Progressive Cognitive Impairment and Anxiety Induction in the Absence of Plaque Deposition in C57BL/6 Inbred Mice Expressing Transgenic Amyloid Precursor Protein

Journal of Neuroscience Research

Volumn 76, Issue 4, 2004, Pages 572-580

  Lee, Kang Woo ^a,b   Lee, Si Hyoung ^a   Kim, Hyuck ^a   Song, Jin Sook ^c   Yang, Sung Don ^c   Paik, Sang Gi ^b   Han, Pyung Lim ^a  

^a Ewha Womans University School of Medicine   (South Korea)

^b Chungnam National University   (South Korea)

^c Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

AD model; Anxiety; Cognitive deficits; Transgenic mouse

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CALBINDIN; PROTEIN C FOS;

ALZHEIMER DISEASE; AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; BEHAVIOR; COGNITIVE DEFECT; CONTROLLED STUDY; DNA MICROARRAY; GENE MUTATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; LEARNING; MEMORY DISORDER; MOTOR COORDINATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENILE PLAQUE; TRANSGENE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANALYSIS OF VARIANCE; ANIMALS; ANXIETY; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BLOTTING, NORTHERN; BLOTTING, WESTERN; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOHISTOCHEMISTRY; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PSYCHOMOTOR PERFORMANCE; REACTION TIME; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 2342572400     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20127     Document Type: Article

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