Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19(INK4d)

Nature

Volumn 395, Issue 6699, 1998, Pages 244-250

  Brotherton, Deborah H ^a   Dhanaraj, Venugopal ^a   Wick, Scott ^b   Brizuela, Leonardo ^b   Domaille, Peter J ^c   Volyanik, Elena ^a   Xu, Xu ^b   Parisini, Emilio ^a   Smith, Brian O ^a   Archer, Sharon J ^c   Serrano, Manuel ^d   Brenner, Stephen L ^c   Blundell, Tom L ^a   Laue, Ernest D ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b GPC Biotech Inc   (United States)

^c DUPONT COMPANY   (United States)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CARRIER PROTEINS; CATALYSIS; CELL CYCLE PROTEINS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P19; CYCLIN-DEPENDENT KINASES; ESCHERICHIA COLI; HUMANS; INSECTS; MICE; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0032541640     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/26164     Document Type: Article

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