Specific spatial learning deficits become severe with age in β-amyloid precursor protein transgenic mice that harbor diffuse β-amyloid deposits but do not form plaques

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 25, 2001, Pages 14675-14680

  Koistinaho, Milla ^a,b   Ort, Michael ^a,c   Cimadevilla, Jose M ^a,d   Vondrous, Roman ^a   Cordell, Barbara ^e   Koistinaho, Jari ^b,f   Bures, Jan ^a   Higgins, Linda S ^e  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c CHARLES UNIVERSITY   (Czech Republic)

^d UNIVERSITY OF ALMERÍA   (Spain)

^e SCIOS INC   (United States)

^f KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

ADOLESCENT; AGE; AGED; ALZHEIMER DISEASE; AMNESIA; ANIMAL EXPERIMENT; ARTICLE; AVOIDANCE BEHAVIOR; DISEASE SEVERITY; ESCAPE BEHAVIOR; EXPLORATORY BEHAVIOR; HISTOPATHOLOGY; LATENT PERIOD; LEARNING DISORDER; MAZE TEST; MOUSE; NEUROFIBRILLARY TANGLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENILE PLAQUE; SPATIAL MEMORY; TRANSGENIC MOUSE;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; HUMANS; LEARNING; MALE; MAZE LEARNING; MICE; MICE, TRANSGENIC; SENILE PLAQUES; SPATIAL BEHAVIOR;

EID: 0035807829     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.261562998     Document Type: Article

References (54)