Androgen receptor expression in prostatic intraepithelial neoplasia and cancer

Journal of Urology

Volumn 161, Issue 4, 1999, Pages 1229-1232

  Sweat, Susan D ^a   Pacelli, Anna ^a   Bergstralh, Erik J ^a   Slezak, Jeffrey M ^a   Bostwick, David G ^a  

^a MAYO CLINIC   (United States)

Author keywords

Androgen; Neoplasia; Prostatic intraepithelial; Prostatic neoplasms; Receptors

Indexed keywords

ANDROGEN RECEPTOR;

ARTICLE; BONE SCINTISCANNING; CANCER GROWTH; CANCER SURVIVAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATE EPITHELIUM; PROSTATECTOMY; PROSTATIC INTRAEPITHELIAL NEOPLASIA; SCORING SYSTEM;

EID: 0032835660     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)61644-6     Document Type: Article

References (19)

1. Van der Kwast, T. and Tetu, B.: Androgen receptors in untreated and treated prostatic intraepithelial neoplasia. Eur. Urol., 30: 265, 1996.
2. Trapman, J. and Brinkmann, A. O.: The androgen receptor in prostate cancer. Path. Res. Pract., 192: 752, 1996.
3. Sadi, M. V., Walsh, P. C. and Barrack, E. R.: Immunohistochemical study of androgen receptors in metastatic prostate cancer. Cancer, 67: 3057, 1991.
4. Sadi, M. V. and Barrack, E. R.: Image analysis of androgen receptor immunostaining in metastatic prostate cancer. Cancer, 71: 2574, 1993.
5. Takeda, H., Akakura, K., Masai, M., Akimoto, S., Yatani, R. and Shimazaki, J.: Androgen receptor content of prostate carcinoma cells estimated by immunohistochemistry is related to prognosis of patients with stage D2 prostate carcinoma. Cancer, 77: 934, 1996.
6. Pertschuk, L. P., Macchia, R. J., Feldman, J. G., Brady, K. A., Levine, M., Kim, D. S., Eisenberg, K. B., Rainford, E., Prins, G. S. and Greene, G. L.: Immunocytochemical assay for androgen receptors in prostate cancer: a prospective study of 63 cases with long-term follow-up. Ann. Surg. Oncol., 1: 495, 1994.
7. Pertschuk, L. P., Schaeffer, H., Feldman, J. G., Macchia, R. J., Kim, Y., Eisenberg, K., Braithwaite, L. V., Axiotis, C. A., Prins, G. and Greene, G. L.: Immunostaining for prostate cancer androgen receptor in paraffin identifies a subset of men with a poor prognosis. Lab. Invest., 73: 302, 1995.
8. Tilley, W. D., Lim-Tio, S. S., Horsfall, D. J., Aspinall, J. O., Marshall, V. R. and Skinner, J. M.: Detection of discrete androgen receptor epitopes in prostate cancer by immunostaining: measurement by color video image analysis. Cancer Res., 54: 4096, 1994.
9. Bostwick, D. G. and Brawer, M. K.: Prostatic intra-epithelial neoplasia and early invasion in prostate cancer. Cancer, 59: 788, 1987.
10. Magi-Galluzzi, C., Xu, X., Hlatky, L., Hahnfeldt, P., Kaplan, I., Hsiao, P., Chang, C. and Loda, M.: Heterogeneity of androgen receptor content in advanced prostate cancer. Mod. Path., 10: 839, 1997.
11. Leav, I., McNeal, J. E., Kwan, P. W.-L., Komminoth, P. and Merk, F. B.: Androgen receptor expression in prostatic dysplasia (prostatic intraepithelial neoplasia) in the human prostate: an immunohistochemical and in situ hybridization study. Prostate, 29: 137, 1996.
12. Klee, G. G., Dodge, L. A., Zincke, H. and Oesterling, J. E.: Measurement of serum prostatic specific antigen using IMX prostate specific antigen assay. J. Urol., 151: 94, 1994.
13. Winkler, H. Z., Rainwater, L. M., Myers, R. P., Farrow, G. M., Therneau, T. M., Zincke, H. and Lieber, M. M.: Stage D1 prostatic adenocarcinoma: significance of nuclear DNA ploidy patterns studies by flow cytometry. Mayo Clin. Proc., 63: 103, 1988.
14. Gettman, M. T., Bergstralh, E. J., Blute, M., Zincke, H. and Bostwick, D. G.: Prediction of patient outcome in pathologic stage T2 adenocarcinoma of the prostate: lack of significance for microvessel density analysis. Urology, 51: 79, 1998.
15. Bostwick, D. G. and Montironi, R.: Evaluating radical prostatectomy specimens: therapeutic and prognostic importance. Virch. Arch., 430: 1, 1997.
16. Bonkoff, H. and Remberger, K.: Widespread distribution of nuclear androgen receptors in the basal cell layer of the normal and hyperplastic human prostate. Virch. Arch. Path. Anat., 422: 35, 1993.
17. Van der Kwast, T. H., Schalken, J., Ruizeveld de Winter, J. A., van Vroonhoven, C. C. J., Mulder, E., Boersma, W. and Trapman, J.: Androgen receptors in endocrine-therapy-resistant human prostate cancer. Int. J. Cancer, 48: 189, 1991.
18. Chodak, G. W., Kranc, D. M., Puy, L. A., Takeda, H., Johnson, K. and Chang, C.: Nuclear localization of androgen receptor in heterogeneous samples of normal, hyperplastic and neoplastic human prostate. J. Urol., 147: 798, 1992.
19. Miyamoto, K. K., McSherry, S. A., Dent, G. A., Sar, M., Wilson, E. M., French, F. S., Sharief, Y. and Mohler, J. L.: Immunohistochemistry of the androgen receptor in human benign and malignant prostate tissue. J. Urol., 149: 1015, 1993.