, H.H.5
Gonzales, V.6
Younkin, L.H.7
Younkin, S.G.8
Borchelt, D.R.9
Savonenko, A.V.10
-
29
-
-
0034700471
-
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus C., Pearson J., McLaurin J., Mathews P.M., Jiang Y., Schmidt S.D., Chishti M.A., Horne P., Heslin D., French J., Mount H.T., Nixon R.A., Mercken M., Bergeron C., Fraser P.E., George-Hyslop P., and Westaway D. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 408 (2000) 979-982
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
Mount, H.T.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
George-Hyslop, P.16
Westaway, D.17
-
30
-
-
4444269849
-
Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice
-
Jin K., Galvan V., Xie L., Mao X.O., Gorostiza O.F., Bredesen D.E., and Greenberg D.A. Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 13363-13367
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 13363-13367
-
-
Jin, K.1
Galvan, V.2
Xie, L.3
Mao, X.O.4
Gorostiza, O.F.5
Bredesen, D.E.6
Greenberg, D.A.7
-
31
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R., Head E., Thompson J.L., McIntire T.M., Milton S.C., Cotman C.W., and Glabe C.G. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300 (2003) 486-489
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
32
-
-
0030937293
-
More hippocampal neurons in adult mice living in an enriched environment
-
Kempermann G., Kuhn H.G., and Gage F.H. More hippocampal neurons in adult mice living in an enriched environment. Nature 386 (1997) 493-495
-
(1997)
Nature
, vol.386
, pp. 493-495
-
-
Kempermann, G.1
Kuhn, H.G.2
Gage, F.H.3
-
33
-
-
2542455537
-
Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease
-
Klein W.L., Stine Jr. W.B., and Teplow D.B. Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease. Neurobiol. Aging 25 (2004) 569-580
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 569-580
-
-
Klein, W.L.1
Stine Jr., W.B.2
Teplow, D.B.3
-
34
-
-
0242693294
-
Neuropathology of cognitively normal elderly
-
Knopman D.S., Parisi J.E., Salviati A., Floriach-Robert M., Boeve B.F., Ivnik R.J., Smith G.E., Dickson D.W., Johnson K.A., Petersen L.E., McDonald W.C., Braak H., and Petersen R.C. Neuropathology of cognitively normal elderly. J. Neuropathol. Exp. Neurol. 62 (2003) 1087-1095
-
(2003)
J. Neuropathol. Exp. Neurol.
, vol.62
, pp. 1087-1095
-
-
Knopman, D.S.1
Parisi, J.E.2
Salviati, A.3
Floriach-Robert, M.4
Boeve, B.F.5
Ivnik, R.J.6
Smith, G.E.7
Dickson, D.W.8
Johnson, K.A.9
Petersen, L.E.10
McDonald, W.C.11
Braak, H.12
Petersen, R.C.13
-
35
-
-
0035807829
-
Specific spatial learning deficits become severe with age in beta-amyloid precursor protein transgenic mice that harbor diffuse beta-amyloid deposits but do not form plaques
-
Koistinaho M., Ort M., Cimadevilla J.M., Vondrous R., Cordell B., Koistinaho J., Bures J., and Higgins L.S. Specific spatial learning deficits become severe with age in beta-amyloid precursor protein transgenic mice that harbor diffuse beta-amyloid deposits but do not form plaques. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 14675-14680
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 14675-14680
-
-
Koistinaho, M.1
Ort, M.2
Cimadevilla, J.M.3
Vondrous, R.4
Cordell, B.5
Koistinaho, J.6
Bures, J.7
Higgins, L.S.8
-
36
-
-
0029863342
-
Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation
-
Kuhn H.G., Dickinson-Anson H., and Gage F.H. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci. 16 (1996) 2027-2033
-
(1996)
J. Neurosci.
, vol.16
, pp. 2027-2033
-
-
Kuhn, H.G.1
Dickinson-Anson, H.2
Gage, F.H.3
-
37
-
-
20044377403
-
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice
-
Lazarov O., Robinson J., Tang Y.P., Hairston I.S., Korade-Mirnics Z., Lee V.M., Hersh L.B., Sapolsky R.M., Mirnics K., and Sisodia S.S. Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell 120 (2005) 701-713
-
(2005)
Cell
, vol.120
, pp. 701-713
-
-
Lazarov, O.1
Robinson, J.2
Tang, Y.P.3
Hairston, I.S.4
Korade-Mirnics, Z.5
Lee, V.M.6
Hersh, L.B.7
Sapolsky, R.M.8
Mirnics, K.9
Sisodia, S.S.10
-
38
-
-
2342572400
-
Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein
-
Lee K.W., Lee S.H., Kim H., Song J.S., Yang S.D., Paik S.G., and Han P.L. Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein. J. Neurosci. Res. 76 (2004) 572-580
-
(2004)
J. Neurosci. Res.
, vol.76
, pp. 572-580
-
-
Lee, K.W.1
Lee, S.H.2
Kim, H.3
Song, J.S.4
Yang, S.D.5
Paik, S.G.6
Han, P.L.7
-
39
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
Lesne S., Koh M.T., Kotilinek L., Kayed R., Glabe C.G., Yang A., Gallagher M., and Ashe K.H. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440 (2006) 352-357
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesne, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
Gallagher, M.7
Ashe, K.H.8
-
40
-
-
33645098296
-
Is there a link between adult neurogenesis and learning?
-
Leuner B., Gould E., and Shors T.J. Is there a link between adult neurogenesis and learning?. Hippocampus 16 (2006) 216-224
-
(2006)
Hippocampus
, vol.16
, pp. 216-224
-
-
Leuner, B.1
Gould, E.2
Shors, T.J.3
-
41
-
-
0029795517
-
Inflammation, Abeta deposition and neurofibrillary tangle formation as correlates of Alzheimer's disease neurodegeneration
-
Lue L., Brachova L., Civin H., and Rogers J. Inflammation, Abeta deposition and neurofibrillary tangle formation as correlates of Alzheimer's disease neurodegeneration. J. Neuropathol. Exp. Neurol. 55 (1996) 1083-1088
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 1083-1088
-
-
Lue, L.1
Brachova, L.2
Civin, H.3
Rogers, J.4
-
42
-
-
0038182466
-
Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat
-
Madsen T.M., Kristjansen P.E., Bolwig T.G., and Wortwein G. Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat. Neuroscience 119 (2003) 635-642
-
(2003)
Neuroscience
, vol.119
, pp. 635-642
-
-
Madsen, T.M.1
Kristjansen, P.E.2
Bolwig, T.G.3
Wortwein, G.4
-
43
-
-
0345189366
-
Inflammatory blockade restores adult hippocampal neurogenesis
-
Monje M.L., Toda H., and Palmer T.D. Inflammatory blockade restores adult hippocampal neurogenesis. Science 302 (2003) 1760-1765
-
(2003)
Science
, vol.302
, pp. 1760-1765
-
-
Monje, M.L.1
Toda, H.2
Palmer, T.D.3
-
44
-
-
0029055738
-
Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein
-
Moran P.M., Higgins L.S., Cordell B., and Moser P.C. Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 5341-5345
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 5341-5345
-
-
Moran, P.M.1
Higgins, L.S.2
Cordell, B.3
Moser, P.C.4
-
45
-
-
84984755327
-
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan D., Diamond D.M., Gottschall P.E., Ugen K.E., Dickey C., Hardy J., Duff K., Jantzen P., DiCarlo G., Wilcock D., Connor K., Hatcher J., Hope C., Gordon M., and Arendash G.W. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature 408 (2000) 982-985
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
Duff, K.7
Jantzen, P.8
DiCarlo, G.9
Wilcock, D.10
Connor, K.11
Hatcher, J.12
Hope, C.13
Gordon, M.14
Arendash, G.W.15
-
46
-
-
24644438615
-
Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics
-
Morgan D., Gordon M.N., Tan J., Wilcock D., and Rojiani A.M. Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics. J. Neuropathol. Exp. Neurol. 64 (2005) 743-753
-
(2005)
J. Neuropathol. Exp. Neurol.
, vol.64
, pp. 743-753
-
-
Morgan, D.1
Gordon, M.N.2
Tan, J.3
Wilcock, D.4
Rojiani, A.M.5
-
47
-
-
0035168927
-
Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease
-
Morris J.C., and Price A.L. Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease. J. Mol. Neurosci. 17 (2001) 101-118
-
(2001)
J. Mol. Neurosci.
, vol.17
, pp. 101-118
-
-
Morris, J.C.1
Price, A.L.2
-
48
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
-
Oddo S., Caccamo A., Shepherd J.D., Murphy M.P., Golde T.E., Kayed R., Metherate R., Mattson M.P., Akbari Y., and LaFerla F.M. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39 (2003) 409-421
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
49
-
-
0346055155
-
BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease
-
Ohno M., Sametsky E.A., Younkin L.H., Oakley H., Younkin S.G., Citron M., Vassar R., and Disterhoft J.F. BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease. Neuron 41 (2004) 27-33
-
(2004)
Neuron
, vol.41
, pp. 27-33
-
-
Ohno, M.1
Sametsky, E.A.2
Younkin, L.H.3
Oakley, H.4
Younkin, S.G.5
Citron, M.6
Vassar, R.7
Disterhoft, J.F.8
-
50
-
-
3843075154
-
Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis
-
Raber J., Rola R., LeFevour A., Morhardt D., Curley J., Mizumatsu S., VandenBerg S.R., and Fike J.R. Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis. Radiat. Res. 162 (2004) 39-47
-
(2004)
Radiat. Res.
, vol.162
, pp. 39-47
-
-
Raber, J.1
Rola, R.2
LeFevour, A.3
Morhardt, D.4
Curley, J.5
Mizumatsu, S.6
VandenBerg, S.R.7
Fike, J.R.8
-
51
-
-
10744230072
-
Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease
-
Richardson J.C., Kendal C.E., Anderson R., Priest F., Gower E., Soden P., Gray R., Topps S., Howlett D.R., Lavender D., Clarke N.J., Barnes J.C., Haworth R., Stewart M.G., and Rupniak H.T. Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease. Neuroscience 122 (2003) 213-228
-
(2003)
Neuroscience
, vol.122
, pp. 213-228
-
-
Richardson, J.C.1
Kendal, C.E.2
Anderson, R.3
Priest, F.4
Gower, E.5
Soden, P.6
Gray, R.7
Topps, S.8
Howlett, D.R.9
Lavender, D.10
Clarke, N.J.11
Barnes, J.C.12
Haworth, R.13
Stewart, M.G.14
Rupniak, H.T.15
-
52
-
-
33947389569
-
Effects of cerebrolysintrade mark on neurogenesis in an APP transgenic model of Alzheimer's disease
-
Rockenstein E., Mante M., Adame A., Crews L., Moessler H., and Masliah E. Effects of cerebrolysintrade mark on neurogenesis in an APP transgenic model of Alzheimer's disease. Acta Neuropathol. (Berl). 113 (2007) 265-275
-
(2007)
Acta Neuropathol. (Berl).
, vol.113
, pp. 265-275
-
-
Rockenstein, E.1
Mante, M.2
Adame, A.3
Crews, L.4
Moessler, H.5
Masliah, E.6
-
53
-
-
3042799716
-
Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice
-
Rola R., Raber J., Rizk A., Otsuka S., VandenBerg S.R., Morhardt D.R., and Fike J.R. Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice. Exp. Neurol. 188 (2004) 316-330
-
(2004)
Exp. Neurol.
, vol.188
, pp. 316-330
-
-
Rola, R.1
Raber, J.2
Rizk, A.3
Otsuka, S.4
VandenBerg, S.R.5
Morhardt, D.R.6
Fike, J.R.7
-
54
-
-
0035868717
-
Neurogenesis in the adult is involved in the formation of trace memories
-
Shors T.J., Miesegaes G., Beylin A., Zhao M., Rydel T., and Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature 410 (2001) 372-376
-
(2001)
Nature
, vol.410
, pp. 372-376
-
-
Shors, T.J.1
Miesegaes, G.2
Beylin, A.3
Zhao, M.4
Rydel, T.5
Gould, E.6
-
55
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C., Abramowski D., Duke M., Wiederhold K.H., Mistl C., Rothacher S., Ledermann B., Burki K., Frey P., Paganetti P.A., Waridel C., Calhoun M.E., Jucker M., Probst A., Staufenbiel M., and Sommer B. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 13287-13292
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
56
-
-
0033872024
-
Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss
-
Takeuchi A., Irizarry M.C., Duff K., Saido T.C., Hsiao A.K., Hasegawa M., Mann D.M., Hyman B.T., and Iwatsubo T. Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. Am. J. Pathol. 157 (2000) 331-339
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 331-339
-
-
Takeuchi, A.1
Irizarry, M.C.2
Duff, K.3
Saido, T.C.4
Hsiao, A.K.5
Hasegawa, M.6
Mann, D.M.7
Hyman, B.T.8
Iwatsubo, T.9
-
57
-
-
2542584749
-
Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice
-
Trinchese F., Liu S., Battaglia F., Walter S., Mathews P.M., and Arancio O. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice. Ann. Neurol. 55 (2004) 801-814
-
(2004)
Ann. Neurol.
, vol.55
, pp. 801-814
-
-
Trinchese, F.1
Liu, S.2
Battaglia, F.3
Walter, S.4
Mathews, P.M.5
Arancio, O.6
-
58
-
-
0033539607
-
Running enhances neurogenesis, learning, and long-term potentiation in mice
-
van Praag H., Christie B.R., Sejnowski T.J., and Gage F.H. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 13427-13431
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 13427-13431
-
-
van Praag, H.1
Christie, B.R.2
Sejnowski, T.J.3
Gage, F.H.4
-
59
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., Rowan M.J., and Selkoe D.J. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416 (2002) 535-539
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
60
-
-
0036314949
-
Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice
-
Wen P.H., Shao X., Shao Z., Hof P.R., Wisniewski T., Kelley K., Friedrich Jr. V.L., Ho L., Pasinetti G.M., Shioi J., Robakis N.K., and Elder G.A. Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice. Neurobiol. Dis. 10 (2002) 8-19
-
(2002)
Neurobiol. Dis.
, vol.10
, pp. 8-19
-
-
Wen, P.H.1
Shao, X.2
Shao, Z.3
Hof, P.R.4
Wisniewski, T.5
Kelley, K.6
Friedrich Jr., V.L.7
Ho, L.8
Pasinetti, G.M.9
Shioi, J.10
Robakis, N.K.11
Elder, G.A.12
-
61
-
-
3042751874
-
The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice
-
Wen P.H., Hof P.R., Chen X., Gluck K., Austin G., Younkin S.G., Younkin L.H., DeGasperi R., Gama Sosa M.A., Robakis N.K., Haroutunian V., and Elder G.A. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice. Exp. Neurol. 188 (2004) 224-237
-
(2004)
Exp. Neurol.
, vol.188
, pp. 224-237
-
-
Wen, P.H.1
Hof, P.R.2
Chen, X.3
Gluck, K.4
Austin, G.5
Younkin, S.G.6
Younkin, L.H.7
DeGasperi, R.8
Gama Sosa, M.A.9
Robakis, N.K.10
Haroutunian, V.11
Elder, G.A.12
-
62
-
-
0036489445
-
The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease
-
Westerman M.A., Cooper-Blacketer D., Mariash A., Kotilinek L., Kawarabayashi T., Younkin L.H., Carlson G.A., Younkin S.G., and Ashe K.H. The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease. J. Neurosci. 22 (2002) 1858-1867
-
(2002)
J. Neurosci.
, vol.22
, pp. 1858-1867
-
-
Westerman, M.A.1
Cooper-Blacketer, D.2
Mariash, A.3
Kotilinek, L.4
Kawarabayashi, T.5
Younkin, L.H.6
Carlson, G.A.7
Younkin, S.G.8
Ashe, K.H.9
-
63
-
-
3042839092
-
Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition
-
Wilcock D.M., Rojiani A., Rosenthal A., Levkowitz G., Subbarao S., Alamed J., Wilson D., Wilson N., Freeman M.J., Gordon M.N., and Morgan D. Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition. J. Neurosci. 24 (2004) 6144-6151
-
(2004)
J. Neurosci.
, vol.24
, pp. 6144-6151
-
-
Wilcock, D.M.1
Rojiani, A.2
Rosenthal, A.3
Levkowitz, G.4
Subbarao, S.5
Alamed, J.6
Wilson, D.7
Wilson, N.8
Freeman, M.J.9
Gordon, M.N.10
Morgan, D.11
-
64
-
-
33751550928
-
Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease
-
Wolf S.A., Kronenberg G., Lehmann K., Blankenship A., Overall R., Staufenbiel M., and Kempermann G. Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease. Biol. Psychiatry 60 (2006) 1314-1323
-
(2006)
Biol. Psychiatry
, vol.60
, pp. 1314-1323
-
-
Wolf, S.A.1
Kronenberg, G.2
Lehmann, K.3
Blankenship, A.4
Overall, R.5
Staufenbiel, M.6
Kempermann, G.7
-
65
-
-
0033391197
-
Mice transgenic for a human amyloid precursor protein promoter-lacZ reporter construct
-
Wright K.L., Morgan D.G., Yu X., Goss J.R., Salbaum J.M., Duff K., and Gordon M.N. Mice transgenic for a human amyloid precursor protein promoter-lacZ reporter construct. J. Mol. Neurosci. 13 (1999) 111-120
-
(1999)
J. Mol. Neurosci.
, vol.13
, pp. 111-120
-
-
Wright, K.L.1
Morgan, D.G.2
Yu, X.3
Goss, J.R.4
Salbaum, J.M.5
Duff, K.6
Gordon, M.N.7
-
66
-
-
33748471099
-
Inflammation in Alzheimer disease: driving force, bystander or beneficial response?
-
Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response?. Nat. Med. 12 (2006) 1005-1015
-
(2006)
Nat. Med.
, vol.12
, pp. 1005-1015
-
-
Wyss-Coray, T.1
-
67
-
-
34249055656
-
Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease
-
Zhang C., McNeil E., Dressler L., and Siman R. Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease. Exp. Neurol. (2006)
-
(2006)
Exp. Neurol.
-
-
Zhang, C.1
McNeil, E.2
Dressler, L.3
Siman, R.4
|