Intracellular kinase inhibitors selected from combinatorial libraries of designed ankyrin repeat proteins

Journal of Biological Chemistry

Volumn 280, Issue 26, 2005, Pages 24715-24722

  Amstutz, Patrick ^a   Binz, H Kaspar ^a   Parizek, Petra ^a   Stumpp, Michael T ^a   Kohl, Andreas ^a   Grütter, Markus G ^a   Forrer, Patrik ^a   Plückthun, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BACTERIA; ENZYME INHIBITION; GENETIC ENGINEERING; PATHOLOGY;

ANKYRIN; CELLULAR CONTEXTS; INTRACELLULAR KINASE INHIBITORS; PROTEIN FUNCTIONS;

ENZYMES;

AMINOGLYCOSIDE 3' PHOSPHOTRANSFERASE IIIA; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANKYRIN; PHOSPHOTRANSFERASE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM; BINDING AFFINITY; COMBINATORIAL LIBRARY; CONTROLLED STUDY; ENZYME INHIBITION; EUKARYOTE; HUMAN; HUMAN CELL; IN VITRO STUDY; KNOCKOUT GENE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE;

AMIKACIN; AMINOGLYCOSIDES; ANKYRINS; ANTI-BACTERIAL AGENTS; BIOTINYLATION; CATALYTIC DOMAIN; CHROMATOGRAPHY; CLONING, MOLECULAR; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE LIBRARY; KANAMYCIN; KANAMYCIN KINASE; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; PHENOTYPE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBOSOMES; SENSITIVITY AND SPECIFICITY; SURFACE PLASMON RESONANCE;

EUKARYOTA;

EID: 21744440783     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501746200     Document Type: Article

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