메뉴 건너뛰기




Volumn 169, Issue 2, 2006, Pages 544-552

Reduction of amyloid angiopathy and Aβ plaque burden after enriched housing in TgCRND8 mice: Involvement of multiple pathways

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; CHOLESTEROL; PROTEASOME;

EID: 33746633882     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2006.051107     Document Type: Article
Times cited : (74)

References (48)
  • 1
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson M: Pathways towards and away from Alzheimer's disease. Nature 2004, 430:631-639
    • (2004) Nature , vol.430 , pp. 631-639
    • Mattson, M.1
  • 2
    • 0345305683 scopus 로고    scopus 로고
    • Behavioral and psychological symptoms of dementia
    • Finkel SI: Behavioral and psychological symptoms of dementia. Clin Geriatr Med 2003, 19:799-824
    • (2003) Clin Geriatr Med , vol.19 , pp. 799-824
    • Finkel, S.I.1
  • 3
    • 0037202852 scopus 로고    scopus 로고
    • The dementias
    • Ritchie K, Lovestone S: The dementias. Lancet 2002, 360:1759-1766
    • (2002) Lancet , vol.360 , pp. 1759-1766
    • Ritchie, K.1    Lovestone, S.2
  • 7
    • 0037306414 scopus 로고    scopus 로고
    • Effects of different forms of environmental enrichment on behavioral, endocrinological, and immunological parameters in male mice
    • Marashi V, Barnekow A, Ossendorf E, Sachser N: Effects of different forms of environmental enrichment on behavioral, endocrinological, and immunological parameters in male mice. Horm Behav 2003, 43:281-292
    • (2003) Horm Behav , vol.43 , pp. 281-292
    • Marashi, V.1    Barnekow, A.2    Ossendorf, E.3    Sachser, N.4
  • 8
    • 0036139655 scopus 로고    scopus 로고
    • Neuronal plasticity and dendritic spines: Effect of environmental enrichment on intact and postischemic rat brain
    • Johansson BB, Belichenko PV: Neuronal plasticity and dendritic spines: effect of environmental enrichment on intact and postischemic rat brain. J Cereb Blood Flow Metab 2002, 22:89-96
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 89-96
    • Johansson, B.B.1    Belichenko, P.V.2
  • 9
    • 2942616850 scopus 로고    scopus 로고
    • Gene expression profiling in the intact and injured brain following environmental enrichment
    • Keyvani K, Sachser N, Witte OW, Paulus W: Gene expression profiling in the intact and injured brain following environmental enrichment. J Neuropathol Exp Neurol 2004, 63:598-609
    • (2004) J Neuropathol Exp Neurol , vol.63 , pp. 598-609
    • Keyvani, K.1    Sachser, N.2    Witte, O.W.3    Paulus, W.4
  • 12
    • 4043147336 scopus 로고    scopus 로고
    • Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition
    • Arendash G, Garcia M, Costa D, Cracchiolo J, Wefes I, Potter H: Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition. Neuroreport 2004, 15:1751-1754
    • (2004) Neuroreport , vol.15 , pp. 1751-1754
    • Arendash, G.1    Garcia, M.2    Costa, D.3    Cracchiolo, J.4    Wefes, I.5    Potter, H.6
  • 14
    • 0344305380 scopus 로고    scopus 로고
    • Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease
    • Jankowsky JL, Xu G, Fromholt D, Gonzales V, Borchelt DR: Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease. J Neuropathol Exp Neurol 2003, 62:1220-1227
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 1220-1227
    • Jankowsky, J.L.1    Xu, G.2    Fromholt, D.3    Gonzales, V.4    Borchelt, D.R.5
  • 16
    • 18244384051 scopus 로고    scopus 로고
    • Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease
    • Adlard PA, Perreau VM, Pop V, Cotman CW: Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. J Neurosci 2005, 25:4217-4221
    • (2005) J Neurosci , vol.25 , pp. 4217-4221
    • Adlard, P.A.1    Perreau, V.M.2    Pop, V.3    Cotman, C.W.4
  • 19
    • 0029665851 scopus 로고    scopus 로고
    • Electrophoretic separation of betaA4 peptides (1-40) and (1-42)
    • Klafki HW, Wiltfang J, Staufenbiel M: Electrophoretic separation of betaA4 peptides (1-40) and (1-42). Anal Biochem 1996, 237:24-29
    • (1996) Anal Biochem , vol.237 , pp. 24-29
    • Klafki, H.W.1    Wiltfang, J.2    Staufenbiel, M.3
  • 20
    • 0023472472 scopus 로고
    • Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
    • Schägger H, von Jagow G: Tricine-sodium dodecyl sulfate- polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 1987, 166:368-379
    • (1987) Anal Biochem , vol.166 , pp. 368-379
    • Schägger, H.1    Von Jagow, G.2
  • 21
    • 0038771172 scopus 로고    scopus 로고
    • Sex-specific difference in social support-a study in female guinea pigs
    • Kaiser S, Kirtzeck M, Hornschuh G, Sachser N: Sex-specific difference in social support-a study in female guinea pigs. Physiol Behav 79:297-303
    • Physiol Behav , vol.79 , pp. 297-303
    • Kaiser, S.1    Kirtzeck, M.2    Hornschuh, G.3    Sachser, N.4
  • 22
    • 0019784850 scopus 로고
    • F4/80, a monoclonal antibody directed specifically against the mouse macrophage
    • Austyn JM, Gordon S: F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur J Immunol 1981, 11:805-815
    • (1981) Eur J Immunol , vol.11 , pp. 805-815
    • Austyn, J.M.1    Gordon, S.2
  • 24
    • 17844375420 scopus 로고    scopus 로고
    • Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition
    • Yamamoto M, Horiba M, Buescher JL, Huang D, Gendelman HE, Ransohoff RM, Ikezu T: Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition. Am J Pathol 2005, 166:1475-1485
    • (2005) Am J Pathol , vol.166 , pp. 1475-1485
    • Yamamoto, M.1    Horiba, M.2    Buescher, J.L.3    Huang, D.4    Gendelman, H.E.5    Ransohoff, R.M.6    Ikezu, T.7
  • 25
    • 0242321274 scopus 로고    scopus 로고
    • EP2 and EP4 prostanoid receptor signaling
    • Regan JW: EP2 and EP4 prostanoid receptor signaling. Life Sci 2003, 74:143-153
    • (2003) Life Sci , vol.74 , pp. 143-153
    • Regan, J.W.1
  • 26
    • 2542421703 scopus 로고    scopus 로고
    • Neuronal expression of CD22: Novel mechanism for inhibiting microglial proinflammatory cytokine production
    • Mott RT, Ait-Ghezala G, Town T, Mori T, Vendrame M, Zeng J, Ehrhart J, Mullan M, Tan J: Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production. Glia 2004, 46:369-379
    • (2004) Glia , vol.46 , pp. 369-379
    • Mott, R.T.1    Ait-Ghezala, G.2    Town, T.3    Mori, T.4    Vendrame, M.5    Zeng, J.6    Ehrhart, J.7    Mullan, M.8    Tan, J.9
  • 27
    • 15044343929 scopus 로고    scopus 로고
    • Cytoplasmic protein tyrosine phosphatases, regulation and function: The roles of PTP1B and TC-PTP
    • Bourdeau A, Dube N, Tremblay ML: Cytoplasmic protein tyrosine phosphatases, regulation and function: the roles of PTP1B and TC-PTP. Curr Opin Cell Biol 2005, 17:203-209
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 203-209
    • Bourdeau, A.1    Dube, N.2    Tremblay, M.L.3
  • 28
    • 13844281550 scopus 로고    scopus 로고
    • How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: The role of microglia and astrocytes
    • Blasko I, Stampfer-Kountchev M, Robatscher P, Veerhuis R, Eikelenboom P, Grubeck-Loebenstein B: How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes. Aging Cell 2004, 3:169-176
    • (2004) Aging Cell , vol.3 , pp. 169-176
    • Blasko, I.1    Stampfer-Kountchev, M.2    Robatscher, P.3    Veerhuis, R.4    Eikelenboom, P.5    Grubeck-Loebenstein, B.6
  • 29
    • 17144380506 scopus 로고    scopus 로고
    • Microglia lacking e prostanoid receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity
    • Shie FS, Breyer RM, Montine TJ: Microglia lacking E prostanoid receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity. Am J Pathol 2005, 166:1163-1172
    • (2005) Am J Pathol , vol.166 , pp. 1163-1172
    • Shie, F.S.1    Breyer, R.M.2    Montine, T.J.3
  • 30
    • 17444410014 scopus 로고    scopus 로고
    • Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons
    • Shie FS, Montine KS, Breyer RM, Montine TJ: Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons. Brain Pathol 2005, 15:134-138
    • (2005) Brain Pathol , vol.15 , pp. 134-138
    • Shie, F.S.1    Montine, K.S.2    Breyer, R.M.3    Montine, T.J.4
  • 31
    • 0041672217 scopus 로고    scopus 로고
    • Regional effects of wheel running and environmental enrichment on cell genesis and microglia proliferation in the adult murine neocortex
    • Ehninger D, Kempermann G: Regional effects of wheel running and environmental enrichment on cell genesis and microglia proliferation in the adult murine neocortex. Cereb Cortex 2003, 13:845-851
    • (2003) Cereb Cortex , vol.13 , pp. 845-851
    • Ehninger, D.1    Kempermann, G.2
  • 33
    • 0035696328 scopus 로고    scopus 로고
    • Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice
    • DiCarlo G, Wilcock D, Henderson D, Gordon M, Morgan D: Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice. Neurobiol Aging 2001, 22:1007-1012
    • (2001) Neurobiol Aging , vol.22 , pp. 1007-1012
    • DiCarlo, G.1    Wilcock, D.2    Henderson, D.3    Gordon, M.4    Morgan, D.5
  • 34
    • 0035106780 scopus 로고    scopus 로고
    • Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
    • Bacskai BJ, Kajdasz ST, Christie RH, Carter C, Games D, Seubert P, Schenk D, Hyman BT: Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy. Nat Med 2001, 7:369-372
    • (2001) Nat Med , vol.7 , pp. 369-372
    • Bacskai, B.J.1    Kajdasz, S.T.2    Christie, R.H.3    Carter, C.4    Games, D.5    Seubert, P.6    Schenk, D.7    Hyman, B.T.8
  • 35
    • 32344440522 scopus 로고    scopus 로고
    • Bone marrow-derived mioroglia play a critical role in restricting senile plaque formation in Alzheimer's disease
    • Simard AR, Soulet D, Gowing G, Julien JP, Rivest S: Bone marrow-derived mioroglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 2006, 49:489-502
    • (2006) Neuron , vol.49 , pp. 489-502
    • Simard, A.R.1    Soulet, D.2    Gowing, G.3    Julien, J.P.4    Rivest, S.5
  • 36
    • 0036685522 scopus 로고    scopus 로고
    • Inflammation in neurodegenerative disease-a double-edged sword
    • Wyss-Coray T, Mucke L: Inflammation in neurodegenerative disease-a double-edged sword. Neuron 2002, 35:419-432
    • (2002) Neuron , vol.35 , pp. 419-432
    • Wyss-Coray, T.1    Mucke, L.2
  • 37
    • 0036849021 scopus 로고    scopus 로고
    • Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide
    • Rogers J, Strohmeyer R, Kovelowski CJ, Li R: Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide. Glia 2002, 40:260-269
    • (2002) Glia , vol.40 , pp. 260-269
    • Rogers, J.1    Strohmeyer, R.2    Kovelowski, C.J.3    Li, R.4
  • 38
    • 0141987860 scopus 로고    scopus 로고
    • The ubiquitin proteasome system in neurodegenerative diseases: Sometimes the chicken, sometimes the egg
    • Ciechanover A, Brundin P: The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. Neuron 2003, 40:427-446
    • (2003) Neuron , vol.40 , pp. 427-446
    • Ciechanover, A.1    Brundin, P.2
  • 39
    • 0034131044 scopus 로고    scopus 로고
    • Impaired proteasome function in Alzheimer's disease
    • Keller JN, Hanni KB, Markesbery WR: Impaired proteasome function in Alzheimer's disease. J Neurochem 2000, 75:436-439
    • (2000) J Neurochem , vol.75 , pp. 436-439
    • Keller, J.N.1    Hanni, K.B.2    Markesbery, W.R.3
  • 40
    • 0037383052 scopus 로고    scopus 로고
    • Relationship between beta-amyloid degradation and the 26S proteasome in neural cells
    • Lopez Salon M, Pasquini L, Besio Moreno M, Pasquini JM, Soto E: Relationship between beta-amyloid degradation and the 26S proteasome in neural cells. Exp Neurol 2003, 180:131-143
    • (2003) Exp Neurol , vol.180 , pp. 131-143
    • Lopez Salon, M.1    Pasquini, L.2    Besio Moreno, M.3    Pasquini, J.M.4    Soto, E.5
  • 42
    • 0345669752 scopus 로고    scopus 로고
    • Alzheimer's disease: The cholesterol connection
    • Puglielli L, Tanzi RE, Kovacs DM: Alzheimer's disease: the cholesterol connection. Nat Neurosci 2003, 6:345-351
    • (2003) Nat Neurosci , vol.6 , pp. 345-351
    • Puglielli, L.1    Tanzi, R.E.2    Kovacs, D.M.3
  • 47
    • 13544268809 scopus 로고    scopus 로고
    • Neurovascular mechanisms of Alzheimer's neurodegeneration
    • Zlokovic BV: Neurovascular mechanisms of Alzheimer's neurodegeneration. Trends Neurosci 2005, 28:202-208
    • (2005) Trends Neurosci , vol.28 , pp. 202-208
    • Zlokovic, B.V.1
  • 48
    • 27944461049 scopus 로고    scopus 로고
    • Sporadic cerebral amyloid angiopathy: Pathology, clinical implications, and possible pathomechanisms
    • Attems J: Sporadic cerebral amyloid angiopathy: pathology, clinical implications, and possible pathomechanisms. Acta Neuropathol (Berl) 2005, 110:345-359
    • (2005) Acta Neuropathol (Berl) , vol.110 , pp. 345-359
    • Attems, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.