Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors

Genes and Development

Volumn 14, Issue 24, 2000, Pages 3115-3125

  Jeffrey, Philip D ^a   Tong, Lily ^a,b   Pavletich, Nikola P ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Schering Plough Institute   (United States)

Author keywords

CDK inhibition; Cdk6; Cell cycle; INK4; Viral cyclin

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; INK4 INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME SPECIFICITY; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; BINDING SITES; CARRIER PROTEINS; CATALYTIC DOMAIN; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P18; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; TUMOR SUPPRESSOR PROTEINS;

EID: 0034671563     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.851100     Document Type: Article

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