메뉴 건너뛰기




Volumn 26, Issue 1, 2007, Pages 25-37

Molecular genetics of prostate cancer: Clinical translational opportunities

Author keywords

LOH; Molecular alterations; Prostate cancer

Indexed keywords

2 METHYLACYL COENZYME A RACEMASE; ACETYLSALICYLIC ACID; BRCA2 PROTEIN; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2B; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FATTY ACID SYNTHASE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 90; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTATE SPECIFIC ANTIGEN; PROTEIN BCL 2; PROTEIN P16INK4A; PROTEIN P53; RAF PROTEIN; SOMATOMEDIN; TELOMERASE; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TUMOR MARKER;

EID: 34247495122     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (8)

References (171)
  • 1
    • 0037426058 scopus 로고    scopus 로고
    • Prostate cancer epidemiology
    • Gronberg H.: Prostate cancer epidemiology. Lancet 361:859-864, 2003.
    • (2003) Lancet , vol.361 , pp. 859-864
    • Gronberg, H.1
  • 3
    • 0037444031 scopus 로고    scopus 로고
    • Pathological and molecular aspects of prostate cancer
    • De Marzo A.M., Nelson W.G., Isaacs W.B., Epstein J.I.: Pathological and molecular aspects of prostate cancer. Lancet 361:955-964, 2003.
    • (2003) Lancet , vol.361 , pp. 955-964
    • De Marzo, A.M.1    Nelson, W.G.2    Isaacs, W.B.3    Epstein, J.I.4
  • 4
    • 33144487134 scopus 로고    scopus 로고
    • Genomics of prostate cancer: Is there anything to "translate"α
    • Kopper L., Timar J.: Genomics of prostate cancer: is there anything to "translate"α Pathol. Oncol. Res. 11:197-203, 2005.
    • (2005) Pathol. Oncol. Res , vol.11 , pp. 197-203
    • Kopper, L.1    Timar, J.2
  • 5
    • 29844443964 scopus 로고    scopus 로고
    • Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies
    • Mimeault M., Batra S.K. Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies. Carcinogenesis 27:1-22, 2006.
    • (2006) Carcinogenesis , vol.27 , pp. 1-22
    • Mimeault, M.1    Batra, S.K.2
  • 6
    • 0037364371 scopus 로고    scopus 로고
    • Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma
    • Harden S.V., Guo Z., Epstein J.I., Sidransky D.: Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma. J. Urol. 169:1138-1142, 2003.
    • (2003) J. Urol , vol.169 , pp. 1138-1142
    • Harden, S.V.1    Guo, Z.2    Epstein, J.I.3    Sidransky, D.4
  • 7
    • 34247540779 scopus 로고    scopus 로고
    • Preoperative serum DNA GSTP1 CpG island hypermethylation and the risk of early prostate-specific antigen recurrence following radical prostatectomy
    • Bastian P.J., Palapattu G.S., Lin X. et al: Preoperative serum DNA GSTP1 CpG island hypermethylation and the risk of early prostate-specific antigen recurrence following radical prostatectomy. Cancer Res. 65:4762-8, 2005.
    • (2005) Cancer Res , vol.65 , pp. 4762-4768
    • Bastian, P.J.1    Palapattu, G.S.2    Lin, X.3
  • 8
    • 19944398464 scopus 로고    scopus 로고
    • High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB
    • Van de Sande T., Roskams T., Lerut E. et al: High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB. J. Pathol. 206:214-219, 2005.
    • (2005) J. Pathol , vol.206 , pp. 214-219
    • Van de Sande, T.1    Roskams, T.2    Lerut, E.3
  • 9
    • 25444518998 scopus 로고    scopus 로고
    • A Variant of the alpha-methyl-acyl-CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer
    • Mubiru J.N., Valente A.J., Troyer D.A.: A Variant of the alpha-methyl-acyl-CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer. Prostate 65:117-123, 2005.
    • (2005) Prostate , vol.65 , pp. 117-123
    • Mubiru, J.N.1    Valente, A.J.2    Troyer, D.A.3
  • 10
    • 0034662631 scopus 로고    scopus 로고
    • The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators
    • Gayther S.A., de Foy K.A., Harrington P. et al: The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators. Cancer Res. 60:4513-4518, 2000.
    • (2000) Cancer Res , vol.60 , pp. 4513-4518
    • Gayther, S.A.1    de Foy, K.A.2    Harrington, P.3
  • 11
    • 0037222306 scopus 로고    scopus 로고
    • Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene
    • Edwards S.M., Kote-Jarai Z., Meitz J. et al: Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene. Am. J. Hum. Genet. 72:1-12, 2003.
    • (2003) Am. J. Hum. Genet , vol.72 , pp. 1-12
    • Edwards, S.M.1    Kote-Jarai, Z.2    Meitz, J.3
  • 12
    • 1442307845 scopus 로고    scopus 로고
    • Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2
    • Liede A., Karlan B.Y., Narod S.A.: Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2. J. Clin. Oncol. 22:735-742, 2004.
    • (2004) J. Clin. Oncol , vol.22 , pp. 735-742
    • Liede, A.1    Karlan, B.Y.2    Narod, S.A.3
  • 13
    • 0000009909 scopus 로고    scopus 로고
    • Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search
    • Smith J.R., Freije D., Carpten J.D. et al: Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. Science 274:1371-1374, 1996.
    • (1996) Science , vol.274 , pp. 1371-1374
    • Smith, J.R.1    Freije, D.2    Carpten, J.D.3
  • 14
    • 0035135523 scopus 로고    scopus 로고
    • A candidate prostate cancer susceptibility gene at chromosome 17p
    • Tavtigian S.V., Simard J., Teng D.H. et al: A candidate prostate cancer susceptibility gene at chromosome 17p. Nat Genet. 27:172-180, 2001.
    • (2001) Nat Genet , vol.27 , pp. 172-180
    • Tavtigian, S.V.1    Simard, J.2    Teng, D.H.3
  • 15
    • 20144389308 scopus 로고    scopus 로고
    • Association of susceptibility alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with prostate cancer severity in European American and African American men
    • Rennert H., Zeigler-Johnson C.M., Addya K. et al: Association of susceptibility alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with prostate cancer severity in European American and African American men. Cancer Epidemiol. Biomarkers Prev. 14:949-957, 2005.
    • (2005) Cancer Epidemiol. Biomarkers Prev , vol.14 , pp. 949-957
    • Rennert, H.1    Zeigler-Johnson, C.M.2    Addya, K.3
  • 16
    • 18544377048 scopus 로고    scopus 로고
    • Germline mutations in the ribonuclease L gene in families showing linkage with HPC1
    • Carpten J., Nupponen N., Issacs S. et al.: Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat. Genet. 30:181-184, 2002.
    • (2002) Nat. Genet , vol.30 , pp. 181-184
    • Carpten, J.1    Nupponen, N.2    Issacs, S.3
  • 17
    • 18644386765 scopus 로고    scopus 로고
    • Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk
    • Xu J., Zheng S.L., Komiya A. et al: Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat. Genet. 32: 321-325, 2002.
    • (2002) Nat. Genet , vol.32 , pp. 321-325
    • Xu, J.1    Zheng, S.L.2    Komiya, A.3
  • 18
    • 0037431434 scopus 로고    scopus 로고
    • The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the gamma-tubulin complex
    • Korver W., Guevara C., Chen Y. et al: The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the gamma-tubulin complex. Int. J. Cancer 104: 283-288, 2003.
    • (2003) Int. J. Cancer , vol.104 , pp. 283-288
    • Korver, W.1    Guevara, C.2    Chen, Y.3
  • 19
    • 0035393631 scopus 로고    scopus 로고
    • Polymorphisms in the prostate cancer susceptibility gene HPC2/ELAC2 in multiplex families and healthy controls
    • Suarez B.K., Gerhard D.S., Lin J. et al: Polymorphisms in the prostate cancer susceptibility gene HPC2/ELAC2 in multiplex families and healthy controls. Cancer Res. 61:4982-4984, 2001.
    • (2001) Cancer Res , vol.61 , pp. 4982-4984
    • Suarez, B.K.1    Gerhard, D.S.2    Lin, J.3
  • 20
    • 0035882035 scopus 로고    scopus 로고
    • ELAC2/HPC2 involvement in hereditary and sporadic prostate cancer
    • Rokman A., Ikonen T., Mononen N. et al: ELAC2/HPC2 involvement in hereditary and sporadic prostate cancer. Cancer Res. 61:6038-6041, 2001.
    • (2001) Cancer Res , vol.61 , pp. 6038-6041
    • Rokman, A.1    Ikonen, T.2    Mononen, N.3
  • 21
    • 0035420191 scopus 로고    scopus 로고
    • Role of HPC2/ELAC2 in hereditary prostate cancer
    • Wang L., McDonnell S.K., Elkins D.A. et al: Role of HPC2/ELAC2 in hereditary prostate cancer. Cancer Res. 61:6494-6499, 2001.
    • (2001) Cancer Res , vol.61 , pp. 6494-6499
    • Wang, L.1    McDonnell, S.K.2    Elkins, D.A.3
  • 22
    • 0032805744 scopus 로고    scopus 로고
    • Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis
    • De Marzo A.M., Marchi V.L., Epstein J.I., Nelson W.G.: Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis. Am. J. Pathol. 155:1985-1992, 1999.
    • (1999) Am. J. Pathol , vol.155 , pp. 1985-1992
    • De Marzo, A.M.1    Marchi, V.L.2    Epstein, J.I.3    Nelson, W.G.4
  • 24
    • 19044373249 scopus 로고    scopus 로고
    • A novel founder mutation in the RNASEL gene, 471delAAAG, is associated with prostate cancer in Ashkenazi Jews
    • Rennert H, Bercovich D, Hubert A. et al: A novel founder mutation in the RNASEL gene, 471delAAAG, is associated with prostate cancer in Ashkenazi Jews. Am. J. Hum. Genet. 71:981-984, 2002.
    • (2002) Am. J. Hum. Genet , vol.71 , pp. 981-984
    • Rennert, H.1    Bercovich, D.2    Hubert, A.3
  • 25
    • 18344385832 scopus 로고    scopus 로고
    • Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer
    • Rokman A., Ikonen T., Seppala E.H. et al: Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer. Am. J. Hum. Genet. 70:1299-1304, 2002.
    • (2002) Am. J. Hum. Genet , vol.70 , pp. 1299-1304
    • Rokman, A.1    Ikonen, T.2    Seppala, E.H.3
  • 26
    • 0026553251 scopus 로고
    • 5-alpha-reductase activity and risk of prostate cancer among Japanese and US white and black males
    • Ross R.K., Bernstein L., Lobo R.A. et al: 5-alpha-reductase activity and risk of prostate cancer among Japanese and US white and black males. Lancet 339:887-889, 1992.
    • (1992) Lancet , vol.339 , pp. 887-889
    • Ross, R.K.1    Bernstein, L.2    Lobo, R.A.3
  • 27
  • 28
    • 0033581453 scopus 로고    scopus 로고
    • Association of missense substitution in SRD5A2 gene with prostate cancer in African-American and Hispanic men in Los Angeles, USA
    • Makridakis N.M., Ross R.K., Pike M.C.: Association of missense substitution in SRD5A2 gene with prostate cancer in African-American and Hispanic men in Los Angeles, USA. Lancet 354: 975-978, 1999.
    • (1999) Lancet , vol.354 , pp. 975-978
    • Makridakis, N.M.1    Ross, R.K.2    Pike, M.C.3
  • 29
    • 0032846313 scopus 로고    scopus 로고
    • Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2)
    • Lunn R.M., Bell D.A., Mohler J.L., Taylor J.A.: Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2). Carcinogenesis. 20:1727-1731, 1999.
    • (1999) Carcinogenesis , vol.20 , pp. 1727-1731
    • Lunn, R.M.1    Bell, D.A.2    Mohler, J.L.3    Taylor, J.A.4
  • 30
    • 0034238111 scopus 로고    scopus 로고
    • A polymorphism in the CYP17 gene is associated with prostate cancer risk
    • Gsur A., Bernhofer G., Hinteregger S. et al: A polymorphism in the CYP17 gene is associated with prostate cancer risk. Int. J. Cancer 87:434-437, 2000.
    • (2000) Int. J. Cancer , vol.87 , pp. 434-437
    • Gsur, A.1    Bernhofer, G.2    Hinteregger, S.3
  • 31
    • 0035371666 scopus 로고    scopus 로고
    • Impact of genetic polymorphisms of 17-hydroxylase cytochrome P-450 (CYP17) and steroid 5alpha-reductase type II (SRD5A2) genes on prostate-cancer risk among the Japanese population
    • Yamada Y., Watanabe M., Murata M. et al: Impact of genetic polymorphisms of 17-hydroxylase cytochrome P-450 (CYP17) and steroid 5alpha-reductase type II (SRD5A2) genes on prostate-cancer risk among the Japanese population. Int. J. Cancer. 92:683-686, 2001.
    • (2001) Int. J. Cancer , vol.92 , pp. 683-686
    • Yamada, Y.1    Watanabe, M.2    Murata, M.3
  • 32
    • 0028243778 scopus 로고
    • Allelic loss in locally metastatic, multi sampled prostate cancer
    • Sakr W.A., Macoska J.A., Benson P. et al: Allelic loss in locally metastatic, multi sampled prostate cancer. Cancer Res. 54:3273-3277, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3273-3277
    • Sakr, W.A.1    Macoska, J.A.2    Benson, P.3
  • 33
    • 0028849282 scopus 로고
    • Chromosomal anomalies in prostatic intraepithelial neoplasia and carcinoma detected by fluorescence in situ hybridization
    • Qian J., Bostwick D.G., Takahashi S. et al: Chromosomal anomalies in prostatic intraepithelial neoplasia and carcinoma detected by fluorescence in situ hybridization. Cancer Res. 55:5408-5414, 1995.
    • (1995) Cancer Res , vol.55 , pp. 5408-5414
    • Qian, J.1    Bostwick, D.G.2    Takahashi, S.3
  • 34
    • 0343416808 scopus 로고    scopus 로고
    • Allelic loss of 8p sequences in prostatic intraepithelial neoplasia and carcinoma
    • Haggman M.J., Wojno K.J., Pearsall C.P., Macoska J.A.: Allelic loss of 8p sequences in prostatic intraepithelial neoplasia and carcinoma. Urology 50:643-647, 1997b.
    • (1997) Urology , vol.50 , pp. 643-647
    • Haggman, M.J.1    Wojno, K.J.2    Pearsall, C.P.3    Macoska, J.A.4
  • 35
    • 0026016492 scopus 로고
    • Phenotypic relationships of prostatic intraepithelial neoplasia to invasive prostatic carcinoma
    • Nagle R.B., Brawer M.K., Kittelson J., Clark V.: Phenotypic relationships of prostatic intraepithelial neoplasia to invasive prostatic carcinoma. Am. J. Pathol. 138: 119-128, 1991.
    • (1991) Am. J. Pathol , vol.138 , pp. 119-128
    • Nagle, R.B.1    Brawer, M.K.2    Kittelson, J.3    Clark, V.4
  • 36
    • 0342276104 scopus 로고    scopus 로고
    • The relationship between prostatic intraepithelial neoplasia and prostate cancer: Critical issues
    • Haggman M.J., Macoska J.A., Wojno K.J., Oesterling J.E.: The relationship between prostatic intraepithelial neoplasia and prostate cancer: Critical issues. J. Urol. 158:12-22, 1997a.
    • (1997) J. Urol , vol.158 , pp. 12-22
    • Haggman, M.J.1    Macoska, J.A.2    Wojno, K.J.3    Oesterling, J.E.4
  • 37
    • 0028364668 scopus 로고
    • Deletion mapping of chromosome 8p in colorectal carcinoma and dysplasia arising in ulcerative colitis, prostatic carcinoma, and malignant fibrous histiocytomas
    • Chang M., Tsuchiya K., Batchelor R.H. et al: Deletion mapping of chromosome 8p in colorectal carcinoma and dysplasia arising in ulcerative colitis, prostatic carcinoma, and malignant fibrous histiocytomas. Am. J. Pathol. 144: 1-6, 1994.
    • (1994) Am. J. Pathol , vol.144 , pp. 1-6
    • Chang, M.1    Tsuchiya, K.2    Batchelor, R.H.3
  • 38
    • 0028059899 scopus 로고
    • Deletion mapping of chromosome 8p in prostate cancer by fluorescence in situ hybridization
    • Matsuyama H., Pan Y., Skoog L. et al: Deletion mapping of chromosome 8p in prostate cancer by fluorescence in situ hybridization. Oncogene 9: 3071-3076, 1994.
    • (1994) Oncogene , vol.9 , pp. 3071-3076
    • Matsuyama, H.1    Pan, Y.2    Skoog, L.3
  • 39
    • 0028793873 scopus 로고
    • Evidence for three tumor suppressor gene loci on chromosome 8p in human prostate cancer
    • Macoska J.A., Trybus T.M., Benson P.D. et al: Evidence for three tumor suppressor gene loci on chromosome 8p in human prostate cancer. Cancer Res. 55: 5390-5395, 1995.
    • (1995) Cancer Res , vol.55 , pp. 5390-5395
    • Macoska, J.A.1    Trybus, T.M.2    Benson, P.D.3
  • 40
    • 9344222738 scopus 로고    scopus 로고
    • Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21
    • Vocke C.D., Pozzatti R.O., Bostwick D.G. et al: Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21. Cancer Res. 56:2411-2416, 1996.
    • (1996) Cancer Res , vol.56 , pp. 2411-2416
    • Vocke, C.D.1    Pozzatti, R.O.2    Bostwick, D.G.3
  • 41
    • 0034181844 scopus 로고    scopus 로고
    • 8p22 loss concurrent with 8c gain is associated with poor outcome in prostate cancer
    • Macoska J.A., Trybus T.M., Wojno K.J.: 8p22 loss concurrent with 8c gain is associated with poor outcome in prostate cancer. Urology 55:776-782, 2000.
    • (2000) Urology , vol.55 , pp. 776-782
    • Macoska, J.A.1    Trybus, T.M.2    Wojno, K.J.3
  • 42
    • 26944453121 scopus 로고    scopus 로고
    • High-resolution array comparative genomic hybridization of chromosome arm 8q: Evaluation of genetic progression markers for prostate cancer
    • van Duin M., van Marion R., Vissers K. et al: High-resolution array comparative genomic hybridization of chromosome arm 8q: Evaluation of genetic progression markers for prostate cancer. Genes Chromosomes Cancer 44:438-449, 2005.
    • (2005) Genes Chromosomes Cancer , vol.44 , pp. 438-449
    • van Duin, M.1    van Marion, R.2    Vissers, K.3
  • 43
    • 0031397328 scopus 로고    scopus 로고
    • Tumour-suppressor genes in prostatic oncogenesis: A positional approach
    • Bookstein R., Bova G.S., MacGrogan D., Levy A., Isaacs W.B.: Tumour-suppressor genes in prostatic oncogenesis: a positional approach. Br. J. Urol. 79:28-36, 1997.
    • (1997) Br. J. Urol , vol.79 , pp. 28-36
    • Bookstein, R.1    Bova, G.S.2    MacGrogan, D.3    Levy, A.4    Isaacs, W.B.5
  • 44
    • 0035849791 scopus 로고    scopus 로고
    • Functional identification of LZTS1 as a candidate prostate tumor suppressor gene on human chromosome 8p22
    • Cabeza-Arvelaiz Y., Sepulveda J.L., Lebovitz R.M., Thompson T.C., Chinault A.C.: Functional identification of LZTS1 as a candidate prostate tumor suppressor gene on human chromosome 8p22. Oncogene 20:4169-4179, 2001.
    • (2001) Oncogene , vol.20 , pp. 4169-4179
    • Cabeza-Arvelaiz, Y.1    Sepulveda, J.L.2    Lebovitz, R.M.3    Thompson, T.C.4    Chinault, A.C.5
  • 45
    • 0038207967 scopus 로고    scopus 로고
    • Haploinsufficiency and reduced expression of genes localized to the 8p chromosomal region in human prostate tumors
    • Chaib H., MacDonald J.W., Vessella R.L. et al: Haploinsufficiency and reduced expression of genes localized to the 8p chromosomal region in human prostate tumors. Genes Chromosomes Cancer 37:306-313, 2003.
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 306-313
    • Chaib, H.1    MacDonald, J.W.2    Vessella, R.L.3
  • 46
    • 0031194107 scopus 로고    scopus 로고
    • A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer
    • He W.W., Sciavolino P.J., Wing J.: A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer. Genomics 43:69-77, 1997.
    • (1997) Genomics , vol.43 , pp. 69-77
    • He, W.W.1    Sciavolino, P.J.2    Wing, J.3
  • 47
    • 0030822020 scopus 로고    scopus 로고
    • Coding region of NKX3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers
    • Voeller H.J., Augustus M., Madike V., Bova G.S., Carter K.C., Gelmann E.P.: Coding region of NKX3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers. Cancer Res. 57:4455-4459, 1997.
    • (1997) Cancer Res , vol.57 , pp. 4455-4459
    • Voeller, H.J.1    Augustus, M.2    Madike, V.3    Bova, G.S.4    Carter, K.C.5    Gelmann, E.P.6
  • 48
    • 0033561173 scopus 로고    scopus 로고
    • Roles for Nkx3.1 in prostate development and cancer
    • Bhatia-Gaur R., Donjacour A.A., Sciavolino P.J. et al: Roles for Nkx3.1 in prostate development and cancer. Genes & Dev. 13: 966-977, 1999.
    • (1999) Genes & Dev , vol.13 , pp. 966-977
    • Bhatia-Gaur, R.1    Donjacour, A.A.2    Sciavolino, P.J.3
  • 49
    • 0034307013 scopus 로고    scopus 로고
    • Molecular genetics of prostate cancer
    • Abate-Shen C., Shen M.M.: Molecular genetics of prostate cancer. Genes & Dev. 14:2410-2434, 2000.
    • (2000) Genes & Dev , vol.14 , pp. 2410-2434
    • Abate-Shen, C.1    Shen, M.M.2
  • 50
    • 0029997010 scopus 로고    scopus 로고
    • Genetic alterations in untreated metastases and androgen independent prostate cancer detected by comparative genomic hybridization and allelotyping
    • Cher M.L., Bova G.S., Moore D.H. et al: Genetic alterations in untreated metastases and androgen independent prostate cancer detected by comparative genomic hybridization and allelotyping. Cancer Res. 56:3091-3102, 1996.
    • (1996) Cancer Res , vol.56 , pp. 3091-3102
    • Cher, M.L.1    Bova, G.S.2    Moore, D.H.3
  • 51
    • 0030844906 scopus 로고    scopus 로고
    • Allelic loss on chromosome 13q in human prostate carcinoma
    • Melamed J., Einhorn J.M., Ittmann M.M. Allelic loss on chromosome 13q in human prostate carcinoma. Clin. Cancer Res. 3:1867-1872, 1997.
    • (1997) Clin. Cancer Res , vol.3 , pp. 1867-1872
    • Melamed, J.1    Einhorn, J.M.2    Ittmann, M.M.3
  • 52
    • 0032535003 scopus 로고    scopus 로고
    • Identification of 12p as a region of frequent deletion in advanced prostate cancer
    • Kibel A. S., Schutte M., Kern S. E., Isaacs W. B., Bova G. S.: Identification of 12p as a region of frequent deletion in advanced prostate cancer. Cancer Res. 58:5652-5655, 1998.
    • (1998) Cancer Res , vol.58 , pp. 5652-5655
    • Kibel, A.S.1    Schutte, M.2    Kern, S.E.3    Isaacs, W.B.4    Bova, G.S.5
  • 54
    • 0032963644 scopus 로고    scopus 로고
    • Genetic pattern of prostate cancer progression
    • Saric T., Brkanac Z., Troyer D.A. et al: Genetic pattern of prostate cancer progression. Int. J. Cancer 81: 219-224, 1999.
    • (1999) Int. J. Cancer , vol.81 , pp. 219-224
    • Saric, T.1    Brkanac, Z.2    Troyer, D.A.3
  • 55
    • 0032767783 scopus 로고    scopus 로고
    • Chromosomal basis of adenocarcinoma of the prostate
    • Verma R.S., Manikal M., Conte R.A., Godec C.J.: Chromosomal basis of adenocarcinoma of the prostate. Cancer Invest. 17: 441-447, 1999.
    • (1999) Cancer Invest , vol.17 , pp. 441-447
    • Verma, R.S.1    Manikal, M.2    Conte, R.A.3    Godec, C.J.4
  • 56
    • 12444265384 scopus 로고    scopus 로고
    • Genetic evaluation of localized prostate cancer in a cohort of forty patients: Gain of distal 8q discriminates between progressors and non-progressors
    • van Dekken H., Alers J.C., Damen I.A. et al: Genetic evaluation of localized prostate cancer in a cohort of forty patients: gain of distal 8q discriminates between progressors and non-progressors. Lab. Invest. 83:789-796, 2003.
    • (2003) Lab. Invest , vol.83 , pp. 789-796
    • van Dekken, H.1    Alers, J.C.2    Damen, I.A.3
  • 57
    • 0034656678 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization evaluation of c-myc and androgen receptor gene amplification and chromosomal anomalies in prostate cancer in Japanese patients
    • Miyoshi Y., Uemura H., Fujinami K. et al: Fluorescence in situ hybridization evaluation of c-myc and androgen receptor gene amplification and chromosomal anomalies in prostate cancer in Japanese patients. Prostate 43:225-232, 2000.
    • (2000) Prostate , vol.43 , pp. 225-232
    • Miyoshi, Y.1    Uemura, H.2    Fujinami, K.3
  • 58
    • 0025223062 scopus 로고
    • Allelic loss of chromosomes 16q and 10q in human prostate cancer
    • Carter B.S., Ewing C.M., Ward W.S. et al: Allelic loss of chromosomes 16q and 10q in human prostate cancer. Proc. Natl. Acad. Sci. 87: 8751-8755, 1990b.
    • (1990) Proc. Natl. Acad. Sci , vol.87 , pp. 8751-8755
    • Carter, B.S.1    Ewing, C.M.2    Ward, W.S.3
  • 60
    • 0029877213 scopus 로고    scopus 로고
    • Allelic loss on chromosome 10 in prostate adenocarcinoma
    • Ittmann M.M.: Allelic loss on chromosome 10 in prostate adenocarcinoma. Cancer Res. 56: 2143-2147, 1996.
    • (1996) Cancer Res , vol.56 , pp. 2143-2147
    • Ittmann, M.M.1
  • 61
    • 0029975245 scopus 로고    scopus 로고
    • Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer
    • Trybus T.M., Burgess A.C., Wojno K.J., Glover T.W., Macoska J.A. Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer. Cancer Res. 56:2263-2267, 1996.
    • (1996) Cancer Res , vol.56 , pp. 2263-2267
    • Trybus, T.M.1    Burgess, A.C.2    Wojno, K.J.3    Glover, T.W.4    Macoska, J.A.5
  • 62
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
    • Steck P.A., Pershouse M.A., Jasser S.A. et al: Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet. 15: 356-362, 1997.
    • (1997) Nat. Genet , vol.15 , pp. 356-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3
  • 63
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J., Yen C., Liaw D. et al: PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275:1943-1947, 1997.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 64
    • 0033579163 scopus 로고    scopus 로고
    • Mutational spectra of PTEN/MMAC1 gene: A tumor suppressor with lipid phosphatase activity
    • Ali I.U., Schriml L.M., Dean M.: Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity. J. Natl. Cancer Inst. 91:1922-1932, 1999.
    • (1999) J. Natl. Cancer Inst , vol.91 , pp. 1922-1932
    • Ali, I.U.1    Schriml, L.M.2    Dean, M.3
  • 65
    • 0034075812 scopus 로고    scopus 로고
    • 10q23.3 loss of heterozygosity is higher in lymph node-positive (pT2- 3,N+) versus lymph node-negative (pT2-3,N0) prostate cancer
    • Rubin M.A., Gerstein A., Reid K. et al: 10q23.3 loss of heterozygosity is higher in lymph node-positive (pT2- 3,N+) versus lymph node-negative (pT2-3,N0) prostate cancer. Hum. Pathol. 31:504-508, 2000.
    • (2000) Hum. Pathol , vol.31 , pp. 504-508
    • Rubin, M.A.1    Gerstein, A.2    Reid, K.3
  • 66
    • 0038642308 scopus 로고    scopus 로고
    • Prostate cancer: A dynamic illness with shifting targets
    • Shaffer D.R., Scher H.I.: Prostate cancer: a dynamic illness with shifting targets. Lancet 4:407-414, 2003.
    • (2003) Lancet , vol.4 , pp. 407-414
    • Shaffer, D.R.1    Scher, H.I.2
  • 67
    • 0032889508 scopus 로고    scopus 로고
    • Three independently deleted regions at chromosome arm 16q in human prostate cancer: Allelic loss at 16q24.1-q24.2 is associated with aggressive behaviour of the disease, recurrent growth, poor differentiation of the tumour and poor prognosis for the patient
    • Elo J.P., Harkonen P., Kyllonen A.P., Lukkarinen O., Vihko P.: Three independently deleted regions at chromosome arm 16q in human prostate cancer: allelic loss at 16q24.1-q24.2 is associated with aggressive behaviour of the disease, recurrent growth, poor differentiation of the tumour and poor prognosis for the patient. Br. J. Cancer 79:156-160, 1999.
    • (1999) Br. J. Cancer , vol.79 , pp. 156-160
    • Elo, J.P.1    Harkonen, P.2    Kyllonen, A.P.3    Lukkarinen, O.4    Vihko, P.5
  • 68
    • 0030763052 scopus 로고    scopus 로고
    • Loss of heterozygosity at 16q24.1-q24.2 is significantly associated with metastatic and aggressive behavior of prostate cancer
    • Elo J.P., Harkonen P., Kyllonen A.P. et al: Loss of heterozygosity at 16q24.1-q24.2 is significantly associated with metastatic and aggressive behavior of prostate cancer. Cancer Res. 57: 3356-3359, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3356-3359
    • Elo, J.P.1    Harkonen, P.2    Kyllonen, A.P.3
  • 69
    • 0026846630 scopus 로고
    • Loss of the 17p chromosomal region in a metastatic carcinoma of the prostate
    • Macoska J.A., Powell I.J., Sakr W., Lane M.A.: Loss of the 17p chromosomal region in a metastatic carcinoma of the prostate. J. Urol. 147:1142-1146, 1992.
    • (1992) J. Urol , vol.147 , pp. 1142-1146
    • Macoska, J.A.1    Powell, I.J.2    Sakr, W.3    Lane, M.A.4
  • 70
    • 0029873325 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosomes 10 and 17 in clinically localized prostate carcinoma
    • Ittmann M.M.: Loss of heterozygosity on chromosomes 10 and 17 in clinically localized prostate carcinoma. Prostate 28:275-281, 1996.
    • (1996) Prostate , vol.28 , pp. 275-281
    • Ittmann, M.M.1
  • 71
    • 0031029907 scopus 로고    scopus 로고
    • p53 abnormalities in primary prostate cancer: Single-strand conformation polymorphism analysis of complementary DNA in comparison with genomic DNA. The Cooperative Prostate Network
    • Gumerlock P.H., Chi S.G., Shi X.B. et al: p53 abnormalities in primary prostate cancer: single-strand conformation polymorphism analysis of complementary DNA in comparison with genomic DNA. The Cooperative Prostate Network. J. Natl. Cancer Inst. 89:66-71, 1997.
    • (1997) J. Natl. Cancer Inst , vol.89 , pp. 66-71
    • Gumerlock, P.H.1    Chi, S.G.2    Shi, X.B.3
  • 72
    • 0029783149 scopus 로고    scopus 로고
    • An uncertain role for p53 gene alterations in human prostate cancers
    • Brooks J.D., Bova G.S., Ewing C.M. et al: An uncertain role for p53 gene alterations in human prostate cancers. Cancer Res. 56: 3814-3822, 1998.
    • (1998) Cancer Res , vol.56 , pp. 3814-3822
    • Brooks, J.D.1    Bova, G.S.2    Ewing, C.M.3
  • 73
    • 0032764893 scopus 로고    scopus 로고
    • Common mutations in BRCA1 and BRCA2 do not contribute to early prostate cancer in Jewish men
    • Nastiuk K.L., Mansukhani M., Terry M.B. et al: Common mutations in BRCA1 and BRCA2 do not contribute to early prostate cancer in Jewish men. Prostate 40:172-177, 1999.
    • (1999) Prostate , vol.40 , pp. 172-177
    • Nastiuk, K.L.1    Mansukhani, M.2    Terry, M.B.3
  • 75
    • 14444267766 scopus 로고    scopus 로고
    • Identification of two distinct deleted regions on chromosome 13 in prostate cancer
    • Li C., Larsson C., Futreal A. et al. Identification of two distinct deleted regions on chromosome 13 in prostate cancer. Oncogene 16:481-487, 1998.
    • (1998) Oncogene , vol.16 , pp. 481-487
    • Li, C.1    Larsson, C.2    Futreal, A.3
  • 76
    • 0034660852 scopus 로고    scopus 로고
    • Deletion at 13q21 is associated with aggressive prostate cancers
    • Dong J.T., Chen C., Stultz B.G., Isaacs J.T., Frierson H.F.: Deletion at 13q21 is associated with aggressive prostate cancers. Cancer Res. 60:3880-3883, 2000.
    • (2000) Cancer Res , vol.60 , pp. 3880-3883
    • Dong, J.T.1    Chen, C.2    Stultz, B.G.3    Isaacs, J.T.4    Frierson, H.F.5
  • 77
    • 0030931361 scopus 로고    scopus 로고
    • Retinoblastoma protein-dependent growth signal conflict and caspase activity are required for protein kinase C-signaled apoptosis of prostate epithelial cells
    • Zhao X., Gschwend J.E., Powell C.T., Foster R.G., Day K.C., Day M.L.: Retinoblastoma protein-dependent growth signal conflict and caspase activity are required for protein kinase C-signaled apoptosis of prostate epithelial cells. J. Biol. Chem. 272:22751-22757, 1997.
    • (1997) J. Biol. Chem , vol.272 , pp. 22751-22757
    • Zhao, X.1    Gschwend, J.E.2    Powell, C.T.3    Foster, R.G.4    Day, K.C.5    Day, M.L.6
  • 78
    • 17144463251 scopus 로고    scopus 로고
    • Abnormal expression of MDM2 in prostate carcinoma
    • Leite K.R., Franco M.F., Srougi M. et al: Abnormal expression of MDM2 in prostate carcinoma. Mod. Pathol. 14:428-436, 2001.
    • (2001) Mod. Pathol , vol.14 , pp. 428-436
    • Leite, K.R.1    Franco, M.F.2    Srougi, M.3
  • 79
    • 0141482040 scopus 로고    scopus 로고
    • Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy
    • Zhang Z., Li M., Wang H., Agrawal S., Zhang R.: Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy. Proc. Natl. Acad. Sci.USA 100:11636-11641, 2003.
    • (2003) Proc. Natl. Acad. Sci.USA , vol.100 , pp. 11636-11641
    • Zhang, Z.1    Li, M.2    Wang, H.3    Agrawal, S.4    Zhang, R.5
  • 81
    • 0034001925 scopus 로고    scopus 로고
    • Fragile histidine triad gene expression in primary prostate cancer and in an in vitro model
    • Guo Z., Johansson S.L., Rhim J.S., Vishwanatha J.K.: Fragile histidine triad gene expression in primary prostate cancer and in an in vitro model. Prostate. 43:101-110, 2000.
    • (2000) Prostate , vol.43 , pp. 101-110
    • Guo, Z.1    Johansson, S.L.2    Rhim, J.S.3    Vishwanatha, J.K.4
  • 82
    • 0037443586 scopus 로고    scopus 로고
    • Down-regulation of fragile histidine triad expression in prostate carcinoma
    • Fouts R.L., Sandusky G.E., Zhang S., et al: Down-regulation of fragile histidine triad expression in prostate carcinoma. Cancer 97:1447-1452, 2003.
    • (2003) Cancer , vol.97 , pp. 1447-1452
    • Fouts, R.L.1    Sandusky, G.E.2    Zhang, S.3
  • 83
    • 0029045402 scopus 로고
    • Implication of cell kinetic changes during the progression of human prostatic cancer
    • Berges R.R., Vukanovic J., Epstein J.I. et al: Implication of cell kinetic changes during the progression of human prostatic cancer. Clin. Cancer Res. 1:473-480, 1995.
    • (1995) Clin. Cancer Res , vol.1 , pp. 473-480
    • Berges, R.R.1    Vukanovic, J.2    Epstein, J.I.3
  • 84
    • 0032980308 scopus 로고    scopus 로고
    • The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer
    • Tsihlias J., Kapusta L., Slingerland J.: The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. Annu. Rev. Med. 50:401-423, 1999.
    • (1999) Annu. Rev. Med , vol.50 , pp. 401-423
    • Tsihlias, J.1    Kapusta, L.2    Slingerland, J.3
  • 85
    • 0001746766 scopus 로고    scopus 로고
    • Role of p27 in prostate carcinogenesis
    • Macri E., Loda M.: Role of p27 in prostate carcinogenesis. Cancer Metastasis Rev. 17:337-344, 1999.
    • (1999) Cancer Metastasis Rev , vol.17 , pp. 337-344
    • Macri, E.1    Loda, M.2
  • 86
    • 0031409280 scopus 로고    scopus 로고
    • Loss of the cyclin-dependent kinase inhibitor p27(Kip1) protein in human prostate cancer correlates with tumor grade
    • Guo Y., Sklar G.N., Borkowski A., Kyprianou N.: Loss of the cyclin-dependent kinase inhibitor p27(Kip1) protein in human prostate cancer correlates with tumor grade. Clin. Cancer Res. 3:2269-2274, 1997.
    • (1997) Clin. Cancer Res , vol.3 , pp. 2269-2274
    • Guo, Y.1    Sklar, G.N.2    Borkowski, A.3    Kyprianou, N.4
  • 87
    • 0032540544 scopus 로고    scopus 로고
    • Association of p27Kip1 levels with recurrence and survival in patients with stage C prostate carcinoma
    • Cote R.J., Shi Y., Groshen S., et al: Association of p27Kip1 levels with recurrence and survival in patients with stage C prostate carcinoma. J. Natl. Cancer Inst. 90: 916-920, 1998.
    • (1998) J. Natl. Cancer Inst , vol.90 , pp. 916-920
    • Cote, R.J.1    Shi, Y.2    Groshen, S.3
  • 88
    • 0031683673 scopus 로고    scopus 로고
    • Prostate stem cell compartments: Expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells
    • De Marzo A.M., Meeker A.K., Epstein J.I., Coffey D.S.: Prostate stem cell compartments: Expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells. Am. J. Pathol. 153:911-919, 1998a.
    • (1998) Am. J. Pathol , vol.153 , pp. 911-919
    • De Marzo, A.M.1    Meeker, A.K.2    Epstein, J.I.3    Coffey, D.S.4
  • 89
    • 0031930822 scopus 로고    scopus 로고
    • Low p27 expression predicts poor disease-free survival in patients with prostate cancer
    • Yang R.M., Naitoh J., Murphy M. et al: Low p27 expression predicts poor disease-free survival in patients with prostate cancer. J. Urol. 159:941-945, 1998.
    • (1998) J. Urol , vol.159 , pp. 941-945
    • Yang, R.M.1    Naitoh, J.2    Murphy, M.3
  • 90
    • 0032475438 scopus 로고    scopus 로고
    • Distinct altered patterns of p27KIP1 gene expression in benign prostatic hyperplasia and prostatic carcinoma
    • Cordon-Cardo C., Koff A., Drobnjak et al: Distinct altered patterns of p27KIP1 gene expression in benign prostatic hyperplasia and prostatic carcinoma. J. Natl. Cancer Inst. 90:1284-1291, 1998.
    • (1998) J. Natl. Cancer Inst , vol.90 , pp. 1284-1291
    • Cordon-Cardo, C.1    Koff, A.2    Drobnjak3
  • 91
    • 0030792699 scopus 로고    scopus 로고
    • Frequent alteration of CDKN2 (p16(INK4A)/MTS1) expression in human primary prostate carcinomas
    • Chi S.G., deVere White R.W., Muenzer J.T., Gumerlock P.H.: Frequent alteration of CDKN2 (p16(INK4A)/MTS1) expression in human primary prostate carcinomas. Clin. Cancer Res. 3:1889-1897, 1997.
    • (1997) Clin. Cancer Res , vol.3 , pp. 1889-1897
    • Chi, S.G.1    deVere White, R.W.2    Muenzer, J.T.3    Gumerlock, P.H.4
  • 92
    • 0030464202 scopus 로고    scopus 로고
    • Absence of p16/MTS1 gene mutations in human prostate cancer
    • Chen W., Weghorst C.M., Sabourin C.L. et al: Absence of p16/MTS1 gene mutations in human prostate cancer. Carcinogenesis 17:2603-2607, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 2603-2607
    • Chen, W.1    Weghorst, C.M.2    Sabourin, C.L.3
  • 93
    • 0030015955 scopus 로고    scopus 로고
    • Tamimi Y., Bringuier P.P., Smit F., van Bokhoven A., Debruyne F.M., Schalken J.A.: p 16 mutations/deletions are not frequent events in prostate cancer. Brit. J. Cancer 74: 120-122, 1996.
    • Tamimi Y., Bringuier P.P., Smit F., van Bokhoven A., Debruyne F.M., Schalken J.A.: p 16 mutations/deletions are not frequent events in prostate cancer. Brit. J. Cancer 74: 120-122, 1996.
  • 94
    • 0030892851 scopus 로고    scopus 로고
    • Mutations of the p16 gene product are rare in prostate cancer
    • Gaddipati J.P., McLeod D.G., Sesterhenn I.A. et al: Mutations of the p16 gene product are rare in prostate cancer. Prostate 30:188-194, 1997.
    • (1997) Prostate , vol.30 , pp. 188-194
    • Gaddipati, J.P.1    McLeod, D.G.2    Sesterhenn, I.A.3
  • 95
    • 0031031325 scopus 로고    scopus 로고
    • p16 (CD-KN2/MTS1) gene deletions are rare in prostatic carcinomas in the United States and Japan
    • Mangold K.A., Takahashi H., Brandigi C. et al: p16 (CD-KN2/MTS1) gene deletions are rare in prostatic carcinomas in the United States and Japan. J. Urol. 157:1117-1120, 1997.
    • (1997) J. Urol , vol.157 , pp. 1117-1120
    • Mangold, K.A.1    Takahashi, H.2    Brandigi, C.3
  • 96
    • 0034650587 scopus 로고    scopus 로고
    • Prognostic significance of p16 and CDK4 proteins in localized prostate carcinoma
    • Halvorsen O.J., Hostmark J., Haukaas S., Hoisaeter P.A., Akslen L.A.: Prognostic significance of p16 and CDK4 proteins in localized prostate carcinoma. Cancer 88:416-424, 2000.
    • (2000) Cancer , vol.88 , pp. 416-424
    • Halvorsen, O.J.1    Hostmark, J.2    Haukaas, S.3    Hoisaeter, P.A.4    Akslen, L.A.5
  • 97
    • 0032948380 scopus 로고    scopus 로고
    • Overexpression of the cyclin-dependent kinase inhibitor p16 is associated with tumor recurrence in human prostate cancer
    • Lee C.T., Capodieci P., Osman I. et al: Overexpression of the cyclin-dependent kinase inhibitor p16 is associated with tumor recurrence in human prostate cancer. Clin. Cancer Res. 5: 977-983, 1999.
    • (1999) Clin. Cancer Res , vol.5 , pp. 977-983
    • Lee, C.T.1    Capodieci, P.2    Osman, I.3
  • 98
    • 1842626080 scopus 로고    scopus 로고
    • Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer
    • Olapade-Olaopa E.O., Moscatello D.K., MacKay E.H. et al: Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer. Br. J. Cancer 82:186-194, 2000.
    • (2000) Br. J. Cancer , vol.82 , pp. 186-194
    • Olapade-Olaopa, E.O.1    Moscatello, D.K.2    MacKay, E.H.3
  • 99
    • 0030877481 scopus 로고    scopus 로고
    • HER-2/neu gene amplification status in prostate cancer by fluorescence in situ hybridization
    • Ross J.S., Sheehan C., Hayner-Buchan A.M. et al: HER-2/neu gene amplification status in prostate cancer by fluorescence in situ hybridization. Hum. Pathol. 28:827-833, 1997.
    • (1997) Hum. Pathol , vol.28 , pp. 827-833
    • Ross, J.S.1    Sheehan, C.2    Hayner-Buchan, A.M.3
  • 100
    • 0030978334 scopus 로고    scopus 로고
    • Prognostic significance of HER-2/neu gene amplification status by fluorescence in situ hybridization of prostate carcinoma
    • Ross J.S., Sheehan C.E., Hayner-Buchan A.M. et al: Prognostic significance of HER-2/neu gene amplification status by fluorescence in situ hybridization of prostate carcinoma. Cancer 79:2162-2170, 1997.
    • (1997) Cancer , vol.79 , pp. 2162-2170
    • Ross, J.S.1    Sheehan, C.E.2    Hayner-Buchan, A.M.3
  • 102
    • 0032519561 scopus 로고    scopus 로고
    • Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium
    • Zhang W., Kapusta L.R., Slingerland J.M., Klotz L.H.: Telomerase activity in prostate cancer, prostatic intraepithelial neoplasia, and benign prostatic epithelium. Cancer Res. 58:619-621, 1998.
    • (1998) Cancer Res , vol.58 , pp. 619-621
    • Zhang, W.1    Kapusta, L.R.2    Slingerland, J.M.3    Klotz, L.H.4
  • 103
    • 0032840643 scopus 로고    scopus 로고
    • Immunohistochemical comparative analysis of transforming growth factor alpha, epidermal growth factor, and epidermal growth factor receptor in normal, hyperplastic and neoplastic human prostates
    • De Miguel P., Royuela M., Bethencourt R., Ruiz A., Fraile B., Paniagua R.: Immunohistochemical comparative analysis of transforming growth factor alpha, epidermal growth factor, and epidermal growth factor receptor in normal, hyperplastic and neoplastic human prostates. Cytokine 11:722-727, 1999.
    • (1999) Cytokine , vol.11 , pp. 722-727
    • De Miguel, P.1    Royuela, M.2    Bethencourt, R.3    Ruiz, A.4    Fraile, B.5    Paniagua, R.6
  • 104
    • 0036985311 scopus 로고    scopus 로고
    • Backbone modification alters the efficacy of antisense oligonucleotides directed against mRNA encoding either TGF-alpha or EGFR in the treatment of prostate cancer cell lines
    • Rubenstein M., Slobodskoy L., Mirochnik Y., Guinan P.: Backbone modification alters the efficacy of antisense oligonucleotides directed against mRNA encoding either TGF-alpha or EGFR in the treatment of prostate cancer cell lines. Methods Find. Exp. Clin. Pharmacol. 24:649-652, 2002.
    • (2002) Methods Find. Exp. Clin. Pharmacol , vol.24 , pp. 649-652
    • Rubenstein, M.1    Slobodskoy, L.2    Mirochnik, Y.3    Guinan, P.4
  • 106
    • 9544242713 scopus 로고    scopus 로고
    • Loss of expression of transforming growth factor beta type I and type II receptors correlates with tumor grade in human prostate cancer tissues
    • Kim I.Y., Ahn H.J., Zelner D.J., et al: Loss of expression of transforming growth factor beta type I and type II receptors correlates with tumor grade in human prostate cancer tissues. Clin. Cancer Res. 2:1255-1261, 1996.
    • (1996) Clin. Cancer Res , vol.2 , pp. 1255-1261
    • Kim, I.Y.1    Ahn, H.J.2    Zelner, D.J.3
  • 107
    • 0029439502 scopus 로고
    • The insulin-like growth factor system in the prostate
    • Peehl D.M., Cohen P., Rosenfeld R.G.: The insulin-like growth factor system in the prostate. World J. Urol. 13:306-311, 1995.
    • (1995) World J. Urol , vol.13 , pp. 306-311
    • Peehl, D.M.1    Cohen, P.2    Rosenfeld, R.G.3
  • 108
    • 0010509214 scopus 로고    scopus 로고
    • Insulin-like growth factors and prostate cancer
    • Pollak M., Beamer W., Zhang J.C.: Insulin-like growth factors and prostate cancer, Cancer Metastasis Rev. 17:383-390, 1998.
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 383-390
    • Pollak, M.1    Beamer, W.2    Zhang, J.C.3
  • 109
    • 0031897867 scopus 로고    scopus 로고
    • Differential expression of insulin-like growth factor binding proteins in high versus low Gleason score prostate cancer
    • Figueroa J.A., De Raad S., Tadlock L., Speights V.O., Rinehart J.J.: Differential expression of insulin-like growth factor binding proteins in high versus low Gleason score prostate cancer. J. Urol. 159:1379-1383, 1998.
    • (1998) J. Urol , vol.159 , pp. 1379-1383
    • Figueroa, J.A.1    De Raad, S.2    Tadlock, L.3    Speights, V.O.4    Rinehart, J.J.5
  • 110
    • 0032559272 scopus 로고    scopus 로고
    • Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study
    • Chan J.M., Stampfer M.J., Giovannucci E. et al: Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 279:563-566, 1998.
    • (1998) Science , vol.279 , pp. 563-566
    • Chan, J.M.1    Stampfer, M.J.2    Giovannucci, E.3
  • 111
    • 0027407639 scopus 로고
    • Inhibition of growth of prostatic cancer cell lines by peptide analogues of insulin-like growth factor 1
    • Pietrzkowski Z., Mulholland G., Gomella L., Jameson B.A., Wernicke D., Baserga R.: Inhibition of growth of prostatic cancer cell lines by peptide analogues of insulin-like growth factor 1. Cancer Res. 53:1102-1106, 1993.
    • (1993) Cancer Res , vol.53 , pp. 1102-1106
    • Pietrzkowski, Z.1    Mulholland, G.2    Gomella, L.3    Jameson, B.A.4    Wernicke, D.5    Baserga, R.6
  • 112
    • 0029885705 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) system components in human prostatic cancer cell-lines: LNCaP, DU145, and PC-3 cells
    • Kimura G., Kasuya J., Giannini S. et al: Insulin-like growth factor (IGF) system components in human prostatic cancer cell-lines: LNCaP, DU145, and PC-3 cells. Int. J. Urol. 3:39-46, 1996.
    • (1996) Int. J. Urol , vol.3 , pp. 39-46
    • Kimura, G.1    Kasuya, J.2    Giannini, S.3
  • 113
    • 0032880248 scopus 로고    scopus 로고
    • Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer
    • Drachenberg D.E., Elgamal A.A., Rowbotham R., Peterson M., Murphy G.P.: Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer. Prostate 41:127-133, 1999.
    • (1999) Prostate , vol.41 , pp. 127-133
    • Drachenberg, D.E.1    Elgamal, A.A.2    Rowbotham, R.3    Peterson, M.4    Murphy, G.P.5
  • 114
    • 0033911711 scopus 로고    scopus 로고
    • Serum interleukin 6 as a prognostic factor in patients with prostate cancer
    • Nakashima J., Tachibana M., Horiguchi Y. et al: Serum interleukin 6 as a prognostic factor in patients with prostate cancer. Clin. Cancer Res. 6:2702-2706, 2000.
    • (2000) Clin. Cancer Res , vol.6 , pp. 2702-2706
    • Nakashima, J.1    Tachibana, M.2    Horiguchi, Y.3
  • 115
    • 0036183346 scopus 로고    scopus 로고
    • A population-based study of daily non steroidal anti inflammatory drug use and prostate cancer
    • Roberts R.O., Jacobson D.J., Girman C.J. et al: A population-based study of daily non steroidal anti inflammatory drug use and prostate cancer. Mayo Clin. Proc. 77:219-225, 2002.
    • (2002) Mayo Clin. Proc , vol.77 , pp. 219-225
    • Roberts, R.O.1    Jacobson, D.J.2    Girman, C.J.3
  • 116
    • 0035893745 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma
    • Zha S., Gage W.R., Sauvageot J. et al: Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma. Cancer Res. 61:8617-8623, 2001.
    • (2001) Cancer Res , vol.61 , pp. 8617-8623
    • Zha, S.1    Gage, W.R.2    Sauvageot, J.3
  • 117
    • 0032188853 scopus 로고    scopus 로고
    • NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells
    • Liu X.H., Yao S., Kirschenbaum A., Levine A.C.: NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells. Cancer Res. 58:4245-4249, 1998.
    • (1998) Cancer Res , vol.58 , pp. 4245-4249
    • Liu, X.H.1    Yao, S.2    Kirschenbaum, A.3    Levine, A.C.4
  • 118
    • 0034254972 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in prostate carcinoma
    • Yoshimura R., Sano H., Masuda C. et al: Expression of cyclooxygenase-2 in prostate carcinoma. Cancer 89:589-596, 2000.
    • (2000) Cancer , vol.89 , pp. 589-596
    • Yoshimura, R.1    Sano, H.2    Masuda, C.3
  • 119
    • 0033781990 scopus 로고    scopus 로고
    • Cytoplasmic induction and over-expression of cyclooxygenase-2 in human prostate cancer: Implications for prevention and treatment
    • Madaan S., Abel P.D., Chaudhary K.S., Hewitt R., Stott M.A., Stamp G.W., Lalani E.N.: Cytoplasmic induction and over-expression of cyclooxygenase-2 in human prostate cancer: implications for prevention and treatment. BJU Int. 86:736-741, 2000.
    • (2000) BJU Int , vol.86 , pp. 736-741
    • Madaan, S.1    Abel, P.D.2    Chaudhary, K.S.3    Hewitt, R.4    Stott, M.A.5    Stamp, G.W.6    Lalani, E.N.7
  • 120
    • 0035011423 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in prostate adenocarcinoma and benign prostatic hyperplasia
    • Lee L.M., Pan C.C., Cheng C.J., Chi C.W., Liu T.Y.: Expression of cyclooxygenase-2 in prostate adenocarcinoma and benign prostatic hyperplasia. Anticancer Res. 21:1291-1294, 2001.
    • (2001) Anticancer Res , vol.21 , pp. 1291-1294
    • Lee, L.M.1    Pan, C.C.2    Cheng, C.J.3    Chi, C.W.4    Liu, T.Y.5
  • 121
    • 0038625360 scopus 로고    scopus 로고
    • Cyclooxygenase-2 as a potential target in the prevention and treatment of genitourinary tumors: A review
    • Pruthi R.S., Derksen E., Gaston K.: Cyclooxygenase-2 as a potential target in the prevention and treatment of genitourinary tumors: a review. J. Urol. 169:2352-2359, 2003.
    • (2003) J. Urol , vol.169 , pp. 2352-2359
    • Pruthi, R.S.1    Derksen, E.2    Gaston, K.3
  • 122
    • 0035104125 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase-2 and nitric oxide synthase-2 in human prostate cancer
    • Uotila P., Valve E., Martikainen P., Nevalainen M., Nurmi M., and Harkonen P.: Increased expression of cyclooxygenase-2 and nitric oxide synthase-2 in human prostate cancer. Urol. Res. 29:23-28, 2001.
    • (2001) Urol. Res , vol.29 , pp. 23-28
    • Uotila, P.1    Valve, E.2    Martikainen, P.3    Nevalainen, M.4    Nurmi, M.5    Harkonen, P.6
  • 123
    • 0035569290 scopus 로고    scopus 로고
    • Induction of apoptosis by cyclooxygenase-2 inhibitors in prostate cancer cell lines
    • Kamijo T., Sato T., Nagatomi Y., Kitamura T.: Induction of apoptosis by cyclooxygenase-2 inhibitors in prostate cancer cell lines. Int. J. Urol. 8:S35-39, 2001.
    • (2001) Int. J. Urol , vol.8
    • Kamijo, T.1    Sato, T.2    Nagatomi, Y.3    Kitamura, T.4
  • 124
    • 0034671358 scopus 로고    scopus 로고
    • Heat shock protein expression independently predicts clinical outcome in prostate cancer
    • Cornford P.A., Dodson A.R., Parsons K.F., et al: Heat shock protein expression independently predicts clinical outcome in prostate cancer. Cancer Res. 60:7099-7105, 2000.
    • (2000) Cancer Res , vol.60 , pp. 7099-7105
    • Cornford, P.A.1    Dodson, A.R.2    Parsons, K.F.3
  • 126
    • 0037213193 scopus 로고    scopus 로고
    • Heat shock proteins: Their role in urological tumors
    • Lebret T., Watson R.W., Fitzpatrick J.M.: Heat shock proteins: their role in urological tumors. J. Urol. 169:338-346, 2003.
    • (2003) J. Urol , vol.169 , pp. 338-346
    • Lebret, T.1    Watson, R.W.2    Fitzpatrick, J.M.3
  • 127
    • 0036786205 scopus 로고    scopus 로고
    • Mechanism of antiandrogen action: Key role of hsp90 in conformational change and transcriptional activity of the androgen receptor
    • Georget V., Terouanne B., Nicolas J.C., Sultan C.: Mechanism of antiandrogen action: key role of hsp90 in conformational change and transcriptional activity of the androgen receptor. Biochemistry 41:11824-11831, 2002.
    • (2002) Biochemistry , vol.41 , pp. 11824-11831
    • Georget, V.1    Terouanne, B.2    Nicolas, J.C.3    Sultan, C.4
  • 128
    • 0035341888 scopus 로고    scopus 로고
    • Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression
    • Pizer E.S., Pflug B.R., Bova G.S., Han W.F., Udan M.S., Nelson J.B.: Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression. Prostate 47:102-110, 2001.
    • (2001) Prostate , vol.47 , pp. 102-110
    • Pizer, E.S.1    Pflug, B.R.2    Bova, G.S.3    Han, W.F.4    Udan, M.S.5    Nelson, J.B.6
  • 129
    • 0036497907 scopus 로고    scopus 로고
    • Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer
    • Swinnen J.V., Roskams T., Joniau S., et al: Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer. Int. J. Cancer 98:19-22, 2002.
    • (2002) Int. J. Cancer , vol.98 , pp. 19-22
    • Swinnen, J.V.1    Roskams, T.2    Joniau, S.3
  • 130
    • 0037012476 scopus 로고    scopus 로고
    • alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer
    • Rubin M.A., Zhou M., Dhanasekaran S.M., et al: alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer. JAMA 287:1662-1670, 2002.
    • (2002) JAMA , vol.287 , pp. 1662-1670
    • Rubin, M.A.1    Zhou, M.2    Dhanasekaran, S.M.3
  • 131
    • 17344393447 scopus 로고    scopus 로고
    • Alpha-methylacyl-CoA racemase: A new molecular marker for prostate cancer
    • Luo J., Zha S., Gage W.R., et al: Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer. Cancer Res. 62:2220-2226, 2002.
    • (2002) Cancer Res , vol.62 , pp. 2220-2226
    • Luo, J.1    Zha, S.2    Gage, W.R.3
  • 132
    • 0030954428 scopus 로고    scopus 로고
    • CG island methylation changes near the GSTP1 gene in prostatic carcinoma cells detected using the polymerase chain reaction: A new prostate cancer biomarker
    • Lee W.H., Isaacs W.B., Bova G.S., Nelson W.G.: CG island methylation changes near the GSTP1 gene in prostatic carcinoma cells detected using the polymerase chain reaction: a new prostate cancer biomarker. Cancer Epidemiol. Biomarkers Prev. 6:443-450, 1997.
    • (1997) Cancer Epidemiol. Biomarkers Prev , vol.6 , pp. 443-450
    • Lee, W.H.1    Isaacs, W.B.2    Bova, G.S.3    Nelson, W.G.4
  • 133
    • 0029802619 scopus 로고    scopus 로고
    • Androgen receptors in prostate cancer
    • Bentel J.M., Tilley W.D.: Androgen receptors in prostate cancer. J. Endocrinol. 151:1-11, 1996.
    • (1996) J. Endocrinol , vol.151 , pp. 1-11
    • Bentel, J.M.1    Tilley, W.D.2
  • 134
    • 0031946389 scopus 로고    scopus 로고
    • Expression, structure, and function of androgen receptor in advanced prostatic carcinoma
    • Culig Z., Hobisch A., Hittmair A., et al: Expression, structure, and function of androgen receptor in advanced prostatic carcinoma. Prostate 35: 63-70, 1998.
    • (1998) Prostate , vol.35 , pp. 63-70
    • Culig, Z.1    Hobisch, A.2    Hittmair, A.3
  • 135
    • 0031975628 scopus 로고    scopus 로고
    • Androgen receptor gene and hormonal therapy failure of prostate cancer
    • Koivisto P., Kolmer M., Visakorpi T., Kallioniemi O.P.: Androgen receptor gene and hormonal therapy failure of prostate cancer. Am. J. Pathol. 152: 1-9, 1998.
    • (1998) Am. J. Pathol , vol.152 , pp. 1-9
    • Koivisto, P.1    Kolmer, M.2    Visakorpi, T.3    Kallioniemi, O.P.4
  • 136
    • 0025045495 scopus 로고
    • Androgen receptor gene expression in human prostate carcinoma cell lines
    • Tilley W.D., Wilson C.M., Marcelli M., McPhaul M.J.: Androgen receptor gene expression in human prostate carcinoma cell lines. Cancer Res. 50: 5382-5386, 1990.
    • (1990) Cancer Res , vol.50 , pp. 5382-5386
    • Tilley, W.D.1    Wilson, C.M.2    Marcelli, M.3    McPhaul, M.J.4
  • 137
    • 0029011116 scopus 로고
    • Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
    • Taplin M.E., Bubley G.J., Shuster T.D., et al: Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. N. Engl. J. Med. 332:1393-1398, 1995.
    • (1995) N. Engl. J. Med , vol.332 , pp. 1393-1398
    • Taplin, M.E.1    Bubley, G.J.2    Shuster, T.D.3
  • 138
    • 0034652723 scopus 로고    scopus 로고
    • Androgen receptor mutations in prostate cancer
    • Marcelli M., Ittmann M., Mariani S. et al: Androgen receptor mutations in prostate cancer. Cancer Res. 60:944-949, 2000.
    • (2000) Cancer Res , vol.60 , pp. 944-949
    • Marcelli, M.1    Ittmann, M.2    Mariani, S.3
  • 139
    • 0025806437 scopus 로고
    • Androgen receptors in endocrine-therapy-resistant human prostate cancer
    • van der Kwast T.H., Schalken J., Ruizeveld de Winter J.A. et al: Androgen receptors in endocrine-therapy-resistant human prostate cancer. Intl. J. Cancer 48: 189-193, 1991.
    • (1991) Intl. J. Cancer , vol.48 , pp. 189-193
    • van der Kwast, T.H.1    Schalken, J.2    Ruizeveld de Winter, J.A.3
  • 140
    • 0343698426 scopus 로고
    • Androgen receptor status in localized and locally progressive hormone refractory human prostate cancer
    • Ruizeveld de Winter J.A., Janssen P.J., Sleddens H.M. et al: Androgen receptor status in localized and locally progressive hormone refractory human prostate cancer. Am. J. Pathol. 144:735-746, 1994.
    • (1994) Am. J. Pathol , vol.144 , pp. 735-746
    • Ruizeveld de Winter, J.A.1    Janssen, P.J.2    Sleddens, H.M.3
  • 141
    • 0029072101 scopus 로고
    • Distant metastases from prostatic carcinoma express androgen receptor protein
    • Hobisch A., Culig Z., Radmayr C., Bartsch G., Klocker H., Hittmair A.: Distant metastases from prostatic carcinoma express androgen receptor protein. Cancer Res. 55: 3068-3072, 1995.
    • (1995) Cancer Res , vol.55 , pp. 3068-3072
    • Hobisch, A.1    Culig, Z.2    Radmayr, C.3    Bartsch, G.4    Klocker, H.5    Hittmair, A.6
  • 142
    • 0032835660 scopus 로고    scopus 로고
    • Androgen receptor expression in prostatic intraepithelial neoplasia and cancer
    • Sweat S.D., Pacelli A., Bergstralh E.J., Slezak J.M., Bostwick D.G.: Androgen receptor expression in prostatic intraepithelial neoplasia and cancer. J. Urol. 161:1229- 1232, 1999.
    • (1999) J. Urol , vol.161 , pp. 1229-1232
    • Sweat, S.D.1    Pacelli, A.2    Bergstralh, E.J.3    Slezak, J.M.4    Bostwick, D.G.5
  • 143
    • 22044447801 scopus 로고    scopus 로고
    • Differently regulated androgen receptor transcriptional complex in prostate cancer compared with normal prostate
    • Kinoshita M., Nakagawa T., Shimizu A., Katsuoka Y.: Differently regulated androgen receptor transcriptional complex in prostate cancer compared with normal prostate. Int. J. Urol. 12:390-397, 2005.
    • (2005) Int. J. Urol , vol.12 , pp. 390-397
    • Kinoshita, M.1    Nakagawa, T.2    Shimizu, A.3    Katsuoka, Y.4
  • 144
    • 0242525635 scopus 로고    scopus 로고
    • Gene amplifications associated with the development of hormone resistant prostate cancer
    • Edwards J., Krishna N.S., Witton C.J., Bartlett J.M.S.: Gene amplifications associated with the development of hormone resistant prostate cancer. Clin. Cancer Res. 9:2571-2581, 2003.
    • (2003) Clin. Cancer Res , vol.9 , pp. 2571-2581
    • Edwards, J.1    Krishna, N.S.2    Witton, C.J.3    Bartlett, J.M.S.4
  • 145
  • 146
    • 0037093826 scopus 로고    scopus 로고
    • Her-2/neu is overex-pressed infrequently in patients with prostate carcinoma
    • Lara P.N., Meyers F.J., Gray C.R. et al: Her-2/neu is overex-pressed infrequently in patients with prostate carcinoma. Cancer 94:2584-2589, 2002.
    • (2002) Cancer , vol.94 , pp. 2584-2589
    • Lara, P.N.1    Meyers, F.J.2    Gray, C.R.3
  • 147
    • 0042477896 scopus 로고    scopus 로고
    • Involvement of growth factor receptors of the epidermal growth factor receptor family in prostate cancer development and progression to androgen independence
    • Lorenzo G.D., Bianco R., Torora G., Ciardillo F.: Involvement of growth factor receptors of the epidermal growth factor receptor family in prostate cancer development and progression to androgen independence. Clin. Prostate Cancer 2:50-57, 2003.
    • (2003) Clin. Prostate Cancer , vol.2 , pp. 50-57
    • Lorenzo, G.D.1    Bianco, R.2    Torora, G.3    Ciardillo, F.4
  • 148
    • 0029851180 scopus 로고    scopus 로고
    • bcl-2 overexpression combined with p53 protein accumulation correlates with hormone-refractory prostate cancer
    • Apakama I., Robinson M.C., Walter N.M. et al: bcl-2 overexpression combined with p53 protein accumulation correlates with hormone-refractory prostate cancer. Brit. J. Cancer 74:1258-1262, 1996.
    • (1996) Brit. J. Cancer , vol.74 , pp. 1258-1262
    • Apakama, I.1    Robinson, M.C.2    Walter, N.M.3
  • 149
    • 1342325380 scopus 로고    scopus 로고
    • Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer
    • Gregory C.W., Fei X., Ponguta L., et al: Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer. J. Biol. Chem. 179:7119-7130, 2004
    • (2004) J. Biol. Chem , vol.179 , pp. 7119-7130
    • Gregory, C.W.1    Fei, X.2    Ponguta, L.3
  • 150
    • 0028215671 scopus 로고
    • Frequency and characterization of p53 mutations in primary and metastatic human prostate cancer
    • Dinjens W.N., van der Weiden M.M., Schroeder F.H., Bosman F.T., Trapman J.: Frequency and characterization of p53 mutations in primary and metastatic human prostate cancer. Int. J. Cancer 56:630-3, 1994.
    • (1994) Int. J. Cancer , vol.56 , pp. 630-633
    • Dinjens, W.N.1    van der Weiden, M.M.2    Schroeder, F.H.3    Bosman, F.T.4    Trapman, J.5
  • 151
    • 0027773015 scopus 로고
    • Detection of the apoptosis-suppressing oncoprotein bcl-2 in hormone-refractory human prostate cancers
    • Colombel M., Symmans E, Gil S., et al: Detection of the apoptosis-suppressing oncoprotein bcl-2 in hormone-refractory human prostate cancers. Am. J. Pathol. 143: 390-400, 1993.
    • (1993) Am. J. Pathol , vol.143 , pp. 390-400
    • Colombel, M.1    Symmans, E.2    Gil, S.3
  • 152
    • 0029983253 scopus 로고    scopus 로고
    • Expression of bcl-2 and the progression of human and rodent prostatic cancers
    • Furuya Y., Krajewski S., Epstein J.I., Reed J.C., Isaacs J.T.: Expression of bcl-2 and the progression of human and rodent prostatic cancers. Clin. Cancer Res. 2: 389-398, 1996.
    • (1996) Clin. Cancer Res , vol.2 , pp. 389-398
    • Furuya, Y.1    Krajewski, S.2    Epstein, J.I.3    Reed, J.C.4    Isaacs, J.T.5
  • 153
    • 0029919668 scopus 로고    scopus 로고
    • Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers
    • Krajewska M., Krajewski S., Epstein J.I., et al: Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am. J. Pathol. 148:1567-1576, 1996.
    • (1996) Am. J. Pathol , vol.148 , pp. 1567-1576
    • Krajewska, M.1    Krajewski, S.2    Epstein, J.I.3
  • 154
    • 0031012825 scopus 로고    scopus 로고
    • Expression of bcl-2 oncoprotein and p53 protein accumulation in bone marrow metastases of androgen independent prostate cancer
    • McDonnell T.J., Navone N.M., Troncoso P. et al: Expression of bcl-2 oncoprotein and p53 protein accumulation in bone marrow metastases of androgen independent prostate cancer. J. Urol. 157:569-574, 1997.
    • (1997) J. Urol , vol.157 , pp. 569-574
    • McDonnell, T.J.1    Navone, N.M.2    Troncoso, P.3
  • 155
    • 0033821939 scopus 로고    scopus 로고
    • Prostate tumours from an Asian population: Examination of bax, bcl-2, p53 and ras and identification of bax as a prognostic marker
    • Chia S. J., Tang W. Y., Elnatan J., Yap W. M., Goh H. S., Smith, D. R.: Prostate tumours from an Asian population: examination of bax, bcl-2, p53 and ras and identification of bax as a prognostic marker. Br. J. Cancer. 83:761-768, 2000.
    • (2000) Br. J. Cancer , vol.83 , pp. 761-768
    • Chia, S.J.1    Tang, W.Y.2    Elnatan, J.3    Yap, W.M.4    Goh, H.S.5    Smith, D.R.6
  • 156
    • 0029048985 scopus 로고
    • KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2
    • Dong J.T., Lamb P.W., Rinker-Schaeffer C. W., et al: KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science 268:884-886, 1995.
    • (1995) Science , vol.268 , pp. 884-886
    • Dong, J.T.1    Lamb, P.W.2    Rinker-Schaeffer, C.W.3
  • 157
    • 0034285094 scopus 로고    scopus 로고
    • Methylation of a CpG island within the promoter region of the KAI1 metastasis suppressor gene is not responsible for down-regulation of KAI1 expression in invasive cancers or cancer cell lines
    • Jackson P., Millar D., Kingsley E. et al: Methylation of a CpG island within the promoter region of the KAI1 metastasis suppressor gene is not responsible for down-regulation of KAI1 expression in invasive cancers or cancer cell lines Cancer Lett. 157: 169-176, 2000.
    • (2000) Cancer Lett , vol.157 , pp. 169-176
    • Jackson, P.1    Millar, D.2    Kingsley, E.3
  • 158
    • 0031397808 scopus 로고    scopus 로고
    • The cadherin cell-cell adhesion pathway in prostate cancer progression
    • Paul R., Ewing C.M., Jarrard D.F., Isaacs W.B. The cadherin cell-cell adhesion pathway in prostate cancer progression. Br. J. Urol. 79:37-43, 1997.
    • (1997) Br. J. Urol , vol.79 , pp. 37-43
    • Paul, R.1    Ewing, C.M.2    Jarrard, D.F.3    Isaacs, W.B.4
  • 159
    • 0034235575 scopus 로고    scopus 로고
    • Cadherin switching in human prostate cancer progression
    • Tomita K., van Bokhoven A., van Leenders G.J. et al: Cadherin switching in human prostate cancer progression. Cancer Res. 60:3650-3654, 2000.
    • (2000) Cancer Res , vol.60 , pp. 3650-3654
    • Tomita, K.1    van Bokhoven, A.2    van Leenders, G.J.3
  • 160
    • 34247501208 scopus 로고    scopus 로고
    • Comprehensive genetic evaluation of common E-cadherin sequence variants and prostate cancer risk: Strong confirmation of functional promoter SNP
    • Lindstrom S., Wiklund F., Jonsson B.A. et al: Comprehensive genetic evaluation of common E-cadherin sequence variants and prostate cancer risk: strong confirmation of functional promoter SNP. Hum. Genet. 28:1-9, 2005.
    • (2005) Hum. Genet , vol.28 , pp. 1-9
    • Lindstrom, S.1    Wiklund, F.2    Jonsson, B.A.3
  • 161
    • 7744230268 scopus 로고    scopus 로고
    • Methylation of multiple genes in prostate cancer and the relationship with clinicopathological features of disease
    • Singal R., Ferdinand L., Reis I.M., Schlesselman J.J.: Methylation of multiple genes in prostate cancer and the relationship with clinicopathological features of disease. Oncol. Rep. 12:631-637, 2004.
    • (2004) Oncol. Rep , vol.12 , pp. 631-637
    • Singal, R.1    Ferdinand, L.2    Reis, I.M.3    Schlesselman, J.J.4
  • 164
    • 0031981414 scopus 로고    scopus 로고
    • CD44 and CD44v6 downregulation in clinical prostatic carcinoma: Relation to Gleason grade and cytoarchitecture
    • De Marzo A.M., Bradshaw C., Sauvageot J., Epstein J.I., Miller G.J.: CD44 and CD44v6 downregulation in clinical prostatic carcinoma: relation to Gleason grade and cytoarchitecture. Prostate 34:162-168, 1998.
    • (1998) Prostate , vol.34 , pp. 162-168
    • De Marzo, A.M.1    Bradshaw, C.2    Sauvageot, J.3    Epstein, J.I.4    Miller, G.J.5
  • 165
    • 0031596534 scopus 로고    scopus 로고
    • Correlation of p34cdc2 cyclin-dependent kinase overexpression, CD44s downregulation, and HER-2/neu oncogene amplification with recurrence in prostatic adenocarcinomas
    • Kallakury B.V., Sheehan C.E., Ambros R.A. et al: Correlation of p34cdc2 cyclin-dependent kinase overexpression, CD44s downregulation, and HER-2/neu oncogene amplification with recurrence in prostatic adenocarcinomas. J. Clin. Oncol. 16:1302-1309, 1998.
    • (1998) J. Clin. Oncol , vol.16 , pp. 1302-1309
    • Kallakury, B.V.1    Sheehan, C.E.2    Ambros, R.A.3
  • 166
    • 0032479556 scopus 로고    scopus 로고
    • Relationship between CD44 expression and differentiation of human prostate adenocarcinomas
    • Takahashi S., Kimoto N., Orita S., Cui L., Sakakibara M., Shirai T.: Relationship between CD44 expression and differentiation of human prostate adenocarcinomas. Cancer Lett. 129:97-102, 1998.
    • (1998) Cancer Lett , vol.129 , pp. 97-102
    • Takahashi, S.1    Kimoto, N.2    Orita, S.3    Cui, L.4    Sakakibara, M.5    Shirai, T.6
  • 167
    • 0032774407 scopus 로고    scopus 로고
    • Metastasis-related genes in prostate cancer: The role of caveolin-1
    • Thompson T.C.: Metastasis-related genes in prostate cancer: the role of caveolin-1. Cancer Metastasis Rev. 17:439-442, 1998.
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 439-442
    • Thompson, T.C.1
  • 168
    • 0031872767 scopus 로고    scopus 로고
    • Elevated expression of caveolin is associated with prostate and breast cancer
    • Yang G., Truong L.D., Timme T.L. et al: Elevated expression of caveolin is associated with prostate and breast cancer. Clin. Cancer Res. 4:1873-1880, 1998.
    • (1998) Clin. Cancer Res , vol.4 , pp. 1873-1880
    • Yang, G.1    Truong, L.D.2    Timme, T.L.3
  • 169
    • 34247507599 scopus 로고    scopus 로고
    • Association of a CAV-1 haplotype to familial aggressive prostate cancer
    • Haeusler J., Hoegel J., Bachmann N., et al: Association of a CAV-1 haplotype to familial aggressive prostate cancer. Prostate 63:369-84, 2005.
    • (2005) Prostate , vol.63 , pp. 369-384
    • Haeusler, J.1    Hoegel, J.2    Bachmann, N.3
  • 170
    • 0033571471 scopus 로고    scopus 로고
    • Caveolin-1 expression in clinically confined human prostate cancer: A novel prognostic marker
    • Yang G., Truong L.D., Wheeler T.M., Thompson T.C.: Caveolin-1 expression in clinically confined human prostate cancer: a novel prognostic marker. Cancer Res. 59:5719-5723, 1999.
    • (1999) Cancer Res , vol.59 , pp. 5719-5723
    • Yang, G.1    Truong, L.D.2    Wheeler, T.M.3    Thompson, T.C.4
  • 171
    • 12444333159 scopus 로고    scopus 로고
    • Development of an immunoassay for serum caveolin-1: A novel biomarker for prostate cancer
    • Tahir S.A., Ren C., Timme T.L. et al: Development of an immunoassay for serum caveolin-1: a novel biomarker for prostate cancer. Clin. Cancer Res. 9:3653-3659, 2003.
    • (2003) Clin. Cancer Res , vol.9 , pp. 3653-3659
    • Tahir, S.A.1    Ren, C.2    Timme, T.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.