A key role for caspase-2 and caspase-3 in the apoptosis induced by 2-chloro-2′-deoxy-adenosine (Cladribine) and 2-chloro-adenosine in human astrocytoma cells

Molecular Pharmacology

Volumn 63, Issue 6, 2003, Pages 1437-1447

  Ceruti, Stefania ^a   Beltrami, Elena ^a   Matarrese, Paola ^b   Mazzola, Alessia ^a   Cattabeni, Flaminio ^a   Malorni, Walter ^b   Abbracchio, Maria P ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLOROADENOSINE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BETULIC ACID; CASPASE 2; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CLADRIBINE; CYTOCHROME C; DEOXYRIBOSE; ETOPOSIDE; N BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; N BENZYLOXYCARBONYLVALYLASPARTYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; SODIUM CYANATE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTOMA; CELL DEATH; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; TIME SERIES ANALYSIS; TUMOR CELL LINE;

2-CHLOROADENOSINE; ANTINEOPLASTIC AGENTS; APOPTOSIS; ASTROCYTOMA; CASPASE 2; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CLADRIBINE; CYTOCHROME C GROUP; ENZYME ACTIVATION; HUMANS; MITOCHONDRIA; TUMOR CELLS, CULTURED;

EID: 0038576220     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.63.6.1437     Document Type: Article

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