Telomerase activity: A prevalent marker of malignant human prostate tissue

Cancer Research

Volumn 56, Issue 1, 1996, Pages 218-222

  Sommerfeld, Hans Joerg ^a   Meeker, Alan K ^b   Piatyszek, Mieczyslaw A ^c   Bova, G Steven ^b   Shay, Jerry W ^c   Coffey, Donald S ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b JOHNS HOPKINS HOSPITAL   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; RNA DIRECTED DNA POLYMERASE; TELOMERASE; TISSUE EXTRACT;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA HYBRIDIZATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROSTATECTOMY; TELOMERE;

EID: 0030061426     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Zakian, V. A. Strucrure and function of telomeres. Annu. Rev. Genet., 23: 579-604, 1989.
2. Blackburn, E. H. Structure and function of telomeres. Nature (Lond), 350: 569-573, 1991.
3. Blackburn, E. H., and Szostak, J W. The molecular structure of centromeres and telomeres. Annu. Rev. Biochem., 53: 163-194, 1984.
4. Moyzis, R. K., Buckingham, J. M., Cram, L. S., Dam, M , Deaven, L. L., Jones, M. D., Meyne, J., Ratliff, R. L., and Wu, J. R. A highly conserved repetitive DNA sequence (TTAGGG)n present at the telomeres of human chromosomes. Proc. Natl. Acad Sci. USA, 85: 6622-6626, 1988.
5. deLange, T., Shiue, L., Myers, R. M., Cox, D. R., Naylor, S. L., Killery, A. M., and Varmus, H. E. Structure and variability of human chromosome ends. Mol. Cell Biol. 10. 518-527, 1990.
6. Harley, C. B., Futcher, A B., and Greider, C. W. Telomeres shorten during aging of human fibroblasts. Nature (Lond), 345: 458-460, 1990
7. Hastie, N. D., Dempster, M., Dunlop, M G., Thompson, A. M., Green, D. K., and Allshire, R. C. Telomere reduction in human colorectal carcinoma and with aging. Nature (Lond.), 346; 866-868, 1990.
8. Levy, M Z , Allsopp, R. C , Futcher, A. B., Greider, C W., and Harley, C. B. Telomere end-replication problem and cell aging. J. Mol. Biol., 225: 951-960, 1992.
9. Watson, J. D. Origin of Concatemeric T7 DNA. Nature New Biol., 239. 197-201, 1972.
10. Olovnikov, A. M. A theory of marginotomy. J. Theor. Biol., 41: 181-190, 1973.
11. Harley, C B, Telomere loss: mitotic clock or senetic time bomb? Mutat. Res., 256: 271-282, 1991.
12. Shay, J W., Werbin, H., and Wright, W. E. Telomere shortening may contribute to aging and cancer: a perspective. Mol Cell Diff., 2: 1-21, 1994.
13. Allsopp, R. C., Vaziri, H., Patterson, C., Goldstein, S , Younglai, E V., Futcher, A. B , Greider, C W., and Harley, C B. Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl Acad. Sci. USA, 89: 10114-10118, 1992.
14. Shay, J. W., Pereira-Smith, O. M., and Wright, W. E A role for both RB and p53 in the regulation of human cellular senescence. Exp. Cell Res., 196. 33-39, 1991
15. Shay, J. W., Wright, W., and Werbin, H. Defining the molecular mechanisms of human cell immortalization (review). Biochim. Biophys. Acta, 1072: 1-7, 1991
16. Wright, W , and Shay, J. W Telomere positional effects and the regulation of cellular senescence. Trends Genet., 8: 193-197, 1992.
17. Counter, C. M., Avilion, A. A., LeFeuvre, C. E., Stewart, N. G , Greider, C. W., Harley, C. B., and Bacchetti, S Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J., 11: 1921-1929, 1992.
18. Counter, C. M , Botelho, P., Wang, P., Harley, C. B., and Bacchetti, S. Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B-lymphocytes. J Virol., 68: 3410-3414, 1994
19. Adamson, D. J. A., King, D J., and Haites, N E. Significant telomere shortening in childhood leukemia. Cancer Genet. Cytogenet., 61. 204-205, 1992.
20. Smith, J. K. and Yeh, G. Telomere reduction in endometrial adenocarcinoma. Am. J. Obstet. Gynecol., 167: 1883-1887, 1992.
21. Hiyama, E., Hiyama, K , Yokoyama, T., Ichikawa, T., and Matsuura, Y Length of telomeric repeals in neuroblastoma, correlation with prognosis and other biological characteristics. Jpn. J. Cancer Res., 83: 159-164, 1992
22. Mehle, C., Ljungberg, B., and Roos, G. Telomere shortening in renal cell carcinoma. Cancer Res , 54. 236-241, 1994
23. Counter, C. M., Hirte, H W., Bacchetti, S , and Harley, C. B. Telomerase activity in human ovarian carcinoma. Proc. Natl. Acad. Sci. USA, 91. 2900-2904, 1994.
24. Morin, G. B, The human telomere terminal transferase is a ribonuclear protein that synthesizes TTAGGG repeat. Cell. 59: 521-529, 1989.
25. Greider, C W., and Blackburn, E. H. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell, 43: 405-412, 1985
26. Greider, C W. Telomeres, telomerase and senescence. Bioessays, 12: 363-369, 1990
27. Kim, N W., Piatyszek, M. A., Prowse, K. R , Harley, C. B., West, M. D., Ho, P. L., Coviello, G. M., Wright, W. E., Weinrich, S. L., and Shay, J. W Specific association of human telomerase activity with immortalized cells and cancer. Science (Washington DC), 260: 2011-2015.
28. Hiyama, E , Hiyama, K., Yokoyama, T., Matsuura, Y., Piatyszek, M A., and Shay, J. W Correlating telomerase activity levels with human neuroblastoma outcomes. Nat Med., 1: 249-257, 1995
29. Hiyama, E , Hiyama, K., Ishioka, S , Yamakido, M., Inai, K., Gazdar, A. F., Piatyszek, M. A., and Shay, J. W. Telomerase activity in small-ceil and non-small-cell lung cancers. J. Natl. Cancer Inst., 87. 895-902, 1995.
30. Tahara, H., Nakanishi, T., Kitamoto, M., Nakashio, R. Shay, J. W., Tahara, E., Kajiyama, G., and Ide, T Telomerase activity in human liver tissue. comparison between chrome liver disease and hepatocellular carcinomas. Cancer Res., 55: 2734-2736, 1995
31. Hiyama, E., Yokoyama, T., Tatsumoto, N., Hiyama, K., Imamura, Y., Murakami, Y., Kodama, T., Piatyszek, M, A., Shay, J. W., and Matsuura, Y. Telomerase activity in gastric cancer Cancer Res , 55 3258-3262, 1995.
32. Stone, K. R., Mickey, D. D., Wunderli, H., Mickey, G., and Paulson, D. F. Isolation of a human prostate carcinoma cell line (DU145) Int. J. Cancer., 21: 274-281, 1978
33. Horoszewicz, J. S., Leong, S. S., Kawinski, E , Karr, J. P., Rosenthal, H., Chu, T. M., Mirand, E. A., and Murphy, G. P. LNCaP model of human prostatic carcinoma Cancer Res., 43: 1809-1818, 1983.
34. Kaighn, M. E , Narayan, K S., Ohnuki, Y., Lechner, J. F , and Jones, L. W. Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest. Urol., 17: 16-23, 1979.
35. Gingrich, J. R., Tucker, J. A., Walther, P. J , Day, J. W , Poulton, S. H., and Webb, K. S. Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1). J. Urol , 146: 915-919, 1991.
36. Iizumi, T., Yazaki, T., Kanon, S , Kondo, I., and Koiso, K. Establishment of a new prostatic carcinoma cell line (TSU-Pr1). J. Urol., 137: 1304-1306, 1987.
37. Vazin, H., Schachter, F , Uchida, I., Wei, L , Zhu, X., Effros, R., Cohen, D., and Harley, C. B. Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J. Hum Genet. 52 661-667, 1993
38. Piatyszek, M A., Kim, N W., Weinrich, S L., Hiyama, K., Hiyama, E., Wright, W. E., and Shay, J. W Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP). Methods Cell Sci., in press, 1996
39. Armitage, P., and Doll, R. The age distribution of cancer and a multi-stage theory of carcinogenesis Br. J Cancer., 8. 1-12, 1954.
40. Ashley, D. J. B On the incidence Ot carcinoma of the prostate J. Pathol. Bacteriol., 90: 217-224, 1965.
41. Rinker-Schaeffer, C. W , Partin, A W., Isaacs, W. B , Coffey, D S., and Isaacs, J. T. Molecular and cellular changes associated with the acquisition of metastatic ability by prostate cancer cells Prostate, 25: 249-265, 1994.