Increased expression of cyclooxygenase-2 and nitric oxide synthase-2 in human prostate cancer

Urological Research

Volumn 29, Issue 1, 2001, Pages 25-28

  Uotila, Pekka ^a   Valve, Eeva ^a   Martikainen, Paula ^b   Nevalainen, Marja ^a   Nurmi, Martti ^a   Härkönen, Pirkko ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Cyclooxygenase 1; Cyclooxygenase 2; Nitric oxide synthase 2; Prostate cancer; Prostatic intraepithelial neoplasia

Indexed keywords

CYCLOOXYGENASE 2; NITRIC OXIDE SYNTHASE; CYCLOOXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOENZYME; MEMBRANE PROTEIN; MESSENGER RNA; PROSTAGLANDIN SYNTHASE; PTGS1 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN;

ANGIOGENESIS; ARTICLE; CATALYSIS; CELL TRANSFORMATION; ENDOTHELIUM CELL; ENZYME INDUCTION; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; STROMA CELL; TUMOR GROWTH; VASCULAR ENDOTHELIUM; AGED; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROSTATE TUMOR; PROSTATIC INTRAEPITHELIAL NEOPLASIA;

AGED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROSTATIC NEOPLASMS; RNA, MESSENGER;

EID: 0035104125     PISSN: 03005623     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002400000148     Document Type: Article

References (25)

1. The development of human benign prostatic hyperplasia with age
2. High grade prostatic intraepithelial neoplasia. The most likely precursor of prostate cancer
3. Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer
4. Is there a role for nitric oxide in tumor angiogenesis?
5. Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma
6. Inhibition of nitric oxides synthase as a potential therapeutic target
7. The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells
8. Ultraviolet irradiation induces cyclooxygenase-2 expression in keratinocytes
9. Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
10. Selective expression of inducible nitric oxide synthase in human prostate carcinoma
11. Expression of cyclooxygenase-2 (COX-2) in human invasive transitional cell carcinoma (TCC) of the urinary bladder
12. Prolactin and prolaction receptors are expressed and functioning in human prostate
13. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
14. Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis
15. Expression of cyclooxygenase-2 in human gastric carcinoma
16. Expression of cyclooxygenase-1 and -2 in human colorectal cancer
17. Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo
18. Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2
19. Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: Studies with 1400 W, a novel inhibitor
20. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
21. Cyclooxygenase regulates angiogenesis induced by colon cancer cells
22. Cyclooxygenase-2 expression in human monocytes stimulated by meconium
23. Cyclooxygenases 1 and 2
24. Expression of cyclo-oxygenase-2 in human lung cancer
25. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis