The cadherin cell-cell adhesion pathway in prostate cancer progression

British Journal of Urology

Volumn 79, Issue SUPPL. 1, 1997, Pages 37-43

  Paul, R ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; CADHERIN; CATENIN; CELL ADHESION MOLECULE; P CADHERIN; TUMOR MARKER; UNCLASSIFIED DRUG; UVOMORULIN;

BASAL CELL; CANCER GRADING; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CELL ADHESION; CELL AGGREGATION; CELL FUNCTION; CONFERENCE PAPER; DISEASE COURSE; GENE DELETION; GENE TRANSFER; HETEROZYGOSITY LOSS; HUMAN; MALE; METASTASIS; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROSTATECTOMY; PROTEIN EXPRESSION;

BETA CATENIN; CADHERINS; CELL ADHESION; CYTOSKELETAL PROTEINS; DISEASE PROGRESSION; DNA METHYLATION; HUMANS; MALE; PROSTATE; PROSTATIC NEOPLASMS; TRANS-ACTIVATORS;

EID: 0031397808     PISSN: 00071331     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1464-410x.1997.tb00799.x     Document Type: Article

References (48)

1. Hynes RO. Integrins, a family of cell surface receptors. Cell 1987; 48: 549-55
2. Williams AF, Barclay AN. The immunoglobulin superfamily domains for cell surface recognition. Ann Rev Immunol 1988; 6: 381-405
3. Takeichi M. Cell-cell adhesion molecules controlling animal morphogenesis. Development 1988; 102: 639-55
4. Nose A, Tsuji K, Takeichi M. Localisation of specificity determining sites in cadherin cell adhesion molecules. Cell 1990; 61: 147-55
5. Takeichi M. Cadherins: A molecular family important in selective cell-cell adhesion. Annu Rev Biochem 1990; 59: 237-52
6. Nose A, Nagafuchi A, Takeichi M. Expressed recombinant cadherins mediate cell sorting in model systems. Cell 1988; 54: 993-1001
7. Ozawa M, Kemler R. Molecular organisation of the uvomorulin-catenin complex. J Cell Biol 1992; 116: 989-96
8. Nagafuchi A, Takeichi M. Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J 1988; 7: 3679-84
9. Behrens J, Mareel MM, Van Roy FM, Birchmeier W. Dissecting tumor cell invasion: Epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion. J Cell Biol 1989; 108: 2435-47
10. Thomson RB, Igarashi P, Biemesderfer D et al. Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family. J Biol Chem 1995:270: 17594-601
11. Shimoyama Y, Gotoh M, Terasaki T, Kitajima M. Hirohashi S. Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells. Cancer Res 1995; 55:2206-11
12. Sakaki T, Wato M, Kaji R, Mushimoto K, Shirasu R, Tanaka A. Correlation of E- and P-cadherin expression with differentiation grade and mode of invasion in gingival carcinoma. Pathol Int 1994; 44: 280-6
13. Nose A, Takeichi M. A novel cadherin cell adhesion molecule: its expression patterns associated with implantation and organogenesis of mouse embryos. J Cell Biol 1986; 103: 2649-58
14. Shimoyama Y, Hirohashi S, Hirano S et al. Cadherin cell adhesion molecules in human epithelial tissues and carcinomas. Cancer Res 1989; 49: 2128-33
15. Vleminckx K, Vakaet L, Mareel M, Fiers W, VanRoy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991; 66: 107-19
16. Watabe M, Nagafuchi A, Tsukita S, Takeichi M. Induction of polarised cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J Cell Biol 1994; 127: 247-56
17. Byers SW, Sommers CL, Hoxter B, Mercurio AM, Tozeren A. Role of E-cadherin in the response of tumor cell aggregates to lymphatic, venous and arterial flow: measurement of cell-cell adhesion strength. J Cell Sei 1995; 108: 2053-64
18. Shimoyama Y, Hirohashi S. Expression of E- and P-cadherin in gastric carcinomas. Cancer Res 1991; 51: 2185-92
19. Shiozaki H. Tahara H, Oka H et al. Expression of immunoreactive E-cadherin adhesion molecules in human cancers. Am J Path 1991; 139: 17-23
20. Mayer B, Johnson JP, Leitl F et al. E-cadherin expression in primary and metastatic gastric cancer. Down-regulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res 1993; 53: 1690-5
21. Oka H, Shiozaki H, Kobayashi K et al. Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res 1993; 53: 1696-701
22. Palacios J, Benito N, Pizarro A et al. Anomalous expression of P-cadherin in breast carcinoma. Correlation with E-cadherin expression and pathological features. Am J Path 1995; 146: 605-12
23. Rasbridge SA, Cillett CE, Sampson SA, Walsh FS, Millis RR. Epithelial (E-) and placental (P-) cadherin cell adhesion molecule expression in breast carcinoma. J Path 1993; 169: 245-50
24. Shinoura N, Paradies NE, Warnick RE et al. Expression of N-cadherin and α-catenin in astrocytomas and glioblastomas. Br J Cancer 1995; 72: 627-33
25. Tani T, Laitinen L, Kangas L, Lehto V-P, Virtanen I. Expression of E- and N-cadherin in renal cell carcinomas, in renal cell carcinoma cell lines in vitro and in their xenografts. Int J Cancer 1995; 64: 407-14
26. Nouwen EJ, Dauwe S, Van der Biest I, De Broe ME. Stageand segment-specific expression of cell adhesion molecules N-CAM. A-CAM and L-CAM in the kidney. Kidney M 1993; 44: 147-58
27. Katagiri A, Watanabe R, Tomita Y. E-cadherin expression in renal cell cancer and its significance in metastasis and survival. Br J Cancer 1995; 71: 376-9
28. Ross JS, del Rosario AD, Figge HL, Sheehan C. Fisher HA, Bui HX. E-cadherin expression in papillary transitional cell carcinoma of the urinary bladder. Hum Pathol 1995; 26: 940-4
29. Lipponen PD, Exkelinen MJ. Reduced expression E-cadherin is related to invasive disease and frequent recurrence in bladder cancer. J Cancer Res Clin Oncol 1995; 121: 303
30. Gagliardi G, Kandemir O, Liu D et al. Changes in E-cadherin immunoreactivity in the adenoma-carcinoma sequence of the large bowel. Virchows Arch 1995; 426: 149
31. Dorudi S, Hanby AM, Pousom R, Northover J, Hart IR. Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome. Br J Cancer 1995: 71: 614
32. Isaacs JT, Barrack ER, Isaacs WB, Coffey DS. The relationship of cellular structure and function: The matrix system. In Murphy GP. Sandberg AA, Karr JP, eds. The Prostate Cell: Structure and Function, Part A. New York: Alan R. Liss, 1981
33. Umbas R, Schalken JA, Aalders TW et al. Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. Cancer Res 1992; 52: 5104-9
34. Carter BS, Ewing CM, Ward WS et al. Allelic loss of chromosomes 16q and lOq in human prostate cancer. Proc Natl Acad Sei USA 1990; 87: 8751-5
35. Natt E, Magenis RE. Zimmer J, Mansouri A, Scherer G. Regional assignment of the human loci for uvomorulin and chymotrypsinogen B with the help of two overlapping deletions on the long arm of chromosome 16. Cytogen Cell Gen 1989; 50: 145
36. Bussernakers MJG, Van Moorselaar RJA, Giroldi LA et al Decreased expression of E-cadherin in the progression of rat prostatic cancer. Cancer Res 1992; 52: 2916-22
37. Umbas R, Isaacs WB, Bringuier PP et al Decreased E-cadherin expression is associated with poor prognosis in patients with prostate cancer. Cancer Res 1994; 54: 3929-33
38. Morton RA, Ewing CM, Nagafuchi A, Tsukita S, Isaacs WB. Reduction of E-cadherin levels and deletion of the alpha-catenin gene in human prostate cancer cells. Cancer Res 1993; 53: 3585-90
39. Ewing CM, Ru N, Morton RA et al. Chromosome 5 supresses tumorigenicity of PC3 prostate cancer cells. Correlation with re-expression of alpha-catenin and restoration of E-cadherin function. Cancer Res 1995; 55: 4813-17
40. Kleinerman DI, Troncoso P, Lin SH et al Consistent expression of an epithelial cell adhesion molecule (C-CAM) during human prostate development and loss of expression in prostate cancer: implication as a tumor suppressor. Cancer Res 1995; 55: 1215-20
41. Wojno KJ, Epstein JI. The utility of basal cell-specific anticytokeratin antibody (34 beta E12) in the diagnosis of prostate cancer. A review of 228 cases. Am J Surg Pathol 1995; 19: 251-60
42. Ewing CM, Isaacs WB, Rhim JS, Bussemaker MJ, Schalken JA. Analysis of a cadherin-6 like molecule found in neonatal and neoplastic but not in the normal adult prostate tissue. J Urol 1996; 155 (Suppl.): 694A
43. Bussemakers MJG, Dikhoff X. van Bokhoven A, Schalken JA. De novo expression of osteoblast (OB) -cadherin/11 in prostate cancer. J Urol 1996; 155 (Suppl.): 351A
44. Candidus S, Bischoff P. Becker K-F, Höfler H. No evidence for mutations in the α- and β-catenin genes in human gastric and breast cancer. Cancer Res 1996: 56: 49-52
45. Jarrard DF. Bova SG, Isaacs WB. DNA methylation, molecular genetic and likage studies in prostate cancer. Prostate 1996: 6 (Suppl.): 36-44
46. Jarrard DF, Ewing CM, Morton RA, Bova GS, Isaacs WB. High levels of de novo methylation at CpG islands are found in the human prostate. J Urol 1995; 153: 344
47. Graff JR, Herman JG, Lapidus RG et al. E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res 1995; 55: 5195-9
48. Yoshiura K, Kanal Y, Ochiai A, Shimovam Y, Sugimura T. Hirohashi S. Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc Natl Acad Sci USA 1995; 92: 7416-19