Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress

Neuroscience

Volumn 127, Issue 3, 2004, Pages 601-609

  Dong, H ^a   Goico, B ^a   Martin, M ^a   Csernansky, C A ^b   Bertchume, A ^a   Csernansky, J G ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

amyloid plaques; 5 bromodeoxyuridine; AD; Alzheimer's disease; amyloid precursor protein; analysis of variance; ANOVA; APP; BrdU; cell proliferation; fluoxetine; GFAP; glial fibrillary acidic protein; hippocampus; isolation stress; NeuN; neurogenesis

Indexed keywords

AMYLOID; FLUOXETINE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; HIPPOCAMPUS; MALE; MEMORY; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; STRESS; TRANSGENIC MOUSE; WEANING;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOIDOSIS; ANIMALS; CELL DIVISION; DENTATE GYRUS; DISEASE MODELS, ANIMAL; FLUOXETINE; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; SEROTONIN UPTAKE INHIBITORS; SOCIAL ISOLATION; STRESS, PSYCHOLOGICAL;

EID: 3343015515     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.05.040     Document Type: Article

References (69)

1. Altman J. Are new neurons formed in the brains of adult mammals? Science. 135:1962;1127-1128
2. Altman J., Das G. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol. 124:1965;319-335
3. Alvarez-Buylla A., Nottebohm F. Migration of young neurons in adult avian brain. Nature. 335:1988;353-354
4. Bardgett M.E., Boeckman R., Krochmal D., Fernando H., Ahrens R., Csernansky J.G. NMDA receptor blockade and hippocampal neuronal loss impair fear conditioning and position habit reversal in C57Bl/6 mice. Brain Res Bull. 60:2003;131-142
5. Bartolomucci A., Palanza P., Sacerdote P., Ceresini G., Chirieleison A., Panerai A.E., Parmigiani S. Individual housing induces altered immuno-endocrine responses to psychological stress in male mice. Psychoneuroendocrinology. 28:2003;540-558
6. Bornemann K., Staufenbiel M. Transgenic mouse model of Alzheimer's disease. Ann NY Acad Sci. 908:2000;260-266
7. Cameron H., McKay R. Restoring production of hippocampal neurons in old age. Nat Neurosci. 2:1999;894-897
8. Cameron H.A., Woolley C.S., McEwwn B.S., Gould E. Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience. 56:1993;337-344
9. Cha J.H., Farrell L.A., Ahmed S.F., Fre A., Hsiao-Ashe K.K., Young A.B., Penney J.B., Locascio J.J., Hyman B.T., Irizarry M.C. Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein. Neurobiol Dis. 8:2001;90-102
10. Chapman P.F., White G.L., Jones M.W., Cooper-Blacketer D., Marshall V.J., Irizarry M., Younkin L., Good M.A., Bliss T.V., Hyman B.T., Younkin S.G., Hsiao K.K. Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat Neurosci. 2:1999;271-276
11. Cooper-Kuhn C.M., Kuhn H.G. Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain. Dev Brain Res. 134:2002;13-21
12. Csernansky J.G., Wang L., Joshi S., Miller J.P., Gado M., Kido D., McKeel D., Morris J.C., Miller M.I. Early DAT is distinguished from healthy aging by high dimensional mapping of the hippocampus. Neurology. 55:2000;1636-1643
13. Czeh B., Welt T., Fischer A.K., Erhardt A., Schmitt W., Muller M.B., Toschi N., Fuchs E., Keck M.E. Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation Effects on stress hormone levels and adult hippocampal neurogenesis. Biol Psychiatry. 52:2002;1057-1065
14. Eckert A., Oster M., Zerfass R., Hennerici M., Muller W.E. Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation. J Neurosci Res. 62:2001;183-192
15. Eriksson P.S., Perfilieva E., Bjork-Ericksson T., Alborn A.M., Nordborg C., Peterson D.A., Gage F.H. Neurogenesis in the adult human hippocampus. Nat Med. 4:1998;1313-1317
16. Feng R., Rampon C., Tang Y.P., Shrom D., Jin J., Kyin M., Langdon R.B., Sisodia S.S., Tsien J.Z. Deficient neurogenesis in the forebrain-specific presenilin-1 knockout mouse is associated with reduced clearance of hippocampal memory traces. Neuron. 32:2001;911-926
17. Franklin K., Paxinos G. The mouse brain in stereotaxic coordinates. 2nd ed:1997;Academic Press, Orlando, FL
18. Frautschy S., Yang F., Irrizarry M., Hyman B., Saido T.C., Hsiao K., Cole G.M. Microglial response to amyloid plaques in APPsw transgenic mice. Am J Pathol. 152:1998;307-317
19. Gage F.H. Mammalian neural stem cells. Science. 287:2000;1433-1438
20. Gage F.H. Neurogenesis in the adult brain. J Neurosci. 22:2002;612-613
21. Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature. 373:1995;523-527
22. Gould E., Beylin A., Tanapat P., Reeves A., Shors T.J. Hippocampal-dependent learning enhances the survival of granule neurons generated in the dentate gyrus of adult rats. Nat Neurosci. 2:1999;260-265
23. Gould E., Tanapat P., Rydel T., Nicholas H. Regulation of hippocampal neurogenesis in adulthood. Biol Psychiatry. 48:2000;715-720
24. Guntern E., Bouras C., Hoff P.R., Vallet P.G. An improved thioflavine S method for staining neurofibrillary tangles ad senile plaques in Alzheimer's disease. Experientia. 48:1992;8-10
25. Hanley T., Merlie J. Transgene detection in unpurified mouse tail DNA by polymerase chain reaction. Biotechniques. 10:1991;56
26. Harris-White M.E., Chu T. Estrogen (E2) and glucocorticoid (Gc) effects on microglia and Aβ clearance in vitro and in vivo. Neurochem Int. 39:2001;435-448
27. Haughey N.J., Nath A., Chan S.L., Borchard A.C., Rao M.S., Mattson M.P. Disruption of neurogenesis by amyloid β-peptide, and perturbed neural progenitor cell homeostasis, in model's of Alzheimer's disease. J Neurochem. 83:2002;1509-1524
28. Hayes N.L., Nowakowski R.S. Dynamics of cell proliferation in the adult dentate gyrus of two inbred strains of mice. Dev Brain Res. 143:2002;77-85
29. Holcomb L., Gordon M.N., McGowan E., Yu X., Benkovic S., Jantzen P., Wright K., Saad I., Mueller R., Morgan D., Sanders S., Zehr C., O'Campo K., Hardy J., Prada C.M., Eckman C., Younkin S., Hsiao K., Duff K. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med. 4:1998;97-100
30. Horner P., Gage F.H. Regeneration the damaged central nervous system. Nature. 407:2000;963-970
31. Hsiao K., Borchelt D.R., Olson K., Johannsdottir R., Kitt C., Yunis W., Xu S., Eckman C., Younkin S., Price D. Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins. Neuron. 15:1995;1-16
32. Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Aβ elevation and amyloid plaques in transgenic mice. Science. 274:1996;99-102
33. Hsiao K. Strain dependent and invariant features of transgenic mice expressing Alzheimer amyloid precursor protein. Prog Brain Res. 117:1998;335-341
34. Irizarry M., McNamara M., Fedorchak K., Hsiao K., Hyman B. APPsw transgenic mice develop age-related Ab deposits and neuropil abnormalities, but no neuronal loss in CA1. J Neuropathol Exp Neurol. 56:1997;965-973
35. Jack CR Jr, Peterson RC, Xu YC, Waring SC, O'Brien PC, Tangalos EG, Smith GE, Ivnik RJ, Kokmen (1997) Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology 49:786-794.
36. Jankowsky L., Xu G., Fromholt D., Gonzales V., Borchelt D. Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer's disease. J Neuropathol Exp Neurol. 62:2003;1220-1227
37. Jellinger K (1990) Morphology of Alzheimer's disease and related disorders. In: Alzheimer's disease, epidemiology, neurochemistry and clinics (Maurer K, Riederer P, Beckman H, eds), pp 61-77. New York, NY: Springer-Verlag.
38. Kaplan M., Hinds J. Neurogenesis in the adult rat Electron microscopic analysis of light radioautographs. Science. 197:1977;1092-1094
39. Kempermann G., Gage F.H. Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task. Eur J Neurosci. 16:2002;129-136
40. Kempermann G., Gast D., Kronenberg G., Yamaguchi M., Gage F.H. Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development. 130:2003;391-399
41. Kim J.J., Fanselow M.S. Modality-specific retrograde amnesia of fear. Science. 256:1992;675-677
42. Kornack D., Rakic P. Continuation of neurogenesis in the hippocampus of the adult macaque monkey. Proc Natl Acad Sci USA. 96:1999;5768-5773
43. Kotilinek L.A., Bacskai B., Westerman M., Kawarabayashi T., Younkin L., Hyman B.T., Ashe K.H. Reversible memory loss in a mouse transgenic model of Alzheimer's disease. J Neurosci. 22:2002;6331-6335
44. Laakso M.P., Soininen H., Partanen K., Helkala E.L., Hartikainen P., Vainio P., Hallikainen M., Hanninen T., Reikkinen P.J. Sr. Volumes of hippocampus, amygdala and frontal lobes in the MRI-based diagnosis of early Alzheimer's disease Correlation with memory functions. J Neural Trans. 9:1995;73-86
45. Lamb B.T., Bardel K.A., Kulnane L.S., Anderson J.J., Holtz G., Wagner S.L., Sisodia S.S., Hoeger E.J. Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice. Nat Neurosci. 2:1999;695-697
46. Lemaire V., Koehl M., Le Moal M., Abrous D.N. Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus. Proc Natl Acad Sci USA. 97:2000;11032-11037
47. Lois C., Alvarez-Buylla A. Long-distance neuronal migration in the adult mammalian brain. Science. 264:1994;1145-1148
48. Lupien S.J., Nair N.P., Briere S., Maheu F., Tu M.T., Lemay M., McEwen B.S., Meaney M.J. Increased cortisol levels and impaired cognition in human aging Implications for depression and dementia of later life. Rev Neurosci. 10:1999;117-139
49. Macklis J. New memories from new neurons. Nature. 410:2001;314-315. 317
50. Malberg J., Eisch A., Nestler E., Duman R. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci. 20:2000;9104-9110
51. Mattson M.P. Cellular actions of beta-amyloid precursor protein and its soluble fibrillogenic derivatives. Physiol Rev. 77:1997;1081-1132
52. McEwen B.S. The neurobiology of stress From serendipity to clinical relevance. Brain Res. 886:2000;172-189
53. Mirra S., Hart M., Terry R. Making the diagnosis of Alzheimer's disease A primer for practicing pathologists. Arch Pathol Lab Med. 117:1993;132-144
54. Moechars D., Lorent K., De Strooper B., Dewachter I., Van Leuve F. Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice. EMBO J. 15:1996;1265-1274
55. Murphy D.G., DeCarli C.S., Daly E., Gillette J.A., McIntosh A.R., Haxby J.V., Teichberg D., Schapiro M.B., Rapoport S.I., Horwitz B. Volumetric magnetic resonance imaging in men with dementia of the Alzheimer's type Correlations with disease severity. Biol Psychiatry. 34:1993;612-621
56. Price D. New perspectives on Alzheimer's disease. Annu Rev Neurosci. 9:1986;489-512
57. Prickaerts J., Koopmans G., Blokland A., Scheepens A. Learning and adult neurogenesis Survival with or without proliferation? Neurobiol Learn Mem. 81:2004;1-11
58. Quon D., Wang Y., Catalano R., Scardina J.M., Murakami K., Cordell B. Formation of beta-amyloid protein deposits in brains of transgenic mice. Nature. 352:1991;239-241
59. Selkoe D. Alzheimer's disease Genes, proteins, and therapy. Physiol Rev. 81:2001;741-766
60. Shimizu E., Tang Y.P., Rampon C., Tsien J.Z. NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation. Science. 290:2000;1170-1174
61. Shors T.J., Miesegaes G., Beylin A., Zhao M., Rydel T., Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature. 410:2001;372-375
62. Shors T.J., Townsend D.A., Zhao M., Kozorovitskiy Y., Gould E. Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus. 12:2002;578-584
63. Sturchler-Pierrat C., Abramowski D., Duke M., Widerhold K.H., Mistl C., Rothacher S., Ledermann B., Burki K., Frey P., Paganetti P.A., Waridel C., Calhoun M.E., Jucker M., Probst A., Staufenbiel M., Sommer B. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc Natl Acad Sci USA. 94:1997;13287-13292
64. Sun Y., Shan W., Guojun B., Onifade M.K., Patel S.N., LaDu M.J., Fagan A.M., Holtzman D.M. Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice Astrocyte-specific expression and differing biological effects of astrocyte-secreted apoe3 and apoe4 lipoproteins. J Neurosci. 18:1998;3261-3272
65. Van Dorpe J., Smeijers L., Dewachter I., Nuyens D., Spittaels K., Van Den Haute C., Mercken M., Moechars D., Laenen I., Kuiperi C., Bruynseels K., Tesseur I., Loos R., Vanderstichele H., Checler F., Sciot R., Van Leuven F. Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the London mutant of human APP in neurons. Am J Pathol. 157:2000;1283-1298
66. Van Praag H., Kempermann G., Gage F. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci. 2:1999;203-205
67. West M., Gundersen H. Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol. 296:1990;1-22
68. West M., Kawas C., Martin L., Troncoso J. The CA1 region of the human hippocampus is a hot spot in Alzheimer's disease. Ann NY Acad Sci. 908:2000;255-259
69. Winner B., Cooper-Kuhn C.M., Aigner R., Winkler J., Kuhn H.G. Long-term survival and cell death of newly generated neurons in the adult rat olfactory bulb. Eur J Neurosci. 16:2002;1681-1689