Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping

Cancer Research

Volumn 56, Issue 13, 1996, Pages 3091-3102

  Cher, Michael L ^a,c   Bova, G Steven ^b   Moore, Dan H ^a   Small, Eric J ^a   Carroll, Peter R ^a   Pin, Sokhom S ^b   Epstein, Jonathan I ^b   Isaacs, William B ^b   Jensen, Ronald H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; DNA;

ADULT; AGED; ALLELE; ARTICLE; BONE METASTASIS; CANCER GROWTH; CANCER HORMONE THERAPY; CANCER RECURRENCE; CHROMOSOME ABERRATION; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HYBRIDIZATION; LYMPH NODE METASTASIS; MALE; METASTASIS; NEGRO; PRIORITY JOURNAL; PROSTATE CANCER; SOUTHERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; ANDROGENS; BLOTTING, SOUTHERN; BONE NEOPLASMS; CHROMOSOME ABERRATIONS; DNA, NEOPLASM; GENOME, HUMAN; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASMS, HORMONE-DEPENDENT; NUCLEIC ACID HYBRIDIZATION; PROSTATIC NEOPLASMS; REPRODUCIBILITY OF RESULTS;

EID: 0029997010     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Friend, S. H., Bernards, R , Rogelj, S., Weinberg, R. A., Rapaport, J. M., Albert, D M., and Dryja, T. P. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature (Lond.), 323: 643-646, 1986.
2. Cawthon, R. M., Weiss, R., Gangfeng, X., Viskochil, D., Culver, M., Stevens, J , Robertson, M., Dunn, D., Gesterland, R., O'Connell, P., and White, R. A major segment of the neurofibromatosis type 1 gene cDNA sequence, genomic structure, and point mutations [Published erratum appears in Cell 1990 Aug 10;62: after p. 608]. Cell, 62: 193-201, 1990
3. Baker, S. J., Fearon, E. R., Nigro, J. M , Hamilton, S. R., Preisinger, A. C , Jessup, J. M , vanTuinen, P., Ledbetter, D H., Barker, D. F., Nakamura, Y , White, R., and Vogelstein, B. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (Washington DC), 244: 217-221, 1989.
4. Shuin, T , Kondo, K , Torigoe, S , Kishida, T., Kubota, Y., Hosaka, M., Nagashima, Y , Kitamura, H., Latif, F., Zbar, B., Lerman, M. I , and Yao, M. Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas. Cancer Res , 54: 2852-2855, 1994.
5. Visakorpi, T., Hyytinen, E , Koivisto, P., Tanner, M., Kemanen, R , Palmberg, C., Palotie, A , Tammela, T., Isola, J., and Kalhomemi, O-P. In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat. Genet., 9: 401-406, 1995.
6. Jen, J , Kim, H., Piamadosi, S., Liu, Z F., Levitt, R. C., Sistonen, P , Kinzler, K. W., Vogelstein, B., and Hamilton, S. R Allelic loss of chromosome 18q and prognosis in colorectal cancer. N. Engl. J Med. 311: 213-221, 1994.
7. Grundy, P. E., Telzerow, P. E., Breslow, N., Moksness, J., Huff, V , and Paterson, M C. Loss of heterozygosity for chromosomes 16q and 1p in Wilms' tumors predicts an adverse outcome. Cancer Res., 54. 2331-2333, 1994.
8. Carter, B. S , Ewing, C M., Ward, W. S., Treiger, B F., Aalders, T. W., Schalken, J A., Epstein, J. I., and Isaacs, W. B Allelic loss of chromosomes 16q and 10q in human prostate cancer Proc Natl Acad. Sci. USA, 87: 8751-8755, 1990.
9. Kunimi, K., Bergerheim, U S , Larsson, I. L., Ekman, P , and Collins, V. P. Allelotyping of human prostatic adenocarcinoma. Genomics, 11: 530-536, 1991.
10. Bova, G. S., Carter, B. S., Bussemakers, M. J., Emi, M., Fujiwara, Y., Kyprianou, N., Jacobs, S. C., Robinson, J C , Epstein, J I , Walsh, P. C., and Isaacs, W. B Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer Cancer Res , 53: 3869-3873, 1993.
11. MacGrogan, D., Levy, A., Bosiwick, D , Wagner, M., Wells, D., and Bookstein, R Loss of chromosome 8p loci in prostate cancer mapping by quantitative allelic imbalance. Genes Chromosomes & Cancer, 10. 151-159, 1994.
12. Bergerheim, U. S., Kunimi, K , Collins, V. P., and Ekman, P. Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma. Genes Chromosomes & Cancer, 3 215-220, 1991
13. Chang, M , Tsuchiya, K , Batchelor, R. H , Rabinovitch, P. S., Kulander, B. G., Haggitt, R C , and Burmer, G C Deletion mapping of chromosome 8p in colorectal carcinoma and dysplasia arising in ulcerative colitis, prostatic carcinoma, and malignant fibrous histiocytomas Am. J Pathol , 144 1-6, 1994.
14. Trapman, J., Sleddens, H. F., vanderWeiden, M. M., Dinjens, W N., Konig, J J., Schroder, F. H , Faber, P. W., and Bosman, F. T. Loss of heterozygosity of chromosome 8 microsatellite loci implicates a candidate tumor suppressor gene between the loci D8S87 and D8S133 in human prostate cancer. Cancer Res., 54: 6061-6064, 1994.
15. Suzuki, H., Emi, M., Komiya, A , Fujiwara, Y., Yatani, R , Nakamura, Y , and Shimazata, J. Localization of a tumor suppressor gene associated with progression of human prostate cancer within a 1 2 mb region of 8p22-p213 Genes Chromosomes & Cancer, 13: 168-174, 1995
16. Cher, M. L., Ito, T., Weidner, N., Carroll, P R , and Jensen, R. H. Mapping of regions of physical deletion on chromosome 16q in prostate cancer cells by fluorescence in situ hybridization (FISH). J Urol., 153: 249-254, 1995
17. Phillips, S. M , Morton, D G., Lee, S. J., Wallace, D. M., and Neoptolemos, J. P. Loss of heterozygosity of the retinoblastoma and adenomatous polyposis susceptibility gene loci and in chromosomes 10p, 10q and 16q in human prostate cancer. Br. J. Urol. 73, 390-395, 1994
18. Sakr, W. A., Macoska, J A , Benson, P., Grignon, D. J., Wolman, S. R , Pontes, J. E., and Crissman, J D. Allelic loss in locally metastatic, multisampled prostate cancer. Cancer Res., 54: 3273-3277, 1994.
19. Latil, A , Baron, J. C., Cussenot, O , Fournier, G , Sousst, T., Boccon, G. L., Le, D. A., Rouesse, J., and Lidereau, R. Genetic alterations in localized prostate cancer identification of a common region of deletion on chromosome arm 18q. Genes Chromosomes & Cancer, 11: 119-125, 1994.
20. Massenkeil, G., Oberhuber, H., Hailemariam, S., Sulser, T , Diener, P A , Bannwart, F., Schafer, R., and Schwane, W I. P53 mutations and loss of heterozygosity on chromosomes 8p, 16q, 17p, and 18q are confined to advanced prostate cancer. Anticancer Res., 14: 2785-2790, 1994.
21. Kallioniemi, A , Kallioniemi, O. P., Sudar, D., Rutovitz, D , Gray, J. W., Waldman, F., and Pinkel, D. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science (Washington DC), 258 818-821, 1992.
22. Cher, M. L., MacGrogan, D., Bookstein, R , Brown, J. A., Jenkins, R. B., and Jensen, R. H. Comparative genomic hybridization, allelic imbalance, and FISH on chromosome & in prostate cancer Genes Chromosomes & Cancer, 11: 153-162, 1994.
23. Visakorpi, T., Kallioniemi, A H., Syvanen, A., Hyyunen, E. R., Karhu, R., Tammela, T., Isola, J. J., and Kallioniemi, O-P. Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization. Cancer Res., 55: 342-347, 1995
24. Gleason, D. F. Classification of prostatic carcinomas Cancer Chemother. Rep., 50: 125-128, 1966
25. Kallioniemi, O. P , Kallioniemi, A , Piper, J., Isola, J., Waldman, F M , Gray, J. W., and Pinkel, D. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors. Genes Chromosomes & Cancer, 10: 231-243, 1994.
26. Morton, N. E. Parameters of the human genome. Proc. Natl. Acad. Sci. USA, 83: 7474-7476, 1991.
27. Lucas, J. N., and Gray, J. W. Centromeric index versus DNA content flow karyotypes of human chromosomes measured by means of slit-scan flow cytometry. Cytometry, 8 273-279, 1987.
28. Moore, D H. I., Cher, M L , and Gray, J. W. A t-statistic for objective interpretation of comparative genomic hybridization (CGH) profiles. Cytometry, in press, 1996.
29. Weissenbach, J., Gyapay, G., Dib, C., Vignal, A., Morissette, J., Millasseau, P , Vaysseix, G., and Lathrop, M. A second-generation linkage map of the human genome. Nature (Lond.), 359: 794-801, 1992.
30. Cohen, J. A coefficient of agreement for nominal scales. Educ. Psychol. Meas., 20: 37-46, 1960.
31. Dhom, G. Epidemiologic aspects of latent and clinically manifest carcinoma of the prostate. J. Cancer Res. Clin Oncol , 106: 210-218, 1983
32. Stephenson, R. A., James, B. C., Gay, H., Fair, W. R., Whitmore, W J., and Melamed, M. R. Flow cytometry of prostate cancer relationship of DNA content to survival. Cancer Res , 47: 2504-2507, 1987
33. Kallioniemi, A., Kallioniemi, O. P., Piper, J , Tanner, M , Stokke, T., Chen, L., Smith, H. S , Pinkel, D , Gray, J. W., and Waldman, F M. Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc Natl. Acad. Sci. USA. 91: 2156-2160, 1994.
34. Van Den Berg, C., Guan, X , Von Hoff, D., Jenkins, R , Bittner, M , Griffin, C., Kallioniemi, O., Visakorpi, T., McGill, J., Herath, J., Epstein, J., Sarosdy, M., Meltzer, P , and Trent, J. DNA sequence amplification in human prostate cancer identified by chromosome microdissection: potential prognostic implications. Clin. Cancer Res., 1 11-18, 1995
35. Brothman, A R , Peehl, D M , Patel, A. M., and McNeal, J. E. Frequency and pattern of karyotypic abnormalities in human prostate cancer. Cancer Res., 50: 3795-3803, 1990
36. Bookstein, R., MacGrogan, D., Hilsenbeck, S. G , Sharkey, F., and Allred, D C p53 is mutated in a subset of advanced-stage prostate cancers. Cancer Res., 53. 3369-3373, 1993
37. Aprikian, A. G., Sarkis, A. S., Farr, W. R , Zhang, Z. F., Fuks, Z , and Cordon-Cardo, C. Immunohistochemical determination of p53 protein nuclear accumulation in prostatic adenocarcinoma J Urol., 151: 1276-1280, 1994
38. Isaacs, W. B , Carter, B. S , and Ewing, C. M Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles. Cancer Res., 51: 4716-4720, 1991
39. Eagle, L R., Yin, X , Brothman, A R , Williams, B I., Atkin, N. B., and Prochownik, E. V. Mutation of the MX11 gene in prostate cancer Nat Genet., 9. 249-255, 1995.
40. Zervos, A. S., Gyuris, J., and Brent, R. MxiI, a protein that specifically interacts with Max to bind Myc-Max recognition sites. Cell, 72. 223-232, 1993.
41. Furukawa, Y., Nakatsuru, S., Nagafuchi, A., Tsukita, S , Muto, T., Nakamura, Y , and Horn, A. Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) αI gene (CTNNA1). Cytogenet Cell Genet., 65, 74-78, 1994.
42. Morton, R. A., Ewing, C. M , Nagafuchi, A , Tsukita, S., and Isaacs, W. B. Reduction of E-cadherin levels and deletion of the α-catenin gene in human prostate cancer cells. Cancer Res , 53: 3585-3590, 1993.
43. Bookstein, R., Rio, P., Madreperla, S A , Hong, F., Allred, C., Grizzle, W. E., and Lee, W H. Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma. Proc. Natl. Acad. Sci. USA, 87, 7762-7766, 1990
44. Brooks, J. D., Bova, G. S., and Isaacs, W. B Allelic loss of the retinoblastoma gene in primary human prostatic adenocarcinomas. Prostate, 26 35-39, 1995.
45. Umbas, R., Isaacs, W B , Bringuier, P. P., Schaafsma, H. E., Karthaus, H. F., Oosterhof, G. O., Debruyne, F. M., and Schalken, J. A Decreased E-cadherin expression is associated with poor prognosis in patients with prostate cancer Cancer Res., 54: 3929-3933, 1994.
46. Umbas, R., Schalken, J. A., Aalders, T. W , Carter, B. S., Kalthaus, H. F., Schaafsma, H. E., Debruyne, F M., and Isaacs, W B Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. Cancer Res., 52: 5104-5109, 1992.
47. Matsuyama, H., Pan, Y , Skoog, L., Tribukait, B , Naito, K., Ekman, P., Lichter, P., and Bergerheim, U. S. Deletion mapping of chromosome 8p in prostate cancer by fluorescence in situ hybridization. Oncogene, 9: 3071-3076, 1994.
48. Bandyk, M G., Zhao, L., Troncoso, P., Pisters, L. L., Palmer, J. L., von Eschenbach, A. C., Chung, L. W., and Liang, J. C. Trisomy 7: a potential cytogenetic marker of human prostate cancer progression. Genes Chromosomes & Cancer, 9: 19-27, 1994.
49. Alcaraz, A., Takahashi, S., Brown, J A., Herath, J. F., Bergstralh, E. J., Larson, K. J , Lieber, M. M., and Jenkins, R. B Aneuploidy and aneusomy of chromosome 7 detected by fluorescence in situ hybridization are markers of poor prognosis in prostate cancer. Cancer Res., 54: 3998-4002, 1994.
50. Pisters, L L , Troncoso, P., Zhau, H. E., Li, W , von, E. A , and Chung, L. W. c-met proto-oncogene expression in benign and malignant human prostate tissues. J. Urol., 154: 293-298, 1995.
51. Gao, X., Zacharek, A., Salkowski, A., Grignon, D J , Sakr, W., Porter, A. T., and Honn, K. V. Loss of heterozygosity of the BKCA1 and other loci on chromosome 17q in human prostate cancer. Cancer Res., 55: 1002-1005, 1995
52. Kuhn, E. J , Kumot, R. A., Sesterhenn, I A , Chang, E H., and Moul, J. W. Expression of the c-erbB-2 (HER-2/neu) oncoprotein in human prostatic carcinoma (Review) J Urol., 150; 1427-1433, 1993.
53. Pienta, K. J., Demers, R., Hoff, M., Kau, T. Y., Montie, J. E., and Severson, R. K Effect of age and race on the survival of men with prostate cancer in the Metropolitan Detroit tricounty area, 1973 to 1987. Urology, 45: 93-102, 1995.
54. Brawn, P. N., Johnson, E. H., Kuhl, D L., Riggs, M. W., Speights, V. O , Johnson, C. F., Pandya, P. P., Lind, M. L , and Bell, N. F. Stage at presentation and survival of white and black patients with prostate carcinoma. Cancer (Phila.), 71: 2569-2573, 1993.