Loss of expression of transforming growth factor β type I and type II receptors correlates with tumor grade in human prostate cancer tissues

Clinical Cancer Research

Volumn 2, Issue 8, 1996, Pages 1255-1261

  Kim, Isaac Yi ^a   Ahn, Han Jong ^b   Zelner, David J ^a   Shaw, Jennifer W ^a   Lang, Sharon ^a   Kato, Mitsuyasu ^c   Oefelein, Michael G ^a   Miyazono, Kohei ^c   Nemeth, Jeffrey A ^a   Kozlowski, James M ^a   Lee, Chung ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b University of Ulsan College of Medicine   (South Korea)

^c CANCER INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANGIOGENESIS; ARTICLE; CANCER GRADING; CANCER GROWTH; CELL GROWTH; CELL PROLIFERATION; EPITHELIUM CELL; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROSTATE CANCER; SIGNAL TRANSDUCTION;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; ANTIBODY SPECIFICITY; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; RABBITS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 9544242713     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Wingo, P. A., Tong, T., and Bolden, S. Cancer statistics. CA Cancer J. Clin., 45: 8-30, 1995.
2. Wilding, G. Response of prostate cancer cells to peptide growth factors: transforming growth factor-β. Cancer Surv., 11: 147-163, 1991.
3. Yang, E. Y., and Moses, H. L. Transforming growth factor β1-induced changes on cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane. J. Cell Biol., 111: 731-741, 1990.
4. Roberts, A. B., Sporn, M. B., Assoian, R. K., Smith, J. M., Roche, N. S., Wakefield, L. M., Heine, U. I., Liotta, L. A., Falanga, V., Kehrl, J. H., and Fauci, A. S. Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl. Acad. Sci. USA, 83: 4167-4171, 1986.
5. Kulkarni, A. B., Huh, C. G., Becker, D., Geiser, A., Lyght, M., Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M., and Karlsson, S. Transforming growth factor β1 mull mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA, 90: 770-774, 1993.
6. Wilding, G., Zugmeier, G., Knabbe, C., Flanders, K., and Gelmann, E. Differential effects of transforming growth factor-β on human prostate cancer cells in vitro. Mol. Cell. Endocrinol., 62: 79-87, 1989.
7. Goldstein, D., O'Leary, M., Mitchen, J., Borden, E. C., and Wilding, G. Effects of interferon beta ser and transforming growth factor beta on prostatic cell lines. J. Urol., 146: 1173-1177.
8. Thompson, T. C., Truong, L. D., Timme, T. L, Kadmon, D., McCune, B. K., Flanders, K. C., Scardino, P. T., and Park, S. H. Transgenic models for the study of prostate cancer. Cancer (Phila.), 71: 1165-1171, 1993.
9. Truong, L. D., Kadmon, D., McCuno, B. K., Flanders, K. C., Scardino, P. T., and Thompson, T. C. Association of transforming growth factor-β1 with prostate cancer: an immunohistochemical study. Hum. Pathol., 24: 4-9, 1993.
10. Eastham, J. A., Truong, L. D., Rogers, E., Kattan, M., Flanders, K. C., Scardino, P. T., and Thompson, T. C. Transforming growth factor-β1: comparative immunohistochemical localization in human primary and metastatic prostate cancer. Lab. Invest., 73: 628-635, 1995.
11. Chang, H. L., Gillett, N., Figari, I., Lopez, A. R., Palladino, M. A., and Derynck, R. Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells. Cancer Res., 53: 4391-4398, 1993.
12. Arrick, B. A., Lopez, A. R., Elfman, F., Ebner, R., Damsky, C. H., and Derynck, R. Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1 J. Cell Biol., 118: 715-726, 1992.
13. Steiner, M., and Barrack, E. R. Transforming growth factor-β1 overproduction in prostate cancer: effects on growth in vivo and in vitro. Mol. Endocrinol., 6: 15-25, 1992.
14. Park, K., Kim, S. J., Bang, Y. J., Park, J. G., Kim, N. K., Roberts, A. B., and Sporn, M. B. Genetic changes in the transforming growth factor β(TGF-β) type II receptor gene in human gastric cancer cell: correlation with sensitivity to growth inhibition by TGF-β. Proc. Natl. Acad. Sci. USA, 91: 8772-8776, 1994.
15. Markowitz, S., Wang, J., Meyeroff, L., Parsons, R., Sun, L., Lutterbaugh, J., Fan, R. S., Zborowska, E., Kinzler, K. W., Vogelstein, B., Brattain, M., and Willson, J. K. V. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science (Washington DC), 268: 1336-1338, 1995.
16. Wang, J., Sun, L. Z., Meyeroff, L., Wang, X., Gentry, L. E., Yang, J., Liang, J., Zborowska, E., Markowitz, S., Willson, J. K. V., and Brattain, M. G. Demonstration that mutation of type II TGF-β receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cell. J. Biol. Chem., 220: 22044-22049, 1995.
17. Garrigue-Antar, L., Munoz-Antonia, T., Antonia, S. J., Gesmonde, J., Vellucci, V. F., and Reiss, M. Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells. Cancer Res., 55: 3982-3987, 1995.
18. Lopez-Casillas, F., Cheifetz, S., Doody, J., Andres, J. L., Lane, W. S., and Massague, J. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor. Cell, 67: 785-795, 1991.
19. Franzen, P., ten Dijke, P., Ichijo, H., Yamashita, H., Schulz, P., Heldin, C., and Miyazono, K. Cloning of a TGF-β type I receptor that forms a heteromeric complex with the TGF-β type II receptor. Cell, 75: 681-692, 1994.
20. Lin, H. Y., Wang, X., Ng-Eaton, E., Weinberg, R. A., and Lodish, H. F. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell, 68: 775-785, 1992.
21. Chen, F., and Weinberg, R. A. Biochemical cvidence for the autophosphorylation and transphosphorylation of transforming growth factor β receptor kinases. Proc. Natl. Acad. Sci. USA. 92: 1565-1569, 1995.
22. Wrana, J. L., Attisano, L , Wieser, R., Ventura, F., and Massague, J. Mechanism of activation of the TGF-β receptor. Nature (Lond.), 370: 341-347, 1994.
23. Kim, I. Y., Ahn, H-J., Zelner, D. J., Shaw, J. W., Sensibar, J. A., Kim, J-H., Kato, M., and Lee, C. Genetic change in transforming growth factor-β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells. Cancer Res., 56: 44-48, 1996.
24. Gleason, P. F., Mellinger, G., and the Veterans Administration Cooperative Urological Research Group. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. J Urol., 111: 58-64, 1974.
25. Gullick, W. J., Downward, J., and Waterfield, M. D. Antibodies to the autophosphorylation sites of the epidermal growth factor receptor protein-tyrosine kinase as probes of structure and function. EMBO J., 4: 2869-2877, 1985.
26. Waltenberger, J., Wanders, A., Fellstrom, B., Miyazono, K., Heldin, C-H., and Puna, K. Induction of transforming growth factor-β during cardiac allograft rejection. J. Immunol., 151: 1147-1157, 1993.
27. Yamada, N., Kato, M., Yamashita, H., Nister, M., Miyazono, K., Heldin, C-H., and Funa, K. Enhanced expression of transforming growth factor-β and its type I and type II receptors in human glioblastoma tissues. Int. J. Cancer, 62: 386-392, 1995.
28. Iseki, S., Osumi-Yamashita, N., Miyazono, K., Franzen, P., Ichijo, H., Ohtani, H., Hayashi, Y., and Eto, K. Localization of transforming growth factor-β type I and type II receptors in mouse development. Exp. Cell Res., 219: 339-347, 1995.
29. Kim, I. Y., Ahn, H-J., Zelner, D., Park, L., Sensibar, J. A., and Lee, C. Expression and localization of transforming growth factor-β receptors type I and type II in the rat ventral prostate during regression. Mol. Endocrinol., 10: 107-115, 1996.
30. Nemeth, J. A., Sensibar, J A., and Lee, C. Changes in TGF-β localization in the rat prostatic ductal system during castration-induced regression (Abstract P1-361). 77th Annual Meeting for the Endocrine Society. Washington, DC, June 14-17, 1995.
31. Seemayer, T. A., and Cavenee, W. K. Biology of disease: molecular mechanism of oncogenesis. Lab. Invest., 60: 585-599, 1989.