Analysis of 6912 unselected somatic hypermutations in human VDJ rearrangements reveals lack of strand specificity and correlation between phase II substitution rates and distance to the nearest 3′ activation-induced cytidine deaminase target

Journal of Immunology

Volumn 178, Issue 7, 2007, Pages 4322-4334

  Ohm Laursen, Line ^a,b   Barington, Torben ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; CYTIDINE; CYTIDINE DEAMINASE; IMMUNOGLOBULIN HEAVY CHAIN; NUCLEOTIDE; URACIL;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DEAMINATION; GENE FREQUENCY; GENE REARRANGEMENT; GENE REPLICATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MEMORY CELL; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SOMATIC HYPERMUTATION; VDJ EXON;

EID: 33947705325     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.7.4322     Document Type: Article

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